Transposase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Transposase

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9APQ2_LEIMU

TriTrypDb:

LmxM.14.0580

Length:

126

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9APQ2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9APQ2

PDB structure(s): 7am2_CD

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	39	41	PF00675	0.471
CLV_NRD_NRD_1	69	71	PF00675	0.395
CLV_NRD_NRD_1	88	90	PF00675	0.403
CLV_PCSK_KEX2_1	38	40	PF00082	0.449
CLV_PCSK_KEX2_1	69	71	PF00082	0.395
CLV_PCSK_KEX2_1	88	90	PF00082	0.493
CLV_PCSK_PC7_1	35	41	PF00082	0.414
CLV_PCSK_SKI1_1	69	73	PF00082	0.353
DEG_Nend_Nbox_1	1	3	PF02207	0.443
DOC_CYCLIN_RxL_1	66	74	PF00134	0.475
DOC_MAPK_gen_1	35	43	PF00069	0.495
DOC_MAPK_gen_1	88	97	PF00069	0.425
DOC_PP1_RVXF_1	105	112	PF00149	0.435
DOC_USP7_UBL2_3	73	77	PF12436	0.421
DOC_WW_Pin1_4	12	17	PF00397	0.484
DOC_WW_Pin1_4	3	8	PF00397	0.686
LIG_14-3-3_CanoR_1	100	109	PF00244	0.394
LIG_FHA_1	13	19	PF00498	0.618
LIG_FHA_1	3	9	PF00498	0.682
LIG_FHA_1	76	82	PF00498	0.495
LIG_FHA_2	80	86	PF00498	0.500
LIG_LIR_Apic_2	50	56	PF02991	0.399
LIG_LIR_LC3C_4	78	81	PF02991	0.487
LIG_LIR_Nem_3	74	79	PF02991	0.440
LIG_SH2_CRK	68	72	PF00017	0.360
LIG_SH2_CRK	76	80	PF00017	0.494
LIG_SH2_NCK_1	33	37	PF00017	0.547
LIG_SH2_SRC	53	56	PF00017	0.422
LIG_SH2_STAP1	93	97	PF00017	0.405
LIG_SH2_STAT5	33	36	PF00017	0.551
LIG_SH2_STAT5	53	56	PF00017	0.420
LIG_SH3_1	53	59	PF00018	0.375
LIG_SH3_3	53	59	PF00018	0.417
LIG_SUMO_SIM_par_1	77	83	PF11976	0.491
LIG_WW_1	30	33	PF00397	0.571
MOD_CDC14_SPxK_1	6	9	PF00782	0.500
MOD_CDK_SPxK_1	3	9	PF00069	0.504
MOD_CK1_1	99	105	PF00069	0.533
MOD_GSK3_1	75	82	PF00069	0.427
MOD_GSK3_1	95	102	PF00069	0.399
MOD_NEK2_1	2	7	PF00069	0.476
MOD_NEK2_1	95	100	PF00069	0.368
MOD_PIKK_1	48	54	PF00454	0.546
MOD_PKA_2	99	105	PF00069	0.401
MOD_Plk_1	48	54	PF00069	0.427
MOD_Plk_4	75	81	PF00069	0.410
MOD_ProDKin_1	12	18	PF00069	0.483
MOD_ProDKin_1	3	9	PF00069	0.687
TRG_DiLeu_BaLyEn_6	67	72	PF01217	0.414
TRG_ENDOCYTIC_2	68	71	PF00928	0.350
TRG_ENDOCYTIC_2	76	79	PF00928	0.497
TRG_ER_diArg_1	38	40	PF00400	0.449
TRG_ER_diArg_1	68	70	PF00400	0.408
TRG_ER_diArg_1	87	89	PF00400	0.478
TRG_NLS_MonoExtC_3	88	94	PF00514	0.377
TRG_NLS_MonoExtN_4	88	93	PF00514	0.491
TRG_Pf-PMV_PEXEL_1	69	74	PF00026	0.443

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCX7	Leptomonas seymouri	81%	100%
A0A0S4J267	Bodo saltans	57%	100%
A0A1X0NNN4	Trypanosomatidae	67%	100%
A0A3R7MRR7	Trypanosoma rangeli	65%	100%
A0A3S7WSX5	Leishmania donovani	95%	100%
A4H7L5	Leishmania braziliensis	92%	100%
A4HW00	Leishmania infantum	94%	100%
C9ZT21	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	63%	100%
Q4QFS7	Leishmania major	94%	100%