LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Secreted protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AQE9_LEIMU
TriTrypDb:
LmxM.15.1520
Length:
95

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQE9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQE9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 50 54 PF00656 0.607
DEG_Nend_UBRbox_4 1 3 PF02207 0.512
DOC_PP2B_LxvP_1 6 9 PF13499 0.484
DOC_USP7_UBL2_3 42 46 PF12436 0.682
DOC_WW_Pin1_4 81 86 PF00397 0.775
LIG_BRCT_BRCA1_1 31 35 PF00533 0.685
LIG_FHA_1 17 23 PF00498 0.478
LIG_FHA_1 32 38 PF00498 0.482
LIG_LIR_Gen_1 21 31 PF02991 0.541
LIG_LIR_Nem_3 21 26 PF02991 0.541
LIG_NRP_CendR_1 92 95 PF00754 0.762
LIG_SH2_CRK 4 8 PF00017 0.497
LIG_SH3_2 41 46 PF14604 0.595
LIG_SH3_3 38 44 PF00018 0.598
LIG_SUMO_SIM_par_1 18 25 PF11976 0.481
LIG_TRAF2_2 45 50 PF00917 0.491
MOD_CK1_1 16 22 PF00069 0.582
MOD_CK1_1 25 31 PF00069 0.538
MOD_CK2_1 68 74 PF00069 0.706
MOD_GSK3_1 18 25 PF00069 0.668
MOD_LATS_1 73 79 PF00433 0.756
MOD_N-GLC_1 29 34 PF02516 0.613
MOD_N-GLC_1 81 86 PF02516 0.775
MOD_NEK2_1 31 36 PF00069 0.702
MOD_NEK2_2 18 23 PF00069 0.558
MOD_PKA_2 13 19 PF00069 0.477
MOD_Plk_4 18 24 PF00069 0.668
MOD_Plk_4 31 37 PF00069 0.702
MOD_ProDKin_1 81 87 PF00069 0.774
TRG_ENDOCYTIC_2 4 7 PF00928 0.496
TRG_ER_diLys_1 90 95 PF00400 0.761

Homologs

Protein Taxonomy Sequence identity Coverage
A4HWP1 Leishmania infantum 81% 100%
Q4QF27 Leishmania major 82% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS