Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AQ12_LEIMU

TriTrypDb:

LmxM.15.0150

Length:

182

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQ12

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQ12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	122	126	PF00656	0.619
CLV_C14_Caspase3-7	36	40	PF00656	0.498
CLV_NRD_NRD_1	65	67	PF00675	0.500
CLV_PCSK_KEX2_1	65	67	PF00082	0.508
CLV_PCSK_SKI1_1	65	69	PF00082	0.469
DEG_SPOP_SBC_1	130	134	PF00917	0.720
DOC_CYCLIN_yCln2_LP_2	156	162	PF00134	0.535
DOC_MAPK_DCC_7	155	165	PF00069	0.504
DOC_PP2B_LxvP_1	156	159	PF13499	0.482
DOC_PP4_FxxP_1	141	144	PF00568	0.567
DOC_PP4_FxxP_1	96	99	PF00568	0.478
DOC_USP7_MATH_1	130	134	PF00917	0.720
DOC_USP7_MATH_1	137	141	PF00917	0.578
DOC_USP7_MATH_1	161	165	PF00917	0.574
DOC_USP7_MATH_1	45	49	PF00917	0.628
LIG_Actin_WH2_2	60	76	PF00022	0.582
LIG_BIR_II_1	1	5	PF00653	0.538
LIG_FHA_1	112	118	PF00498	0.614
LIG_HP1_1	161	165	PF01393	0.444
LIG_LIR_Apic_2	139	144	PF02991	0.655
LIG_LIR_Gen_1	143	154	PF02991	0.587
LIG_LIR_Gen_1	15	24	PF02991	0.508
LIG_LIR_Gen_1	26	35	PF02991	0.387
LIG_LIR_Nem_3	143	149	PF02991	0.656
LIG_LIR_Nem_3	15	20	PF02991	0.510
LIG_LIR_Nem_3	26	30	PF02991	0.374
LIG_SH2_PTP2	146	149	PF00017	0.557
LIG_SH2_STAT5	146	149	PF00017	0.544
LIG_SH2_STAT5	84	87	PF00017	0.445
LIG_SH3_3	106	112	PF00018	0.470
LIG_SUMO_SIM_par_1	161	167	PF11976	0.522
LIG_TRFH_1	96	100	PF08558	0.482
LIG_WRC_WIRS_1	138	143	PF05994	0.576
LIG_WRC_WIRS_1	24	29	PF05994	0.538
MOD_CK1_1	164	170	PF00069	0.603
MOD_CK1_1	172	178	PF00069	0.535
MOD_CK1_1	49	55	PF00069	0.652
MOD_CK2_1	117	123	PF00069	0.683
MOD_CK2_1	137	143	PF00069	0.449
MOD_CK2_1	23	29	PF00069	0.639
MOD_CK2_1	38	44	PF00069	0.479
MOD_CK2_1	52	58	PF00069	0.583
MOD_GlcNHglycan	119	122	PF01048	0.783
MOD_GlcNHglycan	61	64	PF01048	0.556
MOD_GSK3_1	132	139	PF00069	0.577
MOD_GSK3_1	164	171	PF00069	0.588
MOD_GSK3_1	34	41	PF00069	0.560
MOD_GSK3_1	45	52	PF00069	0.764
MOD_N-GLC_1	49	54	PF02516	0.593
MOD_NEK2_1	1	6	PF00069	0.443
MOD_NEK2_1	117	122	PF00069	0.572
MOD_NEK2_1	145	150	PF00069	0.585
MOD_NEK2_1	168	173	PF00069	0.506
MOD_Plk_4	23	29	PF00069	0.486
TRG_DiLeu_BaLyEn_6	63	68	PF01217	0.456
TRG_DiLeu_BaLyEn_6	97	102	PF01217	0.491
TRG_ENDOCYTIC_2	146	149	PF00928	0.585
TRG_ER_diArg_1	64	66	PF00400	0.526

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HXC4	Leptomonas seymouri	38%	99%
A0A3Q8IDA8	Leishmania donovani	86%	100%
A4HWB2	Leishmania infantum	86%	100%
Q4QFG9	Leishmania major	83%	100%