UDP-galactose transporter

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

nucleotide-sugar transporter, putative

Species:

Leishmania mexicana

UniProt:

E9AQ83_LEIMU

TriTrypDb:

LmxM.15.0840

Length:

409

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

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Cellular components
Term	Name	Level	Count
GO:0000139	Golgi membrane	5	9
GO:0016020	membrane	2	9
GO:0031090	organelle membrane	3	9
GO:0098588	bounding membrane of organelle	4	9
GO:0110165	cellular anatomical entity	1	9

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Expansion

Sequence features

E9AQ83

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQ83

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	6
GO:0008643	carbohydrate transport	5	6
GO:0051179	localization	1	6
GO:0051234	establishment of localization	2	6
GO:0071702	organic substance transport	4	6

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Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	9
GO:0005338	nucleotide-sugar transmembrane transporter activity	4	9
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	5	9
GO:0015932	nucleobase-containing compound transmembrane transporter activity	3	9
GO:0022857	transmembrane transporter activity	2	9
GO:1901505	carbohydrate derivative transmembrane transporter activity	3	9

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	141	143	PF00675	0.216
CLV_NRD_NRD_1	202	204	PF00675	0.240
CLV_PCSK_KEX2_1	141	143	PF00082	0.216
CLV_PCSK_SKI1_1	134	138	PF00082	0.240
CLV_PCSK_SKI1_1	184	188	PF00082	0.214
CLV_PCSK_SKI1_1	230	234	PF00082	0.320
CLV_PCSK_SKI1_1	405	409	PF00082	0.367
DEG_SPOP_SBC_1	292	296	PF00917	0.296
DOC_CYCLIN_RxL_1	131	138	PF00134	0.542
DOC_CYCLIN_RxL_1	181	188	PF00134	0.214

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6R3	Leptomonas seymouri	61%	100%
A0A0N0P7L9	Leptomonas seymouri	24%	93%
A0A0S4JKR6	Bodo saltans	44%	100%
A0A1X0NTU7	Trypanosomatidae	44%	100%
A0A3S7WTI2	Leishmania donovani	81%	89%
A0A422NRC3	Trypanosoma rangeli	43%	100%
A4H9E4	Leishmania braziliensis	23%	73%
A4HWI2	Leishmania infantum	80%	89%
A4IHW3	Xenopus tropicalis	24%	100%
B8A7Q8	Oryza sativa subsp. indica	25%	100%

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