Putative fucose kinase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Download

Quick info

Protein:

Gene product:

Protein of unknown function (DUF2946), putative

Species:

Leishmania mexicana

UniProt:

E9AQK2_LEIMU

TriTrypDb:

Length:

359

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQK2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQK2

Function

Biological processes
Term	Name	Level	Count
GO:0006793	phosphorus metabolic process	3	2
GO:0006796	phosphate-containing compound metabolic process	4	2
GO:0008152	metabolic process	1	2
GO:0009987	cellular process	1	2
GO:0016310	phosphorylation	5	2
GO:0044237	cellular metabolic process	2	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	2
GO:0003824	catalytic activity	1	2
GO:0005488	binding	1	2
GO:0016301	kinase activity	4	2
GO:0016740	transferase activity	2	2
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	2
GO:0036094	small molecule binding	2	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901265	nucleoside phosphate binding	3	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	313	317	PF00656	0.673
CLV_NRD_NRD_1	107	109	PF00675	0.600
CLV_NRD_NRD_1	20	22	PF00675	0.713
CLV_NRD_NRD_1	226	228	PF00675	0.600
CLV_NRD_NRD_1	253	255	PF00675	0.600
CLV_NRD_NRD_1	337	339	PF00675	0.727
CLV_PCSK_KEX2_1	107	109	PF00082	0.600
CLV_PCSK_KEX2_1	20	22	PF00082	0.713
CLV_PCSK_KEX2_1	225	227	PF00082	0.600
CLV_PCSK_KEX2_1	337	339	PF00082	0.727
CLV_PCSK_SKI1_1	117	121	PF00082	0.600
CLV_PCSK_SKI1_1	135	139	PF00082	0.284
CLV_PCSK_SKI1_1	170	174	PF00082	0.600
CLV_PCSK_SKI1_1	20	24	PF00082	0.688
CLV_PCSK_SKI1_1	83	87	PF00082	0.701
DEG_APCC_DBOX_1	169	177	PF00400	0.600
DEG_Nend_UBRbox_3	1	3	PF02207	0.687
DEG_ODPH_VHL_1	176	189	PF01847	0.600
DOC_CYCLIN_RxL_1	129	140	PF00134	0.600
DOC_CYCLIN_RxL_1	205	213	PF00134	0.600
DOC_MAPK_MEF2A_6	232	241	PF00069	0.600
DOC_PP2B_LxvP_1	120	123	PF13499	0.600
DOC_PP4_FxxP_1	7	10	PF00568	0.633
DOC_USP7_MATH_1	172	176	PF00917	0.600
DOC_USP7_MATH_1	292	296	PF00917	0.600
DOC_USP7_MATH_1	341	345	PF00917	0.788
DOC_USP7_MATH_1	81	85	PF00917	0.713
LIG_14-3-3_CanoR_1	135	145	PF00244	0.600
LIG_14-3-3_CanoR_1	232	236	PF00244	0.600
LIG_14-3-3_CanoR_1	275	283	PF00244	0.600
LIG_14-3-3_CanoR_1	326	335	PF00244	0.686
LIG_Actin_WH2_2	300	317	PF00022	0.681
LIG_APCC_ABBA_1	142	147	PF00400	0.600
LIG_APCC_ABBA_1	176	181	PF00400	0.600
LIG_BIR_III_4	168	172	PF00653	0.600
LIG_BIR_III_4	265	269	PF00653	0.600
LIG_BRCT_BRCA1_1	3	7	PF00533	0.632
LIG_EVH1_1	120	124	PF00568	0.600
LIG_FHA_1	60	66	PF00498	0.641
LIG_FHA_2	10	16	PF00498	0.687
LIG_FHA_2	202	208	PF00498	0.600
LIG_FHA_2	279	285	PF00498	0.600
LIG_LIR_Apic_2	344	350	PF02991	0.813
LIG_LIR_Apic_2	4	10	PF02991	0.632
LIG_LIR_Gen_1	284	293	PF02991	0.600
LIG_LIR_Gen_1	87	92	PF02991	0.674
LIG_LIR_Nem_3	281	286	PF02991	0.600
LIG_LIR_Nem_3	316	322	PF02991	0.660
LIG_LIR_Nem_3	87	91	PF02991	0.669
LIG_LYPXL_SIV_4	111	119	PF13949	0.600
LIG_MYND_1	174	178	PF01753	0.600
LIG_Pex14_1	347	351	PF04695	0.814
LIG_SH2_CRK	112	116	PF00017	0.600
LIG_SH2_NCK_1	112	116	PF00017	0.600
LIG_SH2_STAT3	214	217	PF00017	0.600
LIG_SH2_STAT5	70	73	PF00017	0.685
LIG_SH3_2	121	126	PF14604	0.600
LIG_SH3_3	118	124	PF00018	0.600
LIG_SH3_3	351	357	PF00018	0.834
LIG_SH3_3	37	43	PF00018	0.811
LIG_SUMO_SIM_par_1	207	213	PF11976	0.600
LIG_SUMO_SIM_par_1	310	316	PF11976	0.658
MOD_CK1_1	131	137	PF00069	0.600
MOD_CK1_1	55	61	PF00069	0.672
MOD_CK1_1	84	90	PF00069	0.681
MOD_CK2_1	201	207	PF00069	0.600
MOD_CK2_1	217	223	PF00069	0.319
MOD_CK2_1	27	33	PF00069	0.434
MOD_CK2_1	307	313	PF00069	0.648
MOD_CK2_1	9	15	PF00069	0.675
MOD_GlcNHglycan	290	293	PF01048	0.600
MOD_GlcNHglycan	298	301	PF01048	0.459
MOD_GlcNHglycan	329	332	PF01048	0.690
MOD_GlcNHglycan	57	60	PF01048	0.662
MOD_GSK3_1	1	8	PF00069	0.651
MOD_GSK3_1	133	140	PF00069	0.600
MOD_GSK3_1	274	281	PF00069	0.600
MOD_GSK3_1	284	291	PF00069	0.425
MOD_GSK3_1	292	299	PF00069	0.284
MOD_GSK3_1	55	62	PF00069	0.668
MOD_N-GLC_1	1	6	PF02516	0.659
MOD_NEK2_1	1	6	PF00069	0.659
MOD_NEK2_1	133	138	PF00069	0.600
MOD_NEK2_1	148	153	PF00069	0.337
MOD_NEK2_1	307	312	PF00069	0.647
MOD_NEK2_2	59	64	PF00069	0.643
MOD_PIKK_1	128	134	PF00454	0.600
MOD_PIKK_1	137	143	PF00454	0.442
MOD_PKA_2	128	134	PF00069	0.600
MOD_PKA_2	231	237	PF00069	0.600
MOD_PKA_2	274	280	PF00069	0.600
MOD_Plk_1	1	7	PF00069	0.654
MOD_Plk_1	52	58	PF00069	0.722
MOD_Plk_4	1	7	PF00069	0.654
MOD_Plk_4	231	237	PF00069	0.600
MOD_Plk_4	307	313	PF00069	0.648
MOD_Plk_4	341	347	PF00069	0.795
MOD_Plk_4	81	87	PF00069	0.709
MOD_SUMO_rev_2	50	56	PF00179	0.727
TRG_DiLeu_BaLyEn_6	18	23	PF01217	0.686
TRG_ENDOCYTIC_2	112	115	PF00928	0.600
TRG_ENDOCYTIC_2	145	148	PF00928	0.600
TRG_ENDOCYTIC_2	286	289	PF00928	0.600
TRG_ER_diArg_1	107	109	PF00400	0.600
TRG_ER_diArg_1	20	22	PF00400	0.713
TRG_ER_diArg_1	224	227	PF00400	0.600
TRG_Pf-PMV_PEXEL_1	11	15	PF00026	0.690
TRG_Pf-PMV_PEXEL_1	20	25	PF00026	0.539
TRG_Pf-PMV_PEXEL_1	208	213	PF00026	0.600