Ski2_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AQH2_LEIMU

TriTrypDb:

LmxM.16.0150

Length:

205

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQH2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQH2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	132	134	PF00675	0.558
CLV_NRD_NRD_1	96	98	PF00675	0.671
CLV_PCSK_KEX2_1	132	134	PF00082	0.721
CLV_PCSK_KEX2_1	56	58	PF00082	0.440
CLV_PCSK_KEX2_1	96	98	PF00082	0.621
CLV_PCSK_PC1ET2_1	56	58	PF00082	0.440
CLV_PCSK_PC7_1	128	134	PF00082	0.563
CLV_PCSK_SKI1_1	132	136	PF00082	0.583
DEG_APCC_DBOX_1	96	104	PF00400	0.485
DEG_SCF_FBW7_1	79	86	PF00400	0.568
DOC_CYCLIN_yCln2_LP_2	135	141	PF00134	0.624
DOC_PP2B_LxvP_1	135	138	PF13499	0.618
DOC_USP7_MATH_1	149	153	PF00917	0.740
DOC_USP7_MATH_1	199	203	PF00917	0.455
DOC_USP7_MATH_1	85	89	PF00917	0.552
DOC_WW_Pin1_4	122	127	PF00397	0.532
DOC_WW_Pin1_4	166	171	PF00397	0.777
DOC_WW_Pin1_4	65	70	PF00397	0.644
DOC_WW_Pin1_4	77	82	PF00397	0.603
DOC_WW_Pin1_4	83	88	PF00397	0.640
LIG_deltaCOP1_diTrp_1	172	179	PF00928	0.460
LIG_FHA_1	192	198	PF00498	0.481
LIG_Integrin_isoDGR_2	156	158	PF01839	0.652
LIG_LIR_Gen_1	44	53	PF02991	0.608
LIG_LIR_Nem_3	24	28	PF02991	0.512
LIG_LIR_Nem_3	44	48	PF02991	0.582
LIG_Pex14_2	179	183	PF04695	0.539
LIG_SH2_CRK	45	49	PF00017	0.611
LIG_SH2_STAP1	45	49	PF00017	0.611
LIG_SH3_1	96	102	PF00018	0.483
LIG_SH3_3	167	173	PF00018	0.575
LIG_SH3_3	34	40	PF00018	0.573
LIG_SH3_3	84	90	PF00018	0.560
LIG_SH3_3	95	101	PF00018	0.549
LIG_TRAF2_1	90	93	PF00917	0.557
MOD_CDC14_SPxK_1	86	89	PF00782	0.562
MOD_CDK_SPxK_1	122	128	PF00069	0.531
MOD_CDK_SPxK_1	83	89	PF00069	0.563
MOD_CK2_1	166	172	PF00069	0.485
MOD_Cter_Amidation	54	57	PF01082	0.457
MOD_GlcNHglycan	50	53	PF01048	0.522
MOD_GSK3_1	79	86	PF00069	0.568
MOD_NEK2_1	48	53	PF00069	0.473
MOD_ProDKin_1	122	128	PF00069	0.535
MOD_ProDKin_1	166	172	PF00069	0.776
MOD_ProDKin_1	65	71	PF00069	0.650
MOD_ProDKin_1	77	83	PF00069	0.601
MOD_SUMO_rev_2	184	191	PF00179	0.470
TRG_ENDOCYTIC_2	45	48	PF00928	0.611
TRG_ER_diArg_1	40	43	PF00400	0.498
TRG_ER_diArg_1	95	97	PF00400	0.622

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFT2	Leptomonas seymouri	45%	94%
A0A3S7WTR0	Leishmania donovani	85%	87%
A4HWR4	Leishmania infantum	85%	87%
Q4QF05	Leishmania major	86%	100%