Tb-292 membrane associated protein-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

tb-292 membrane associated protein-like protein

Species:

Leishmania mexicana

UniProt:

E9AQ46_LEIMU

TriTrypDb:

LmxM.15.0440

Length:

1187

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQ46

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQ46

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	65	69	PF00656	0.678
CLV_NRD_NRD_1	132	134	PF00675	0.668
CLV_NRD_NRD_1	50	52	PF00675	0.682
CLV_PCSK_KEX2_1	132	134	PF00082	0.668
CLV_PCSK_KEX2_1	94	96	PF00082	0.682
CLV_PCSK_PC1ET2_1	94	96	PF00082	0.682
CLV_PCSK_PC7_1	90	96	PF00082	0.666
DEG_SCF_FBW7_2	1025	1031	PF00400	0.681
DEG_SCF_FBW7_2	1060	1066	PF00400	0.685
DEG_SCF_FBW7_2	1095	1101	PF00400	0.699
DEG_SCF_FBW7_2	1129	1136	PF00400	0.691
DEG_SCF_FBW7_2	1165	1171	PF00400	0.686
DEG_SCF_FBW7_2	220	226	PF00400	0.680
DEG_SCF_FBW7_2	254	261	PF00400	0.695
DEG_SCF_FBW7_2	289	296	PF00400	0.701
DEG_SCF_FBW7_2	324	331	PF00400	0.704
DEG_SCF_FBW7_2	359	366	PF00400	0.689
DEG_SCF_FBW7_2	394	401	PF00400	0.695
DEG_SCF_FBW7_2	429	436	PF00400	0.675
DEG_SCF_FBW7_2	465	471	PF00400	0.699
DEG_SCF_FBW7_2	499	506	PF00400	0.703
DEG_SCF_FBW7_2	535	541	PF00400	0.690
DEG_SCF_FBW7_2	605	611	PF00400	0.706
DEG_SCF_FBW7_2	640	646	PF00400	0.701
DEG_SCF_FBW7_2	674	681	PF00400	0.689
DEG_SCF_FBW7_2	710	716	PF00400	0.696
DEG_SCF_FBW7_2	745	751	PF00400	0.698
DEG_SCF_FBW7_2	779	786	PF00400	0.707
DEG_SCF_FBW7_2	815	821	PF00400	0.703
DEG_SCF_FBW7_2	849	856	PF00400	0.700
DEG_SCF_FBW7_2	884	891	PF00400	0.701
DEG_SCF_FBW7_2	955	961	PF00400	0.701
DEG_SCF_FBW7_2	989	996	PF00400	0.710
DEG_SPOP_SBC_1	112	116	PF00917	0.675
DEG_SPOP_SBC_1	77	81	PF00917	0.691
DOC_CKS1_1	1025	1030	PF01111	0.679
DOC_CKS1_1	1060	1065	PF01111	0.683
DOC_CKS1_1	1095	1100	PF01111	0.697
DOC_CKS1_1	1130	1135	PF01111	0.694
DOC_CKS1_1	1165	1170	PF01111	0.685
DOC_CKS1_1	220	225	PF01111	0.679
DOC_CKS1_1	255	260	PF01111	0.699
DOC_CKS1_1	290	295	PF01111	0.704
DOC_CKS1_1	325	330	PF01111	0.706
DOC_CKS1_1	360	365	PF01111	0.693
DOC_CKS1_1	395	400	PF01111	0.695
DOC_CKS1_1	430	435	PF01111	0.684
DOC_CKS1_1	465	470	PF01111	0.698
DOC_CKS1_1	500	505	PF01111	0.708
DOC_CKS1_1	535	540	PF01111	0.688
DOC_CKS1_1	605	610	PF01111	0.705
DOC_CKS1_1	640	645	PF01111	0.699
DOC_CKS1_1	675	680	PF01111	0.695
DOC_CKS1_1	710	715	PF01111	0.694
DOC_CKS1_1	745	750	PF01111	0.697
DOC_CKS1_1	780	785	PF01111	0.709
DOC_CKS1_1	815	820	PF01111	0.703
DOC_CKS1_1	850	855	PF01111	0.702
DOC_CKS1_1	885	890	PF01111	0.706
DOC_CKS1_1	955	960	PF01111	0.700
DOC_CKS1_1	990	995	PF01111	0.711
DOC_CYCLIN_yCln2_LP_2	566	572	PF00134	0.705
DOC_CYCLIN_yCln2_LP_2	916	922	PF00134	0.702
DOC_MAPK_MEF2A_6	98	107	PF00069	0.685
DOC_PP2B_PxIxI_1	102	108	PF00149	0.692
DOC_USP7_MATH_1	1000	1004	PF00917	0.697
DOC_USP7_MATH_1	1035	1039	PF00917	0.692
DOC_USP7_MATH_1	1070	1074	PF00917	0.701
DOC_USP7_MATH_1	1105	1109	PF00917	0.683
DOC_USP7_MATH_1	112	116	PF00917	0.675
DOC_USP7_MATH_1	1140	1144	PF00917	0.688
DOC_USP7_MATH_1	1175	1179	PF00917	0.661
DOC_USP7_MATH_1	142	146	PF00917	0.623
DOC_USP7_MATH_1	230	234	PF00917	0.653
DOC_USP7_MATH_1	265	269	PF00917	0.697
DOC_USP7_MATH_1	300	304	PF00917	0.677
DOC_USP7_MATH_1	335	339	PF00917	0.685
DOC_USP7_MATH_1	370	374	PF00917	0.690
DOC_USP7_MATH_1	405	409	PF00917	0.699
DOC_USP7_MATH_1	440	444	PF00917	0.681
DOC_USP7_MATH_1	475	479	PF00917	0.697
DOC_USP7_MATH_1	510	514	PF00917	0.688
DOC_USP7_MATH_1	545	549	PF00917	0.694
DOC_USP7_MATH_1	580	584	PF00917	0.683
DOC_USP7_MATH_1	615	619	PF00917	0.699
DOC_USP7_MATH_1	650	654	PF00917	0.697
DOC_USP7_MATH_1	685	689	PF00917	0.706
DOC_USP7_MATH_1	69	73	PF00917	0.690
DOC_USP7_MATH_1	720	724	PF00917	0.681
DOC_USP7_MATH_1	755	759	PF00917	0.698
DOC_USP7_MATH_1	790	794	PF00917	0.701
DOC_USP7_MATH_1	825	829	PF00917	0.687
DOC_USP7_MATH_1	860	864	PF00917	0.697
DOC_USP7_MATH_1	895	899	PF00917	0.701
DOC_USP7_MATH_1	930	934	PF00917	0.694
DOC_USP7_MATH_1	965	969	PF00917	0.695
DOC_WW_Pin1_4	1024	1029	PF00397	0.672
DOC_WW_Pin1_4	1059	1064	PF00397	0.673
DOC_WW_Pin1_4	1094	1099	PF00397	0.698
DOC_WW_Pin1_4	1129	1134	PF00397	0.688
DOC_WW_Pin1_4	113	118	PF00397	0.550
DOC_WW_Pin1_4	1164	1169	PF00397	0.680
DOC_WW_Pin1_4	1179	1184	PF00397	0.516
DOC_WW_Pin1_4	219	224	PF00397	0.677
DOC_WW_Pin1_4	254	259	PF00397	0.637
DOC_WW_Pin1_4	289	294	PF00397	0.701
DOC_WW_Pin1_4	324	329	PF00397	0.678
DOC_WW_Pin1_4	359	364	PF00397	0.688
DOC_WW_Pin1_4	394	399	PF00397	0.693
DOC_WW_Pin1_4	429	434	PF00397	0.669
DOC_WW_Pin1_4	464	469	PF00397	0.696
DOC_WW_Pin1_4	499	504	PF00397	0.701
DOC_WW_Pin1_4	534	539	PF00397	0.687
DOC_WW_Pin1_4	604	609	PF00397	0.701
DOC_WW_Pin1_4	639	644	PF00397	0.698
DOC_WW_Pin1_4	674	679	PF00397	0.683
DOC_WW_Pin1_4	709	714	PF00397	0.693
DOC_WW_Pin1_4	73	78	PF00397	0.693
DOC_WW_Pin1_4	744	749	PF00397	0.694
DOC_WW_Pin1_4	779	784	PF00397	0.706
DOC_WW_Pin1_4	814	819	PF00397	0.705
DOC_WW_Pin1_4	849	854	PF00397	0.697
DOC_WW_Pin1_4	884	889	PF00397	0.698
DOC_WW_Pin1_4	954	959	PF00397	0.699
DOC_WW_Pin1_4	989	994	PF00397	0.708
DOC_WW_Pin1_4	99	104	PF00397	0.679
LIG_14-3-3_CanoR_1	70	77	PF00244	0.693
LIG_APCC_ABBAyCdc20_2	192	198	PF00400	0.651
LIG_BRCT_BRCA1_1	164	168	PF00533	0.664
LIG_FHA_1	144	150	PF00498	0.670
LIG_FHA_1	186	192	PF00498	0.630
LIG_FHA_1	38	44	PF00498	0.684
LIG_FHA_2	1025	1031	PF00498	0.681
LIG_FHA_2	104	110	PF00498	0.694
LIG_FHA_2	1060	1066	PF00498	0.685
LIG_FHA_2	1095	1101	PF00498	0.699
LIG_FHA_2	1130	1136	PF00498	0.696
LIG_FHA_2	1165	1171	PF00498	0.686
LIG_FHA_2	139	145	PF00498	0.670
LIG_FHA_2	220	226	PF00498	0.680
LIG_FHA_2	255	261	PF00498	0.699
LIG_FHA_2	290	296	PF00498	0.702
LIG_FHA_2	325	331	PF00498	0.782
LIG_FHA_2	360	366	PF00498	0.692
LIG_FHA_2	395	401	PF00498	0.697
LIG_FHA_2	430	436	PF00498	0.684
LIG_FHA_2	465	471	PF00498	0.699
LIG_FHA_2	500	506	PF00498	0.708
LIG_FHA_2	535	541	PF00498	0.690
LIG_FHA_2	56	62	PF00498	0.695
LIG_FHA_2	605	611	PF00498	0.706
LIG_FHA_2	640	646	PF00498	0.701
LIG_FHA_2	675	681	PF00498	0.698
LIG_FHA_2	710	716	PF00498	0.696
LIG_FHA_2	745	751	PF00498	0.698
LIG_FHA_2	780	786	PF00498	0.710
LIG_FHA_2	815	821	PF00498	0.703
LIG_FHA_2	850	856	PF00498	0.703
LIG_FHA_2	885	891	PF00498	0.707
LIG_FHA_2	955	961	PF00498	0.701
LIG_FHA_2	990	996	PF00498	0.712
LIG_PDZ_Class_2	1182	1187	PF00595	0.636
LIG_SH2_CRK	187	191	PF00017	0.636
LIG_SH2_STAP1	187	191	PF00017	0.694
LIG_SH2_STAT5	187	190	PF00017	0.633
LIG_SH2_STAT5	88	91	PF00017	0.672
LIG_SUMO_SIM_anti_2	32	47	PF11976	0.690
MOD_CDK_SPK_2	1179	1184	PF00069	0.647
MOD_CK1_1	1024	1030	PF00069	0.673
MOD_CK1_1	1059	1065	PF00069	0.677
MOD_CK1_1	1094	1100	PF00069	0.697
MOD_CK1_1	115	121	PF00069	0.675
MOD_CK1_1	1164	1170	PF00069	0.681
MOD_CK1_1	155	161	PF00069	0.679
MOD_CK1_1	219	225	PF00069	0.677
MOD_CK1_1	29	35	PF00069	0.700
MOD_CK1_1	464	470	PF00069	0.696
MOD_CK1_1	534	540	PF00069	0.688
MOD_CK1_1	604	610	PF00069	0.702
MOD_CK1_1	639	645	PF00069	0.698
MOD_CK1_1	709	715	PF00069	0.694
MOD_CK1_1	71	77	PF00069	0.692
MOD_CK1_1	744	750	PF00069	0.695
MOD_CK1_1	78	84	PF00069	0.619
MOD_CK1_1	814	820	PF00069	0.703
MOD_CK1_1	954	960	PF00069	0.700
MOD_CK2_1	1175	1181	PF00069	0.660
MOD_CK2_1	138	144	PF00069	0.672
MOD_CK2_1	32	38	PF00069	0.696
MOD_CK2_1	55	61	PF00069	0.696
MOD_GlcNHglycan	1002	1005	PF01048	0.703
MOD_GlcNHglycan	1037	1040	PF01048	0.704
MOD_GlcNHglycan	1072	1075	PF01048	0.707
MOD_GlcNHglycan	1107	1110	PF01048	0.693
MOD_GlcNHglycan	1142	1145	PF01048	0.696
MOD_GlcNHglycan	1177	1180	PF01048	0.662
MOD_GlcNHglycan	165	168	PF01048	0.693
MOD_GlcNHglycan	169	172	PF01048	0.638
MOD_GlcNHglycan	175	179	PF01048	0.559
MOD_GlcNHglycan	232	235	PF01048	0.689
MOD_GlcNHglycan	267	270	PF01048	0.699
MOD_GlcNHglycan	302	305	PF01048	0.686
MOD_GlcNHglycan	337	340	PF01048	0.697
MOD_GlcNHglycan	372	375	PF01048	0.701
MOD_GlcNHglycan	407	410	PF01048	0.703
MOD_GlcNHglycan	442	445	PF01048	0.694
MOD_GlcNHglycan	477	480	PF01048	0.703
MOD_GlcNHglycan	512	515	PF01048	0.680
MOD_GlcNHglycan	547	550	PF01048	0.707
MOD_GlcNHglycan	582	585	PF01048	0.696
MOD_GlcNHglycan	617	620	PF01048	0.705
MOD_GlcNHglycan	652	655	PF01048	0.697
MOD_GlcNHglycan	687	690	PF01048	0.705
MOD_GlcNHglycan	71	74	PF01048	0.697
MOD_GlcNHglycan	722	725	PF01048	0.691
MOD_GlcNHglycan	757	760	PF01048	0.710
MOD_GlcNHglycan	792	795	PF01048	0.703
MOD_GlcNHglycan	827	830	PF01048	0.693
MOD_GlcNHglycan	862	865	PF01048	0.708
MOD_GlcNHglycan	897	900	PF01048	0.709
MOD_GlcNHglycan	932	935	PF01048	0.698
MOD_GlcNHglycan	967	970	PF01048	0.699
MOD_GSK3_1	111	118	PF00069	0.564
MOD_GSK3_1	1175	1182	PF00069	0.659
MOD_GSK3_1	138	145	PF00069	0.612
MOD_GSK3_1	155	162	PF00069	0.613
MOD_GSK3_1	163	170	PF00069	0.571
MOD_GSK3_1	174	181	PF00069	0.499
MOD_GSK3_1	210	217	PF00069	0.700
MOD_GSK3_1	26	33	PF00069	0.701
MOD_GSK3_1	37	44	PF00069	0.588
MOD_GSK3_1	60	67	PF00069	0.692
MOD_GSK3_1	68	75	PF00069	0.621
MOD_GSK3_1	78	85	PF00069	0.523
MOD_GSK3_1	99	106	PF00069	0.682
MOD_NEK2_1	1021	1026	PF00069	0.671
MOD_NEK2_1	1056	1061	PF00069	0.671
MOD_NEK2_1	1091	1096	PF00069	0.702
MOD_NEK2_1	1161	1166	PF00069	0.683
MOD_NEK2_1	174	179	PF00069	0.657
MOD_NEK2_1	461	466	PF00069	0.687
MOD_NEK2_1	531	536	PF00069	0.687
MOD_NEK2_1	601	606	PF00069	0.698
MOD_NEK2_1	636	641	PF00069	0.697
MOD_NEK2_1	706	711	PF00069	0.700
MOD_NEK2_1	741	746	PF00069	0.696
MOD_NEK2_1	811	816	PF00069	0.707
MOD_NEK2_1	84	89	PF00069	0.678
MOD_NEK2_1	951	956	PF00069	0.700
MOD_PIKK_1	115	121	PF00454	0.675
MOD_PIKK_1	26	32	PF00454	0.652
MOD_PIKK_1	88	94	PF00454	0.664
MOD_PKA_2	152	158	PF00069	0.624
MOD_PKA_2	69	75	PF00069	0.693
MOD_Plk_1	1021	1027	PF00069	0.674
MOD_Plk_1	1056	1062	PF00069	0.674
MOD_Plk_1	1091	1097	PF00069	0.701
MOD_Plk_1	1161	1167	PF00069	0.681
MOD_Plk_1	143	149	PF00069	0.668
MOD_Plk_1	155	161	PF00069	0.603
MOD_Plk_1	461	467	PF00069	0.691
MOD_Plk_1	531	537	PF00069	0.688
MOD_Plk_1	60	66	PF00069	0.697
MOD_Plk_1	601	607	PF00069	0.700
MOD_Plk_1	636	642	PF00069	0.698
MOD_Plk_1	706	712	PF00069	0.701
MOD_Plk_1	741	747	PF00069	0.699
MOD_Plk_1	811	817	PF00069	0.706
MOD_Plk_1	951	957	PF00069	0.702
MOD_Plk_4	186	192	PF00069	0.630
MOD_Plk_4	41	47	PF00069	0.683
MOD_Plk_4	84	90	PF00069	0.680
MOD_ProDKin_1	1024	1030	PF00069	0.673
MOD_ProDKin_1	1059	1065	PF00069	0.677
MOD_ProDKin_1	1094	1100	PF00069	0.697
MOD_ProDKin_1	1129	1135	PF00069	0.688
MOD_ProDKin_1	113	119	PF00069	0.549
MOD_ProDKin_1	1164	1170	PF00069	0.681
MOD_ProDKin_1	1179	1185	PF00069	0.513
MOD_ProDKin_1	219	225	PF00069	0.677
MOD_ProDKin_1	254	260	PF00069	0.636
MOD_ProDKin_1	289	295	PF00069	0.702
MOD_ProDKin_1	324	330	PF00069	0.679
MOD_ProDKin_1	359	365	PF00069	0.690
MOD_ProDKin_1	394	400	PF00069	0.694
MOD_ProDKin_1	429	435	PF00069	0.673
MOD_ProDKin_1	464	470	PF00069	0.696
MOD_ProDKin_1	499	505	PF00069	0.702
MOD_ProDKin_1	534	540	PF00069	0.688
MOD_ProDKin_1	604	610	PF00069	0.702
MOD_ProDKin_1	639	645	PF00069	0.698
MOD_ProDKin_1	674	680	PF00069	0.686
MOD_ProDKin_1	709	715	PF00069	0.694
MOD_ProDKin_1	73	79	PF00069	0.693
MOD_ProDKin_1	744	750	PF00069	0.695
MOD_ProDKin_1	779	785	PF00069	0.706
MOD_ProDKin_1	814	820	PF00069	0.703
MOD_ProDKin_1	849	855	PF00069	0.700
MOD_ProDKin_1	884	890	PF00069	0.699
MOD_ProDKin_1	954	960	PF00069	0.700
MOD_ProDKin_1	989	995	PF00069	0.708
MOD_ProDKin_1	99	105	PF00069	0.683
TRG_DiLeu_BaEn_1	144	149	PF01217	0.670
TRG_DiLeu_BaLyEn_6	17	22	PF01217	0.690
TRG_ENDOCYTIC_2	187	190	PF00928	0.583
TRG_ER_diArg_1	131	133	PF00400	0.655

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H7T4	Leishmania braziliensis	30%	95%