XRN_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

XRN 5'-3' exonuclease N-terminus, putative

Species:

Leishmania mexicana

UniProt:

E9AQJ6_LEIMU

TriTrypDb:

LmxM.16.0390

Length:

978

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AQJ6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQJ6

Function

Biological processes
Term	Name	Level	Count
GO:0000956	nuclear-transcribed mRNA catabolic process	7	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006401	RNA catabolic process	5	1
GO:0006402	mRNA catabolic process	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009056	catabolic process	2	1
GO:0009057	macromolecule catabolic process	4	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0009987	cellular process	1	1
GO:0010468	regulation of gene expression	5	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0010629	negative regulation of gene expression	6	1
GO:0016070	RNA metabolic process	5	1
GO:0016071	mRNA metabolic process	6	1
GO:0019222	regulation of metabolic process	3	1
GO:0019439	aromatic compound catabolic process	4	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034655	nucleobase-containing compound catabolic process	4	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044248	cellular catabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044265	obsolete cellular macromolecule catabolic process	4	1
GO:0044270	cellular nitrogen compound catabolic process	4	1
GO:0046483	heterocycle metabolic process	3	1
GO:0046700	heterocycle catabolic process	4	1
GO:0048519	negative regulation of biological process	3	1
GO:0050789	regulation of biological process	2	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1901361	organic cyclic compound catabolic process	4	1
GO:1901575	organic substance catabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	10
GO:0003824	catalytic activity	1	10
GO:0004518	nuclease activity	4	10
GO:0004527	exonuclease activity	5	10
GO:0005488	binding	1	10
GO:0016787	hydrolase activity	2	10
GO:0016788	hydrolase activity, acting on ester bonds	3	10
GO:0097159	organic cyclic compound binding	2	10
GO:1901363	heterocyclic compound binding	2	10
GO:0003723	RNA binding	4	1
GO:0004532	RNA exonuclease activity	5	1
GO:0004534	5'-3' RNA exonuclease activity	7	1
GO:0004540	RNA nuclease activity	4	1
GO:0008409	5'-3' exonuclease activity	6	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	1
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	6	1
GO:0140098	catalytic activity, acting on RNA	3	1
GO:0140640	catalytic activity, acting on a nucleic acid	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	282	286	PF00656	0.432
CLV_C14_Caspase3-7	47	51	PF00656	0.629
CLV_C14_Caspase3-7	933	937	PF00656	0.525
CLV_NRD_NRD_1	174	176	PF00675	0.257
CLV_NRD_NRD_1	220	222	PF00675	0.316
CLV_NRD_NRD_1	271	273	PF00675	0.608
CLV_NRD_NRD_1	279	281	PF00675	0.714
CLV_NRD_NRD_1	34	36	PF00675	0.613
CLV_NRD_NRD_1	395	397	PF00675	0.440
CLV_NRD_NRD_1	586	588	PF00675	0.518
CLV_NRD_NRD_1	6	8	PF00675	0.357
CLV_NRD_NRD_1	727	729	PF00675	0.706
CLV_NRD_NRD_1	744	746	PF00675	0.631
CLV_NRD_NRD_1	76	78	PF00675	0.634
CLV_NRD_NRD_1	775	777	PF00675	0.504
CLV_NRD_NRD_1	779	781	PF00675	0.486
CLV_NRD_NRD_1	800	802	PF00675	0.616
CLV_NRD_NRD_1	864	866	PF00675	0.592
CLV_NRD_NRD_1	891	893	PF00675	0.789
CLV_NRD_NRD_1	924	926	PF00675	0.780
CLV_NRD_NRD_1	927	929	PF00675	0.765
CLV_NRD_NRD_1	952	954	PF00675	0.605
CLV_NRD_NRD_1	976	978	PF00675	0.730
CLV_PCSK_FUR_1	170	174	PF00082	0.260
CLV_PCSK_FUR_1	269	273	PF00082	0.534
CLV_PCSK_FUR_1	925	929	PF00082	0.612
CLV_PCSK_FUR_1	950	954	PF00082	0.597
CLV_PCSK_KEX2_1	128	130	PF00082	0.209
CLV_PCSK_KEX2_1	172	174	PF00082	0.259
CLV_PCSK_KEX2_1	220	222	PF00082	0.320
CLV_PCSK_KEX2_1	271	273	PF00082	0.608
CLV_PCSK_KEX2_1	279	281	PF00082	0.714
CLV_PCSK_KEX2_1	33	35	PF00082	0.612
CLV_PCSK_KEX2_1	395	397	PF00082	0.350
CLV_PCSK_KEX2_1	585	587	PF00082	0.483
CLV_PCSK_KEX2_1	727	729	PF00082	0.674
CLV_PCSK_KEX2_1	76	78	PF00082	0.629
CLV_PCSK_KEX2_1	775	777	PF00082	0.504
CLV_PCSK_KEX2_1	779	781	PF00082	0.486
CLV_PCSK_KEX2_1	926	928	PF00082	0.707
CLV_PCSK_KEX2_1	949	951	PF00082	0.608
CLV_PCSK_KEX2_1	952	954	PF00082	0.607
CLV_PCSK_KEX2_1	974	976	PF00082	0.713
CLV_PCSK_PC1ET2_1	128	130	PF00082	0.209
CLV_PCSK_PC1ET2_1	33	35	PF00082	0.568
CLV_PCSK_PC1ET2_1	926	928	PF00082	0.677
CLV_PCSK_PC1ET2_1	949	951	PF00082	0.575
CLV_PCSK_PC1ET2_1	974	976	PF00082	0.713
CLV_PCSK_PC7_1	170	176	PF00082	0.185
CLV_PCSK_PC7_1	216	222	PF00082	0.315
CLV_PCSK_PC7_1	72	78	PF00082	0.648
CLV_PCSK_PC7_1	775	781	PF00082	0.528
CLV_PCSK_SKI1_1	216	220	PF00082	0.265
CLV_PCSK_SKI1_1	345	349	PF00082	0.510
CLV_PCSK_SKI1_1	550	554	PF00082	0.447
CLV_PCSK_SKI1_1	571	575	PF00082	0.399
CLV_PCSK_SKI1_1	685	689	PF00082	0.672
CLV_PCSK_SKI1_1	77	81	PF00082	0.695
CLV_PCSK_SKI1_1	793	797	PF00082	0.518
CLV_PCSK_SKI1_1	820	824	PF00082	0.458
CLV_PCSK_SKI1_1	867	871	PF00082	0.708
CLV_PCSK_SKI1_1	893	897	PF00082	0.721
DEG_SCF_FBW7_1	501	507	PF00400	0.312
DEG_SCF_FBW7_1	965	972	PF00400	0.481
DEG_SPOP_SBC_1	705	709	PF00917	0.485
DEG_SPOP_SBC_1	78	82	PF00917	0.690
DOC_ANK_TNKS_1	34	41	PF00023	0.630
DOC_CDC14_PxL_1	623	631	PF14671	0.434
DOC_CKS1_1	501	506	PF01111	0.337
DOC_CKS1_1	769	774	PF01111	0.548
DOC_CKS1_1	966	971	PF01111	0.616
DOC_CYCLIN_yCln2_LP_2	624	630	PF00134	0.434
DOC_MAPK_gen_1	170	178	PF00069	0.465
DOC_MAPK_gen_1	220	227	PF00069	0.520
DOC_MAPK_gen_1	297	306	PF00069	0.427
DOC_MAPK_gen_1	550	558	PF00069	0.439
DOC_MAPK_MEF2A_6	150	157	PF00069	0.483
DOC_MAPK_MEF2A_6	368	376	PF00069	0.306
DOC_MAPK_RevD_3	161	175	PF00069	0.530
DOC_MAPK_RevD_3	878	893	PF00069	0.468
DOC_PP1_RVXF_1	240	247	PF00149	0.518
DOC_PP1_RVXF_1	366	372	PF00149	0.293
DOC_PP1_RVXF_1	631	638	PF00149	0.407
DOC_PP1_SILK_1	533	538	PF00149	0.497
DOC_PP2B_LxvP_1	19	22	PF13499	0.480
DOC_PP2B_LxvP_1	624	627	PF13499	0.418
DOC_PP2B_PxIxI_1	364	370	PF00149	0.388
DOC_PP4_FxxP_1	157	160	PF00568	0.530
DOC_PP4_FxxP_1	573	576	PF00568	0.392
DOC_PP4_FxxP_1	637	640	PF00568	0.363
DOC_PP4_FxxP_1	769	772	PF00568	0.546
DOC_PP4_MxPP_1	85	88	PF00568	0.465
DOC_USP7_MATH_1	149	153	PF00917	0.480
DOC_USP7_MATH_1	205	209	PF00917	0.515
DOC_USP7_MATH_1	248	252	PF00917	0.454
DOC_USP7_MATH_1	531	535	PF00917	0.408
DOC_USP7_MATH_1	58	62	PF00917	0.460
DOC_USP7_MATH_1	720	724	PF00917	0.726
DOC_USP7_MATH_1	78	82	PF00917	0.694
DOC_USP7_MATH_1	887	891	PF00917	0.523
DOC_USP7_MATH_1	929	933	PF00917	0.715
DOC_USP7_MATH_1	95	99	PF00917	0.412
DOC_USP7_UBL2_3	866	870	PF12436	0.653
DOC_WW_Pin1_4	258	263	PF00397	0.654
DOC_WW_Pin1_4	327	332	PF00397	0.405
DOC_WW_Pin1_4	354	359	PF00397	0.518
DOC_WW_Pin1_4	408	413	PF00397	0.409
DOC_WW_Pin1_4	500	505	PF00397	0.346
DOC_WW_Pin1_4	572	577	PF00397	0.478
DOC_WW_Pin1_4	610	615	PF00397	0.302
DOC_WW_Pin1_4	691	696	PF00397	0.694
DOC_WW_Pin1_4	768	773	PF00397	0.560
DOC_WW_Pin1_4	825	830	PF00397	0.538
DOC_WW_Pin1_4	83	88	PF00397	0.600
DOC_WW_Pin1_4	965	970	PF00397	0.611
LIG_14-3-3_CanoR_1	140	149	PF00244	0.490
LIG_14-3-3_CanoR_1	150	154	PF00244	0.490
LIG_14-3-3_CanoR_1	173	179	PF00244	0.490
LIG_14-3-3_CanoR_1	338	346	PF00244	0.442
LIG_14-3-3_CanoR_1	395	401	PF00244	0.320
LIG_14-3-3_CanoR_1	571	576	PF00244	0.509
LIG_14-3-3_CanoR_1	595	605	PF00244	0.429
LIG_14-3-3_CanoR_1	680	689	PF00244	0.727
LIG_14-3-3_CanoR_1	745	752	PF00244	0.575
LIG_14-3-3_CanoR_1	76	85	PF00244	0.700
LIG_14-3-3_CanoR_1	806	815	PF00244	0.527
LIG_Actin_WH2_2	332	350	PF00022	0.405
LIG_Actin_WH2_2	777	795	PF00022	0.608
LIG_BIR_III_2	826	830	PF00653	0.525
LIG_BRCT_BRCA1_1	153	157	PF00533	0.530
LIG_Clathr_ClatBox_1	197	201	PF01394	0.447
LIG_eIF4E_1	404	410	PF01652	0.466
LIG_FHA_1	14	20	PF00498	0.403
LIG_FHA_1	142	148	PF00498	0.455
LIG_FHA_1	166	172	PF00498	0.493
LIG_FHA_1	179	185	PF00498	0.465
LIG_FHA_1	187	193	PF00498	0.530
LIG_FHA_1	301	307	PF00498	0.357
LIG_FHA_1	543	549	PF00498	0.485
LIG_FHA_1	572	578	PF00498	0.391
LIG_FHA_1	630	636	PF00498	0.541
LIG_FHA_1	757	763	PF00498	0.443
LIG_FHA_1	810	816	PF00498	0.513
LIG_FHA_1	917	923	PF00498	0.580
LIG_FHA_2	259	265	PF00498	0.710
LIG_FHA_2	351	357	PF00498	0.518
LIG_FHA_2	43	49	PF00498	0.636
LIG_FHA_2	501	507	PF00498	0.338
LIG_FHA_2	539	545	PF00498	0.440
LIG_FHA_2	562	568	PF00498	0.378
LIG_FHA_2	692	698	PF00498	0.604
LIG_FHA_2	931	937	PF00498	0.622
LIG_FHA_2	966	972	PF00498	0.592
LIG_Integrin_RGD_1	354	356	PF01839	0.519
LIG_LIR_Apic_2	154	160	PF02991	0.530
LIG_LIR_Apic_2	636	640	PF02991	0.377
LIG_LIR_Gen_1	321	331	PF02991	0.312
LIG_LIR_Gen_1	370	377	PF02991	0.294
LIG_LIR_Gen_1	403	414	PF02991	0.244
LIG_LIR_Gen_1	461	470	PF02991	0.431
LIG_LIR_Gen_1	506	516	PF02991	0.385
LIG_LIR_Gen_1	599	610	PF02991	0.450
LIG_LIR_Gen_1	632	641	PF02991	0.521
LIG_LIR_Nem_3	321	326	PF02991	0.312
LIG_LIR_Nem_3	341	347	PF02991	0.257
LIG_LIR_Nem_3	370	376	PF02991	0.294
LIG_LIR_Nem_3	39	44	PF02991	0.623
LIG_LIR_Nem_3	403	409	PF02991	0.257
LIG_LIR_Nem_3	461	465	PF02991	0.391
LIG_LIR_Nem_3	506	511	PF02991	0.367
LIG_LIR_Nem_3	599	605	PF02991	0.455
LIG_LIR_Nem_3	632	637	PF02991	0.516
LIG_Pex14_2	371	375	PF04695	0.292
LIG_Pex14_2	637	641	PF04695	0.363
LIG_PTB_Apo_2	622	629	PF02174	0.481
LIG_PTB_Phospho_1	622	628	PF10480	0.475
LIG_SH2_CRK	397	401	PF00017	0.336
LIG_SH2_CRK	406	410	PF00017	0.342
LIG_SH2_CRK	462	466	PF00017	0.376
LIG_SH2_GRB2like	57	60	PF00017	0.595
LIG_SH2_GRB2like	623	626	PF00017	0.463
LIG_SH2_GRB2like	730	733	PF00017	0.609
LIG_SH2_PTP2	508	511	PF00017	0.457
LIG_SH2_PTP2	602	605	PF00017	0.449
LIG_SH2_SRC	226	229	PF00017	0.474
LIG_SH2_SRC	464	467	PF00017	0.471
LIG_SH2_SRC	57	60	PF00017	0.547
LIG_SH2_SRC	623	626	PF00017	0.392
LIG_SH2_STAP1	406	410	PF00017	0.237
LIG_SH2_STAP1	631	635	PF00017	0.444
LIG_SH2_STAP1	911	915	PF00017	0.662
LIG_SH2_STAT3	730	733	PF00017	0.649
LIG_SH2_STAT5	226	229	PF00017	0.502
LIG_SH2_STAT5	295	298	PF00017	0.553
LIG_SH2_STAT5	383	386	PF00017	0.414
LIG_SH2_STAT5	431	434	PF00017	0.418
LIG_SH2_STAT5	464	467	PF00017	0.436
LIG_SH2_STAT5	508	511	PF00017	0.487
LIG_SH2_STAT5	569	572	PF00017	0.430
LIG_SH2_STAT5	602	605	PF00017	0.449
LIG_SH2_STAT5	623	626	PF00017	0.392
LIG_SH2_STAT5	628	631	PF00017	0.461
LIG_SH2_STAT5	634	637	PF00017	0.409
LIG_SH2_STAT5	638	641	PF00017	0.385
LIG_SH2_STAT5	730	733	PF00017	0.649
LIG_SH2_STAT5	803	806	PF00017	0.532
LIG_SH3_3	143	149	PF00018	0.456
LIG_SH3_3	355	361	PF00018	0.541
LIG_SH3_3	462	468	PF00018	0.487
LIG_SH3_3	498	504	PF00018	0.369
LIG_SH3_3	555	561	PF00018	0.497
LIG_SH3_3	578	584	PF00018	0.467
LIG_SH3_3	602	608	PF00018	0.443
LIG_SH3_3	624	630	PF00018	0.505
LIG_SUMO_SIM_anti_2	301	308	PF11976	0.328
LIG_SUMO_SIM_anti_2	310	316	PF11976	0.310
LIG_SUMO_SIM_anti_2	506	515	PF11976	0.327
LIG_SUMO_SIM_par_1	188	193	PF11976	0.454
LIG_SUMO_SIM_par_1	198	203	PF11976	0.437
LIG_TRAF2_1	28	31	PF00917	0.678
LIG_TRAF2_1	828	831	PF00917	0.492
LIG_TYR_ITIM	342	347	PF00017	0.364
LIG_TYR_ITIM	621	626	PF00017	0.429
LIG_UBA3_1	3	8	PF00899	0.434
LIG_WW_3	582	586	PF00397	0.519
MOD_CDK_SPxxK_3	768	775	PF00069	0.557
MOD_CK1_1	251	257	PF00069	0.582
MOD_CK1_1	327	333	PF00069	0.425
MOD_CK1_1	429	435	PF00069	0.447
MOD_CK1_1	450	456	PF00069	0.320
MOD_CK1_1	542	548	PF00069	0.506
MOD_CK1_1	704	710	PF00069	0.648
MOD_CK1_1	83	89	PF00069	0.662
MOD_CK1_1	918	924	PF00069	0.525
MOD_CK2_1	21	27	PF00069	0.540
MOD_CK2_1	267	273	PF00069	0.701
MOD_CK2_1	432	438	PF00069	0.442
MOD_CK2_1	500	506	PF00069	0.386
MOD_CK2_1	561	567	PF00069	0.382
MOD_CK2_1	586	592	PF00069	0.474
MOD_CK2_1	825	831	PF00069	0.447
MOD_CK2_1	83	89	PF00069	0.648
MOD_CK2_1	965	971	PF00069	0.595
MOD_Cter_Amidation	277	280	PF01082	0.768
MOD_GlcNHglycan	250	253	PF01048	0.530
MOD_GlcNHglycan	282	285	PF01048	0.631
MOD_GlcNHglycan	350	353	PF01048	0.468
MOD_GlcNHglycan	493	496	PF01048	0.445
MOD_GlcNHglycan	557	561	PF01048	0.497
MOD_GlcNHglycan	658	661	PF01048	0.751
MOD_GlcNHglycan	663	666	PF01048	0.779
MOD_GlcNHglycan	689	692	PF01048	0.655
MOD_GlcNHglycan	703	706	PF01048	0.733
MOD_GlcNHglycan	722	725	PF01048	0.460
MOD_GlcNHglycan	746	749	PF01048	0.504
MOD_GlcNHglycan	759	762	PF01048	0.428
MOD_GlcNHglycan	788	791	PF01048	0.586
MOD_GlcNHglycan	858	861	PF01048	0.702
MOD_GlcNHglycan	876	879	PF01048	0.620
MOD_GlcNHglycan	944	947	PF01048	0.720
MOD_GSK3_1	174	181	PF00069	0.342
MOD_GSK3_1	186	193	PF00069	0.329
MOD_GSK3_1	248	255	PF00069	0.533
MOD_GSK3_1	350	357	PF00069	0.482
MOD_GSK3_1	359	366	PF00069	0.430
MOD_GSK3_1	396	403	PF00069	0.409
MOD_GSK3_1	404	411	PF00069	0.431
MOD_GSK3_1	425	432	PF00069	0.412
MOD_GSK3_1	496	503	PF00069	0.426
MOD_GSK3_1	514	521	PF00069	0.334
MOD_GSK3_1	531	538	PF00069	0.490
MOD_GSK3_1	687	694	PF00069	0.730
MOD_GSK3_1	701	708	PF00069	0.552
MOD_GSK3_1	79	86	PF00069	0.654
MOD_GSK3_1	856	863	PF00069	0.727
MOD_GSK3_1	9	16	PF00069	0.409
MOD_GSK3_1	930	937	PF00069	0.610
MOD_GSK3_1	965	972	PF00069	0.719
MOD_LATS_1	678	684	PF00433	0.654
MOD_N-GLC_1	324	329	PF02516	0.418
MOD_N-GLC_1	542	547	PF02516	0.456
MOD_N-GLC_1	58	63	PF02516	0.513
MOD_NEK2_1	178	183	PF00069	0.284
MOD_NEK2_1	190	195	PF00069	0.284
MOD_NEK2_1	227	232	PF00069	0.287
MOD_NEK2_1	313	318	PF00069	0.315
MOD_NEK2_1	347	352	PF00069	0.559
MOD_NEK2_1	596	601	PF00069	0.444
MOD_NEK2_1	687	692	PF00069	0.677
MOD_NEK2_1	699	704	PF00069	0.679
MOD_NEK2_1	756	761	PF00069	0.414
MOD_NEK2_1	79	84	PF00069	0.795
MOD_NEK2_1	9	14	PF00069	0.417
MOD_NEK2_1	915	920	PF00069	0.613
MOD_NEK2_2	447	452	PF00069	0.330
MOD_OFUCOSY	112	117	PF10250	0.381
MOD_PIKK_1	165	171	PF00454	0.284
MOD_PIKK_1	205	211	PF00454	0.379
MOD_PIKK_1	359	365	PF00454	0.437
MOD_PIKK_1	496	502	PF00454	0.519
MOD_PIKK_1	887	893	PF00454	0.554
MOD_PK_1	396	402	PF00069	0.360
MOD_PKA_1	174	180	PF00069	0.344
MOD_PKA_1	279	285	PF00069	0.578
MOD_PKA_1	586	592	PF00069	0.450
MOD_PKA_2	149	155	PF00069	0.344
MOD_PKA_2	174	180	PF00069	0.231
MOD_PKA_2	279	285	PF00069	0.578
MOD_PKA_2	337	343	PF00069	0.439
MOD_PKA_2	400	406	PF00069	0.455
MOD_PKA_2	586	592	PF00069	0.450
MOD_PKA_2	672	678	PF00069	0.752
MOD_PKA_2	744	750	PF00069	0.586
MOD_PKB_1	172	180	PF00069	0.344
MOD_Plk_1	300	306	PF00069	0.344
MOD_Plk_1	324	330	PF00069	0.416
MOD_Plk_1	514	520	PF00069	0.413
MOD_Plk_1	960	966	PF00069	0.472
MOD_Plk_4	174	180	PF00069	0.373
MOD_Plk_4	193	199	PF00069	0.284
MOD_Plk_4	228	234	PF00069	0.368
MOD_Plk_4	300	306	PF00069	0.386
MOD_Plk_4	405	411	PF00069	0.459
MOD_Plk_4	450	456	PF00069	0.375
MOD_Plk_4	504	510	PF00069	0.315
MOD_Plk_4	531	537	PF00069	0.495
MOD_Plk_4	960	966	PF00069	0.472
MOD_ProDKin_1	258	264	PF00069	0.653
MOD_ProDKin_1	327	333	PF00069	0.412
MOD_ProDKin_1	354	360	PF00069	0.510
MOD_ProDKin_1	408	414	PF00069	0.404
MOD_ProDKin_1	500	506	PF00069	0.347
MOD_ProDKin_1	572	578	PF00069	0.476
MOD_ProDKin_1	610	616	PF00069	0.307
MOD_ProDKin_1	691	697	PF00069	0.695
MOD_ProDKin_1	768	774	PF00069	0.557
MOD_ProDKin_1	825	831	PF00069	0.540
MOD_ProDKin_1	83	89	PF00069	0.600
MOD_ProDKin_1	965	971	PF00069	0.614
MOD_SUMO_rev_2	122	127	PF00179	0.324
MOD_SUMO_rev_2	235	241	PF00179	0.284
MOD_SUMO_rev_2	739	748	PF00179	0.490
MOD_SUMO_rev_2	799	804	PF00179	0.593
TRG_DiLeu_BaEn_1	831	836	PF01217	0.421
TRG_DiLeu_BaEn_2	817	823	PF01217	0.506
TRG_DiLeu_BaEn_4	960	966	PF01217	0.472
TRG_DiLeu_BaLyEn_6	14	19	PF01217	0.484
TRG_ENDOCYTIC_2	344	347	PF00928	0.356
TRG_ENDOCYTIC_2	397	400	PF00928	0.339
TRG_ENDOCYTIC_2	406	409	PF00928	0.353
TRG_ENDOCYTIC_2	41	44	PF00928	0.634
TRG_ENDOCYTIC_2	462	465	PF00928	0.378
TRG_ENDOCYTIC_2	508	511	PF00928	0.457
TRG_ENDOCYTIC_2	602	605	PF00928	0.449
TRG_ENDOCYTIC_2	623	626	PF00928	0.424
TRG_ENDOCYTIC_2	634	637	PF00928	0.465
TRG_ENDOCYTIC_2	638	641	PF00928	0.452
TRG_ENDOCYTIC_2	99	102	PF00928	0.548
TRG_ER_diArg_1	138	141	PF00400	0.344
TRG_ER_diArg_1	170	173	PF00400	0.301
TRG_ER_diArg_1	174	176	PF00400	0.301
TRG_ER_diArg_1	219	221	PF00400	0.379
TRG_ER_diArg_1	268	271	PF00400	0.529
TRG_ER_diArg_1	296	299	PF00400	0.517
TRG_ER_diArg_1	34	37	PF00400	0.617
TRG_ER_diArg_1	394	396	PF00400	0.444
TRG_ER_diArg_1	584	587	PF00400	0.544
TRG_ER_diArg_1	727	729	PF00400	0.538
TRG_ER_diArg_1	740	743	PF00400	0.711
TRG_ER_diArg_1	76	78	PF00400	0.643
TRG_ER_diArg_1	775	777	PF00400	0.503
TRG_ER_diArg_1	779	781	PF00400	0.490
TRG_ER_diArg_1	882	885	PF00400	0.664
TRG_ER_diArg_1	925	928	PF00400	0.611
TRG_ER_diArg_1	950	953	PF00400	0.645
TRG_ER_diArg_1	975	977	PF00400	0.678
TRG_NES_CRM1_1	130	145	PF08389	0.400
TRG_NES_CRM1_1	500	515	PF08389	0.467
TRG_NLS_MonoCore_2	924	929	PF00514	0.565
TRG_NLS_MonoCore_2	948	953	PF00514	0.578
TRG_NLS_MonoCore_2	972	977	PF00514	0.674
TRG_NLS_MonoExtC_3	32	37	PF00514	0.572
TRG_NLS_MonoExtC_3	948	953	PF00514	0.622
TRG_NLS_MonoExtC_3	972	977	PF00514	0.674
TRG_NLS_MonoExtN_4	923	930	PF00514	0.624
TRG_NLS_MonoExtN_4	973	978	PF00514	0.679
TRG_Pf-PMV_PEXEL_1	129	133	PF00026	0.280
TRG_Pf-PMV_PEXEL_1	140	145	PF00026	0.352
TRG_Pf-PMV_PEXEL_1	34	39	PF00026	0.590
TRG_Pf-PMV_PEXEL_1	813	818	PF00026	0.669

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IM29	Leptomonas seymouri	67%	100%
A0A1X0NZ48	Trypanosomatidae	45%	100%
A0A3R7RG04	Trypanosoma rangeli	41%	100%
A0A3S7WTU7	Leishmania donovani	86%	98%
A4H8G4	Leishmania braziliensis	76%	100%
A4HWT8	Leishmania infantum	86%	98%
C9ZPR7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	100%
Q4QEY1	Leishmania major	88%	100%