Argininosuccinate synthase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

carbamoyl-phosphate synthase, putative

Species:

Leishmania mexicana

UniProt:

E9AQL8_LEIMU

TriTrypDb:

LmxM.16.0590

Length:

1842

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AQL8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006082	organic acid metabolic process	3	10
GO:0006139	nucleobase-containing compound metabolic process	3	10
GO:0006206	pyrimidine nucleobase metabolic process	5	10
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	7	10
GO:0006520	amino acid metabolic process	3	10
GO:0006525	arginine metabolic process	6	10
GO:0006526	arginine biosynthetic process	7	10
GO:0006541	glutamine metabolic process	6	10
GO:0006725	cellular aromatic compound metabolic process	3	10
GO:0006807	nitrogen compound metabolic process	2	10
GO:0008152	metabolic process	1	10
GO:0008652	amino acid biosynthetic process	4	10
GO:0009058	biosynthetic process	2	10
GO:0009064	glutamine family amino acid metabolic process	5	10
GO:0009084	glutamine family amino acid biosynthetic process	6	10
GO:0009112	nucleobase metabolic process	4	10
GO:0009987	cellular process	1	10
GO:0016053	organic acid biosynthetic process	4	10
GO:0018130	heterocycle biosynthetic process	4	10
GO:0019752	carboxylic acid metabolic process	5	10
GO:0019856	pyrimidine nucleobase biosynthetic process	6	10
GO:0034641	cellular nitrogen compound metabolic process	3	10
GO:0043436	oxoacid metabolic process	4	10
GO:0044237	cellular metabolic process	2	10
GO:0044238	primary metabolic process	2	10
GO:0044249	cellular biosynthetic process	3	10
GO:0044271	cellular nitrogen compound biosynthetic process	4	10
GO:0044281	small molecule metabolic process	2	10
GO:0044283	small molecule biosynthetic process	3	10
GO:0046112	nucleobase biosynthetic process	5	10
GO:0046394	carboxylic acid biosynthetic process	5	10
GO:0046483	heterocycle metabolic process	3	10
GO:0055086	nucleobase-containing small molecule metabolic process	3	10
GO:0071704	organic substance metabolic process	2	10
GO:0072527	pyrimidine-containing compound metabolic process	4	10
GO:0072528	pyrimidine-containing compound biosynthetic process	5	10
GO:1901360	organic cyclic compound metabolic process	3	10
GO:1901362	organic cyclic compound biosynthetic process	4	10
GO:1901564	organonitrogen compound metabolic process	3	10
GO:1901566	organonitrogen compound biosynthetic process	4	10
GO:1901576	organic substance biosynthetic process	3	10
GO:1901605	alpha-amino acid metabolic process	4	10
GO:1901607	alpha-amino acid biosynthetic process	5	10

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	10
GO:0003824	catalytic activity	1	10
GO:0004055	argininosuccinate synthase activity	4	10
GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	5	10
GO:0005488	binding	1	10
GO:0005524	ATP binding	5	10
GO:0016874	ligase activity	2	10
GO:0016879	ligase activity, forming carbon-nitrogen bonds	3	10
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	4	10
GO:0017076	purine nucleotide binding	4	10
GO:0030554	adenyl nucleotide binding	5	10
GO:0032553	ribonucleotide binding	3	10
GO:0032555	purine ribonucleotide binding	4	10
GO:0032559	adenyl ribonucleotide binding	5	10
GO:0035639	purine ribonucleoside triphosphate binding	4	10
GO:0036094	small molecule binding	2	10
GO:0043167	ion binding	2	10
GO:0043168	anion binding	3	10
GO:0043169	cation binding	3	10
GO:0046872	metal ion binding	4	10
GO:0097159	organic cyclic compound binding	2	10
GO:0097367	carbohydrate derivative binding	2	10
GO:1901265	nucleoside phosphate binding	3	10
GO:1901363	heterocyclic compound binding	2	10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	446	450	PF00656	0.374
CLV_C14_Caspase3-7	82	86	PF00656	0.488
CLV_NRD_NRD_1	115	117	PF00675	0.284
CLV_NRD_NRD_1	1234	1236	PF00675	0.413
CLV_NRD_NRD_1	1329	1331	PF00675	0.344
CLV_NRD_NRD_1	1394	1396	PF00675	0.267
CLV_NRD_NRD_1	1400	1402	PF00675	0.242
CLV_NRD_NRD_1	1414	1416	PF00675	0.145
CLV_NRD_NRD_1	1573	1575	PF00675	0.289
CLV_NRD_NRD_1	1627	1629	PF00675	0.261
CLV_NRD_NRD_1	1814	1816	PF00675	0.577
CLV_NRD_NRD_1	372	374	PF00675	0.334
CLV_NRD_NRD_1	878	880	PF00675	0.360
CLV_NRD_NRD_1	952	954	PF00675	0.315
CLV_PCSK_FUR_1	1391	1395	PF00082	0.244
CLV_PCSK_FUR_1	1571	1575	PF00082	0.288
CLV_PCSK_FUR_1	876	880	PF00082	0.357
CLV_PCSK_KEX2_1	1169	1171	PF00082	0.260
CLV_PCSK_KEX2_1	1244	1246	PF00082	0.390
CLV_PCSK_KEX2_1	1329	1331	PF00082	0.344
CLV_PCSK_KEX2_1	1393	1395	PF00082	0.264
CLV_PCSK_KEX2_1	1400	1402	PF00082	0.280
CLV_PCSK_KEX2_1	1414	1416	PF00082	0.208
CLV_PCSK_KEX2_1	1573	1575	PF00082	0.308
CLV_PCSK_KEX2_1	1814	1816	PF00082	0.492
CLV_PCSK_KEX2_1	878	880	PF00082	0.354
CLV_PCSK_KEX2_1	952	954	PF00082	0.315
CLV_PCSK_PC1ET2_1	1169	1171	PF00082	0.260
CLV_PCSK_PC1ET2_1	1244	1246	PF00082	0.414
CLV_PCSK_PC1ET2_1	1393	1395	PF00082	0.253
CLV_PCSK_SKI1_1	1098	1102	PF00082	0.260
CLV_PCSK_SKI1_1	1244	1248	PF00082	0.383
CLV_PCSK_SKI1_1	1293	1297	PF00082	0.333
CLV_PCSK_SKI1_1	1305	1309	PF00082	0.362
CLV_PCSK_SKI1_1	1330	1334	PF00082	0.338
CLV_PCSK_SKI1_1	1781	1785	PF00082	0.260
CLV_PCSK_SKI1_1	194	198	PF00082	0.243
CLV_PCSK_SKI1_1	240	244	PF00082	0.243
CLV_PCSK_SKI1_1	247	251	PF00082	0.243
CLV_PCSK_SKI1_1	373	377	PF00082	0.354
CLV_PCSK_SKI1_1	494	498	PF00082	0.243
CLV_PCSK_SKI1_1	687	691	PF00082	0.243
CLV_PCSK_SKI1_1	692	696	PF00082	0.243
CLV_PCSK_SKI1_1	800	804	PF00082	0.312
CLV_PCSK_SKI1_1	819	823	PF00082	0.153
CLV_PCSK_SKI1_1	957	961	PF00082	0.357
CLV_Separin_Metazoa	582	586	PF03568	0.443
CLV_Separin_Metazoa	845	849	PF03568	0.544
DEG_APCC_DBOX_1	497	505	PF00400	0.443
DEG_APCC_DBOX_1	818	826	PF00400	0.514
DEG_APCC_DBOX_1	847	855	PF00400	0.494
DEG_APCC_DBOX_1	878	886	PF00400	0.491
DEG_Nend_UBRbox_2	1	3	PF02207	0.370
DOC_AGCK_PIF_1	17	22	PF00069	0.460
DOC_CKS1_1	481	486	PF01111	0.364
DOC_CYCLIN_RxL_1	189	200	PF00134	0.483
DOC_CYCLIN_RxL_1	687	698	PF00134	0.443
DOC_CYCLIN_RxL_1	794	807	PF00134	0.544
DOC_CYCLIN_yCln2_LP_2	1520	1526	PF00134	0.483
DOC_CYCLIN_yCln2_LP_2	481	487	PF00134	0.441
DOC_MAPK_gen_1	1017	1023	PF00069	0.346
DOC_MAPK_gen_1	1039	1049	PF00069	0.443
DOC_MAPK_gen_1	116	126	PF00069	0.444
DOC_MAPK_gen_1	1235	1243	PF00069	0.459
DOC_MAPK_gen_1	1285	1292	PF00069	0.348
DOC_MAPK_gen_1	1301	1309	PF00069	0.343
DOC_MAPK_gen_1	1380	1390	PF00069	0.463
DOC_MAPK_gen_1	1470	1478	PF00069	0.344
DOC_MAPK_gen_1	328	337	PF00069	0.443
DOC_MAPK_gen_1	369	378	PF00069	0.392
DOC_MAPK_gen_1	445	453	PF00069	0.377
DOC_MAPK_gen_1	474	480	PF00069	0.324
DOC_MAPK_gen_1	554	561	PF00069	0.460
DOC_MAPK_gen_1	876	884	PF00069	0.353
DOC_MAPK_gen_1	952	960	PF00069	0.339
DOC_MAPK_gen_1	994	1002	PF00069	0.319
DOC_MAPK_HePTP_8	1378	1390	PF00069	0.460
DOC_MAPK_MEF2A_6	1381	1390	PF00069	0.444
DOC_MAPK_MEF2A_6	1470	1478	PF00069	0.344
DOC_MAPK_MEF2A_6	198	205	PF00069	0.443
DOC_MAPK_MEF2A_6	554	561	PF00069	0.444
DOC_MAPK_MEF2A_6	876	884	PF00069	0.383
DOC_MAPK_MEF2A_6	996	1004	PF00069	0.315
DOC_PP1_RVXF_1	1303	1310	PF00149	0.426
DOC_PP1_RVXF_1	1554	1560	PF00149	0.514
DOC_PP1_RVXF_1	235	242	PF00149	0.514
DOC_PP1_RVXF_1	523	530	PF00149	0.514
DOC_PP1_RVXF_1	975	981	PF00149	0.385
DOC_PP2B_LxvP_1	1047	1050	PF13499	0.421
DOC_PP2B_LxvP_1	1520	1523	PF13499	0.483
DOC_PP2B_LxvP_1	1659	1662	PF13499	0.514
DOC_PP4_FxxP_1	1157	1160	PF00568	0.460
DOC_PP4_FxxP_1	1300	1303	PF00568	0.303
DOC_PP4_FxxP_1	154	157	PF00568	0.399
DOC_PP4_FxxP_1	770	773	PF00568	0.338
DOC_USP7_MATH_1	1214	1218	PF00917	0.443
DOC_USP7_MATH_1	1365	1369	PF00917	0.474
DOC_USP7_MATH_1	1441	1445	PF00917	0.388
DOC_USP7_MATH_1	1516	1520	PF00917	0.544
DOC_USP7_MATH_1	1579	1583	PF00917	0.443
DOC_USP7_MATH_1	164	168	PF00917	0.484
DOC_USP7_MATH_1	1660	1664	PF00917	0.544
DOC_USP7_MATH_1	331	335	PF00917	0.483
DOC_USP7_MATH_1	513	517	PF00917	0.443
DOC_USP7_MATH_1	671	675	PF00917	0.443
DOC_USP7_UBL2_3	1165	1169	PF12436	0.443
DOC_USP7_UBL2_3	1456	1460	PF12436	0.487
DOC_USP7_UBL2_3	1583	1587	PF12436	0.514
DOC_USP7_UBL2_3	1629	1633	PF12436	0.483
DOC_USP7_UBL2_3	365	369	PF12436	0.358
DOC_WD40_RPTOR_TOS_1	1309	1314	PF00400	0.181
DOC_WW_Pin1_4	1671	1676	PF00397	0.462
DOC_WW_Pin1_4	1693	1698	PF00397	0.460
DOC_WW_Pin1_4	480	485	PF00397	0.359
DOC_WW_Pin1_4	56	61	PF00397	0.483
DOC_WW_Pin1_4	561	566	PF00397	0.460
DOC_WW_Pin1_4	788	793	PF00397	0.443
LIG_14-3-3_CanoR_1	1208	1214	PF00244	0.443
LIG_14-3-3_CanoR_1	1490	1498	PF00244	0.422
LIG_14-3-3_CanoR_1	1573	1578	PF00244	0.461
LIG_14-3-3_CanoR_1	171	179	PF00244	0.406
LIG_14-3-3_CanoR_1	1757	1765	PF00244	0.357
LIG_14-3-3_CanoR_1	1781	1791	PF00244	0.483
LIG_14-3-3_CanoR_1	288	298	PF00244	0.483
LIG_14-3-3_CanoR_1	933	939	PF00244	0.311
LIG_Actin_WH2_2	1001	1019	PF00022	0.434
LIG_Actin_WH2_2	1186	1203	PF00022	0.443
LIG_Actin_WH2_2	1788	1806	PF00022	0.460
LIG_AP2alpha_2	651	653	PF02296	0.544
LIG_APCC_ABBA_1	1371	1376	PF00400	0.544
LIG_APCC_ABBA_1	1431	1436	PF00400	0.322
LIG_APCC_ABBAyCdc20_2	1370	1376	PF00400	0.488
LIG_BRCT_BRCA1_1	1211	1215	PF00533	0.443
LIG_BRCT_BRCA1_1	1678	1682	PF00533	0.465
LIG_BRCT_BRCA1_1	333	337	PF00533	0.483
LIG_BRCT_BRCA1_1	936	940	PF00533	0.313
LIG_CtBP_PxDLS_1	42	46	PF00389	0.460
LIG_deltaCOP1_diTrp_1	308	314	PF00928	0.442
LIG_deltaCOP1_diTrp_1	323	332	PF00928	0.447
LIG_EH1_1	1471	1479	PF00400	0.442
LIG_EH1_1	198	206	PF00400	0.544
LIG_eIF4E_1	4	10	PF01652	0.436
LIG_eIF4E_1	50	56	PF01652	0.460
LIG_eIF4E_1	823	829	PF01652	0.544
LIG_FHA_1	1095	1101	PF00498	0.500
LIG_FHA_1	1153	1159	PF00498	0.443
LIG_FHA_1	1217	1223	PF00498	0.443
LIG_FHA_1	126	132	PF00498	0.443
LIG_FHA_1	1275	1281	PF00498	0.365
LIG_FHA_1	1315	1321	PF00498	0.366
LIG_FHA_1	1338	1344	PF00498	0.451
LIG_FHA_1	157	163	PF00498	0.431
LIG_FHA_1	1694	1700	PF00498	0.514
LIG_FHA_1	176	182	PF00498	0.364
LIG_FHA_1	1782	1788	PF00498	0.460
LIG_FHA_1	200	206	PF00498	0.443
LIG_FHA_1	211	217	PF00498	0.443
LIG_FHA_1	231	237	PF00498	0.308
LIG_FHA_1	34	40	PF00498	0.443
LIG_FHA_1	346	352	PF00498	0.443
LIG_FHA_1	407	413	PF00498	0.437
LIG_FHA_1	696	702	PF00498	0.420
LIG_FHA_2	1056	1062	PF00498	0.446
LIG_FHA_2	1120	1126	PF00498	0.488
LIG_FHA_2	1161	1167	PF00498	0.429
LIG_FHA_2	1617	1623	PF00498	0.493
LIG_FHA_2	1820	1826	PF00498	0.450
LIG_FHA_2	419	425	PF00498	0.386
LIG_FHA_2	513	519	PF00498	0.434
LIG_FHA_2	749	755	PF00498	0.356
LIG_FHA_2	869	875	PF00498	0.396
LIG_FHA_2	968	974	PF00498	0.378
LIG_FHA_2	985	991	PF00498	0.358
LIG_HCF-1_HBM_1	427	430	PF13415	0.425
LIG_IRF3_LxIS_1	1216	1223	PF10401	0.443
LIG_LIR_Apic_2	1155	1160	PF02991	0.460
LIG_LIR_Apic_2	1419	1423	PF02991	0.514
LIG_LIR_Apic_2	151	157	PF02991	0.395
LIG_LIR_Apic_2	427	433	PF02991	0.361
LIG_LIR_Apic_2	768	773	PF02991	0.440
LIG_LIR_Gen_1	106	115	PF02991	0.488
LIG_LIR_Gen_1	1259	1268	PF02991	0.331
LIG_LIR_Gen_1	1382	1390	PF02991	0.439
LIG_LIR_Gen_1	1514	1524	PF02991	0.514
LIG_LIR_Gen_1	1536	1546	PF02991	0.445
LIG_LIR_Gen_1	1615	1624	PF02991	0.544
LIG_LIR_Gen_1	1674	1685	PF02991	0.460
LIG_LIR_Gen_1	1799	1808	PF02991	0.494
LIG_LIR_Gen_1	329	339	PF02991	0.443
LIG_LIR_Gen_1	578	588	PF02991	0.443
LIG_LIR_Gen_1	622	632	PF02991	0.443
LIG_LIR_Gen_1	654	664	PF02991	0.443
LIG_LIR_Gen_1	712	721	PF02991	0.325
LIG_LIR_Gen_1	780	787	PF02991	0.383
LIG_LIR_Gen_1	921	932	PF02991	0.314
LIG_LIR_Nem_3	103	108	PF02991	0.444
LIG_LIR_Nem_3	1223	1227	PF02991	0.456
LIG_LIR_Nem_3	1259	1263	PF02991	0.326
LIG_LIR_Nem_3	1382	1387	PF02991	0.439
LIG_LIR_Nem_3	1448	1453	PF02991	0.351
LIG_LIR_Nem_3	1499	1504	PF02991	0.507
LIG_LIR_Nem_3	15	20	PF02991	0.443
LIG_LIR_Nem_3	1514	1520	PF02991	0.372
LIG_LIR_Nem_3	1536	1541	PF02991	0.445
LIG_LIR_Nem_3	1558	1562	PF02991	0.497
LIG_LIR_Nem_3	1588	1594	PF02991	0.444
LIG_LIR_Nem_3	1615	1620	PF02991	0.544
LIG_LIR_Nem_3	1674	1680	PF02991	0.460
LIG_LIR_Nem_3	1750	1755	PF02991	0.461
LIG_LIR_Nem_3	1799	1805	PF02991	0.514
LIG_LIR_Nem_3	1836	1840	PF02991	0.398
LIG_LIR_Nem_3	214	220	PF02991	0.445
LIG_LIR_Nem_3	301	305	PF02991	0.449
LIG_LIR_Nem_3	307	313	PF02991	0.438
LIG_LIR_Nem_3	329	335	PF02991	0.453
LIG_LIR_Nem_3	349	355	PF02991	0.308
LIG_LIR_Nem_3	578	584	PF02991	0.443
LIG_LIR_Nem_3	622	627	PF02991	0.443
LIG_LIR_Nem_3	654	660	PF02991	0.443
LIG_LIR_Nem_3	712	718	PF02991	0.328
LIG_LIR_Nem_3	764	770	PF02991	0.446
LIG_LIR_Nem_3	791	796	PF02991	0.489
LIG_LIR_Nem_3	818	823	PF02991	0.514
LIG_LIR_Nem_3	921	927	PF02991	0.320
LIG_LIR_Nem_3	939	945	PF02991	0.238
LIG_LRP6_Inhibitor_1	1627	1633	PF00058	0.135
LIG_LYPXL_yS_3	1072	1075	PF13949	0.514
LIG_NRBOX	192	198	PF00104	0.443
LIG_NRBOX	863	869	PF00104	0.488
LIG_PCNA_PIPBox_1	814	823	PF02747	0.543
LIG_Pex14_1	310	314	PF04695	0.443
LIG_Pex14_2	1513	1517	PF04695	0.483
LIG_Pex14_2	298	302	PF04695	0.443
LIG_PTB_Apo_2	1532	1539	PF02174	0.474
LIG_PTB_Apo_2	618	625	PF02174	0.443
LIG_Rb_pABgroove_1	1734	1742	PF01858	0.460
LIG_REV1ctd_RIR_1	818	828	PF16727	0.443
LIG_SH2_CRK	1172	1176	PF00017	0.544
LIG_SH2_CRK	1420	1424	PF00017	0.486
LIG_SH2_CRK	217	221	PF00017	0.443
LIG_SH2_CRK	65	69	PF00017	0.443
LIG_SH2_CRK	924	928	PF00017	0.319
LIG_SH2_CRK	942	946	PF00017	0.336
LIG_SH2_GRB2like	588	591	PF00017	0.460
LIG_SH2_GRB2like	839	842	PF00017	0.544
LIG_SH2_NCK_1	1118	1122	PF00017	0.488
LIG_SH2_NCK_1	1172	1176	PF00017	0.460
LIG_SH2_NCK_1	1724	1728	PF00017	0.468
LIG_SH2_NCK_1	4	8	PF00017	0.438
LIG_SH2_PTP2	657	660	PF00017	0.443
LIG_SH2_PTP2	715	718	PF00017	0.323
LIG_SH2_SRC	1118	1121	PF00017	0.397
LIG_SH2_SRC	1565	1568	PF00017	0.544
LIG_SH2_SRC	1594	1597	PF00017	0.405
LIG_SH2_SRC	24	27	PF00017	0.483
LIG_SH2_SRC	905	908	PF00017	0.480
LIG_SH2_STAP1	1124	1128	PF00017	0.453
LIG_SH2_STAP1	1374	1378	PF00017	0.461
LIG_SH2_STAP1	1740	1744	PF00017	0.460
LIG_SH2_STAP1	1755	1759	PF00017	0.460
LIG_SH2_STAP1	24	28	PF00017	0.443
LIG_SH2_STAP1	588	592	PF00017	0.460
LIG_SH2_STAP1	839	843	PF00017	0.507
LIG_SH2_STAT3	476	479	PF00017	0.347
LIG_SH2_STAT3	50	53	PF00017	0.460
LIG_SH2_STAT3	910	913	PF00017	0.361
LIG_SH2_STAT3	98	101	PF00017	0.514
LIG_SH2_STAT5	1080	1083	PF00017	0.442
LIG_SH2_STAT5	1099	1102	PF00017	0.349
LIG_SH2_STAT5	1323	1326	PF00017	0.460
LIG_SH2_STAT5	1453	1456	PF00017	0.360
LIG_SH2_STAT5	1504	1507	PF00017	0.514
LIG_SH2_STAT5	1560	1563	PF00017	0.523
LIG_SH2_STAT5	1565	1568	PF00017	0.502
LIG_SH2_STAT5	1594	1597	PF00017	0.444
LIG_SH2_STAT5	313	316	PF00017	0.460
LIG_SH2_STAT5	350	353	PF00017	0.447
LIG_SH2_STAT5	355	358	PF00017	0.340
LIG_SH2_STAT5	430	433	PF00017	0.353
LIG_SH2_STAT5	537	540	PF00017	0.460
LIG_SH2_STAT5	657	660	PF00017	0.443
LIG_SH2_STAT5	715	718	PF00017	0.323
LIG_SH2_STAT5	767	770	PF00017	0.445
LIG_SH2_STAT5	80	83	PF00017	0.478
LIG_SH2_STAT5	905	908	PF00017	0.339
LIG_SH2_STAT5	979	982	PF00017	0.360
LIG_SH2_STAT5	98	101	PF00017	0.352
LIG_SH3_3	1046	1052	PF00018	0.443
LIG_SH3_3	1067	1073	PF00018	0.443
LIG_SH3_3	1181	1187	PF00018	0.443
LIG_SH3_3	1805	1811	PF00018	0.378
LIG_SH3_3	1826	1832	PF00018	0.448
LIG_SH3_3	223	229	PF00018	0.443
LIG_SH3_3	36	42	PF00018	0.443
LIG_SH3_3	609	615	PF00018	0.443
LIG_SH3_3	715	721	PF00018	0.321
LIG_SH3_5	711	715	PF00018	0.337
LIG_SUMO_SIM_anti_2	1125	1130	PF11976	0.443
LIG_SUMO_SIM_anti_2	1180	1186	PF11976	0.437
LIG_SUMO_SIM_anti_2	200	205	PF11976	0.444
LIG_SUMO_SIM_anti_2	483	489	PF11976	0.450
LIG_SUMO_SIM_anti_2	984	993	PF11976	0.381
LIG_SUMO_SIM_par_1	1109	1115	PF11976	0.443
LIG_SUMO_SIM_par_1	1522	1528	PF11976	0.443
LIG_SUMO_SIM_par_1	1788	1794	PF11976	0.449
LIG_SUMO_SIM_par_1	180	185	PF11976	0.347
LIG_SUMO_SIM_par_1	432	437	PF11976	0.438
LIG_SUMO_SIM_par_1	486	493	PF11976	0.355
LIG_SUMO_SIM_par_1	53	59	PF11976	0.460
LIG_SUMO_SIM_par_1	984	993	PF11976	0.498
LIG_TRAF2_1	1822	1825	PF00917	0.480
LIG_TRAF2_1	516	519	PF00917	0.483
LIG_TRAF2_1	751	754	PF00917	0.339
LIG_TRAF2_1	807	810	PF00917	0.491
LIG_TRAF2_2	1159	1164	PF00917	0.460
LIG_TRFH_1	648	652	PF08558	0.443
LIG_TYR_ITIM	1070	1075	PF00017	0.514
LIG_TYR_ITIM	579	584	PF00017	0.443
LIG_UBA3_1	1800	1804	PF00899	0.483
LIG_UBA3_1	181	189	PF00899	0.298
LIG_UBA3_1	851	855	PF00899	0.457
LIG_WRC_WIRS_1	1257	1262	PF05994	0.330
LIG_WW_1	1408	1411	PF00397	0.468
MOD_CDK_SPxK_1	788	794	PF00069	0.443
MOD_CK1_1	1056	1062	PF00069	0.505
MOD_CK1_1	1104	1110	PF00069	0.431
MOD_CK1_1	1209	1215	PF00069	0.443
MOD_CK1_1	1223	1229	PF00069	0.457
MOD_CK1_1	1256	1262	PF00069	0.356
MOD_CK1_1	1555	1561	PF00069	0.514
MOD_CK1_1	167	173	PF00069	0.446
MOD_CK1_1	1785	1791	PF00069	0.544
MOD_CK1_1	46	52	PF00069	0.488
MOD_CK1_1	667	673	PF00069	0.443
MOD_CK1_1	674	680	PF00069	0.443
MOD_CK1_1	984	990	PF00069	0.355
MOD_CK2_1	1055	1061	PF00069	0.468
MOD_CK2_1	1273	1279	PF00069	0.362
MOD_CK2_1	1312	1318	PF00069	0.419
MOD_CK2_1	1440	1446	PF00069	0.425
MOD_CK2_1	1542	1548	PF00069	0.514
MOD_CK2_1	1772	1778	PF00069	0.469
MOD_CK2_1	1819	1825	PF00069	0.451
MOD_CK2_1	398	404	PF00069	0.534
MOD_CK2_1	418	424	PF00069	0.205
MOD_CK2_1	512	518	PF00069	0.443
MOD_CK2_1	617	623	PF00069	0.443
MOD_CK2_1	738	744	PF00069	0.378
MOD_CK2_1	748	754	PF00069	0.337
MOD_CK2_1	804	810	PF00069	0.460
MOD_GlcNHglycan	1018	1021	PF01048	0.462
MOD_GlcNHglycan	1055	1058	PF01048	0.314
MOD_GlcNHglycan	1082	1085	PF01048	0.233
MOD_GlcNHglycan	1106	1109	PF01048	0.256
MOD_GlcNHglycan	1150	1153	PF01048	0.243
MOD_GlcNHglycan	1229	1232	PF01048	0.327
MOD_GlcNHglycan	1361	1364	PF01048	0.274
MOD_GlcNHglycan	1535	1538	PF01048	0.331
MOD_GlcNHglycan	1544	1547	PF01048	0.288
MOD_GlcNHglycan	1683	1686	PF01048	0.258
MOD_GlcNHglycan	1745	1749	PF01048	0.264
MOD_GlcNHglycan	1774	1777	PF01048	0.277
MOD_GlcNHglycan	1786	1790	PF01048	0.260
MOD_GlcNHglycan	392	396	PF01048	0.365
MOD_GlcNHglycan	510	513	PF01048	0.269
MOD_GlcNHglycan	543	546	PF01048	0.243
MOD_GlcNHglycan	628	631	PF01048	0.260
MOD_GlcNHglycan	669	672	PF01048	0.243
MOD_GlcNHglycan	806	809	PF01048	0.344
MOD_GlcNHglycan	90	93	PF01048	0.243
MOD_GSK3_1	1012	1019	PF00069	0.484
MOD_GSK3_1	1076	1083	PF00069	0.441
MOD_GSK3_1	1148	1155	PF00069	0.437
MOD_GSK3_1	1160	1167	PF00069	0.413
MOD_GSK3_1	1216	1223	PF00069	0.443
MOD_GSK3_1	1355	1362	PF00069	0.463
MOD_GSK3_1	1642	1649	PF00069	0.488
MOD_GSK3_1	1740	1747	PF00069	0.471
MOD_GSK3_1	1753	1760	PF00069	0.470
MOD_GSK3_1	1766	1773	PF00069	0.479
MOD_GSK3_1	1781	1788	PF00069	0.443
MOD_GSK3_1	231	238	PF00069	0.514
MOD_GSK3_1	314	321	PF00069	0.538
MOD_GSK3_1	508	515	PF00069	0.416
MOD_GSK3_1	613	620	PF00069	0.443
MOD_GSK3_1	667	674	PF00069	0.443
MOD_GSK3_1	695	702	PF00069	0.419
MOD_GSK3_1	734	741	PF00069	0.369
MOD_GSK3_1	744	751	PF00069	0.343
MOD_GSK3_1	829	836	PF00069	0.550
MOD_N-GLC_1	1481	1486	PF02516	0.404
MOD_N-GLC_1	1496	1501	PF02516	0.260
MOD_N-GLC_1	1833	1838	PF02516	0.406
MOD_N-GLC_1	868	873	PF02516	0.486
MOD_N-GLC_2	1464	1466	PF02516	0.382
MOD_NEK2_1	1012	1017	PF00069	0.479
MOD_NEK2_1	107	112	PF00069	0.428
MOD_NEK2_1	1082	1087	PF00069	0.372
MOD_NEK2_1	1220	1225	PF00069	0.443
MOD_NEK2_1	125	130	PF00069	0.504
MOD_NEK2_1	1476	1481	PF00069	0.362
MOD_NEK2_1	1496	1501	PF00069	0.308
MOD_NEK2_1	1744	1749	PF00069	0.379
MOD_NEK2_1	1803	1808	PF00069	0.377
MOD_NEK2_1	220	225	PF00069	0.443
MOD_NEK2_1	231	236	PF00069	0.443
MOD_NEK2_1	391	396	PF00069	0.361
MOD_NEK2_1	497	502	PF00069	0.544
MOD_NEK2_1	55	60	PF00069	0.443
MOD_NEK2_1	569	574	PF00069	0.443
MOD_NEK2_1	626	631	PF00069	0.443
MOD_NEK2_1	666	671	PF00069	0.443
MOD_NEK2_1	695	700	PF00069	0.456
MOD_NEK2_1	738	743	PF00069	0.390
MOD_NEK2_1	75	80	PF00069	0.308
MOD_NEK2_1	867	872	PF00069	0.518
MOD_NEK2_1	906	911	PF00069	0.339
MOD_NEK2_2	1152	1157	PF00069	0.460
MOD_NEK2_2	1253	1258	PF00069	0.364
MOD_NEK2_2	175	180	PF00069	0.427
MOD_NEK2_2	232	237	PF00069	0.514
MOD_NEK2_2	398	403	PF00069	0.494
MOD_NEK2_2	834	839	PF00069	0.544
MOD_PIKK_1	1312	1318	PF00454	0.461
MOD_PIKK_1	1489	1495	PF00454	0.434
MOD_PIKK_1	1757	1763	PF00454	0.493
MOD_PIKK_1	1770	1776	PF00454	0.409
MOD_PIKK_1	290	296	PF00454	0.443
MOD_PIKK_1	393	399	PF00454	0.382
MOD_PIKK_1	613	619	PF00454	0.443
MOD_PK_1	1573	1579	PF00069	0.544
MOD_PK_1	1669	1675	PF00069	0.419
MOD_PK_1	628	634	PF00069	0.460
MOD_PKA_1	1400	1406	PF00069	0.460
MOD_PKA_1	1573	1579	PF00069	0.488
MOD_PKA_2	1076	1082	PF00069	0.443
MOD_PKA_2	1207	1213	PF00069	0.443
MOD_PKA_2	1400	1406	PF00069	0.460
MOD_PKA_2	1489	1495	PF00069	0.434
MOD_PKA_2	1573	1579	PF00069	0.527
MOD_PKA_2	170	176	PF00069	0.418
MOD_PKA_2	497	503	PF00069	0.544
MOD_PKA_2	664	670	PF00069	0.443
MOD_PKA_2	829	835	PF00069	0.548
MOD_PKA_2	841	847	PF00069	0.380
MOD_PKB_1	1571	1579	PF00069	0.483
MOD_Plk_1	1094	1100	PF00069	0.476
MOD_Plk_1	1101	1107	PF00069	0.442
MOD_Plk_1	1152	1158	PF00069	0.443
MOD_Plk_1	1496	1502	PF00069	0.483
MOD_Plk_1	1669	1675	PF00069	0.419
MOD_Plk_1	1740	1746	PF00069	0.514
MOD_Plk_1	199	205	PF00069	0.443
MOD_Plk_1	24	30	PF00069	0.443
MOD_Plk_1	569	575	PF00069	0.443
MOD_Plk_1	984	990	PF00069	0.355
MOD_Plk_2-3	1119	1125	PF00069	0.488
MOD_Plk_2-3	1616	1622	PF00069	0.514
MOD_Plk_2-3	981	987	PF00069	0.347
MOD_Plk_4	1076	1082	PF00069	0.454
MOD_Plk_4	1101	1107	PF00069	0.433
MOD_Plk_4	1152	1158	PF00069	0.443
MOD_Plk_4	1223	1229	PF00069	0.503
MOD_Plk_4	1253	1259	PF00069	0.362
MOD_Plk_4	1426	1432	PF00069	0.428
MOD_Plk_4	1555	1561	PF00069	0.514
MOD_Plk_4	1573	1579	PF00069	0.338
MOD_Plk_4	1647	1653	PF00069	0.514
MOD_Plk_4	1660	1666	PF00069	0.514
MOD_Plk_4	199	205	PF00069	0.444
MOD_Plk_4	406	412	PF00069	0.404
MOD_Plk_4	483	489	PF00069	0.450
MOD_Plk_4	497	503	PF00069	0.514
MOD_Plk_4	607	613	PF00069	0.443
MOD_Plk_4	734	740	PF00069	0.356
MOD_Plk_4	834	840	PF00069	0.494
MOD_Plk_4	984	990	PF00069	0.355
MOD_ProDKin_1	1671	1677	PF00069	0.462
MOD_ProDKin_1	1693	1699	PF00069	0.460
MOD_ProDKin_1	480	486	PF00069	0.361
MOD_ProDKin_1	56	62	PF00069	0.483
MOD_ProDKin_1	561	567	PF00069	0.460
MOD_ProDKin_1	788	794	PF00069	0.443
MOD_SUMO_for_1	1379	1382	PF00179	0.500
MOD_SUMO_for_1	5	8	PF00179	0.477
TRG_DiLeu_BaEn_1	1350	1355	PF01217	0.335
TRG_DiLeu_BaEn_1	1382	1387	PF01217	0.464
TRG_DiLeu_BaEn_2	1777	1783	PF01217	0.484
TRG_DiLeu_BaEn_3	733	739	PF01217	0.417
TRG_DiLeu_BaLyEn_6	1420	1425	PF01217	0.514
TRG_DiLeu_BaLyEn_6	1694	1699	PF01217	0.514
TRG_DiLeu_BaLyEn_6	883	888	PF01217	0.444
TRG_ENDOCYTIC_2	1072	1075	PF00928	0.514
TRG_ENDOCYTIC_2	108	111	PF00928	0.444
TRG_ENDOCYTIC_2	1172	1175	PF00928	0.544
TRG_ENDOCYTIC_2	1458	1461	PF00928	0.338
TRG_ENDOCYTIC_2	217	220	PF00928	0.443
TRG_ENDOCYTIC_2	581	584	PF00928	0.443
TRG_ENDOCYTIC_2	657	660	PF00928	0.443
TRG_ENDOCYTIC_2	715	718	PF00928	0.323
TRG_ENDOCYTIC_2	767	770	PF00928	0.445
TRG_ENDOCYTIC_2	793	796	PF00928	0.493
TRG_ENDOCYTIC_2	924	927	PF00928	0.320
TRG_ENDOCYTIC_2	942	945	PF00928	0.336
TRG_ER_diArg_1	1328	1330	PF00400	0.544
TRG_ER_diArg_1	1399	1401	PF00400	0.457
TRG_ER_diArg_1	1413	1415	PF00400	0.414
TRG_ER_diArg_1	1570	1573	PF00400	0.514
TRG_ER_diArg_1	1814	1816	PF00400	0.499
TRG_ER_diArg_1	875	878	PF00400	0.359
TRG_ER_diArg_1	951	953	PF00400	0.313
TRG_NES_CRM1_1	137	151	PF08389	0.483
TRG_NES_CRM1_1	1518	1532	PF08389	0.543
TRG_NES_CRM1_1	423	437	PF08389	0.358
TRG_NES_CRM1_1	813	826	PF08389	0.488
TRG_NLS_MonoExtN_4	1242	1248	PF00514	0.408
TRG_Pf-PMV_PEXEL_1	1098	1102	PF00026	0.260
TRG_Pf-PMV_PEXEL_1	1414	1419	PF00026	0.243
TRG_Pf-PMV_PEXEL_1	160	165	PF00026	0.445
TRG_Pf-PMV_PEXEL_1	1781	1786	PF00026	0.260
TRG_Pf-PMV_PEXEL_1	180	185	PF00026	0.153
TRG_Pf-PMV_PEXEL_1	400	404	PF00026	0.416
TRG_Pf-PMV_PEXEL_1	494	499	PF00026	0.314
TRG_Pf-PMV_PEXEL_1	585	589	PF00026	0.243
TRG_Pf-PMV_PEXEL_1	692	696	PF00026	0.243
TRG_Pf-PMV_PEXEL_1	800	804	PF00026	0.283
TRG_Pf-PMV_PEXEL_1	862	866	PF00026	0.314

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I157	Leptomonas seymouri	87%	100%
A0A1X0NNV1	Trypanosomatidae	76%	100%
A0A3S5H6X3	Leishmania donovani	98%	100%
A0A422MVX7	Trypanosoma rangeli	75%	100%
A4H8I3	Leishmania braziliensis	94%	100%
A4HWV8	Leishmania infantum	98%	100%
B2RQC6	Mus musculus	49%	83%
C9ZPQ9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	73%	100%
O93937	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	49%	81%
P05990	Drosophila melanogaster	50%	83%
P07259	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	48%	83%
P07756	Rattus norvegicus	48%	100%
P08955	Mesocricetus auratus	49%	83%
P20054	Dictyostelium discoideum	49%	83%
P27708	Homo sapiens	49%	83%
P31327	Homo sapiens	47%	100%
Q09794	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	48%	82%
Q18990	Caenorhabditis elegans	49%	84%
Q4QEW0	Leishmania major	98%	100%
Q8C196	Mus musculus	48%	100%
Q91293	Lithobates catesbeianus	48%	100%
Q91437	Squalus acanthias	49%	82%