LysM domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AQM9_LEIMU

TriTrypDb:

LmxM.16.0700

Length:

845

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQM9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQM9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	365	369	PF00656	0.524
CLV_C14_Caspase3-7	431	435	PF00656	0.668
CLV_C14_Caspase3-7	606	610	PF00656	0.533
CLV_NRD_NRD_1	442	444	PF00675	0.636
CLV_NRD_NRD_1	589	591	PF00675	0.585
CLV_NRD_NRD_1	697	699	PF00675	0.709
CLV_NRD_NRD_1	831	833	PF00675	0.664
CLV_PCSK_FUR_1	587	591	PF00082	0.548
CLV_PCSK_KEX2_1	444	446	PF00082	0.653
CLV_PCSK_KEX2_1	5	7	PF00082	0.530
CLV_PCSK_KEX2_1	589	591	PF00082	0.585
CLV_PCSK_KEX2_1	697	699	PF00082	0.709
CLV_PCSK_PC1ET2_1	444	446	PF00082	0.591
CLV_PCSK_PC1ET2_1	5	7	PF00082	0.486
CLV_PCSK_PC7_1	440	446	PF00082	0.652
CLV_PCSK_SKI1_1	459	463	PF00082	0.634
CLV_PCSK_SKI1_1	690	694	PF00082	0.651
CLV_Separin_Metazoa	517	521	PF03568	0.577
CLV_Separin_Metazoa	829	833	PF03568	0.639
DEG_APCC_DBOX_1	283	291	PF00400	0.672
DEG_COP1_1	320	330	PF00400	0.596
DEG_Nend_UBRbox_2	1	3	PF02207	0.551
DEG_SCF_TRCP1_1	237	243	PF00400	0.705
DEG_SPOP_SBC_1	138	142	PF00917	0.651
DEG_SPOP_SBC_1	190	194	PF00917	0.695
DEG_SPOP_SBC_1	599	603	PF00917	0.708
DOC_ANK_TNKS_1	503	510	PF00023	0.545
DOC_CKS1_1	580	585	PF01111	0.698
DOC_CKS1_1	691	696	PF01111	0.518
DOC_MAPK_MEF2A_6	392	401	PF00069	0.516
DOC_PP2B_LxvP_1	251	254	PF13499	0.640
DOC_PP2B_LxvP_1	468	471	PF13499	0.593
DOC_PP2B_LxvP_1	540	543	PF13499	0.639
DOC_PP4_FxxP_1	580	583	PF00568	0.697
DOC_PP4_FxxP_1	692	695	PF00568	0.643
DOC_PP4_MxPP_1	414	417	PF00568	0.596
DOC_PP4_MxPP_1	654	657	PF00568	0.707
DOC_USP7_MATH_1	129	133	PF00917	0.607
DOC_USP7_MATH_1	190	194	PF00917	0.695
DOC_USP7_MATH_1	206	210	PF00917	0.532
DOC_USP7_MATH_1	219	223	PF00917	0.565
DOC_USP7_MATH_1	311	315	PF00917	0.695
DOC_USP7_MATH_1	326	330	PF00917	0.564
DOC_USP7_MATH_1	347	351	PF00917	0.517
DOC_USP7_MATH_1	428	432	PF00917	0.610
DOC_USP7_MATH_1	451	455	PF00917	0.592
DOC_USP7_MATH_1	541	545	PF00917	0.667
DOC_USP7_MATH_1	562	566	PF00917	0.693
DOC_USP7_MATH_1	568	572	PF00917	0.662
DOC_USP7_MATH_1	599	603	PF00917	0.671
DOC_USP7_MATH_1	807	811	PF00917	0.587
DOC_USP7_MATH_2	34	40	PF00917	0.580
DOC_WW_Pin1_4	132	137	PF00397	0.625
DOC_WW_Pin1_4	141	146	PF00397	0.587
DOC_WW_Pin1_4	242	247	PF00397	0.705
DOC_WW_Pin1_4	277	282	PF00397	0.650
DOC_WW_Pin1_4	294	299	PF00397	0.499
DOC_WW_Pin1_4	318	323	PF00397	0.665
DOC_WW_Pin1_4	330	335	PF00397	0.665
DOC_WW_Pin1_4	352	357	PF00397	0.693
DOC_WW_Pin1_4	384	389	PF00397	0.682
DOC_WW_Pin1_4	419	424	PF00397	0.613
DOC_WW_Pin1_4	469	474	PF00397	0.649
DOC_WW_Pin1_4	482	487	PF00397	0.565
DOC_WW_Pin1_4	522	527	PF00397	0.678
DOC_WW_Pin1_4	534	539	PF00397	0.571
DOC_WW_Pin1_4	547	552	PF00397	0.597
DOC_WW_Pin1_4	573	578	PF00397	0.643
DOC_WW_Pin1_4	579	584	PF00397	0.657
DOC_WW_Pin1_4	608	613	PF00397	0.697
DOC_WW_Pin1_4	616	621	PF00397	0.623
DOC_WW_Pin1_4	630	635	PF00397	0.588
DOC_WW_Pin1_4	648	653	PF00397	0.550
DOC_WW_Pin1_4	663	668	PF00397	0.563
DOC_WW_Pin1_4	690	695	PF00397	0.556
DOC_WW_Pin1_4	699	704	PF00397	0.596
DOC_WW_Pin1_4	724	729	PF00397	0.624
DOC_WW_Pin1_4	732	737	PF00397	0.573
DOC_WW_Pin1_4	839	844	PF00397	0.702
LIG_14-3-3_CanoR_1	128	138	PF00244	0.680
LIG_14-3-3_CanoR_1	240	249	PF00244	0.549
LIG_14-3-3_CanoR_1	312	318	PF00244	0.738
LIG_14-3-3_CanoR_1	427	433	PF00244	0.548
LIG_14-3-3_CanoR_1	47	54	PF00244	0.536
LIG_14-3-3_CanoR_1	495	503	PF00244	0.679
LIG_14-3-3_CanoR_1	532	540	PF00244	0.581
LIG_14-3-3_CanoR_1	662	667	PF00244	0.644
LIG_14-3-3_CanoR_1	683	688	PF00244	0.653
LIG_14-3-3_CanoR_1	793	797	PF00244	0.221
LIG_BIR_III_2	715	719	PF00653	0.604
LIG_BRCT_BRCA1_1	214	218	PF00533	0.625
LIG_CtBP_PxDLS_1	668	672	PF00389	0.704
LIG_CtBP_PxDLS_1	728	732	PF00389	0.655
LIG_EVH1_1	725	729	PF00568	0.530
LIG_FHA_1	147	153	PF00498	0.589
LIG_FHA_1	396	402	PF00498	0.620
LIG_FHA_2	110	116	PF00498	0.485
LIG_FHA_2	30	36	PF00498	0.702
LIG_FHA_2	373	379	PF00498	0.585
LIG_FHA_2	779	785	PF00498	0.342
LIG_GBD_Chelix_1	37	45	PF00786	0.483
LIG_IBAR_NPY_1	786	788	PF08397	0.385
LIG_LIR_Apic_2	578	583	PF02991	0.694
LIG_LIR_Apic_2	614	620	PF02991	0.535
LIG_LIR_Gen_1	122	131	PF02991	0.572
LIG_LIR_Gen_1	746	754	PF02991	0.658
LIG_LIR_Gen_1	763	773	PF02991	0.262
LIG_LIR_Gen_1	9	20	PF02991	0.504
LIG_LIR_Nem_3	122	127	PF02991	0.542
LIG_LIR_Nem_3	283	288	PF02991	0.766
LIG_LIR_Nem_3	746	750	PF02991	0.662
LIG_LIR_Nem_3	763	768	PF02991	0.450
LIG_LIR_Nem_3	784	788	PF02991	0.385
LIG_LIR_Nem_3	9	15	PF02991	0.481
LIG_MYND_1	107	111	PF01753	0.431
LIG_MYND_1	328	332	PF01753	0.607
LIG_PALB2_WD40_1	519	527	PF16756	0.511
LIG_Pex14_1	357	361	PF04695	0.640
LIG_PTAP_UEV_1	717	722	PF05743	0.537
LIG_SH2_CRK	12	16	PF00017	0.490
LIG_SH2_CRK	530	534	PF00017	0.517
LIG_SH2_CRK	617	621	PF00017	0.534
LIG_SH2_NCK_1	617	621	PF00017	0.534
LIG_SH2_STAT5	124	127	PF00017	0.536
LIG_SH2_STAT5	286	289	PF00017	0.628
LIG_SH2_STAT5	641	644	PF00017	0.543
LIG_SH2_STAT5	788	791	PF00017	0.385
LIG_SH3_1	319	325	PF00018	0.524
LIG_SH3_3	104	110	PF00018	0.527
LIG_SH3_3	115	121	PF00018	0.443
LIG_SH3_3	131	137	PF00018	0.545
LIG_SH3_3	243	249	PF00018	0.737
LIG_SH3_3	275	281	PF00018	0.578
LIG_SH3_3	295	301	PF00018	0.549
LIG_SH3_3	319	325	PF00018	0.680
LIG_SH3_3	422	428	PF00018	0.568
LIG_SH3_3	481	487	PF00018	0.654
LIG_SH3_3	661	667	PF00018	0.709
LIG_SH3_3	697	703	PF00018	0.642
LIG_SH3_3	715	721	PF00018	0.593
LIG_SH3_3	723	729	PF00018	0.641
LIG_SH3_3	733	739	PF00018	0.538
LIG_SH3_3	794	800	PF00018	0.369
LIG_SUMO_SIM_anti_2	398	404	PF11976	0.516
LIG_SUMO_SIM_par_1	286	293	PF11976	0.677
LIG_SUMO_SIM_par_1	397	404	PF11976	0.514
LIG_TRAF2_1	362	365	PF00917	0.609
LIG_TYR_ITIM	10	15	PF00017	0.482
LIG_UBA3_1	287	291	PF00899	0.677
LIG_WW_3	694	698	PF00397	0.628
MOD_CDC14_SPxK_1	424	427	PF00782	0.546
MOD_CDC14_SPxK_1	472	475	PF00782	0.678
MOD_CDK_SPK_2	630	635	PF00069	0.674
MOD_CDK_SPxK_1	421	427	PF00069	0.546
MOD_CDK_SPxK_1	469	475	PF00069	0.681
MOD_CDK_SPxxK_3	141	148	PF00069	0.614
MOD_CDK_SPxxK_3	277	284	PF00069	0.611
MOD_CDK_SPxxK_3	547	554	PF00069	0.609
MOD_CDK_SPxxK_3	648	655	PF00069	0.703
MOD_CDK_SPxxK_3	690	697	PF00069	0.525
MOD_CK1_1	132	138	PF00069	0.673
MOD_CK1_1	140	146	PF00069	0.655
MOD_CK1_1	155	161	PF00069	0.545
MOD_CK1_1	164	170	PF00069	0.622
MOD_CK1_1	189	195	PF00069	0.693
MOD_CK1_1	196	202	PF00069	0.626
MOD_CK1_1	232	238	PF00069	0.656
MOD_CK1_1	242	248	PF00069	0.651
MOD_CK1_1	273	279	PF00069	0.632
MOD_CK1_1	297	303	PF00069	0.654
MOD_CK1_1	321	327	PF00069	0.670
MOD_CK1_1	371	377	PF00069	0.701
MOD_CK1_1	400	406	PF00069	0.588
MOD_CK1_1	446	452	PF00069	0.556
MOD_CK1_1	482	488	PF00069	0.679
MOD_CK1_1	498	504	PF00069	0.578
MOD_CK1_1	534	540	PF00069	0.656
MOD_CK1_1	544	550	PF00069	0.639
MOD_CK1_1	560	566	PF00069	0.564
MOD_CK1_1	611	617	PF00069	0.701
MOD_CK1_1	633	639	PF00069	0.684
MOD_CK1_1	674	680	PF00069	0.595
MOD_CK1_1	69	75	PF00069	0.668
MOD_CK1_1	727	733	PF00069	0.641
MOD_CK2_1	109	115	PF00069	0.540
MOD_CK2_1	347	353	PF00069	0.553
MOD_CK2_1	372	378	PF00069	0.702
MOD_CK2_1	633	639	PF00069	0.594
MOD_CK2_1	732	738	PF00069	0.701
MOD_CK2_1	778	784	PF00069	0.342
MOD_CK2_1	807	813	PF00069	0.597
MOD_CK2_1	87	93	PF00069	0.437
MOD_Cter_Amidation	587	590	PF01082	0.548
MOD_GlcNHglycan	158	161	PF01048	0.673
MOD_GlcNHglycan	163	166	PF01048	0.657
MOD_GlcNHglycan	167	170	PF01048	0.609
MOD_GlcNHglycan	188	191	PF01048	0.688
MOD_GlcNHglycan	214	217	PF01048	0.709
MOD_GlcNHglycan	231	234	PF01048	0.647
MOD_GlcNHglycan	237	240	PF01048	0.601
MOD_GlcNHglycan	315	318	PF01048	0.592
MOD_GlcNHglycan	349	352	PF01048	0.532
MOD_GlcNHglycan	445	448	PF01048	0.665
MOD_GlcNHglycan	453	456	PF01048	0.606
MOD_GlcNHglycan	481	484	PF01048	0.690
MOD_GlcNHglycan	497	500	PF01048	0.574
MOD_GlcNHglycan	533	536	PF01048	0.631
MOD_GlcNHglycan	559	562	PF01048	0.670
MOD_GlcNHglycan	570	573	PF01048	0.623
MOD_GlcNHglycan	613	616	PF01048	0.666
MOD_GlcNHglycan	68	71	PF01048	0.681
MOD_GlcNHglycan	81	84	PF01048	0.689
MOD_GSK3_1	137	144	PF00069	0.685
MOD_GSK3_1	152	159	PF00069	0.553
MOD_GSK3_1	161	168	PF00069	0.612
MOD_GSK3_1	186	193	PF00069	0.686
MOD_GSK3_1	235	242	PF00069	0.725
MOD_GSK3_1	249	256	PF00069	0.624
MOD_GSK3_1	273	280	PF00069	0.692
MOD_GSK3_1	326	333	PF00069	0.607
MOD_GSK3_1	338	345	PF00069	0.528
MOD_GSK3_1	368	375	PF00069	0.697
MOD_GSK3_1	384	391	PF00069	0.548
MOD_GSK3_1	397	404	PF00069	0.621
MOD_GSK3_1	475	482	PF00069	0.687
MOD_GSK3_1	541	548	PF00069	0.690
MOD_GSK3_1	575	582	PF00069	0.632
MOD_GSK3_1	599	606	PF00069	0.679
MOD_GSK3_1	611	618	PF00069	0.616
MOD_GSK3_1	671	678	PF00069	0.551
MOD_GSK3_1	679	686	PF00069	0.531
MOD_GSK3_1	69	76	PF00069	0.738
MOD_N-GLC_1	419	424	PF02516	0.548
MOD_N-GLC_1	669	674	PF02516	0.711
MOD_N-GLC_1	775	780	PF02516	0.385
MOD_N-GLC_2	255	257	PF02516	0.639
MOD_NEK2_1	272	277	PF00069	0.554
MOD_NEK2_1	337	342	PF00069	0.519
MOD_NEK2_1	397	402	PF00069	0.556
MOD_NEK2_1	600	605	PF00069	0.711
MOD_NEK2_1	613	618	PF00069	0.586
MOD_NEK2_1	671	676	PF00069	0.607
MOD_NEK2_1	754	759	PF00069	0.591
MOD_NEK2_1	777	782	PF00069	0.342
MOD_NEK2_1	95	100	PF00069	0.592
MOD_PIKK_1	191	197	PF00454	0.528
MOD_PIKK_1	224	230	PF00454	0.665
MOD_PIKK_1	671	677	PF00454	0.552
MOD_PIKK_1	754	760	PF00454	0.594
MOD_PK_1	475	481	PF00069	0.631
MOD_PKA_1	443	449	PF00069	0.658
MOD_PKA_2	197	203	PF00069	0.631
MOD_PKA_2	229	235	PF00069	0.686
MOD_PKA_2	239	245	PF00069	0.568
MOD_PKA_2	311	317	PF00069	0.653
MOD_PKA_2	46	52	PF00069	0.530
MOD_PKA_2	474	480	PF00069	0.639
MOD_PKA_2	531	537	PF00069	0.587
MOD_PKA_2	66	72	PF00069	0.661
MOD_PKA_2	682	688	PF00069	0.653
MOD_PKA_2	792	798	PF00069	0.331
MOD_PKB_1	380	388	PF00069	0.601
MOD_Plk_1	249	255	PF00069	0.750
MOD_Plk_1	475	481	PF00069	0.631
MOD_Plk_1	775	781	PF00069	0.385
MOD_Plk_2-3	764	770	PF00069	0.342
MOD_Plk_4	120	126	PF00069	0.680
MOD_Plk_4	206	212	PF00069	0.511
MOD_Plk_4	778	784	PF00069	0.342
MOD_Plk_4	818	824	PF00069	0.583
MOD_ProDKin_1	132	138	PF00069	0.626
MOD_ProDKin_1	141	147	PF00069	0.587
MOD_ProDKin_1	242	248	PF00069	0.704
MOD_ProDKin_1	277	283	PF00069	0.650
MOD_ProDKin_1	294	300	PF00069	0.502
MOD_ProDKin_1	318	324	PF00069	0.667
MOD_ProDKin_1	330	336	PF00069	0.663
MOD_ProDKin_1	352	358	PF00069	0.694
MOD_ProDKin_1	384	390	PF00069	0.681
MOD_ProDKin_1	419	425	PF00069	0.608
MOD_ProDKin_1	469	475	PF00069	0.650
MOD_ProDKin_1	482	488	PF00069	0.565
MOD_ProDKin_1	522	528	PF00069	0.677
MOD_ProDKin_1	534	540	PF00069	0.572
MOD_ProDKin_1	547	553	PF00069	0.597
MOD_ProDKin_1	573	579	PF00069	0.646
MOD_ProDKin_1	608	614	PF00069	0.698
MOD_ProDKin_1	616	622	PF00069	0.624
MOD_ProDKin_1	630	636	PF00069	0.589
MOD_ProDKin_1	648	654	PF00069	0.553
MOD_ProDKin_1	663	669	PF00069	0.562
MOD_ProDKin_1	690	696	PF00069	0.552
MOD_ProDKin_1	699	705	PF00069	0.598
MOD_ProDKin_1	724	730	PF00069	0.626
MOD_ProDKin_1	732	738	PF00069	0.573
MOD_ProDKin_1	839	845	PF00069	0.706
TRG_DiLeu_BaEn_1	818	823	PF01217	0.594
TRG_ENDOCYTIC_2	12	15	PF00928	0.485
TRG_ENDOCYTIC_2	124	127	PF00928	0.536
TRG_ENDOCYTIC_2	285	288	PF00928	0.769
TRG_ENDOCYTIC_2	530	533	PF00928	0.518
TRG_ENDOCYTIC_2	765	768	PF00928	0.385
TRG_ER_diArg_1	148	151	PF00400	0.714
TRG_ER_diArg_1	379	382	PF00400	0.737
TRG_ER_diArg_1	442	445	PF00400	0.657
TRG_ER_diArg_1	587	590	PF00400	0.600
TRG_ER_diArg_1	696	698	PF00400	0.693
TRG_NES_CRM1_1	86	101	PF08389	0.490
TRG_NLS_MonoExtN_4	440	447	PF00514	0.588
TRG_NLS_MonoExtN_4	787	794	PF00514	0.331

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IJ04	Leishmania donovani	83%	100%
A4H8J2	Leishmania braziliensis	62%	100%
A4HWW7	Leishmania infantum	83%	100%
Q4QEU9	Leishmania major	82%	100%