zf-LSD1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

LSD1 zinc finger, putative

Species:

Leishmania mexicana

UniProt:

E9APQ7_LEIMU

TriTrypDb:

LmxM.14.0625

Length:

225

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	7
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043231	intracellular membrane-bounded organelle	4	7
GO:0110165	cellular anatomical entity	1	7

Expansion

Sequence features

E9APQ7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9APQ7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	82	86	PF00656	0.530
CLV_NRD_NRD_1	121	123	PF00675	0.821
CLV_NRD_NRD_1	132	134	PF00675	0.707
CLV_NRD_NRD_1	140	142	PF00675	0.499
CLV_NRD_NRD_1	144	146	PF00675	0.678
CLV_NRD_NRD_1	180	182	PF00675	0.699
CLV_NRD_NRD_1	204	206	PF00675	0.658
CLV_PCSK_KEX2_1	121	123	PF00082	0.821
CLV_PCSK_KEX2_1	132	134	PF00082	0.707
CLV_PCSK_KEX2_1	139	141	PF00082	0.535
CLV_PCSK_KEX2_1	144	146	PF00082	0.670
CLV_PCSK_KEX2_1	180	182	PF00082	0.704
CLV_PCSK_KEX2_1	204	206	PF00082	0.668
CLV_PCSK_PC7_1	140	146	PF00082	0.615
CLV_PCSK_SKI1_1	13	17	PF00082	0.513
CLV_PCSK_SKI1_1	46	50	PF00082	0.304
DEG_Nend_Nbox_1	1	3	PF02207	0.640
DOC_CYCLIN_yCln2_LP_2	15	21	PF00134	0.411
DOC_CYCLIN_yCln2_LP_2	73	76	PF00134	0.512
DOC_MAPK_MEF2A_6	213	220	PF00069	0.755
DOC_PP2B_LxvP_1	49	52	PF13499	0.467
DOC_PP2B_LxvP_1	73	76	PF13499	0.512
DOC_USP7_MATH_1	193	197	PF00917	0.768
DOC_USP7_MATH_1	76	80	PF00917	0.549
LIG_14-3-3_CanoR_1	13	18	PF00244	0.411
LIG_14-3-3_CanoR_1	132	142	PF00244	0.763
LIG_BRCT_BRCA1_1	123	127	PF00533	0.696
LIG_EVH1_1	74	78	PF00568	0.598
LIG_FHA_1	14	20	PF00498	0.513
LIG_FHA_1	180	186	PF00498	0.601
LIG_FHA_1	215	221	PF00498	0.624
LIG_FHA_1	53	59	PF00498	0.521
LIG_FHA_1	87	93	PF00498	0.657
LIG_FHA_2	63	69	PF00498	0.427
LIG_MYND_1	98	102	PF01753	0.767
LIG_SH2_STAT3	9	12	PF00017	0.411
LIG_SH2_STAT5	194	197	PF00017	0.743
LIG_SH2_STAT5	94	97	PF00017	0.648
LIG_SH3_2	98	103	PF14604	0.692
LIG_SH3_3	184	190	PF00018	0.732
LIG_SH3_3	196	202	PF00018	0.646
LIG_SH3_3	72	78	PF00018	0.588
LIG_SH3_3	92	98	PF00018	0.642
LIG_SUMO_SIM_anti_2	55	60	PF11976	0.567
LIG_SUMO_SIM_par_1	216	222	PF11976	0.632
LIG_WW_2	75	78	PF00397	0.616
LIG_WW_3	100	104	PF00397	0.763
MOD_CK1_1	197	203	PF00069	0.690
MOD_CK1_1	96	102	PF00069	0.666
MOD_CK2_1	140	146	PF00069	0.832
MOD_Cter_Amidation	178	181	PF01082	0.656
MOD_GlcNHglycan	133	136	PF01048	0.787
MOD_GlcNHglycan	196	199	PF01048	0.773
MOD_GSK3_1	113	120	PF00069	0.816
MOD_GSK3_1	193	200	PF00069	0.753
MOD_NEK2_1	117	122	PF00069	0.801
MOD_NEK2_1	219	224	PF00069	0.641
MOD_NEK2_2	20	25	PF00069	0.411
MOD_PIKK_1	149	155	PF00454	0.547
MOD_PKA_1	121	127	PF00069	0.824
MOD_PKA_1	140	146	PF00069	0.501
MOD_PKA_2	121	127	PF00069	0.783
MOD_PKA_2	131	137	PF00069	0.661
MOD_PKA_2	140	146	PF00069	0.501
MOD_PKA_2	179	185	PF00069	0.715
MOD_Plk_4	214	220	PF00069	0.647
TRG_ER_diArg_1	102	105	PF00400	0.705
TRG_ER_diArg_1	121	123	PF00400	0.511
TRG_ER_diArg_1	139	141	PF00400	0.622
TRG_ER_diArg_1	25	28	PF00400	0.420

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4B1	Leptomonas seymouri	47%	100%
A0A3Q8IBZ4	Leishmania donovani	83%	100%
A4H7M0	Leishmania braziliensis	66%	99%
A4HW05	Leishmania infantum	83%	100%
Q4QFS2	Leishmania major	81%	100%