Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AQ16_LEIMU

TriTrypDb:

LmxM.15.0185

Length:

584

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQ16

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQ16

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	488	492	PF00656	0.391
CLV_C14_Caspase3-7	546	550	PF00656	0.568
CLV_MEL_PAP_1	404	410	PF00089	0.538
CLV_NRD_NRD_1	275	277	PF00675	0.750
CLV_NRD_NRD_1	320	322	PF00675	0.593
CLV_NRD_NRD_1	392	394	PF00675	0.672
CLV_NRD_NRD_1	475	477	PF00675	0.672
CLV_NRD_NRD_1	551	553	PF00675	0.534
CLV_NRD_NRD_1	579	581	PF00675	0.674
CLV_PCSK_KEX2_1	275	277	PF00082	0.750
CLV_PCSK_KEX2_1	319	321	PF00082	0.600
CLV_PCSK_KEX2_1	475	477	PF00082	0.672
CLV_PCSK_KEX2_1	551	553	PF00082	0.534
CLV_PCSK_KEX2_1	579	581	PF00082	0.713
CLV_PCSK_SKI1_1	403	407	PF00082	0.532
CLV_PCSK_SKI1_1	498	502	PF00082	0.567
DEG_Nend_UBRbox_2	1	3	PF02207	0.606
DEG_SPOP_SBC_1	93	97	PF00917	0.718
DOC_CKS1_1	1	6	PF01111	0.629
DOC_CYCLIN_RxL_1	400	410	PF00134	0.532
DOC_MAPK_gen_1	401	408	PF00069	0.511
DOC_MAPK_gen_1	548	556	PF00069	0.520
DOC_MAPK_MEF2A_6	102	111	PF00069	0.610
DOC_MAPK_MEF2A_6	401	408	PF00069	0.603
DOC_MAPK_NFAT4_5	401	409	PF00069	0.539
DOC_PP2B_LxvP_1	518	521	PF13499	0.667
DOC_PP2B_LxvP_1	556	559	PF13499	0.612
DOC_USP7_MATH_1	101	105	PF00917	0.560
DOC_USP7_MATH_1	130	134	PF00917	0.626
DOC_USP7_MATH_1	136	140	PF00917	0.613
DOC_USP7_MATH_1	142	146	PF00917	0.562
DOC_USP7_MATH_1	175	179	PF00917	0.714
DOC_USP7_MATH_1	21	25	PF00917	0.649
DOC_USP7_MATH_1	266	270	PF00917	0.570
DOC_USP7_MATH_1	27	31	PF00917	0.624
DOC_USP7_MATH_1	298	302	PF00917	0.516
DOC_USP7_MATH_1	325	329	PF00917	0.558
DOC_USP7_MATH_1	345	349	PF00917	0.701
DOC_USP7_MATH_1	362	366	PF00917	0.516
DOC_USP7_MATH_1	455	459	PF00917	0.526
DOC_USP7_MATH_1	465	469	PF00917	0.581
DOC_USP7_MATH_1	52	56	PF00917	0.547
DOC_USP7_MATH_1	521	525	PF00917	0.621
DOC_USP7_MATH_1	528	532	PF00917	0.627
DOC_USP7_MATH_1	80	84	PF00917	0.697
DOC_USP7_MATH_1	87	91	PF00917	0.605
DOC_WW_Pin1_4	164	169	PF00397	0.680
DOC_WW_Pin1_4	201	206	PF00397	0.643
DOC_WW_Pin1_4	224	229	PF00397	0.696
DOC_WW_Pin1_4	231	236	PF00397	0.615
DOC_WW_Pin1_4	267	272	PF00397	0.690
DOC_WW_Pin1_4	288	293	PF00397	0.672
DOC_WW_Pin1_4	481	486	PF00397	0.568
DOC_WW_Pin1_4	507	512	PF00397	0.585
DOC_WW_Pin1_4	58	63	PF00397	0.718
DOC_WW_Pin1_4	83	88	PF00397	0.722
LIG_14-3-3_CanoR_1	138	146	PF00244	0.591
LIG_14-3-3_CanoR_1	171	175	PF00244	0.653
LIG_14-3-3_CanoR_1	275	283	PF00244	0.609
LIG_14-3-3_CanoR_1	438	443	PF00244	0.386
LIG_14-3-3_CanoR_1	454	464	PF00244	0.499
LIG_14-3-3_CanoR_1	529	534	PF00244	0.638
LIG_14-3-3_CanoR_1	551	555	PF00244	0.620
LIG_14-3-3_CanoR_1	561	566	PF00244	0.668
LIG_Actin_WH2_2	392	409	PF00022	0.551
LIG_CtBP_PxDLS_1	486	490	PF00389	0.480
LIG_FHA_1	154	160	PF00498	0.696
LIG_FHA_1	201	207	PF00498	0.632
LIG_FHA_1	23	29	PF00498	0.791
LIG_FHA_1	280	286	PF00498	0.721
LIG_FHA_1	325	331	PF00498	0.561
LIG_FHA_1	382	388	PF00498	0.602
LIG_FHA_1	482	488	PF00498	0.468
LIG_FHA_1	95	101	PF00498	0.653
LIG_FHA_2	289	295	PF00498	0.606
LIG_FHA_2	390	396	PF00498	0.400
LIG_GBD_Chelix_1	307	315	PF00786	0.453
LIG_GBD_Chelix_1	493	501	PF00786	0.465
LIG_Integrin_RGD_1	449	451	PF01839	0.503
LIG_LIR_Nem_3	237	241	PF02991	0.710
LIG_LYPXL_yS_3	522	525	PF13949	0.531
LIG_MYND_3	70	74	PF01753	0.618
LIG_NRBOX	401	407	PF00104	0.657
LIG_NRBOX	492	498	PF00104	0.475
LIG_SH2_NCK_1	283	287	PF00017	0.541
LIG_SH2_STAT3	41	44	PF00017	0.647
LIG_SH2_STAT5	15	18	PF00017	0.554
LIG_SH2_STAT5	499	502	PF00017	0.504
LIG_SH3_1	552	558	PF00018	0.765
LIG_SH3_3	199	205	PF00018	0.632
LIG_SH3_3	225	231	PF00018	0.671
LIG_SH3_3	520	526	PF00018	0.759
LIG_SH3_3	552	558	PF00018	0.794
LIG_SH3_3	57	63	PF00018	0.700
LIG_SH3_3	65	71	PF00018	0.695
LIG_SUMO_SIM_anti_2	120	128	PF11976	0.529
LIG_SUMO_SIM_anti_2	490	498	PF11976	0.378
LIG_SUMO_SIM_par_1	241	247	PF11976	0.672
LIG_SUMO_SIM_par_1	334	340	PF11976	0.439
LIG_SUMO_SIM_par_1	484	492	PF11976	0.414
LIG_TYR_ITIM	520	525	PF00017	0.528
MOD_CDK_SPxxK_3	164	171	PF00069	0.669
MOD_CK1_1	204	210	PF00069	0.735
MOD_CK1_1	229	235	PF00069	0.669
MOD_CK1_1	250	256	PF00069	0.678
MOD_CK1_1	269	275	PF00069	0.715
MOD_CK1_1	277	283	PF00069	0.642
MOD_CK1_1	284	290	PF00069	0.596
MOD_CK1_1	328	334	PF00069	0.468
MOD_CK1_1	468	474	PF00069	0.660
MOD_CK1_1	479	485	PF00069	0.566
MOD_CK1_1	492	498	PF00069	0.373
MOD_CK1_1	532	538	PF00069	0.630
MOD_CK1_1	61	67	PF00069	0.694
MOD_CK1_1	83	89	PF00069	0.804
MOD_CK1_1	92	98	PF00069	0.651
MOD_CK2_1	175	181	PF00069	0.697
MOD_CK2_1	207	213	PF00069	0.695
MOD_CK2_1	345	351	PF00069	0.707
MOD_CK2_1	455	461	PF00069	0.520
MOD_Cter_Amidation	549	552	PF01082	0.514
MOD_GlcNHglycan	134	137	PF01048	0.634
MOD_GlcNHglycan	172	175	PF01048	0.676
MOD_GlcNHglycan	183	186	PF01048	0.586
MOD_GlcNHglycan	29	32	PF01048	0.610
MOD_GlcNHglycan	342	345	PF01048	0.520
MOD_GlcNHglycan	35	38	PF01048	0.686
MOD_GlcNHglycan	427	431	PF01048	0.541
MOD_GlcNHglycan	567	570	PF01048	0.720
MOD_GlcNHglycan	82	85	PF01048	0.736
MOD_GlcNHglycan	91	94	PF01048	0.676
MOD_GlcNHglycan	97	100	PF01048	0.567
MOD_GSK3_1	132	139	PF00069	0.606
MOD_GSK3_1	192	199	PF00069	0.734
MOD_GSK3_1	200	207	PF00069	0.635
MOD_GSK3_1	222	229	PF00069	0.712
MOD_GSK3_1	230	237	PF00069	0.623
MOD_GSK3_1	246	253	PF00069	0.585
MOD_GSK3_1	266	273	PF00069	0.746
MOD_GSK3_1	275	282	PF00069	0.631
MOD_GSK3_1	284	291	PF00069	0.534
MOD_GSK3_1	29	36	PF00069	0.672
MOD_GSK3_1	324	331	PF00069	0.573
MOD_GSK3_1	455	462	PF00069	0.589
MOD_GSK3_1	464	471	PF00069	0.582
MOD_GSK3_1	477	484	PF00069	0.547
MOD_GSK3_1	528	535	PF00069	0.625
MOD_GSK3_1	557	564	PF00069	0.806
MOD_GSK3_1	76	83	PF00069	0.788
MOD_GSK3_1	87	94	PF00069	0.661
MOD_LATS_1	474	480	PF00433	0.515
MOD_N-GLC_1	468	473	PF02516	0.504
MOD_NEK2_1	125	130	PF00069	0.537
MOD_NEK2_1	246	251	PF00069	0.657
MOD_NEK2_1	339	344	PF00069	0.558
MOD_NEK2_1	425	430	PF00069	0.625
MOD_NEK2_1	464	469	PF00069	0.568
MOD_NEK2_1	489	494	PF00069	0.350
MOD_NEK2_1	91	96	PF00069	0.680
MOD_OFUCOSY	452	459	PF10250	0.531
MOD_PIKK_1	277	283	PF00454	0.723
MOD_PIKK_1	444	450	PF00454	0.508
MOD_PK_1	367	373	PF00069	0.663
MOD_PK_1	529	535	PF00069	0.549
MOD_PKA_1	275	281	PF00069	0.724
MOD_PKA_1	412	418	PF00069	0.549
MOD_PKA_2	101	107	PF00069	0.671
MOD_PKA_2	137	143	PF00069	0.521
MOD_PKA_2	170	176	PF00069	0.679
MOD_PKA_2	254	260	PF00069	0.649
MOD_PKA_2	274	280	PF00069	0.729
MOD_PKA_2	332	338	PF00069	0.575
MOD_PKA_2	406	412	PF00069	0.552
MOD_PKA_2	425	431	PF00069	0.516
MOD_PKA_2	528	534	PF00069	0.627
MOD_PKA_2	550	556	PF00069	0.526
MOD_PKB_1	436	444	PF00069	0.378
MOD_Plk_1	246	252	PF00069	0.657
MOD_Plk_1	460	466	PF00069	0.525
MOD_Plk_4	247	253	PF00069	0.620
MOD_Plk_4	325	331	PF00069	0.561
MOD_Plk_4	332	338	PF00069	0.516
MOD_Plk_4	489	495	PF00069	0.503
MOD_ProDKin_1	164	170	PF00069	0.682
MOD_ProDKin_1	201	207	PF00069	0.645
MOD_ProDKin_1	224	230	PF00069	0.695
MOD_ProDKin_1	231	237	PF00069	0.616
MOD_ProDKin_1	267	273	PF00069	0.689
MOD_ProDKin_1	288	294	PF00069	0.671
MOD_ProDKin_1	481	487	PF00069	0.560
MOD_ProDKin_1	507	513	PF00069	0.589
MOD_ProDKin_1	58	64	PF00069	0.717
MOD_ProDKin_1	83	89	PF00069	0.721
TRG_DiLeu_BaEn_4	397	403	PF01217	0.482
TRG_DiLeu_BaLyEn_6	400	405	PF01217	0.564
TRG_ENDOCYTIC_2	522	525	PF00928	0.531
TRG_ER_diArg_1	158	161	PF00400	0.522
TRG_ER_diArg_1	319	321	PF00400	0.600
TRG_ER_diArg_1	401	404	PF00400	0.538
TRG_ER_diArg_1	433	436	PF00400	0.520
TRG_NES_CRM1_1	491	506	PF08389	0.479
TRG_Pf-PMV_PEXEL_1	305	309	PF00026	0.572

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IC62	Leishmania donovani	85%	100%
A4H7Y8	Leishmania braziliensis	61%	100%
A4HWB6	Leishmania infantum	85%	100%
Q4QFG5	Leishmania major	83%	100%