Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AQG9_LEIMU

TriTrypDb:

LmxM.16.0130 , LmxM.16.0131

Length:

208

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQG9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQG9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	168	172	PF00656	0.660
CLV_NRD_NRD_1	116	118	PF00675	0.486
CLV_NRD_NRD_1	121	123	PF00675	0.519
CLV_NRD_NRD_1	68	70	PF00675	0.666
CLV_PCSK_FUR_1	113	117	PF00082	0.385
CLV_PCSK_KEX2_1	115	117	PF00082	0.425
CLV_PCSK_KEX2_1	68	70	PF00082	0.617
CLV_PCSK_SKI1_1	122	126	PF00082	0.490
DEG_APCC_DBOX_1	114	122	PF00400	0.637
DEG_APCC_DBOX_1	68	76	PF00400	0.746
DOC_CYCLIN_RxL_1	116	130	PF00134	0.536
DOC_MAPK_gen_1	115	126	PF00069	0.540
DOC_MAPK_MEF2A_6	120	128	PF00069	0.547
DOC_USP7_MATH_1	144	148	PF00917	0.611
DOC_USP7_MATH_1	163	167	PF00917	0.654
DOC_USP7_MATH_1	174	178	PF00917	0.589
DOC_USP7_MATH_1	44	48	PF00917	0.683
DOC_USP7_MATH_1	91	95	PF00917	0.630
DOC_USP7_UBL2_3	39	43	PF12436	0.660
DOC_WW_Pin1_4	140	145	PF00397	0.706
LIG_14-3-3_CanoR_1	93	103	PF00244	0.441
LIG_14-3-3_CterR_2	204	208	PF00244	0.579
LIG_Actin_WH2_2	114	129	PF00022	0.377
LIG_Actin_WH2_2	191	208	PF00022	0.536
LIG_deltaCOP1_diTrp_1	182	191	PF00928	0.668
LIG_FHA_1	165	171	PF00498	0.773
LIG_FHA_1	48	54	PF00498	0.671
LIG_FHA_1	94	100	PF00498	0.702
LIG_FHA_2	166	172	PF00498	0.703
LIG_FHA_2	2	8	PF00498	0.707
LIG_MYND_1	140	144	PF01753	0.730
LIG_SH3_3	76	82	PF00018	0.676
LIG_TRAF2_1	132	135	PF00917	0.668
MOD_CK1_1	143	149	PF00069	0.733
MOD_CK1_1	47	53	PF00069	0.675
MOD_CK1_1	94	100	PF00069	0.562
MOD_CK2_1	128	134	PF00069	0.543
MOD_CK2_1	15	21	PF00069	0.628
MOD_GlcNHglycan	55	58	PF01048	0.419
MOD_GlcNHglycan	82	85	PF01048	0.512
MOD_GlcNHglycan	96	99	PF01048	0.638
MOD_GSK3_1	140	147	PF00069	0.677
MOD_GSK3_1	161	168	PF00069	0.661
MOD_GSK3_1	174	181	PF00069	0.547
MOD_GSK3_1	87	94	PF00069	0.496
MOD_NEK2_1	1	6	PF00069	0.690
MOD_NEK2_1	161	166	PF00069	0.500
MOD_NEK2_1	198	203	PF00069	0.583
MOD_NEK2_1	53	58	PF00069	0.404
MOD_PIKK_1	161	167	PF00454	0.685
MOD_PKA_2	174	180	PF00069	0.741
MOD_PKA_2	92	98	PF00069	0.469
MOD_Plk_1	129	135	PF00069	0.475
MOD_Plk_4	165	171	PF00069	0.729
MOD_Plk_4	198	204	PF00069	0.643
MOD_ProDKin_1	140	146	PF00069	0.705
MOD_SUMO_rev_2	192	198	PF00179	0.522
TRG_ENDOCYTIC_2	30	33	PF00928	0.500
TRG_ER_diArg_1	115	117	PF00400	0.648
TRG_ER_diArg_1	203	206	PF00400	0.543
TRG_NLS_MonoExtN_4	120	126	PF00514	0.518

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0H3	Leptomonas seymouri	31%	100%
A0A3Q8IIW8	Leishmania donovani	80%	100%
A4HWR2	Leishmania infantum	81%	100%
Q4QF07	Leishmania major	78%	100%