Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AQ84_LEIMU

TriTrypDb:

LmxM.15.0850

Length:

955

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQ84

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQ84

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	120	124	PF00656	0.507
CLV_NRD_NRD_1	153	155	PF00675	0.774
CLV_NRD_NRD_1	218	220	PF00675	0.734
CLV_NRD_NRD_1	24	26	PF00675	0.585
CLV_NRD_NRD_1	33	35	PF00675	0.614
CLV_NRD_NRD_1	39	41	PF00675	0.480
CLV_NRD_NRD_1	390	392	PF00675	0.803
CLV_NRD_NRD_1	444	446	PF00675	0.804
CLV_NRD_NRD_1	467	469	PF00675	0.786
CLV_NRD_NRD_1	51	53	PF00675	0.341
CLV_NRD_NRD_1	586	588	PF00675	0.486
CLV_NRD_NRD_1	594	596	PF00675	0.346
CLV_NRD_NRD_1	639	641	PF00675	0.558
CLV_NRD_NRD_1	645	647	PF00675	0.525
CLV_NRD_NRD_1	648	650	PF00675	0.506
CLV_NRD_NRD_1	743	745	PF00675	0.429
CLV_NRD_NRD_1	949	951	PF00675	0.625
CLV_PCSK_FUR_1	646	650	PF00082	0.604
CLV_PCSK_KEX2_1	153	155	PF00082	0.774
CLV_PCSK_KEX2_1	218	220	PF00082	0.713
CLV_PCSK_KEX2_1	264	266	PF00082	0.787
CLV_PCSK_KEX2_1	33	35	PF00082	0.570
CLV_PCSK_KEX2_1	41	43	PF00082	0.616
CLV_PCSK_KEX2_1	444	446	PF00082	0.606
CLV_PCSK_KEX2_1	51	53	PF00082	0.276
CLV_PCSK_KEX2_1	586	588	PF00082	0.486
CLV_PCSK_KEX2_1	594	596	PF00082	0.346
CLV_PCSK_KEX2_1	639	641	PF00082	0.540
CLV_PCSK_KEX2_1	645	647	PF00082	0.530
CLV_PCSK_KEX2_1	648	650	PF00082	0.525
CLV_PCSK_KEX2_1	743	745	PF00082	0.429
CLV_PCSK_KEX2_1	949	951	PF00082	0.625
CLV_PCSK_PC1ET2_1	264	266	PF00082	0.731
CLV_PCSK_PC1ET2_1	41	43	PF00082	0.619
CLV_PCSK_PC7_1	214	220	PF00082	0.623
CLV_PCSK_PC7_1	260	266	PF00082	0.794
CLV_PCSK_PC7_1	47	53	PF00082	0.624
CLV_PCSK_SKI1_1	156	160	PF00082	0.768
CLV_PCSK_SKI1_1	219	223	PF00082	0.839
CLV_PCSK_SKI1_1	594	598	PF00082	0.283
CLV_PCSK_SKI1_1	623	627	PF00082	0.367
CLV_PCSK_SKI1_1	678	682	PF00082	0.517
CLV_PCSK_SKI1_1	690	694	PF00082	0.523
CLV_PCSK_SKI1_1	707	711	PF00082	0.574
CLV_PCSK_SKI1_1	825	829	PF00082	0.556
CLV_PCSK_SKI1_1	905	909	PF00082	0.438
CLV_PCSK_SKI1_1	950	954	PF00082	0.566
DEG_APCC_DBOX_1	155	163	PF00400	0.570
DEG_SPOP_SBC_1	385	389	PF00917	0.438
DEG_SPOP_SBC_1	455	459	PF00917	0.563
DOC_CYCLIN_RxL_1	623	632	PF00134	0.403
DOC_CYCLIN_RxL_1	687	697	PF00134	0.736
DOC_CYCLIN_yCln2_LP_2	299	305	PF00134	0.491
DOC_MAPK_gen_1	271	280	PF00069	0.368
DOC_MAPK_gen_1	594	601	PF00069	0.619
DOC_MAPK_MEF2A_6	392	401	PF00069	0.436
DOC_MAPK_MEF2A_6	594	603	PF00069	0.546
DOC_PP1_RVXF_1	258	264	PF00149	0.600
DOC_PP1_RVXF_1	7	13	PF00149	0.772
DOC_PP2B_LxvP_1	299	302	PF13499	0.506
DOC_PP2B_LxvP_1	898	901	PF13499	0.729
DOC_PP2B_PxIxI_1	815	821	PF00149	0.679
DOC_USP7_MATH_1	126	130	PF00917	0.507
DOC_USP7_MATH_1	335	339	PF00917	0.488
DOC_USP7_MATH_1	408	412	PF00917	0.512
DOC_USP7_MATH_1	443	447	PF00917	0.501
DOC_USP7_MATH_1	57	61	PF00917	0.474
DOC_USP7_MATH_1	572	576	PF00917	0.733
DOC_USP7_MATH_1	698	702	PF00917	0.714
DOC_USP7_MATH_1	74	78	PF00917	0.460
DOC_USP7_MATH_1	901	905	PF00917	0.833
DOC_USP7_MATH_1	918	922	PF00917	0.636
DOC_USP7_MATH_1	942	946	PF00917	0.596
DOC_USP7_UBL2_3	31	35	PF12436	0.839
DOC_USP7_UBL2_3	37	41	PF12436	0.803
DOC_WW_Pin1_4	127	132	PF00397	0.561
DOC_WW_Pin1_4	163	168	PF00397	0.605
DOC_WW_Pin1_4	322	327	PF00397	0.578
DOC_WW_Pin1_4	504	509	PF00397	0.509
DOC_WW_Pin1_4	53	58	PF00397	0.420
DOC_WW_Pin1_4	782	787	PF00397	0.703
DOC_WW_Pin1_4	849	854	PF00397	0.715
LIG_14-3-3_CanoR_1	153	159	PF00244	0.545
LIG_14-3-3_CanoR_1	274	278	PF00244	0.575
LIG_14-3-3_CanoR_1	3	10	PF00244	0.825
LIG_14-3-3_CanoR_1	300	310	PF00244	0.513
LIG_14-3-3_CanoR_1	444	448	PF00244	0.593
LIG_14-3-3_CanoR_1	453	461	PF00244	0.543
LIG_14-3-3_CanoR_1	468	477	PF00244	0.502
LIG_14-3-3_CanoR_1	574	582	PF00244	0.736
LIG_14-3-3_CanoR_1	594	603	PF00244	0.399
LIG_14-3-3_CanoR_1	605	610	PF00244	0.488
LIG_14-3-3_CanoR_1	611	617	PF00244	0.502
LIG_14-3-3_CanoR_1	743	751	PF00244	0.714
LIG_14-3-3_CterR_2	950	955	PF00244	0.685
LIG_Actin_WH2_2	820	835	PF00022	0.748
LIG_BRCT_BRCA1_1	172	176	PF00533	0.589
LIG_BRCT_BRCA1_1	269	273	PF00533	0.579
LIG_BRCT_BRCA1_1	313	317	PF00533	0.499
LIG_CaM_IQ_9	148	163	PF13499	0.576
LIG_CSL_BTD_1	11	14	PF09270	0.610
LIG_DCNL_PONY_1	1	4	PF03556	0.748
LIG_deltaCOP1_diTrp_1	308	317	PF00928	0.496
LIG_deltaCOP1_diTrp_1	414	424	PF00928	0.396
LIG_FHA_1	296	302	PF00498	0.447
LIG_FHA_1	571	577	PF00498	0.778
LIG_FHA_1	722	728	PF00498	0.760
LIG_FHA_1	758	764	PF00498	0.614
LIG_FHA_1	79	85	PF00498	0.635
LIG_FHA_1	805	811	PF00498	0.740
LIG_FHA_1	915	921	PF00498	0.627
LIG_FHA_1	99	105	PF00498	0.373
LIG_FHA_2	401	407	PF00498	0.630
LIG_FHA_2	783	789	PF00498	0.685
LIG_FHA_2	860	866	PF00498	0.689
LIG_LIR_Gen_1	308	317	PF02991	0.496
LIG_LIR_Gen_1	414	422	PF02991	0.583
LIG_LIR_Gen_1	561	572	PF02991	0.770
LIG_LIR_Gen_1	814	823	PF02991	0.679
LIG_LIR_Gen_1	837	847	PF02991	0.680
LIG_LIR_Gen_1	883	891	PF02991	0.682
LIG_LIR_Nem_3	173	179	PF02991	0.517
LIG_LIR_Nem_3	308	313	PF02991	0.456
LIG_LIR_Nem_3	332	336	PF02991	0.570
LIG_LIR_Nem_3	414	418	PF02991	0.604
LIG_LIR_Nem_3	624	629	PF02991	0.390
LIG_LIR_Nem_3	688	692	PF02991	0.791
LIG_LIR_Nem_3	766	771	PF02991	0.714
LIG_LIR_Nem_3	814	820	PF02991	0.682
LIG_LIR_Nem_3	837	842	PF02991	0.669
LIG_LIR_Nem_3	883	889	PF02991	0.673
LIG_LYPXL_yS_3	333	336	PF13949	0.501
LIG_PCNA_yPIPBox_3	150	159	PF02747	0.514
LIG_Pex14_1	872	876	PF04695	0.676
LIG_Pex14_1	936	940	PF04695	0.775
LIG_PROFILIN_1	131	137	PF00235	0.598
LIG_REV1ctd_RIR_1	623	631	PF16727	0.436
LIG_SH2_PTP2	817	820	PF00017	0.680
LIG_SH2_SRC	201	204	PF00017	0.583
LIG_SH2_SRC	684	687	PF00017	0.702
LIG_SH2_STAP1	357	361	PF00017	0.477
LIG_SH2_STAT3	357	360	PF00017	0.475
LIG_SH2_STAT5	384	387	PF00017	0.572
LIG_SH2_STAT5	434	437	PF00017	0.535
LIG_SH2_STAT5	792	795	PF00017	0.741
LIG_SH2_STAT5	817	820	PF00017	0.680
LIG_SH2_STAT5	839	842	PF00017	0.737
LIG_SH3_3	128	134	PF00018	0.639
LIG_SH3_3	166	172	PF00018	0.520
LIG_SH3_3	328	334	PF00018	0.517
LIG_SH3_3	394	400	PF00018	0.590
LIG_SH3_3	748	754	PF00018	0.762
LIG_SUMO_SIM_par_1	161	166	PF11976	0.595
LIG_SxIP_EBH_1	592	605	PF03271	0.466
LIG_TRAF2_1	404	407	PF00917	0.553
LIG_TRAF2_1	785	788	PF00917	0.688
LIG_TRAF2_1	812	815	PF00917	0.747
LIG_TYR_ITIM	331	336	PF00017	0.630
LIG_WRC_WIRS_1	622	627	PF05994	0.513
LIG_WW_3	899	903	PF00397	0.713
MOD_CK1_1	124	130	PF00069	0.793
MOD_CK1_1	286	292	PF00069	0.543
MOD_CK1_1	325	331	PF00069	0.654
MOD_CK1_1	386	392	PF00069	0.709
MOD_CK1_1	43	49	PF00069	0.657
MOD_CK1_1	438	444	PF00069	0.707
MOD_CK1_1	454	460	PF00069	0.616
MOD_CK1_1	494	500	PF00069	0.731
MOD_CK1_1	5	11	PF00069	0.801
MOD_CK1_1	553	559	PF00069	0.524
MOD_CK1_1	56	62	PF00069	0.437
MOD_CK1_1	694	700	PF00069	0.465
MOD_CK1_1	745	751	PF00069	0.743
MOD_CK2_1	220	226	PF00069	0.829
MOD_CK2_1	315	321	PF00069	0.711
MOD_CK2_1	400	406	PF00069	0.727
MOD_CK2_1	408	414	PF00069	0.645
MOD_CK2_1	443	449	PF00069	0.609
MOD_CK2_1	56	62	PF00069	0.436
MOD_CK2_1	693	699	PF00069	0.700
MOD_CK2_1	782	788	PF00069	0.550
MOD_CK2_1	809	815	PF00069	0.605
MOD_CK2_1	859	865	PF00069	0.617
MOD_Cter_Amidation	23	26	PF01082	0.823
MOD_Cter_Amidation	643	646	PF01082	0.714
MOD_Cter_Amidation	741	744	PF01082	0.508
MOD_GlcNHglycan	105	108	PF01048	0.793
MOD_GlcNHglycan	125	129	PF01048	0.581
MOD_GlcNHglycan	172	175	PF01048	0.645
MOD_GlcNHglycan	180	183	PF01048	0.622
MOD_GlcNHglycan	19	22	PF01048	0.595
MOD_GlcNHglycan	285	288	PF01048	0.713
MOD_GlcNHglycan	294	298	PF01048	0.525
MOD_GlcNHglycan	327	330	PF01048	0.659
MOD_GlcNHglycan	4	7	PF01048	0.724
MOD_GlcNHglycan	410	413	PF01048	0.611
MOD_GlcNHglycan	42	45	PF01048	0.853
MOD_GlcNHglycan	437	440	PF01048	0.744
MOD_GlcNHglycan	453	456	PF01048	0.539
MOD_GlcNHglycan	461	464	PF01048	0.765
MOD_GlcNHglycan	471	474	PF01048	0.548
MOD_GlcNHglycan	480	483	PF01048	0.521
MOD_GlcNHglycan	516	519	PF01048	0.741
MOD_GlcNHglycan	576	579	PF01048	0.637
MOD_GlcNHglycan	663	668	PF01048	0.497
MOD_GlcNHglycan	696	699	PF01048	0.687
MOD_GlcNHglycan	700	703	PF01048	0.651
MOD_GlcNHglycan	744	747	PF01048	0.701
MOD_GlcNHglycan	755	758	PF01048	0.641
MOD_GlcNHglycan	76	79	PF01048	0.518
MOD_GlcNHglycan	843	846	PF01048	0.577
MOD_GlcNHglycan	920	923	PF01048	0.570
MOD_GlcNHglycan	927	930	PF01048	0.705
MOD_GSK3_1	114	121	PF00069	0.732
MOD_GSK3_1	142	149	PF00069	0.768
MOD_GSK3_1	170	177	PF00069	0.556
MOD_GSK3_1	233	240	PF00069	0.819
MOD_GSK3_1	243	250	PF00069	0.699
MOD_GSK3_1	286	293	PF00069	0.731
MOD_GSK3_1	311	318	PF00069	0.661
MOD_GSK3_1	325	332	PF00069	0.518
MOD_GSK3_1	383	390	PF00069	0.691
MOD_GSK3_1	42	49	PF00069	0.785
MOD_GSK3_1	443	450	PF00069	0.780
MOD_GSK3_1	451	458	PF00069	0.733
MOD_GSK3_1	490	497	PF00069	0.670
MOD_GSK3_1	53	60	PF00069	0.332
MOD_GSK3_1	570	577	PF00069	0.657
MOD_GSK3_1	694	701	PF00069	0.638
MOD_GSK3_1	74	81	PF00069	0.522
MOD_GSK3_1	753	760	PF00069	0.554
MOD_GSK3_1	778	785	PF00069	0.577
MOD_GSK3_1	914	921	PF00069	0.801
MOD_GSK3_1	98	105	PF00069	0.675
MOD_N-GLC_1	612	617	PF02516	0.580
MOD_NEK2_1	103	108	PF00069	0.672
MOD_NEK2_1	17	22	PF00069	0.559
MOD_NEK2_1	2	7	PF00069	0.797
MOD_NEK2_1	273	278	PF00069	0.734
MOD_NEK2_1	280	285	PF00069	0.619
MOD_NEK2_1	311	316	PF00069	0.599
MOD_NEK2_1	373	378	PF00069	0.693
MOD_NEK2_1	435	440	PF00069	0.742
MOD_NEK2_1	447	452	PF00069	0.592
MOD_NEK2_1	467	472	PF00069	0.578
MOD_NEK2_1	477	482	PF00069	0.604
MOD_NEK2_1	490	495	PF00069	0.665
MOD_NEK2_1	563	568	PF00069	0.676
MOD_NEK2_1	614	619	PF00069	0.656
MOD_NEK2_1	629	634	PF00069	0.358
MOD_NEK2_1	692	697	PF00069	0.699
MOD_NEK2_1	840	845	PF00069	0.558
MOD_NEK2_2	295	300	PF00069	0.524
MOD_NEK2_2	621	626	PF00069	0.436
MOD_NEK2_2	859	864	PF00069	0.604
MOD_OFUCOSY	285	290	PF10250	0.594
MOD_PIKK_1	912	918	PF00454	0.519
MOD_PK_1	142	148	PF00069	0.706
MOD_PK_1	25	31	PF00069	0.828
MOD_PKA_1	25	31	PF00069	0.828
MOD_PKA_1	33	39	PF00069	0.711
MOD_PKA_1	40	46	PF00069	0.605
MOD_PKA_1	594	600	PF00069	0.299
MOD_PKA_2	117	123	PF00069	0.766
MOD_PKA_2	2	8	PF00069	0.797
MOD_PKA_2	24	30	PF00069	0.679
MOD_PKA_2	273	279	PF00069	0.630
MOD_PKA_2	33	39	PF00069	0.675
MOD_PKA_2	443	449	PF00069	0.492
MOD_PKA_2	46	52	PF00069	0.829
MOD_PKA_2	467	473	PF00069	0.746
MOD_PKA_2	594	600	PF00069	0.338
MOD_PKA_2	60	66	PF00069	0.282
MOD_PKA_2	604	610	PF00069	0.404
MOD_PKA_2	742	748	PF00069	0.737
MOD_PKA_2	901	907	PF00069	0.740
MOD_PKB_1	40	48	PF00069	0.563
MOD_Plk_1	447	453	PF00069	0.715
MOD_Plk_1	61	67	PF00069	0.296
MOD_Plk_1	612	618	PF00069	0.578
MOD_Plk_1	714	720	PF00069	0.466
MOD_Plk_2-3	220	226	PF00069	0.751
MOD_Plk_4	273	279	PF00069	0.732
MOD_Plk_4	311	317	PF00069	0.563
MOD_Plk_4	335	341	PF00069	0.678
MOD_Plk_4	491	497	PF00069	0.748
MOD_Plk_4	563	569	PF00069	0.602
MOD_Plk_4	605	611	PF00069	0.349
MOD_Plk_4	867	873	PF00069	0.486
MOD_ProDKin_1	127	133	PF00069	0.713
MOD_ProDKin_1	163	169	PF00069	0.775
MOD_ProDKin_1	322	328	PF00069	0.737
MOD_ProDKin_1	504	510	PF00069	0.641
MOD_ProDKin_1	53	59	PF00069	0.420
MOD_ProDKin_1	782	788	PF00069	0.633
MOD_ProDKin_1	849	855	PF00069	0.646
TRG_DiLeu_BaEn_1	815	820	PF01217	0.602
TRG_DiLeu_BaEn_2	307	313	PF01217	0.724
TRG_DiLeu_BaLyEn_6	584	589	PF01217	0.701
TRG_ENDOCYTIC_2	333	336	PF00928	0.628
TRG_ENDOCYTIC_2	370	373	PF00928	0.731
TRG_ENDOCYTIC_2	622	625	PF00928	0.392
TRG_ENDOCYTIC_2	817	820	PF00928	0.599
TRG_ENDOCYTIC_2	839	842	PF00928	0.679
TRG_ER_diArg_1	153	156	PF00400	0.727
TRG_ER_diArg_1	586	588	PF00400	0.709
TRG_ER_diArg_1	593	595	PF00400	0.587
TRG_ER_diArg_1	638	640	PF00400	0.733
TRG_ER_diArg_1	645	648	PF00400	0.689
TRG_ER_diArg_1	831	834	PF00400	0.693
TRG_ER_diArg_1	948	950	PF00400	0.718
TRG_NLS_Bipartite_1	25	44	PF00514	0.674
TRG_NLS_MonoExtN_4	31	38	PF00514	0.753
TRG_Pf-PMV_PEXEL_1	156	161	PF00026	0.727
TRG_Pf-PMV_PEXEL_1	445	449	PF00026	0.710

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IL01	Leptomonas seymouri	35%	100%
A0A3S5H6V1	Leishmania donovani	86%	99%
A4H857	Leishmania braziliensis	72%	99%
A4HWI3	Leishmania infantum	86%	99%
Q4QF99	Leishmania major	82%	99%