| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 2 |
| Forrest at al. (procyclic) | no | yes: 4 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | yes | yes: 27 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 5 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 10 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 23 |
| NetGPI | no | yes: 0, no: 23 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005634 | nucleus | 5 | 2 |
| GO:0005737 | cytoplasm | 2 | 2 |
| GO:0005829 | cytosol | 2 | 1 |
| GO:0018995 | host cellular component | 2 | 1 |
| GO:0020023 | kinetoplast | 2 | 1 |
| GO:0030430 | host cell cytoplasm | 5 | 1 |
| GO:0031982 | vesicle | 4 | 1 |
| GO:0033643 | host cell part | 3 | 1 |
| GO:0033646 | host intracellular part | 4 | 1 |
| GO:0043226 | organelle | 2 | 2 |
| GO:0043227 | membrane-bounded organelle | 3 | 2 |
| GO:0043229 | intracellular organelle | 3 | 2 |
| GO:0043230 | extracellular organelle | 3 | 1 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 2 |
| GO:0065010 | extracellular membrane-bounded organelle | 4 | 1 |
| GO:0070062 | extracellular exosome | 6 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 2 |
| GO:1903561 | extracellular vesicle | 5 | 1 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006470 | protein dephosphorylation | 5 | 24 |
| GO:0006793 | phosphorus metabolic process | 3 | 24 |
| GO:0006796 | phosphate-containing compound metabolic process | 4 | 24 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 24 |
| GO:0008152 | metabolic process | 1 | 24 |
| GO:0009987 | cellular process | 1 | 24 |
| GO:0016311 | dephosphorylation | 5 | 24 |
| GO:0019538 | protein metabolic process | 3 | 24 |
| GO:0036211 | protein modification process | 4 | 24 |
| GO:0043170 | macromolecule metabolic process | 3 | 24 |
| GO:0043412 | macromolecule modification | 4 | 24 |
| GO:0044237 | cellular metabolic process | 2 | 24 |
| GO:0044238 | primary metabolic process | 2 | 24 |
| GO:0071704 | organic substance metabolic process | 2 | 24 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 24 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 24 |
| GO:0004721 | phosphoprotein phosphatase activity | 3 | 24 |
| GO:0004725 | protein tyrosine phosphatase activity | 4 | 17 |
| GO:0008138 | protein tyrosine/serine/threonine phosphatase activity | 4 | 24 |
| GO:0016787 | hydrolase activity | 2 | 24 |
| GO:0016788 | hydrolase activity, acting on ester bonds | 3 | 24 |
| GO:0016791 | phosphatase activity | 5 | 24 |
| GO:0042578 | phosphoric ester hydrolase activity | 4 | 24 |
| GO:0140096 | catalytic activity, acting on a protein | 2 | 24 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_C14_Caspase3-7 | 136 | 140 | PF00656 | 0.397 |
| CLV_NRD_NRD_1 | 147 | 149 | PF00675 | 0.303 |
| CLV_NRD_NRD_1 | 165 | 167 | PF00675 | 0.554 |
| CLV_PCSK_FUR_1 | 145 | 149 | PF00082 | 0.303 |
| CLV_PCSK_KEX2_1 | 147 | 149 | PF00082 | 0.303 |
| CLV_PCSK_KEX2_1 | 164 | 166 | PF00082 | 0.559 |
| CLV_PCSK_PC1ET2_1 | 147 | 149 | PF00082 | 0.308 |
| CLV_PCSK_PC1ET2_1 | 164 | 166 | PF00082 | 0.508 |
| CLV_PCSK_SKI1_1 | 18 | 22 | PF00082 | 0.514 |
| CLV_PCSK_SKI1_1 | 82 | 86 | PF00082 | 0.345 |
| DEG_Nend_UBRbox_2 | 1 | 3 | PF02207 | 0.553 |
| DOC_CDC14_PxL_1 | 118 | 126 | PF14671 | 0.303 |
| DOC_MAPK_gen_1 | 44 | 52 | PF00069 | 0.419 |
| DOC_MAPK_MEF2A_6 | 120 | 129 | PF00069 | 0.306 |
| DOC_PP1_RVXF_1 | 16 | 22 | PF00149 | 0.561 |
| DOC_PP2B_LxvP_1 | 26 | 29 | PF13499 | 0.528 |
| DOC_PP2B_PxIxI_1 | 107 | 113 | PF00149 | 0.446 |
| DOC_USP7_MATH_1 | 29 | 33 | PF00917 | 0.507 |
| DOC_WW_Pin1_4 | 27 | 32 | PF00397 | 0.504 |
| LIG_BRCT_BRCA1_1 | 70 | 74 | PF00533 | 0.325 |
| LIG_Clathr_ClatBox_1 | 91 | 95 | PF01394 | 0.252 |
| LIG_FHA_1 | 107 | 113 | PF00498 | 0.334 |
| LIG_FHA_1 | 79 | 85 | PF00498 | 0.369 |
| LIG_FHA_2 | 4 | 10 | PF00498 | 0.521 |
| LIG_LIR_Gen_1 | 86 | 96 | PF02991 | 0.345 |
| LIG_LIR_Nem_3 | 131 | 135 | PF02991 | 0.325 |
| LIG_LIR_Nem_3 | 86 | 91 | PF02991 | 0.325 |
| LIG_Pex14_1 | 159 | 163 | PF04695 | 0.545 |
| LIG_SH2_CRK | 132 | 136 | PF00017 | 0.369 |
| LIG_SH2_STAP1 | 57 | 61 | PF00017 | 0.519 |
| LIG_SH2_STAT5 | 37 | 40 | PF00017 | 0.484 |
| LIG_SH3_2 | 13 | 18 | PF14604 | 0.484 |
| LIG_SH3_3 | 10 | 16 | PF00018 | 0.480 |
| LIG_SH3_3 | 100 | 106 | PF00018 | 0.280 |
| LIG_SH3_3 | 49 | 55 | PF00018 | 0.465 |
| LIG_SUMO_SIM_anti_2 | 139 | 146 | PF11976 | 0.310 |
| LIG_TYR_ITIM | 130 | 135 | PF00017 | 0.345 |
| MOD_CAAXbox | 172 | 175 | PF01239 | 0.569 |
| MOD_GlcNHglycan | 135 | 138 | PF01048 | 0.397 |
| MOD_GSK3_1 | 29 | 36 | PF00069 | 0.581 |
| MOD_GSK3_1 | 53 | 60 | PF00069 | 0.513 |
| MOD_N-GLC_1 | 133 | 138 | PF02516 | 0.491 |
| MOD_N-GLC_1 | 3 | 8 | PF02516 | 0.502 |
| MOD_NEK2_1 | 61 | 66 | PF00069 | 0.437 |
| MOD_Plk_1 | 133 | 139 | PF00069 | 0.491 |
| MOD_Plk_1 | 3 | 9 | PF00069 | 0.492 |
| MOD_Plk_1 | 57 | 63 | PF00069 | 0.512 |
| MOD_Plk_4 | 3 | 9 | PF00069 | 0.513 |
| MOD_Plk_4 | 33 | 39 | PF00069 | 0.613 |
| MOD_Plk_4 | 57 | 63 | PF00069 | 0.544 |
| MOD_Plk_4 | 84 | 90 | PF00069 | 0.325 |
| MOD_ProDKin_1 | 27 | 33 | PF00069 | 0.502 |
| TRG_ENDOCYTIC_2 | 132 | 135 | PF00928 | 0.317 |
| TRG_NLS_Bipartite_1 | 147 | 168 | PF00514 | 0.645 |
| TRG_NLS_MonoExtN_4 | 162 | 168 | PF00514 | 0.649 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P7Y8 | Leptomonas seymouri | 78% | 99% |
| A0A0N1IM31 | Leptomonas seymouri | 60% | 99% |
| A0A0S4IS65 | Bodo saltans | 60% | 97% |
| A0A1X0NFW2 | Trypanosomatidae | 67% | 99% |
| A0A1X0NHQ7 | Trypanosomatidae | 59% | 99% |
| A0A1X0NZ52 | Trypanosomatidae | 67% | 99% |
| A0A3Q8I9A9 | Leishmania donovani | 97% | 100% |
| A0A3S5IQZ9 | Trypanosoma rangeli | 57% | 99% |
| A0A3S7WTS0 | Leishmania donovani | 62% | 99% |
| A0A422N2F6 | Trypanosoma rangeli | 53% | 100% |
| A0A422ND97 | Trypanosoma rangeli | 66% | 99% |
| A2VDT1 | Bos taurus | 45% | 100% |
| A4H8E9 | Leishmania braziliensis | 89% | 100% |
| A4H8F1 | Leishmania braziliensis | 61% | 100% |
| A4HWS2 | Leishmania infantum | 96% | 100% |
| A4HWS4 | Leishmania infantum | 62% | 99% |
| C9ZW52 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 69% | 99% |
| E9AQI2 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 62% | 99% |
| O61722 | Drosophila melanogaster | 43% | 99% |
| O70274 | Mus musculus | 47% | 100% |
| O75365 | Homo sapiens | 45% | 100% |
| Q12974 | Homo sapiens | 47% | 100% |
| Q4CUJ8 | Trypanosoma cruzi (strain CL Brener) | 53% | 99% |
| Q4QEZ5 | Leishmania major | 61% | 100% |
| Q4QEZ7 | Leishmania major | 97% | 100% |
| Q54DU9 | Dictyostelium discoideum | 48% | 100% |
| Q5R7J8 | Pongo abelii | 48% | 100% |
| Q63739 | Mus musculus | 49% | 100% |
| Q6NT99 | Mus musculus | 33% | 100% |
| Q6P9X4 | Rattus norvegicus | 47% | 100% |
| Q78EG7 | Rattus norvegicus | 49% | 100% |
| Q86IL4 | Dictyostelium discoideum | 34% | 100% |
| Q93096 | Homo sapiens | 49% | 100% |
| Q9BVJ7 | Homo sapiens | 32% | 100% |
| Q9D658 | Mus musculus | 47% | 100% |
| Q9TSM6 | Macaca fascicularis | 49% | 100% |
| V5B959 | Trypanosoma cruzi | 66% | 97% |
| V5BA64 | Trypanosoma cruzi | 53% | 99% |
| V5BDR5 | Trypanosoma cruzi | 57% | 99% |