Cytochrome b5 heme-binding domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

cytochrome b5-like Heme/Steroid binding domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9AQ17_LEIMU

TriTrypDb:

LmxM.15.0190

Length:

163


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10
GO:0005783	endoplasmic reticulum	5	1
GO:0012505	endomembrane system	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

E9AQ17

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQ17


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	156	158	PF00082	0.295
CLV_PCSK_KEX2_1	66	68	PF00082	0.170
CLV_PCSK_PC1ET2_1	156	158	PF00082	0.295
CLV_PCSK_PC1ET2_1	66	68	PF00082	0.170
CLV_PCSK_SKI1_1	10	14	PF00082	0.672
DOC_MAPK_gen_1	66	73	PF00069	0.474
DOC_MAPK_MEF2A_6	66	75	PF00069	0.486
DOC_PP1_RVXF_1	30	36	PF00149	0.311
DOC_USP7_MATH_1	4	8	PF00917	0.354
DOC_USP7_UBL2_3	152	156	PF12436	0.555
LIG_14-3-3_CanoR_1	157	162	PF00244	0.602
LIG_14-3-3_CanoR_1	53	58	PF00244	0.485
LIG_BIR_II_1	1	5	PF00653	0.480
LIG_deltaCOP1_diTrp_1	132	137	PF00928	0.471
LIG_FHA_2	127	133	PF00498	0.406
LIG_FHA_2	54	60	PF00498	0.428
LIG_Integrin_RGD_1	46	48	PF01839	0.273
LIG_LIR_Apic_2	83	89	PF02991	0.448
LIG_LIR_Gen_1	118	127	PF02991	0.406
LIG_LIR_Gen_1	90	97	PF02991	0.472
LIG_LIR_Nem_3	118	122	PF02991	0.398
LIG_LIR_Nem_3	139	144	PF02991	0.447
LIG_LIR_Nem_3	90	96	PF02991	0.463
LIG_LYPXL_yS_3	141	144	PF13949	0.458
LIG_Pex14_1	133	137	PF04695	0.429
LIG_SH2_STAP1	93	97	PF00017	0.514
LIG_SH2_STAT5	55	58	PF00017	0.448
LIG_SH3_3	86	92	PF00018	0.464
LIG_TRAF2_1	56	59	PF00917	0.410
LIG_UBA3_1	29	36	PF00899	0.454
MOD_CK1_1	2	8	PF00069	0.478
MOD_CK2_1	126	132	PF00069	0.466
MOD_CK2_1	53	59	PF00069	0.431
MOD_Cter_Amidation	64	67	PF01082	0.279
MOD_GlcNHglycan	6	9	PF01048	0.668
MOD_GlcNHglycan	93	96	PF01048	0.332
MOD_N-GLC_1	2	7	PF02516	0.517
MOD_N-GLC_1	80	85	PF02516	0.275
MOD_Plk_1	117	123	PF00069	0.399
MOD_Plk_1	80	86	PF00069	0.502
MOD_Plk_4	13	19	PF00069	0.279
MOD_SUMO_rev_2	58	68	PF00179	0.475
TRG_ENDOCYTIC_2	141	144	PF00928	0.426
TRG_ENDOCYTIC_2	93	96	PF00928	0.433
TRG_ER_diArg_1	38	41	PF00400	0.550


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8C7	Leptomonas seymouri	39%	100%
A0A0N1I2M9	Leptomonas seymouri	66%	100%
A0A0S4IM89	Bodo saltans	38%	100%
A0A0S4IWT4	Bodo saltans	29%	95%
A0A0S4KHZ8	Bodo saltans	52%	100%
A0A1X0NM31	Trypanosomatidae	35%	100%
A0A1X0NTL9	Trypanosomatidae	58%	100%
A0A3Q8IGX1	Leishmania donovani	40%	100%
A0A3R7L838	Trypanosoma rangeli	35%	100%
A0A3R7RC54	Trypanosoma rangeli	38%	91%
A0A3S7WTB2	Leishmania donovani	94%	100%
A0A422NSD0	Trypanosoma rangeli	54%	100%
A4H7Y9	Leishmania braziliensis	79%	100%
A4HB24	Leishmania braziliensis	38%	92%
A4HQJ0	Leishmania braziliensis	39%	100%
A4HWB7	Leishmania infantum	95%	100%
C9ZNV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
E9AHZ9	Leishmania infantum	40%	100%
E9AUA3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
O13995	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	98%
Q4QFG4	Leishmania major	94%	100%
Q7YZW5	Caenorhabditis elegans	32%	89%
V5DM24	Trypanosoma cruzi	33%	91%