Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9API4_LEIMU

TriTrypDb:

LmxM.13.1600

Length:

1212

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	1
GO:0016020	membrane	2	6
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	6

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Expansion

Sequence features

E9API4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9API4

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1000	1004	PF00656	0.469
CLV_C14_Caspase3-7	238	242	PF00656	0.489
CLV_C14_Caspase3-7	769	773	PF00656	0.410
CLV_NRD_NRD_1	180	182	PF00675	0.657
CLV_NRD_NRD_1	269	271	PF00675	0.665
CLV_NRD_NRD_1	391	393	PF00675	0.661
CLV_NRD_NRD_1	706	708	PF00675	0.677
CLV_NRD_NRD_1	882	884	PF00675	0.617
CLV_NRD_NRD_1	925	927	PF00675	0.562
CLV_PCSK_FUR_1	880	884	PF00082	0.605

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P568	Leptomonas seymouri	44%	88%
A0A3Q8I9Q1	Leishmania donovani	90%	100%
A4H7F0	Leishmania braziliensis	74%	100%
A4HVT8	Leishmania infantum	90%	100%
Q4QFZ4	Leishmania major	88%	100%

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