LeishMANIAdb
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Sec5 domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Sec5 domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9APL6_LEIMU
TriTrypDb:
LmxM.14.0230
Length:
1832

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
TermNameLevelCount
GO:0000145 exocyst 3 9
GO:0032991 protein-containing complex 1 9
GO:0099023 vesicle tethering complex 2 9
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Expansion

Sequence features

E9APL6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
TermNameLevelCount
GO:0006810 transport 3 9
GO:0006887 exocytosis 4 9
GO:0006892 post-Golgi vesicle-mediated transport 6 9
GO:0006893 Golgi to plasma membrane transport 5 9
GO:0009987 cellular process 1 9
GO:0016192 vesicle-mediated transport 4 9
GO:0032940 secretion by cell 3 9
GO:0046903 secretion 4 9
GO:0048193 Golgi vesicle transport 5 9
GO:0051179 localization 1 9
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Could not find GO molecular_function term for this entry.

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1210 1214 PF00656 0.456
CLV_C14_Caspase3-7 1548 1552 PF00656 0.574
CLV_C14_Caspase3-7 1590 1594 PF00656 0.542
CLV_C14_Caspase3-7 164 168 PF00656 0.533
CLV_C14_Caspase3-7 1656 1660 PF00656 0.547
CLV_C14_Caspase3-7 1687 1691 PF00656 0.710
CLV_C14_Caspase3-7 1741 1745 PF00656 0.635
CLV_C14_Caspase3-7 191 195 PF00656 0.518
CLV_C14_Caspase3-7 224 228 PF00656 0.676
CLV_C14_Caspase3-7 314 318 PF00656 0.479
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P5B3 Leptomonas seymouri 55% 100%
A0A1X0NNR0 Trypanosomatidae 33% 100%
A0A3Q8I9S1 Leishmania donovani 90% 99%
A4H7I3 Leishmania braziliensis 75% 98%
A4HVW5 Leishmania infantum 89% 100%
Q4QFW2 Leishmania major 89% 100%
V5BD59 Trypanosoma cruzi 34% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS