Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AQM1_LEIMU

TriTrypDb:

LmxM.16.0620

Length:

1133

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQM1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQM1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	174	178	PF00656	0.826
CLV_C14_Caspase3-7	321	325	PF00656	0.527
CLV_C14_Caspase3-7	400	404	PF00656	0.601
CLV_C14_Caspase3-7	889	893	PF00656	0.760
CLV_MEL_PAP_1	47	53	PF00089	0.650
CLV_NRD_NRD_1	153	155	PF00675	0.769
CLV_NRD_NRD_1	237	239	PF00675	0.855
CLV_NRD_NRD_1	316	318	PF00675	0.695
CLV_NRD_NRD_1	494	496	PF00675	0.564
CLV_NRD_NRD_1	541	543	PF00675	0.808
CLV_NRD_NRD_1	620	622	PF00675	0.490
CLV_NRD_NRD_1	876	878	PF00675	0.612
CLV_PCSK_FUR_1	863	867	PF00082	0.559
CLV_PCSK_FUR_1	914	918	PF00082	0.581
CLV_PCSK_KEX2_1	153	155	PF00082	0.619
CLV_PCSK_KEX2_1	239	241	PF00082	0.860
CLV_PCSK_KEX2_1	316	318	PF00082	0.772
CLV_PCSK_KEX2_1	494	496	PF00082	0.564
CLV_PCSK_KEX2_1	541	543	PF00082	0.808
CLV_PCSK_KEX2_1	620	622	PF00082	0.490
CLV_PCSK_KEX2_1	865	867	PF00082	0.629
CLV_PCSK_KEX2_1	876	878	PF00082	0.592
CLV_PCSK_KEX2_1	916	918	PF00082	0.673
CLV_PCSK_PC1ET2_1	239	241	PF00082	0.860
CLV_PCSK_PC1ET2_1	865	867	PF00082	0.561
CLV_PCSK_PC1ET2_1	916	918	PF00082	0.673
CLV_PCSK_PC7_1	872	878	PF00082	0.561
CLV_PCSK_SKI1_1	1086	1090	PF00082	0.770
CLV_PCSK_SKI1_1	26	30	PF00082	0.441
CLV_PCSK_SKI1_1	268	272	PF00082	0.640
CLV_PCSK_SKI1_1	329	333	PF00082	0.635
CLV_PCSK_SKI1_1	363	367	PF00082	0.530
CLV_PCSK_SKI1_1	660	664	PF00082	0.481
CLV_PCSK_SKI1_1	876	880	PF00082	0.556
DEG_APCC_DBOX_1	25	33	PF00400	0.436
DEG_COP1_1	562	571	PF00400	0.545
DEG_SCF_TRCP1_1	702	707	PF00400	0.640
DEG_SPOP_SBC_1	207	211	PF00917	0.749
DOC_ANK_TNKS_1	175	182	PF00023	0.560
DOC_CKS1_1	465	470	PF01111	0.546
DOC_CYCLIN_yCln2_LP_2	336	342	PF00134	0.737
DOC_CYCLIN_yCln2_LP_2	424	430	PF00134	0.713
DOC_MAPK_gen_1	1031	1039	PF00069	0.767
DOC_MAPK_gen_1	1105	1112	PF00069	0.613
DOC_MAPK_gen_1	327	336	PF00069	0.723
DOC_MAPK_gen_1	658	666	PF00069	0.484
DOC_MAPK_MEF2A_6	1105	1112	PF00069	0.713
DOC_MAPK_MEF2A_6	845	854	PF00069	0.812
DOC_MAPK_NFAT4_5	1105	1113	PF00069	0.587
DOC_PP2B_LxvP_1	334	337	PF13499	0.722
DOC_PP2B_LxvP_1	549	552	PF13499	0.547
DOC_PP2B_LxvP_1	63	66	PF13499	0.543
DOC_PP4_FxxP_1	282	285	PF00568	0.644
DOC_PP4_FxxP_1	350	353	PF00568	0.633
DOC_PP4_FxxP_1	465	468	PF00568	0.765
DOC_PP4_FxxP_1	769	772	PF00568	0.477
DOC_USP7_MATH_1	1040	1044	PF00917	0.611
DOC_USP7_MATH_1	1079	1083	PF00917	0.658
DOC_USP7_MATH_1	1088	1092	PF00917	0.745
DOC_USP7_MATH_1	115	119	PF00917	0.788
DOC_USP7_MATH_1	205	209	PF00917	0.675
DOC_USP7_MATH_1	223	227	PF00917	0.657
DOC_USP7_MATH_1	555	559	PF00917	0.763
DOC_USP7_MATH_1	569	573	PF00917	0.604
DOC_USP7_MATH_1	578	582	PF00917	0.776
DOC_USP7_MATH_1	670	674	PF00917	0.707
DOC_USP7_MATH_1	700	704	PF00917	0.668
DOC_USP7_MATH_1	764	768	PF00917	0.593
DOC_USP7_MATH_1	886	890	PF00917	0.723
DOC_USP7_MATH_1	896	900	PF00917	0.577
DOC_USP7_MATH_1	948	952	PF00917	0.788
DOC_WW_Pin1_4	105	110	PF00397	0.776
DOC_WW_Pin1_4	1075	1080	PF00397	0.767
DOC_WW_Pin1_4	1092	1097	PF00397	0.618
DOC_WW_Pin1_4	116	121	PF00397	0.706
DOC_WW_Pin1_4	216	221	PF00397	0.758
DOC_WW_Pin1_4	233	238	PF00397	0.555
DOC_WW_Pin1_4	268	273	PF00397	0.628
DOC_WW_Pin1_4	335	340	PF00397	0.733
DOC_WW_Pin1_4	371	376	PF00397	0.826
DOC_WW_Pin1_4	41	46	PF00397	0.787
DOC_WW_Pin1_4	423	428	PF00397	0.775
DOC_WW_Pin1_4	429	434	PF00397	0.716
DOC_WW_Pin1_4	464	469	PF00397	0.751
DOC_WW_Pin1_4	481	486	PF00397	0.698
DOC_WW_Pin1_4	561	566	PF00397	0.768
DOC_WW_Pin1_4	610	615	PF00397	0.748
DOC_WW_Pin1_4	78	83	PF00397	0.719
DOC_WW_Pin1_4	836	841	PF00397	0.745
DOC_WW_Pin1_4	897	902	PF00397	0.751
DOC_WW_Pin1_4	906	911	PF00397	0.715
DOC_WW_Pin1_4	926	931	PF00397	0.770
DOC_WW_Pin1_4	93	98	PF00397	0.579
LIG_14-3-3_CanoR_1	1080	1085	PF00244	0.626
LIG_14-3-3_CanoR_1	329	335	PF00244	0.749
LIG_14-3-3_CanoR_1	470	478	PF00244	0.647
LIG_14-3-3_CanoR_1	494	500	PF00244	0.623
LIG_14-3-3_CanoR_1	541	545	PF00244	0.810
LIG_14-3-3_CanoR_1	563	569	PF00244	0.699
LIG_14-3-3_CanoR_1	801	810	PF00244	0.543
LIG_14-3-3_CanoR_1	845	849	PF00244	0.811
LIG_14-3-3_CanoR_1	876	885	PF00244	0.548
LIG_14-3-3_CanoR_1	965	972	PF00244	0.600
LIG_14-3-3_CanoR_1	974	980	PF00244	0.668
LIG_Actin_WH2_2	14	32	PF00022	0.452
LIG_BIR_II_1	1	5	PF00653	0.812
LIG_BIR_III_2	892	896	PF00653	0.746
LIG_BIR_III_4	435	439	PF00653	0.549
LIG_BIR_III_4	84	88	PF00653	0.676
LIG_BRCT_BRCA1_1	220	224	PF00533	0.619
LIG_BRCT_BRCA1_1	497	501	PF00533	0.524
LIG_deltaCOP1_diTrp_1	937	940	PF00928	0.510
LIG_FHA_1	1096	1102	PF00498	0.761
LIG_FHA_1	1125	1131	PF00498	0.725
LIG_FHA_1	123	129	PF00498	0.766
LIG_FHA_1	155	161	PF00498	0.776
LIG_FHA_1	189	195	PF00498	0.775
LIG_FHA_1	209	215	PF00498	0.515
LIG_FHA_1	269	275	PF00498	0.513
LIG_FHA_1	331	337	PF00498	0.594
LIG_FHA_1	419	425	PF00498	0.748
LIG_FHA_1	470	476	PF00498	0.645
LIG_FHA_1	59	65	PF00498	0.647
LIG_FHA_1	661	667	PF00498	0.704
LIG_FHA_1	812	818	PF00498	0.575
LIG_FHA_1	877	883	PF00498	0.567
LIG_FHA_1	966	972	PF00498	0.745
LIG_FHA_1	974	980	PF00498	0.525
LIG_FHA_2	1021	1027	PF00498	0.755
LIG_FHA_2	259	265	PF00498	0.691
LIG_FHA_2	316	322	PF00498	0.501
LIG_FHA_2	41	47	PF00498	0.590
LIG_FHA_2	430	436	PF00498	0.820
LIG_FHA_2	520	526	PF00498	0.481
LIG_FHA_2	641	647	PF00498	0.867
LIG_FHA_2	681	687	PF00498	0.737
LIG_FXI_DFP_1	459	463	PF00024	0.565
LIG_Integrin_RGD_1	584	586	PF01839	0.826
LIG_LIR_Apic_2	464	468	PF02991	0.746
LIG_LIR_Apic_2	767	772	PF02991	0.594
LIG_LIR_Gen_1	221	232	PF02991	0.543
LIG_LIR_Gen_1	260	270	PF02991	0.540
LIG_LIR_Gen_1	403	414	PF02991	0.593
LIG_LIR_Gen_1	628	638	PF02991	0.826
LIG_LIR_Gen_1	937	944	PF02991	0.723
LIG_LIR_Nem_3	104	110	PF02991	0.601
LIG_LIR_Nem_3	221	227	PF02991	0.537
LIG_LIR_Nem_3	260	265	PF02991	0.544
LIG_LIR_Nem_3	392	397	PF02991	0.748
LIG_LIR_Nem_3	403	409	PF02991	0.525
LIG_LIR_Nem_3	461	465	PF02991	0.640
LIG_LIR_Nem_3	528	532	PF02991	0.792
LIG_LIR_Nem_3	628	634	PF02991	0.827
LIG_LIR_Nem_3	937	941	PF02991	0.719
LIG_MYND_1	930	934	PF01753	0.706
LIG_REV1ctd_RIR_1	499	509	PF16727	0.523
LIG_SH2_PTP2	631	634	PF00017	0.833
LIG_SH2_STAP1	1128	1132	PF00017	0.734
LIG_SH2_STAT5	631	634	PF00017	0.833
LIG_SH2_STAT5	779	782	PF00017	0.600
LIG_SH3_3	106	112	PF00018	0.785
LIG_SH3_3	201	207	PF00018	0.784
LIG_SH3_3	21	27	PF00018	0.739
LIG_SH3_3	39	45	PF00018	0.496
LIG_SH3_3	449	455	PF00018	0.796
LIG_SH3_3	548	554	PF00018	0.551
LIG_SH3_3	927	933	PF00018	0.682
LIG_SH3_3	980	986	PF00018	0.708
LIG_SH3_3	998	1004	PF00018	0.468
LIG_SUMO_SIM_anti_2	208	219	PF11976	0.519
LIG_SUMO_SIM_anti_2	61	67	PF11976	0.547
LIG_SUMO_SIM_anti_2	612	619	PF11976	0.733
LIG_SUMO_SIM_par_1	332	338	PF11976	0.508
LIG_SUMO_SIM_par_1	61	67	PF11976	0.547
LIG_TRAF2_1	1004	1007	PF00917	0.673
LIG_TRAF2_1	1091	1094	PF00917	0.771
LIG_TRAF2_1	261	264	PF00917	0.662
LIG_TRAF2_1	909	912	PF00917	0.691
LIG_WRC_WIRS_1	462	467	PF05994	0.563
LIG_WW_3	467	471	PF00397	0.750
LIG_WW_3	550	554	PF00397	0.556
MOD_CDC14_SPxK_1	338	341	PF00782	0.651
MOD_CDK_SPK_2	1075	1080	PF00069	0.670
MOD_CDK_SPK_2	233	238	PF00069	0.673
MOD_CDK_SPK_2	926	931	PF00069	0.770
MOD_CDK_SPxK_1	233	239	PF00069	0.675
MOD_CDK_SPxK_1	335	341	PF00069	0.677
MOD_CDK_SPxK_1	464	470	PF00069	0.547
MOD_CDK_SPxxK_3	233	240	PF00069	0.677
MOD_CK1_1	1071	1077	PF00069	0.783
MOD_CK1_1	208	214	PF00069	0.761
MOD_CK1_1	219	225	PF00069	0.642
MOD_CK1_1	226	232	PF00069	0.555
MOD_CK1_1	335	341	PF00069	0.660
MOD_CK1_1	464	470	PF00069	0.611
MOD_CK1_1	481	487	PF00069	0.749
MOD_CK1_1	564	570	PF00069	0.824
MOD_CK1_1	673	679	PF00069	0.584
MOD_CK1_1	687	693	PF00069	0.568
MOD_CK1_1	748	754	PF00069	0.773
MOD_CK1_1	757	763	PF00069	0.663
MOD_CK1_1	804	810	PF00069	0.558
MOD_CK1_1	839	845	PF00069	0.742
MOD_CK1_1	884	890	PF00069	0.752
MOD_CK1_1	899	905	PF00069	0.857
MOD_CK1_1	91	97	PF00069	0.722
MOD_CK1_1	946	952	PF00069	0.549
MOD_CK2_1	1079	1085	PF00069	0.670
MOD_CK2_1	1088	1094	PF00069	0.762
MOD_CK2_1	168	174	PF00069	0.791
MOD_CK2_1	258	264	PF00069	0.635
MOD_CK2_1	315	321	PF00069	0.491
MOD_CK2_1	40	46	PF00069	0.587
MOD_CK2_1	640	646	PF00069	0.712
MOD_CK2_1	764	770	PF00069	0.507
MOD_CK2_1	906	912	PF00069	0.734
MOD_CMANNOS	504	507	PF00535	0.739
MOD_Cter_Amidation	492	495	PF01082	0.549
MOD_DYRK1A_RPxSP_1	268	272	PF00069	0.640
MOD_GlcNHglycan	1	4	PF01048	0.765
MOD_GlcNHglycan	1056	1059	PF01048	0.813
MOD_GlcNHglycan	1073	1076	PF01048	0.560
MOD_GlcNHglycan	13	16	PF01048	0.617
MOD_GlcNHglycan	164	167	PF01048	0.763
MOD_GlcNHglycan	221	224	PF01048	0.764
MOD_GlcNHglycan	409	412	PF01048	0.628
MOD_GlcNHglycan	481	484	PF01048	0.828
MOD_GlcNHglycan	497	500	PF01048	0.531
MOD_GlcNHglycan	509	512	PF01048	0.542
MOD_GlcNHglycan	557	560	PF01048	0.865
MOD_GlcNHglycan	569	572	PF01048	0.639
MOD_GlcNHglycan	580	583	PF01048	0.560
MOD_GlcNHglycan	668	671	PF01048	0.730
MOD_GlcNHglycan	672	675	PF01048	0.657
MOD_GlcNHglycan	686	689	PF01048	0.524
MOD_GlcNHglycan	702	705	PF01048	0.604
MOD_GlcNHglycan	756	759	PF01048	0.734
MOD_GlcNHglycan	782	785	PF01048	0.546
MOD_GlcNHglycan	803	806	PF01048	0.837
MOD_GlcNHglycan	866	869	PF01048	0.771
MOD_GlcNHglycan	888	891	PF01048	0.758
MOD_GlcNHglycan	901	904	PF01048	0.538
MOD_GlcNHglycan	926	929	PF01048	0.671
MOD_GlcNHglycan	997	1000	PF01048	0.789
MOD_GSK3_1	1071	1078	PF00069	0.808
MOD_GSK3_1	1088	1095	PF00069	0.531
MOD_GSK3_1	181	188	PF00069	0.564
MOD_GSK3_1	206	213	PF00069	0.772
MOD_GSK3_1	214	221	PF00069	0.645
MOD_GSK3_1	37	44	PF00069	0.568
MOD_GSK3_1	377	384	PF00069	0.769
MOD_GSK3_1	555	562	PF00069	0.860
MOD_GSK3_1	645	652	PF00069	0.726
MOD_GSK3_1	666	673	PF00069	0.611
MOD_GSK3_1	67	74	PF00069	0.794
MOD_GSK3_1	680	687	PF00069	0.586
MOD_GSK3_1	700	707	PF00069	0.561
MOD_GSK3_1	744	751	PF00069	0.755
MOD_GSK3_1	753	760	PF00069	0.666
MOD_GSK3_1	796	803	PF00069	0.709
MOD_GSK3_1	836	843	PF00069	0.672
MOD_GSK3_1	876	883	PF00069	0.658
MOD_GSK3_1	89	96	PF00069	0.682
MOD_GSK3_1	939	946	PF00069	0.592
MOD_GSK3_1	960	967	PF00069	0.709
MOD_GSK3_1	97	104	PF00069	0.601
MOD_LATS_1	874	880	PF00433	0.557
MOD_N-GLC_1	215	220	PF02516	0.595
MOD_N-GLC_1	37	42	PF02516	0.684
MOD_N-GLC_1	377	382	PF02516	0.671
MOD_NEK2_1	214	219	PF00069	0.597
MOD_NEK2_1	280	285	PF00069	0.771
MOD_NEK2_1	478	483	PF00069	0.639
MOD_NEK2_1	519	524	PF00069	0.481
MOD_NEK2_1	557	562	PF00069	0.847
MOD_NEK2_1	588	593	PF00069	0.746
MOD_NEK2_1	684	689	PF00069	0.743
MOD_NEK2_1	780	785	PF00069	0.565
MOD_NEK2_1	881	886	PF00069	0.538
MOD_NEK2_2	680	685	PF00069	0.611
MOD_NEK2_2	844	849	PF00069	0.655
MOD_PIKK_1	436	442	PF00454	0.821
MOD_PIKK_1	966	972	PF00454	0.548
MOD_PK_1	1080	1086	PF00069	0.560
MOD_PKA_1	876	882	PF00069	0.553
MOD_PKA_2	1068	1074	PF00069	0.575
MOD_PKA_2	1079	1085	PF00069	0.599
MOD_PKA_2	315	321	PF00069	0.532
MOD_PKA_2	351	357	PF00069	0.520
MOD_PKA_2	436	442	PF00069	0.774
MOD_PKA_2	469	475	PF00069	0.641
MOD_PKA_2	540	546	PF00069	0.808
MOD_PKA_2	578	584	PF00069	0.528
MOD_PKA_2	764	770	PF00069	0.737
MOD_PKA_2	780	786	PF00069	0.626
MOD_PKA_2	800	806	PF00069	0.609
MOD_PKA_2	844	850	PF00069	0.811
MOD_PKA_2	876	882	PF00069	0.553
MOD_PKA_2	964	970	PF00069	0.621
MOD_PKA_2	973	979	PF00069	0.676
MOD_PKB_1	361	369	PF00069	0.535
MOD_PKB_1	658	666	PF00069	0.484
MOD_Plk_1	1025	1031	PF00069	0.770
MOD_Plk_1	123	129	PF00069	0.766
MOD_Plk_1	363	369	PF00069	0.541
MOD_Plk_1	37	43	PF00069	0.686
MOD_Plk_1	389	395	PF00069	0.494
MOD_Plk_1	625	631	PF00069	0.812
MOD_Plk_1	660	666	PF00069	0.620
MOD_Plk_1	690	696	PF00069	0.754
MOD_Plk_2-3	1068	1074	PF00069	0.736
MOD_Plk_4	1040	1046	PF00069	0.603
MOD_Plk_4	199	205	PF00069	0.715
MOD_Plk_4	210	216	PF00069	0.595
MOD_Plk_4	389	395	PF00069	0.494
MOD_Plk_4	58	64	PF00069	0.632
MOD_ProDKin_1	105	111	PF00069	0.777
MOD_ProDKin_1	1075	1081	PF00069	0.766
MOD_ProDKin_1	1092	1098	PF00069	0.617
MOD_ProDKin_1	116	122	PF00069	0.698
MOD_ProDKin_1	216	222	PF00069	0.760
MOD_ProDKin_1	233	239	PF00069	0.557
MOD_ProDKin_1	268	274	PF00069	0.626
MOD_ProDKin_1	335	341	PF00069	0.732
MOD_ProDKin_1	371	377	PF00069	0.828
MOD_ProDKin_1	41	47	PF00069	0.789
MOD_ProDKin_1	423	429	PF00069	0.780
MOD_ProDKin_1	464	470	PF00069	0.750
MOD_ProDKin_1	481	487	PF00069	0.700
MOD_ProDKin_1	561	567	PF00069	0.766
MOD_ProDKin_1	610	616	PF00069	0.744
MOD_ProDKin_1	78	84	PF00069	0.720
MOD_ProDKin_1	836	842	PF00069	0.746
MOD_ProDKin_1	897	903	PF00069	0.752
MOD_ProDKin_1	906	912	PF00069	0.715
MOD_ProDKin_1	926	932	PF00069	0.766
MOD_ProDKin_1	93	99	PF00069	0.580
MOD_SUMO_for_1	253	256	PF00179	0.528
MOD_SUMO_for_1	713	716	PF00179	0.610
TRG_DiLeu_BaLyEn_6	24	29	PF01217	0.731
TRG_ENDOCYTIC_2	631	634	PF00928	0.833
TRG_ER_diArg_1	1034	1037	PF00400	0.766
TRG_ER_diArg_1	1105	1108	PF00400	0.660
TRG_ER_diArg_1	153	155	PF00400	0.615
TRG_ER_diArg_1	237	240	PF00400	0.858
TRG_ER_diArg_1	619	621	PF00400	0.502
TRG_ER_diArg_1	657	660	PF00400	0.499
TRG_ER_diArg_1	876	878	PF00400	0.571
TRG_NLS_MonoExtC_3	237	242	PF00514	0.856
TRG_NLS_MonoExtN_4	237	243	PF00514	0.847
TRG_NLS_MonoExtN_4	914	920	PF00514	0.659
TRG_Pf-PMV_PEXEL_1	1022	1026	PF00026	0.752
TRG_Pf-PMV_PEXEL_1	341	345	PF00026	0.643
TRG_Pf-PMV_PEXEL_1	542	547	PF00026	0.813

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8I9D3	Leishmania donovani	78%	100%
A4H8I4	Leishmania braziliensis	60%	99%
A4HWW1	Leishmania infantum	78%	100%
Q4QEV7	Leishmania major	76%	100%