LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AQ85_LEIMU
TriTrypDb:
LmxM.15.0860
Length:
316

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQ85
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQ85

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 285 289 PF00656 0.630
CLV_NRD_NRD_1 312 314 PF00675 0.708
CLV_NRD_NRD_1 40 42 PF00675 0.500
CLV_PCSK_KEX2_1 40 42 PF00082 0.500
CLV_PCSK_SKI1_1 54 58 PF00082 0.554
CLV_Separin_Metazoa 51 55 PF03568 0.436
DEG_APCC_DBOX_1 98 106 PF00400 0.426
DEG_SPOP_SBC_1 214 218 PF00917 0.688
DEG_SPOP_SBC_1 60 64 PF00917 0.561
DOC_CYCLIN_RxL_1 88 100 PF00134 0.394
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S7WTH2 Leishmania donovani 75% 98%
A4H858 Leishmania braziliensis 57% 100%
A4HWI4 Leishmania infantum 74% 98%
Q4QF98 Leishmania major 74% 98%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS