LeishMANIAdb
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DNA-directed DNA polymerase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
DNA-directed DNA polymerase
Gene product:
mitochondrial DNA polymerase I protein D, putative
Species:
Leishmania mexicana
UniProt:
E9API7_LEIMU
TriTrypDb:
LmxM.13.1630
Length:
1579

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9API7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006259 DNA metabolic process 4 12
GO:0006260 DNA replication 5 12
GO:0006261 DNA-templated DNA replication 6 12
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009987 cellular process 1 12
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0044260 obsolete cellular macromolecule metabolic process 3 12
GO:0046483 heterocycle metabolic process 3 12
GO:0071704 organic substance metabolic process 2 12
GO:0090304 nucleic acid metabolic process 4 12
GO:1901360 organic cyclic compound metabolic process 3 12
GO:0006281 DNA repair 5 1
GO:0006302 double-strand break repair 6 1
GO:0006950 response to stress 2 1
GO:0006974 DNA damage response 4 1
GO:0033554 cellular response to stress 3 1
GO:0050896 response to stimulus 1 1
GO:0051716 cellular response to stimulus 2 1
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 12
GO:0003677 DNA binding 4 12
GO:0003824 catalytic activity 1 12
GO:0003887 DNA-directed DNA polymerase activity 5 12
GO:0005488 binding 1 12
GO:0016740 transferase activity 2 12
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 12
GO:0016779 nucleotidyltransferase activity 4 12
GO:0034061 DNA polymerase activity 4 12
GO:0097159 organic cyclic compound binding 2 12
GO:0140097 catalytic activity, acting on DNA 3 12
GO:0140640 catalytic activity, acting on a nucleic acid 2 12
GO:1901363 heterocyclic compound binding 2 12
GO:0004518 nuclease activity 4 1
GO:0004527 exonuclease activity 5 1
GO:0008408 3'-5' exonuclease activity 6 1
GO:0016787 hydrolase activity 2 1
GO:0016788 hydrolase activity, acting on ester bonds 3 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1121 1125 PF00656 0.529
CLV_C14_Caspase3-7 1227 1231 PF00656 0.537
CLV_C14_Caspase3-7 535 539 PF00656 0.526
CLV_C14_Caspase3-7 926 930 PF00656 0.529
CLV_MEL_PAP_1 189 195 PF00089 0.457
CLV_MEL_PAP_1 223 229 PF00089 0.379
CLV_NRD_NRD_1 1009 1011 PF00675 0.609
CLV_NRD_NRD_1 1091 1093 PF00675 0.592
CLV_NRD_NRD_1 1112 1114 PF00675 0.422
CLV_NRD_NRD_1 1126 1128 PF00675 0.306
CLV_NRD_NRD_1 1180 1182 PF00675 0.290
CLV_NRD_NRD_1 1462 1464 PF00675 0.362
CLV_NRD_NRD_1 191 193 PF00675 0.452
CLV_NRD_NRD_1 198 200 PF00675 0.466
CLV_NRD_NRD_1 210 212 PF00675 0.218
CLV_NRD_NRD_1 247 249 PF00675 0.481
CLV_NRD_NRD_1 351 353 PF00675 0.508
CLV_NRD_NRD_1 444 446 PF00675 0.551
CLV_NRD_NRD_1 465 467 PF00675 0.484
CLV_NRD_NRD_1 478 480 PF00675 0.279
CLV_NRD_NRD_1 509 511 PF00675 0.505
CLV_NRD_NRD_1 569 571 PF00675 0.362
CLV_NRD_NRD_1 574 576 PF00675 0.365
CLV_NRD_NRD_1 708 710 PF00675 0.509
CLV_NRD_NRD_1 723 725 PF00675 0.358
CLV_NRD_NRD_1 824 826 PF00675 0.399
CLV_NRD_NRD_1 835 837 PF00675 0.446
CLV_NRD_NRD_1 861 863 PF00675 0.380
CLV_PCSK_FUR_1 1110 1114 PF00082 0.507
CLV_PCSK_FUR_1 479 483 PF00082 0.428
CLV_PCSK_KEX2_1 1008 1010 PF00082 0.651
CLV_PCSK_KEX2_1 103 105 PF00082 0.394
CLV_PCSK_KEX2_1 1038 1040 PF00082 0.566
CLV_PCSK_KEX2_1 1112 1114 PF00082 0.409
CLV_PCSK_KEX2_1 1128 1130 PF00082 0.333
CLV_PCSK_KEX2_1 1180 1182 PF00082 0.362
CLV_PCSK_KEX2_1 1327 1329 PF00082 0.276
CLV_PCSK_KEX2_1 191 193 PF00082 0.469
CLV_PCSK_KEX2_1 210 212 PF00082 0.219
CLV_PCSK_KEX2_1 247 249 PF00082 0.412
CLV_PCSK_KEX2_1 403 405 PF00082 0.553
CLV_PCSK_KEX2_1 444 446 PF00082 0.551
CLV_PCSK_KEX2_1 465 467 PF00082 0.429
CLV_PCSK_KEX2_1 478 480 PF00082 0.289
CLV_PCSK_KEX2_1 481 483 PF00082 0.433
CLV_PCSK_KEX2_1 509 511 PF00082 0.505
CLV_PCSK_KEX2_1 574 576 PF00082 0.361
CLV_PCSK_KEX2_1 620 622 PF00082 0.545
CLV_PCSK_KEX2_1 708 710 PF00082 0.601
CLV_PCSK_KEX2_1 835 837 PF00082 0.518
CLV_PCSK_KEX2_1 861 863 PF00082 0.312
CLV_PCSK_PC1ET2_1 103 105 PF00082 0.461
CLV_PCSK_PC1ET2_1 1038 1040 PF00082 0.554
CLV_PCSK_PC1ET2_1 1128 1130 PF00082 0.454
CLV_PCSK_PC1ET2_1 1327 1329 PF00082 0.276
CLV_PCSK_PC1ET2_1 403 405 PF00082 0.588
CLV_PCSK_PC1ET2_1 481 483 PF00082 0.435
CLV_PCSK_PC1ET2_1 620 622 PF00082 0.545
CLV_PCSK_PC7_1 570 576 PF00082 0.384
CLV_PCSK_SKI1_1 100 104 PF00082 0.430
CLV_PCSK_SKI1_1 1049 1053 PF00082 0.450
CLV_PCSK_SKI1_1 1112 1116 PF00082 0.426
CLV_PCSK_SKI1_1 1129 1133 PF00082 0.424
CLV_PCSK_SKI1_1 1279 1283 PF00082 0.276
CLV_PCSK_SKI1_1 1327 1331 PF00082 0.332
CLV_PCSK_SKI1_1 1406 1410 PF00082 0.353
CLV_PCSK_SKI1_1 1433 1437 PF00082 0.276
CLV_PCSK_SKI1_1 1443 1447 PF00082 0.276
CLV_PCSK_SKI1_1 1495 1499 PF00082 0.275
CLV_PCSK_SKI1_1 1541 1545 PF00082 0.270
CLV_PCSK_SKI1_1 21 25 PF00082 0.394
CLV_PCSK_SKI1_1 211 215 PF00082 0.289
CLV_PCSK_SKI1_1 364 368 PF00082 0.496
CLV_PCSK_SKI1_1 458 462 PF00082 0.438
CLV_PCSK_SKI1_1 570 574 PF00082 0.349
CLV_PCSK_SKI1_1 724 728 PF00082 0.515
CLV_PCSK_SKI1_1 754 758 PF00082 0.543
CLV_PCSK_SKI1_1 836 840 PF00082 0.583
CLV_PCSK_SKI1_1 862 866 PF00082 0.362
DEG_APCC_DBOX_1 1126 1134 PF00400 0.394
DEG_APCC_DBOX_1 1540 1548 PF00400 0.459
DEG_APCC_DBOX_1 198 206 PF00400 0.588
DEG_APCC_KENBOX_2 1392 1396 PF00400 0.562
DEG_APCC_KENBOX_2 488 492 PF00400 0.400
DEG_COP1_1 1447 1455 PF00400 0.487
DEG_COP1_1 277 287 PF00400 0.468
DEG_Nend_UBRbox_1 1 4 PF02207 0.423
DEG_ODPH_VHL_1 107 119 PF01847 0.381
DEG_SCF_FBW7_1 870 875 PF00400 0.430
DOC_ANK_TNKS_1 620 627 PF00023 0.532
DOC_CKS1_1 193 198 PF01111 0.579
DOC_CYCLIN_RxL_1 100 111 PF00134 0.510
DOC_CYCLIN_RxL_1 1047 1056 PF00134 0.519
DOC_CYCLIN_RxL_1 463 474 PF00134 0.342
DOC_CYCLIN_yCln2_LP_2 784 790 PF00134 0.446
DOC_MAPK_gen_1 1035 1044 PF00069 0.572
DOC_MAPK_gen_1 1127 1135 PF00069 0.455
DOC_MAPK_gen_1 1346 1356 PF00069 0.474
DOC_MAPK_gen_1 210 220 PF00069 0.346
DOC_MAPK_gen_1 288 297 PF00069 0.420
DOC_MAPK_gen_1 465 472 PF00069 0.430
DOC_MAPK_gen_1 534 542 PF00069 0.545
DOC_MAPK_gen_1 975 982 PF00069 0.451
DOC_MAPK_HePTP_8 208 220 PF00069 0.369
DOC_MAPK_MEF2A_6 1100 1109 PF00069 0.488
DOC_MAPK_MEF2A_6 127 135 PF00069 0.529
DOC_MAPK_MEF2A_6 211 220 PF00069 0.360
DOC_MAPK_MEF2A_6 465 472 PF00069 0.430
DOC_MAPK_NFAT4_5 465 473 PF00069 0.376
DOC_PIKK_1 1311 1318 PF02985 0.478
DOC_PP1_RVXF_1 563 570 PF00149 0.461
DOC_PP2B_LxvP_1 282 285 PF13499 0.448
DOC_PP2B_LxvP_1 540 543 PF13499 0.398
DOC_PP2B_LxvP_1 784 787 PF13499 0.459
DOC_PP4_FxxP_1 1147 1150 PF00568 0.508
DOC_PP4_FxxP_1 193 196 PF00568 0.570
DOC_PP4_FxxP_1 541 544 PF00568 0.379
DOC_PP4_FxxP_1 767 770 PF00568 0.468
DOC_PP4_FxxP_1 783 786 PF00568 0.426
DOC_SPAK_OSR1_1 905 909 PF12202 0.378
DOC_USP7_MATH_1 1020 1024 PF00917 0.634
DOC_USP7_MATH_1 1563 1567 PF00917 0.562
DOC_USP7_MATH_1 175 179 PF00917 0.485
DOC_USP7_MATH_1 310 314 PF00917 0.406
DOC_USP7_MATH_1 384 388 PF00917 0.463
DOC_USP7_MATH_1 750 754 PF00917 0.482
DOC_USP7_MATH_2 1271 1277 PF00917 0.537
DOC_USP7_UBL2_3 1031 1035 PF12436 0.625
DOC_USP7_UBL2_3 1158 1162 PF12436 0.535
DOC_USP7_UBL2_3 353 357 PF12436 0.567
DOC_USP7_UBL2_3 880 884 PF12436 0.452
DOC_WW_Pin1_4 1466 1471 PF00397 0.476
DOC_WW_Pin1_4 192 197 PF00397 0.569
DOC_WW_Pin1_4 302 307 PF00397 0.490
DOC_WW_Pin1_4 379 384 PF00397 0.422
DOC_WW_Pin1_4 868 873 PF00397 0.382
LIG_14-3-3_CanoR_1 1180 1190 PF00244 0.556
LIG_14-3-3_CanoR_1 1328 1332 PF00244 0.537
LIG_14-3-3_CanoR_1 1374 1382 PF00244 0.581
LIG_14-3-3_CanoR_1 1443 1452 PF00244 0.476
LIG_14-3-3_CanoR_1 1463 1470 PF00244 0.345
LIG_14-3-3_CanoR_1 199 203 PF00244 0.419
LIG_14-3-3_CanoR_1 247 253 PF00244 0.445
LIG_14-3-3_CanoR_1 288 297 PF00244 0.413
LIG_14-3-3_CanoR_1 335 339 PF00244 0.493
LIG_14-3-3_CanoR_1 364 373 PF00244 0.496
LIG_14-3-3_CanoR_1 763 767 PF00244 0.410
LIG_14-3-3_CanoR_1 825 834 PF00244 0.444
LIG_14-3-3_CanoR_1 977 983 PF00244 0.344
LIG_Actin_WH2_2 560 576 PF00022 0.416
LIG_APCC_ABBAyCdc20_2 444 450 PF00400 0.543
LIG_BRCT_BRCA1_1 1464 1468 PF00533 0.476
LIG_BRCT_BRCA1_1 304 308 PF00533 0.395
LIG_CaM_IQ_9 1380 1395 PF13499 0.487
LIG_CaM_IQ_9 437 453 PF13499 0.563
LIG_deltaCOP1_diTrp_1 110 119 PF00928 0.403
LIG_deltaCOP1_diTrp_1 58 67 PF00928 0.346
LIG_EH_1 484 488 PF12763 0.403
LIG_EH_1 8 12 PF12763 0.521
LIG_eIF4E_1 76 82 PF01652 0.452
LIG_FHA_1 109 115 PF00498 0.358
LIG_FHA_1 1138 1144 PF00498 0.490
LIG_FHA_1 1185 1191 PF00498 0.476
LIG_FHA_1 1206 1212 PF00498 0.551
LIG_FHA_1 1231 1237 PF00498 0.476
LIG_FHA_1 1255 1261 PF00498 0.476
LIG_FHA_1 1337 1343 PF00498 0.501
LIG_FHA_1 1508 1514 PF00498 0.501
LIG_FHA_1 235 241 PF00498 0.416
LIG_FHA_1 260 266 PF00498 0.460
LIG_FHA_1 267 273 PF00498 0.461
LIG_FHA_1 335 341 PF00498 0.582
LIG_FHA_1 472 478 PF00498 0.388
LIG_FHA_1 48 54 PF00498 0.377
LIG_FHA_1 611 617 PF00498 0.451
LIG_FHA_1 627 633 PF00498 0.330
LIG_FHA_1 636 642 PF00498 0.390
LIG_FHA_1 646 652 PF00498 0.393
LIG_FHA_1 755 761 PF00498 0.505
LIG_FHA_1 763 769 PF00498 0.395
LIG_FHA_1 850 856 PF00498 0.550
LIG_FHA_1 873 879 PF00498 0.430
LIG_FHA_1 913 919 PF00498 0.440
LIG_FHA_1 957 963 PF00498 0.387
LIG_FHA_1 983 989 PF00498 0.389
LIG_FHA_2 1099 1105 PF00498 0.584
LIG_FHA_2 1222 1228 PF00498 0.521
LIG_FHA_2 1445 1451 PF00498 0.476
LIG_FHA_2 148 154 PF00498 0.505
LIG_FHA_2 1510 1516 PF00498 0.476
LIG_FHA_2 229 235 PF00498 0.390
LIG_FHA_2 239 245 PF00498 0.427
LIG_FHA_2 47 53 PF00498 0.398
LIG_FHA_2 588 594 PF00498 0.423
LIG_FHA_2 634 640 PF00498 0.366
LIG_FHA_2 677 683 PF00498 0.411
LIG_FHA_2 686 692 PF00498 0.473
LIG_FHA_2 891 897 PF00498 0.575
LIG_FHA_2 919 925 PF00498 0.469
LIG_LIR_Apic_2 1145 1150 PF02991 0.509
LIG_LIR_Apic_2 538 544 PF02991 0.406
LIG_LIR_Apic_2 628 633 PF02991 0.423
LIG_LIR_Apic_2 765 770 PF02991 0.427
LIG_LIR_Gen_1 1069 1079 PF02991 0.335
LIG_LIR_Gen_1 1141 1152 PF02991 0.374
LIG_LIR_Gen_1 115 121 PF02991 0.443
LIG_LIR_Gen_1 1294 1305 PF02991 0.476
LIG_LIR_Gen_1 1335 1345 PF02991 0.476
LIG_LIR_Gen_1 1350 1360 PF02991 0.476
LIG_LIR_Gen_1 1402 1412 PF02991 0.476
LIG_LIR_Gen_1 233 243 PF02991 0.391
LIG_LIR_Gen_1 337 346 PF02991 0.487
LIG_LIR_Gen_1 490 498 PF02991 0.404
LIG_LIR_Gen_1 546 556 PF02991 0.373
LIG_LIR_Gen_1 631 641 PF02991 0.445
LIG_LIR_Gen_1 943 952 PF02991 0.399
LIG_LIR_Nem_3 1061 1066 PF02991 0.355
LIG_LIR_Nem_3 1069 1074 PF02991 0.320
LIG_LIR_Nem_3 1141 1147 PF02991 0.373
LIG_LIR_Nem_3 115 119 PF02991 0.390
LIG_LIR_Nem_3 1294 1300 PF02991 0.476
LIG_LIR_Nem_3 1335 1341 PF02991 0.476
LIG_LIR_Nem_3 1350 1356 PF02991 0.476
LIG_LIR_Nem_3 1396 1401 PF02991 0.487
LIG_LIR_Nem_3 1524 1529 PF02991 0.488
LIG_LIR_Nem_3 233 239 PF02991 0.382
LIG_LIR_Nem_3 337 341 PF02991 0.495
LIG_LIR_Nem_3 490 495 PF02991 0.408
LIG_LIR_Nem_3 546 551 PF02991 0.380
LIG_LIR_Nem_3 566 572 PF02991 0.160
LIG_LIR_Nem_3 581 587 PF02991 0.259
LIG_LIR_Nem_3 631 637 PF02991 0.429
LIG_LIR_Nem_3 680 686 PF02991 0.425
LIG_LIR_Nem_3 808 814 PF02991 0.430
LIG_LIR_Nem_3 947 951 PF02991 0.347
LIG_LRP6_Inhibitor_1 336 342 PF00058 0.623
LIG_LYPXL_S_1 1547 1551 PF13949 0.287
LIG_LYPXL_yS_3 1548 1551 PF13949 0.487
LIG_MLH1_MIPbox_1 304 308 PF16413 0.496
LIG_NRBOX 267 273 PF00104 0.434
LIG_PDZ_Class_1 1574 1579 PF00595 0.531
LIG_Pex14_1 1063 1067 PF04695 0.341
LIG_Pex14_1 112 116 PF04695 0.344
LIG_Pex14_1 580 584 PF04695 0.363
LIG_Pex14_2 1282 1286 PF04695 0.537
LIG_Pex14_2 1432 1436 PF04695 0.487
LIG_PTB_Apo_2 1497 1504 PF02174 0.537
LIG_PTB_Apo_2 1542 1549 PF02174 0.487
LIG_PTB_Apo_2 368 375 PF02174 0.410
LIG_PTB_Apo_2 777 784 PF02174 0.571
LIG_PTB_Phospho_1 1497 1503 PF10480 0.537
LIG_PTB_Phospho_1 1542 1548 PF10480 0.487
LIG_REV1ctd_RIR_1 1429 1436 PF16727 0.501
LIG_REV1ctd_RIR_1 737 747 PF16727 0.345
LIG_SH2_CRK 1119 1123 PF00017 0.438
LIG_SH2_CRK 1503 1507 PF00017 0.487
LIG_SH2_CRK 1526 1530 PF00017 0.562
LIG_SH2_CRK 236 240 PF00017 0.469
LIG_SH2_CRK 480 484 PF00017 0.422
LIG_SH2_CRK 548 552 PF00017 0.355
LIG_SH2_CRK 634 638 PF00017 0.425
LIG_SH2_CRK 683 687 PF00017 0.455
LIG_SH2_GRB2like 1118 1121 PF00017 0.447
LIG_SH2_NCK_1 36 40 PF00017 0.481
LIG_SH2_NCK_1 520 524 PF00017 0.566
LIG_SH2_NCK_1 630 634 PF00017 0.442
LIG_SH2_PTP2 1067 1070 PF00017 0.355
LIG_SH2_PTP2 492 495 PF00017 0.442
LIG_SH2_SRC 1067 1070 PF00017 0.355
LIG_SH2_SRC 36 39 PF00017 0.480
LIG_SH2_SRC 520 523 PF00017 0.564
LIG_SH2_SRC 630 633 PF00017 0.414
LIG_SH2_SRC 640 643 PF00017 0.371
LIG_SH2_SRC 814 817 PF00017 0.540
LIG_SH2_SRC 961 964 PF00017 0.504
LIG_SH2_SRC 968 971 PF00017 0.515
LIG_SH2_STAP1 1144 1148 PF00017 0.397
LIG_SH2_STAP1 1338 1342 PF00017 0.487
LIG_SH2_STAP1 1415 1419 PF00017 0.537
LIG_SH2_STAP1 236 240 PF00017 0.469
LIG_SH2_STAP1 548 552 PF00017 0.371
LIG_SH2_STAP1 996 1000 PF00017 0.497
LIG_SH2_STAT3 1476 1479 PF00017 0.476
LIG_SH2_STAT3 448 451 PF00017 0.592
LIG_SH2_STAT3 609 612 PF00017 0.432
LIG_SH2_STAT3 818 821 PF00017 0.387
LIG_SH2_STAT3 992 995 PF00017 0.376
LIG_SH2_STAT5 1067 1070 PF00017 0.355
LIG_SH2_STAT5 1168 1171 PF00017 0.476
LIG_SH2_STAT5 1199 1202 PF00017 0.476
LIG_SH2_STAT5 1338 1341 PF00017 0.501
LIG_SH2_STAT5 1444 1447 PF00017 0.476
LIG_SH2_STAT5 236 239 PF00017 0.466
LIG_SH2_STAT5 29 32 PF00017 0.379
LIG_SH2_STAT5 318 321 PF00017 0.528
LIG_SH2_STAT5 361 364 PF00017 0.559
LIG_SH2_STAT5 467 470 PF00017 0.374
LIG_SH2_STAT5 492 495 PF00017 0.435
LIG_SH2_STAT5 511 514 PF00017 0.250
LIG_SH2_STAT5 587 590 PF00017 0.366
LIG_SH2_STAT5 640 643 PF00017 0.385
LIG_SH2_STAT5 76 79 PF00017 0.419
LIG_SH2_STAT5 814 817 PF00017 0.419
LIG_SH2_STAT5 951 954 PF00017 0.400
LIG_SH2_STAT5 961 964 PF00017 0.404
LIG_SH2_STAT5 968 971 PF00017 0.416
LIG_SH3_2 1026 1031 PF14604 0.626
LIG_SH3_3 1023 1029 PF00018 0.641
LIG_SH3_3 103 109 PF00018 0.353
LIG_SH3_3 126 132 PF00018 0.483
LIG_SH3_3 149 155 PF00018 0.311
LIG_SH3_3 1552 1558 PF00018 0.487
LIG_SH3_3 300 306 PF00018 0.376
LIG_SH3_3 480 486 PF00018 0.409
LIG_SH3_3 502 508 PF00018 0.441
LIG_SH3_3 880 886 PF00018 0.525
LIG_SUMO_SIM_anti_2 1298 1304 PF11976 0.476
LIG_SUMO_SIM_anti_2 1532 1538 PF11976 0.581
LIG_SUMO_SIM_anti_2 52 59 PF11976 0.496
LIG_SUMO_SIM_anti_2 984 990 PF11976 0.412
LIG_SUMO_SIM_par_1 1406 1411 PF11976 0.476
LIG_SUMO_SIM_par_1 237 245 PF11976 0.486
LIG_SUMO_SIM_par_1 468 476 PF11976 0.355
LIG_TRAF2_1 121 124 PF00917 0.377
LIG_TRAF2_1 329 332 PF00917 0.643
LIG_TRAF2_1 393 396 PF00917 0.470
LIG_TRAF2_1 590 593 PF00917 0.245
LIG_TYR_ITIM 1336 1341 PF00017 0.476
LIG_TYR_ITIM 632 637 PF00017 0.415
LIG_UBA3_1 1132 1138 PF00899 0.530
LIG_UBA3_1 1212 1220 PF00899 0.475
LIG_UBA3_1 798 806 PF00899 0.526
LIG_WRC_WIRS_1 1362 1367 PF05994 0.476
LIG_WRC_WIRS_1 735 740 PF05994 0.418
LIG_WW_1 154 157 PF00397 0.403
MOD_CDK_SPxxK_3 192 199 PF00069 0.577
MOD_CK1_1 1012 1018 PF00069 0.606
MOD_CK1_1 1184 1190 PF00069 0.476
MOD_CK1_1 1207 1213 PF00069 0.525
MOD_CK1_1 1241 1247 PF00069 0.501
MOD_CK1_1 1377 1383 PF00069 0.476
MOD_CK1_1 1411 1417 PF00069 0.542
MOD_CK1_1 198 204 PF00069 0.444
MOD_CK1_1 278 284 PF00069 0.447
MOD_CK1_1 47 53 PF00069 0.468
MOD_CK1_1 524 530 PF00069 0.525
MOD_CK1_1 536 542 PF00069 0.356
MOD_CK1_1 635 641 PF00069 0.497
MOD_CK1_1 888 894 PF00069 0.603
MOD_CK1_1 92 98 PF00069 0.453
MOD_CK2_1 1221 1227 PF00069 0.521
MOD_CK2_1 1295 1301 PF00069 0.476
MOD_CK2_1 228 234 PF00069 0.372
MOD_CK2_1 254 260 PF00069 0.461
MOD_CK2_1 326 332 PF00069 0.644
MOD_CK2_1 46 52 PF00069 0.371
MOD_CK2_1 587 593 PF00069 0.400
MOD_CK2_1 633 639 PF00069 0.384
MOD_CK2_1 676 682 PF00069 0.406
MOD_CK2_1 826 832 PF00069 0.573
MOD_CK2_1 870 876 PF00069 0.431
MOD_CK2_1 890 896 PF00069 0.610
MOD_Cter_Amidation 1036 1039 PF01082 0.605
MOD_Cter_Amidation 1093 1096 PF01082 0.742
MOD_DYRK1A_RPxSP_1 302 306 PF00069 0.491
MOD_GlcNHglycan 1015 1018 PF01048 0.650
MOD_GlcNHglycan 1261 1264 PF01048 0.287
MOD_GlcNHglycan 1410 1413 PF01048 0.276
MOD_GlcNHglycan 177 180 PF01048 0.470
MOD_GlcNHglycan 386 389 PF01048 0.490
MOD_GlcNHglycan 46 49 PF01048 0.479
MOD_GlcNHglycan 495 498 PF01048 0.398
MOD_GlcNHglycan 851 855 PF01048 0.577
MOD_GlcNHglycan 872 875 PF01048 0.424
MOD_GlcNHglycan 887 890 PF01048 0.543
MOD_GlcNHglycan 91 94 PF01048 0.526
MOD_GSK3_1 1000 1007 PF00069 0.525
MOD_GSK3_1 1009 1016 PF00069 0.580
MOD_GSK3_1 108 115 PF00069 0.399
MOD_GSK3_1 1082 1089 PF00069 0.406
MOD_GSK3_1 1195 1202 PF00069 0.567
MOD_GSK3_1 1221 1228 PF00069 0.487
MOD_GSK3_1 1230 1237 PF00069 0.459
MOD_GSK3_1 1376 1383 PF00069 0.487
MOD_GSK3_1 1411 1418 PF00069 0.547
MOD_GSK3_1 1462 1469 PF00069 0.482
MOD_GSK3_1 230 237 PF00069 0.393
MOD_GSK3_1 238 245 PF00069 0.394
MOD_GSK3_1 274 281 PF00069 0.397
MOD_GSK3_1 384 391 PF00069 0.460
MOD_GSK3_1 532 539 PF00069 0.460
MOD_GSK3_1 750 757 PF00069 0.530
MOD_GSK3_1 801 808 PF00069 0.451
MOD_GSK3_1 826 833 PF00069 0.479
MOD_GSK3_1 85 92 PF00069 0.452
MOD_GSK3_1 868 875 PF00069 0.410
MOD_GSK3_1 888 895 PF00069 0.554
MOD_GSK3_1 978 985 PF00069 0.385
MOD_LATS_1 1252 1258 PF00433 0.476
MOD_LATS_1 1325 1331 PF00433 0.537
MOD_N-GLC_1 1204 1209 PF02516 0.325
MOD_N-GLC_1 1252 1257 PF02516 0.276
MOD_N-GLC_1 1394 1399 PF02516 0.362
MOD_N-GLC_1 1466 1471 PF02516 0.293
MOD_N-GLC_1 147 152 PF02516 0.510
MOD_N-GLC_1 727 732 PF02516 0.390
MOD_N-GLC_1 978 983 PF02516 0.477
MOD_NEK2_1 1000 1005 PF00069 0.580
MOD_NEK2_1 1053 1058 PF00069 0.526
MOD_NEK2_1 11 16 PF00069 0.388
MOD_NEK2_1 1182 1187 PF00069 0.528
MOD_NEK2_1 1221 1226 PF00069 0.476
MOD_NEK2_1 1281 1286 PF00069 0.476
MOD_NEK2_1 1376 1381 PF00069 0.562
MOD_NEK2_1 1439 1444 PF00069 0.562
MOD_NEK2_1 147 152 PF00069 0.395
MOD_NEK2_1 1509 1514 PF00069 0.482
MOD_NEK2_1 1574 1579 PF00069 0.519
MOD_NEK2_1 238 243 PF00069 0.416
MOD_NEK2_1 254 259 PF00069 0.451
MOD_NEK2_1 297 302 PF00069 0.420
MOD_NEK2_1 472 477 PF00069 0.368
MOD_NEK2_1 512 517 PF00069 0.448
MOD_NEK2_1 711 716 PF00069 0.596
MOD_NEK2_1 727 732 PF00069 0.263
MOD_NEK2_1 744 749 PF00069 0.330
MOD_NEK2_1 824 829 PF00069 0.421
MOD_NEK2_1 982 987 PF00069 0.320
MOD_NEK2_2 1521 1526 PF00069 0.562
MOD_NEK2_2 259 264 PF00069 0.382
MOD_NEK2_2 610 615 PF00069 0.571
MOD_NEK2_2 762 767 PF00069 0.517
MOD_PIKK_1 1295 1301 PF00454 0.476
MOD_PIKK_1 1374 1380 PF00454 0.495
MOD_PIKK_1 242 248 PF00454 0.448
MOD_PIKK_1 289 295 PF00454 0.501
MOD_PIKK_1 524 530 PF00454 0.597
MOD_PK_1 248 254 PF00069 0.487
MOD_PK_1 826 832 PF00069 0.521
MOD_PKA_1 1009 1015 PF00069 0.663
MOD_PKA_1 1327 1333 PF00069 0.537
MOD_PKA_1 1463 1469 PF00069 0.562
MOD_PKA_1 825 831 PF00069 0.444
MOD_PKA_2 1009 1015 PF00069 0.595
MOD_PKA_2 1182 1188 PF00069 0.537
MOD_PKA_2 1327 1333 PF00069 0.537
MOD_PKA_2 1462 1468 PF00069 0.562
MOD_PKA_2 198 204 PF00069 0.444
MOD_PKA_2 246 252 PF00069 0.519
MOD_PKA_2 289 295 PF00069 0.440
MOD_PKA_2 334 340 PF00069 0.493
MOD_PKA_2 694 700 PF00069 0.593
MOD_PKA_2 750 756 PF00069 0.465
MOD_PKA_2 762 768 PF00069 0.214
MOD_PKA_2 824 830 PF00069 0.417
MOD_PKB_1 1008 1016 PF00069 0.670
MOD_PKB_1 1181 1189 PF00069 0.562
MOD_Plk_1 1193 1199 PF00069 0.476
MOD_Plk_1 1273 1279 PF00069 0.562
MOD_Plk_1 1295 1301 PF00069 0.476
MOD_Plk_1 1394 1400 PF00069 0.562
MOD_Plk_1 1415 1421 PF00069 0.476
MOD_Plk_1 259 265 PF00069 0.364
MOD_Plk_1 310 316 PF00069 0.413
MOD_Plk_1 472 478 PF00069 0.388
MOD_Plk_1 512 518 PF00069 0.524
MOD_Plk_1 711 717 PF00069 0.552
MOD_Plk_1 836 842 PF00069 0.579
MOD_Plk_1 850 856 PF00069 0.574
MOD_Plk_1 923 929 PF00069 0.595
MOD_Plk_1 978 984 PF00069 0.475
MOD_Plk_2-3 1274 1280 PF00069 0.562
MOD_Plk_2-3 890 896 PF00069 0.598
MOD_Plk_2-3 923 929 PF00069 0.605
MOD_Plk_4 1053 1059 PF00069 0.523
MOD_Plk_4 11 17 PF00069 0.469
MOD_Plk_4 1139 1145 PF00069 0.374
MOD_Plk_4 1195 1201 PF00069 0.498
MOD_Plk_4 1207 1213 PF00069 0.449
MOD_Plk_4 1221 1227 PF00069 0.468
MOD_Plk_4 1234 1240 PF00069 0.476
MOD_Plk_4 1327 1333 PF00069 0.537
MOD_Plk_4 1521 1527 PF00069 0.539
MOD_Plk_4 234 240 PF00069 0.415
MOD_Plk_4 267 273 PF00069 0.484
MOD_Plk_4 421 427 PF00069 0.571
MOD_Plk_4 536 542 PF00069 0.424
MOD_Plk_4 579 585 PF00069 0.363
MOD_Plk_4 762 768 PF00069 0.413
MOD_Plk_4 826 832 PF00069 0.538
MOD_Plk_4 92 98 PF00069 0.520
MOD_Plk_4 935 941 PF00069 0.385
MOD_ProDKin_1 1466 1472 PF00069 0.476
MOD_ProDKin_1 192 198 PF00069 0.574
MOD_ProDKin_1 302 308 PF00069 0.491
MOD_ProDKin_1 379 385 PF00069 0.426
MOD_ProDKin_1 868 874 PF00069 0.379
MOD_SUMO_for_1 1058 1061 PF00179 0.389
MOD_SUMO_rev_2 1121 1130 PF00179 0.442
MOD_SUMO_rev_2 18 23 PF00179 0.445
MOD_SUMO_rev_2 354 358 PF00179 0.493
MOD_SUMO_rev_2 747 756 PF00179 0.491
MOD_SUMO_rev_2 85 93 PF00179 0.514
MOD_SUMO_rev_2 970 976 PF00179 0.505
TRG_DiLeu_BaEn_1 646 651 PF01217 0.397
TRG_DiLeu_BaEn_2 135 141 PF01217 0.412
TRG_DiLeu_BaEn_2 567 573 PF01217 0.344
TRG_DiLeu_BaEn_4 260 266 PF01217 0.511
TRG_ENDOCYTIC_2 1067 1070 PF00928 0.340
TRG_ENDOCYTIC_2 1119 1122 PF00928 0.443
TRG_ENDOCYTIC_2 1144 1147 PF00928 0.396
TRG_ENDOCYTIC_2 1297 1300 PF00928 0.476
TRG_ENDOCYTIC_2 1338 1341 PF00928 0.476
TRG_ENDOCYTIC_2 1398 1401 PF00928 0.487
TRG_ENDOCYTIC_2 1503 1506 PF00928 0.487
TRG_ENDOCYTIC_2 1526 1529 PF00928 0.537
TRG_ENDOCYTIC_2 1548 1551 PF00928 0.487
TRG_ENDOCYTIC_2 236 239 PF00928 0.466
TRG_ENDOCYTIC_2 29 32 PF00928 0.336
TRG_ENDOCYTIC_2 467 470 PF00928 0.374
TRG_ENDOCYTIC_2 480 483 PF00928 0.376
TRG_ENDOCYTIC_2 492 495 PF00928 0.381
TRG_ENDOCYTIC_2 548 551 PF00928 0.372
TRG_ENDOCYTIC_2 634 637 PF00928 0.419
TRG_ENDOCYTIC_2 683 686 PF00928 0.450
TRG_ER_diArg_1 1008 1010 PF00400 0.617
TRG_ER_diArg_1 1109 1112 PF00400 0.470
TRG_ER_diArg_1 1127 1130 PF00400 0.263
TRG_ER_diArg_1 1179 1181 PF00400 0.562
TRG_ER_diArg_1 191 193 PF00400 0.523
TRG_ER_diArg_1 209 211 PF00400 0.227
TRG_ER_diArg_1 443 445 PF00400 0.544
TRG_ER_diArg_1 464 466 PF00400 0.482
TRG_ER_diArg_1 477 479 PF00400 0.257
TRG_ER_diArg_1 508 510 PF00400 0.509
TRG_ER_diArg_1 573 575 PF00400 0.379
TRG_ER_diArg_1 707 709 PF00400 0.603
TRG_ER_diArg_1 834 836 PF00400 0.530
TRG_ER_diArg_1 860 862 PF00400 0.368
TRG_NES_CRM1_1 206 222 PF08389 0.378
TRG_NLS_MonoExtC_3 1091 1096 PF00514 0.605
TRG_NLS_MonoExtN_4 1035 1042 PF00514 0.559
TRG_NLS_MonoExtN_4 1090 1096 PF00514 0.591
TRG_Pf-PMV_PEXEL_1 1374 1378 PF00026 0.341
TRG_Pf-PMV_PEXEL_1 1388 1392 PF00026 0.207
TRG_Pf-PMV_PEXEL_1 1571 1575 PF00026 0.505
TRG_Pf-PMV_PEXEL_1 256 260 PF00026 0.437
TRG_Pf-PMV_PEXEL_1 403 407 PF00026 0.595
TRG_Pf-PMV_PEXEL_1 445 449 PF00026 0.568
TRG_Pf-PMV_PEXEL_1 466 471 PF00026 0.389
TRG_Pf-PMV_PEXEL_1 658 662 PF00026 0.385
TRG_Pf-PMV_PEXEL_1 709 713 PF00026 0.629

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P566 Leptomonas seymouri 84% 96%
A0A0S4IR82 Bodo saltans 45% 92%
A0A1X0NJI0 Trypanosomatidae 67% 97%
A0A3Q8I9M8 Leishmania donovani 97% 100%
A0A3R7N472 Trypanosoma rangeli 68% 97%
A4H7F3 Leishmania braziliensis 93% 100%
A4HVU1 Leishmania infantum 97% 100%
D0A6E4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 66% 97%
Q4QFZ1 Leishmania major 96% 100%
V5BM10 Trypanosoma cruzi 67% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS