LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AQD8_LEIMU
TriTrypDb:
LmxM.15.1430
Length:
95

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQD8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQD8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 65 67 PF00675 0.520
CLV_PCSK_KEX2_1 65 67 PF00082 0.520
CLV_PCSK_SKI1_1 77 81 PF00082 0.588
DEG_SCF_FBW7_1 1 8 PF00400 0.706
DOC_CYCLIN_yClb5_NLxxxL_5 65 73 PF00134 0.537
DOC_MAPK_RevD_3 73 87 PF00069 0.530
DOC_USP7_MATH_1 11 15 PF00917 0.545
DOC_USP7_MATH_1 5 9 PF00917 0.707
DOC_USP7_MATH_1 51 55 PF00917 0.615
DOC_WW_Pin1_4 1 6 PF00397 0.640
DOC_WW_Pin1_4 37 42 PF00397 0.605
LIG_14-3-3_CanoR_1 33 41 PF00244 0.720
LIG_BIR_II_1 1 5 PF00653 0.642
LIG_FHA_1 17 23 PF00498 0.706
LIG_FHA_1 26 32 PF00498 0.669
LIG_FHA_2 2 8 PF00498 0.707
LIG_FHA_2 38 44 PF00498 0.612
LIG_SH2_STAT5 82 85 PF00017 0.456
MOD_CK2_1 11 17 PF00069 0.784
MOD_CK2_1 37 43 PF00069 0.730
MOD_GlcNHglycan 7 10 PF01048 0.611
MOD_GSK3_1 1 8 PF00069 0.666
MOD_GSK3_1 16 23 PF00069 0.647
MOD_GSK3_1 33 40 PF00069 0.714
MOD_PKA_2 32 38 PF00069 0.726
MOD_ProDKin_1 1 7 PF00069 0.642
MOD_ProDKin_1 37 43 PF00069 0.604
TRG_ER_diArg_1 65 67 PF00400 0.523

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I0X5 Leptomonas seymouri 33% 100%
A0A3Q8IA91 Leishmania donovani 87% 100%
A0A3R7K7I4 Trypanosoma rangeli 33% 88%
A4HWN0 Leishmania infantum 87% 100%
E9AI51 Leishmania braziliensis 58% 100%
Q4QF37 Leishmania major 84% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS