Putative phosphoprotein phosphatase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

phosphoprotein phosphatase, putative

Species:

Leishmania mexicana

UniProt:

E9APH5_LEIMU

TriTrypDb:

LmxM.13.1510

Length:

432

Annotations

LeishMANIAdb annotations

A large collection of various protein phosphatases. Very highly expanded in kinetoplastids.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 17
NetGPI	no	yes: 0, no: 17

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005737	cytoplasm	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9APH5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9APH5

Function

Biological processes
Term	Name	Level	Count
GO:0000724	double-strand break repair via homologous recombination	7	2
GO:0000725	recombinational repair	6	2
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006259	DNA metabolic process	4	2
GO:0006281	DNA repair	5	2
GO:0006302	double-strand break repair	6	2
GO:0006310	DNA recombination	5	2
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0006950	response to stress	2	2
GO:0006974	DNA damage response	4	2
GO:0008152	metabolic process	1	2
GO:0009987	cellular process	1	2
GO:0033554	cellular response to stress	3	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0043170	macromolecule metabolic process	3	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0044260	obsolete cellular macromolecule metabolic process	3	2
GO:0046483	heterocycle metabolic process	3	2
GO:0050896	response to stimulus	1	2
GO:0051716	cellular response to stimulus	2	2
GO:0071704	organic substance metabolic process	2	2
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	18
GO:0004721	phosphoprotein phosphatase activity	3	17
GO:0004722	protein serine/threonine phosphatase activity	4	17
GO:0016787	hydrolase activity	2	18
GO:0016788	hydrolase activity, acting on ester bonds	3	17
GO:0016791	phosphatase activity	5	17
GO:0017018	myosin phosphatase activity	5	17
GO:0042578	phosphoric ester hydrolase activity	4	17
GO:0140096	catalytic activity, acting on a protein	2	17

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	104	108	PF00656	0.665
CLV_NRD_NRD_1	175	177	PF00675	0.417
CLV_NRD_NRD_1	402	404	PF00675	0.314
CLV_NRD_NRD_1	420	422	PF00675	0.622
CLV_NRD_NRD_1	91	93	PF00675	0.481
CLV_PCSK_KEX2_1	174	176	PF00082	0.415
CLV_PCSK_KEX2_1	402	404	PF00082	0.311
CLV_PCSK_KEX2_1	91	93	PF00082	0.463
CLV_PCSK_SKI1_1	185	189	PF00082	0.303
CLV_PCSK_SKI1_1	257	261	PF00082	0.471
CLV_PCSK_SKI1_1	374	378	PF00082	0.321
DOC_ANK_TNKS_1	175	182	PF00023	0.340
DOC_CYCLIN_yCln2_LP_2	260	266	PF00134	0.417
DOC_MAPK_MEF2A_6	195	204	PF00069	0.341
DOC_MAPK_MEF2A_6	257	264	PF00069	0.417
DOC_MAPK_NFAT4_5	257	265	PF00069	0.417
DOC_PP2B_LxvP_1	260	263	PF13499	0.417
DOC_PP4_FxxP_1	379	382	PF00568	0.316
DOC_PP4_FxxP_1	73	76	PF00568	0.262
DOC_SPAK_OSR1_1	274	278	PF12202	0.417
DOC_USP7_MATH_1	13	17	PF00917	0.678
DOC_USP7_MATH_1	19	23	PF00917	0.658
DOC_USP7_MATH_1	341	345	PF00917	0.424
DOC_USP7_MATH_1	412	416	PF00917	0.418
DOC_USP7_MATH_1	417	421	PF00917	0.419
DOC_WW_Pin1_4	22	27	PF00397	0.602
DOC_WW_Pin1_4	280	285	PF00397	0.318
DOC_WW_Pin1_4	3	8	PF00397	0.597
DOC_WW_Pin1_4	52	57	PF00397	0.616
LIG_14-3-3_CanoR_1	195	201	PF00244	0.399
LIG_14-3-3_CanoR_1	274	284	PF00244	0.391
LIG_14-3-3_CanoR_1	297	305	PF00244	0.275
LIG_14-3-3_CanoR_1	374	379	PF00244	0.383
LIG_BIR_II_1	1	5	PF00653	0.731
LIG_BRCT_BRCA1_1	343	347	PF00533	0.374
LIG_BRCT_BRCA1_1	78	82	PF00533	0.519
LIG_Clathr_ClatBox_1	139	143	PF01394	0.395
LIG_FAT_LD_1	200	208	PF03623	0.176
LIG_FHA_1	128	134	PF00498	0.417
LIG_FHA_1	147	153	PF00498	0.338
LIG_FHA_1	163	169	PF00498	0.132
LIG_FHA_1	227	233	PF00498	0.313
LIG_FHA_1	238	244	PF00498	0.319
LIG_FHA_1	312	318	PF00498	0.424
LIG_FHA_2	304	310	PF00498	0.375
LIG_FHA_2	368	374	PF00498	0.484
LIG_Integrin_RGD_1	95	97	PF01839	0.528
LIG_IRF3_LxIS_1	5	11	PF10401	0.501
LIG_LIR_Apic_2	377	382	PF02991	0.312
LIG_LIR_Apic_2	71	76	PF02991	0.257
LIG_LIR_Gen_1	162	172	PF02991	0.430
LIG_LIR_Gen_1	183	193	PF02991	0.319
LIG_LIR_Gen_1	249	260	PF02991	0.326
LIG_LIR_Gen_1	270	277	PF02991	0.429
LIG_LIR_Gen_1	350	359	PF02991	0.367
LIG_LIR_Gen_1	424	431	PF02991	0.493
LIG_LIR_LC3C_4	148	152	PF02991	0.339
LIG_LIR_Nem_3	162	167	PF02991	0.393
LIG_LIR_Nem_3	212	216	PF02991	0.360
LIG_LIR_Nem_3	230	236	PF02991	0.181
LIG_LIR_Nem_3	249	255	PF02991	0.300
LIG_LIR_Nem_3	270	275	PF02991	0.398
LIG_LIR_Nem_3	350	356	PF02991	0.413
LIG_LIR_Nem_3	79	85	PF02991	0.522
LIG_LYPXL_yS_3	213	216	PF13949	0.361
LIG_MAD2	374	382	PF02301	0.370
LIG_PCNA_PIPBox_1	361	370	PF02747	0.369
LIG_PCNA_yPIPBox_3	358	368	PF02747	0.412
LIG_PTB_Apo_2	115	122	PF02174	0.403
LIG_PTB_Phospho_1	115	121	PF10480	0.411
LIG_SH2_CRK	164	168	PF00017	0.432
LIG_SH2_CRK	233	237	PF00017	0.391
LIG_SH2_CRK	384	388	PF00017	0.471
LIG_SH2_STAP1	164	168	PF00017	0.417
LIG_SH2_STAP1	427	431	PF00017	0.380
LIG_SH2_STAT5	121	124	PF00017	0.473
LIG_SH2_STAT5	164	167	PF00017	0.417
LIG_SH2_STAT5	192	195	PF00017	0.303
LIG_SH2_STAT5	218	221	PF00017	0.391
LIG_SH2_STAT5	367	370	PF00017	0.424
LIG_SH2_STAT5	384	387	PF00017	0.323
LIG_SH3_3	131	137	PF00018	0.325
LIG_SH3_3	208	214	PF00018	0.319
LIG_SUMO_SIM_anti_2	141	146	PF11976	0.409
LIG_SUMO_SIM_anti_2	148	155	PF11976	0.263
LIG_SUMO_SIM_anti_2	199	204	PF11976	0.282
LIG_SUMO_SIM_par_1	130	136	PF11976	0.434
LIG_SUMO_SIM_par_1	138	143	PF11976	0.387
LIG_SUMO_SIM_par_1	148	155	PF11976	0.248
LIG_SUMO_SIM_par_1	373	380	PF11976	0.333
LIG_SUMO_SIM_par_1	6	12	PF11976	0.570
LIG_TRAF2_1	288	291	PF00917	0.176
LIG_TYR_ITIM	211	216	PF00017	0.361
LIG_UBA3_1	203	210	PF00899	0.292
LIG_WW_3	75	79	PF00397	0.292
MOD_CDK_SPxxK_3	22	29	PF00069	0.553
MOD_CK1_1	22	28	PF00069	0.743
MOD_CK1_1	319	325	PF00069	0.347
MOD_CK1_1	36	42	PF00069	0.674
MOD_CK1_1	51	57	PF00069	0.600
MOD_CK2_1	285	291	PF00069	0.256
MOD_CK2_1	303	309	PF00069	0.430
MOD_GlcNHglycan	252	255	PF01048	0.423
MOD_GlcNHglycan	301	304	PF01048	0.260
MOD_GlcNHglycan	341	344	PF01048	0.461
MOD_GlcNHglycan	379	382	PF01048	0.366
MOD_GlcNHglycan	410	413	PF01048	0.425
MOD_GlcNHglycan	73	76	PF01048	0.488
MOD_GlcNHglycan	78	81	PF01048	0.459
MOD_GSK3_1	101	108	PF00069	0.515
MOD_GSK3_1	234	241	PF00069	0.467
MOD_GSK3_1	246	253	PF00069	0.349
MOD_GSK3_1	299	306	PF00069	0.380
MOD_GSK3_1	33	40	PF00069	0.660
MOD_GSK3_1	408	415	PF00069	0.384
MOD_GSK3_1	47	54	PF00069	0.617
MOD_GSK3_1	8	15	PF00069	0.699
MOD_N-GLC_1	298	303	PF02516	0.279
MOD_N-GLC_2	383	385	PF02516	0.354
MOD_NEK2_1	101	106	PF00069	0.548
MOD_NEK2_1	163	168	PF00069	0.457
MOD_NEK2_1	275	280	PF00069	0.335
MOD_NEK2_1	35	40	PF00069	0.718
MOD_NEK2_2	19	24	PF00069	0.573
MOD_PIKK_1	101	107	PF00454	0.653
MOD_PIKK_1	109	115	PF00454	0.586
MOD_PIKK_1	33	39	PF00454	0.539
MOD_PKA_2	17	23	PF00069	0.696
MOD_Plk_1	47	53	PF00069	0.562
MOD_Plk_2-3	291	297	PF00069	0.421
MOD_Plk_2-3	66	72	PF00069	0.349
MOD_Plk_4	112	118	PF00069	0.446
MOD_Plk_4	128	134	PF00069	0.311
MOD_Plk_4	146	152	PF00069	0.376
MOD_Plk_4	163	169	PF00069	0.417
MOD_Plk_4	212	218	PF00069	0.451
MOD_Plk_4	267	273	PF00069	0.462
MOD_Plk_4	374	380	PF00069	0.308
MOD_Plk_4	38	44	PF00069	0.641
MOD_ProDKin_1	22	28	PF00069	0.603
MOD_ProDKin_1	280	286	PF00069	0.318
MOD_ProDKin_1	3	9	PF00069	0.598
MOD_ProDKin_1	52	58	PF00069	0.639
MOD_SUMO_for_1	209	212	PF00179	0.289
MOD_SUMO_rev_2	225	230	PF00179	0.340
MOD_SUMO_rev_2	6	16	PF00179	0.699
TRG_DiLeu_BaEn_1	135	140	PF01217	0.325
TRG_DiLeu_BaEn_1	201	206	PF01217	0.276
TRG_DiLeu_BaEn_1	212	217	PF01217	0.314
TRG_DiLeu_BaEn_4	135	141	PF01217	0.355
TRG_DiLeu_BaLyEn_6	81	86	PF01217	0.353
TRG_ENDOCYTIC_2	164	167	PF00928	0.432
TRG_ENDOCYTIC_2	213	216	PF00928	0.361
TRG_ENDOCYTIC_2	233	236	PF00928	0.132
TRG_ENDOCYTIC_2	272	275	PF00928	0.403
TRG_ENDOCYTIC_2	384	387	PF00928	0.369
TRG_ENDOCYTIC_2	427	430	PF00928	0.410
TRG_ER_diArg_1	174	176	PF00400	0.415
TRG_ER_diArg_1	28	31	PF00400	0.525
TRG_ER_diArg_1	402	404	PF00400	0.311
TRG_ER_diArg_1	90	92	PF00400	0.462
TRG_NES_CRM1_1	201	212	PF08389	0.197

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7Y2	Leptomonas seymouri	32%	79%
A0A0N1HSR2	Leptomonas seymouri	32%	100%
A0A0N1I0V3	Leptomonas seymouri	34%	100%
A0A0N1I548	Leptomonas seymouri	34%	68%
A0A0N1IBK9	Leptomonas seymouri	38%	100%
A0A0N1ILH2	Leptomonas seymouri	32%	100%
A0A0N1PAV9	Leptomonas seymouri	35%	100%
A0A0N1PBN9	Leptomonas seymouri	33%	92%
A0A0N1PDK9	Leptomonas seymouri	36%	100%
A0A0S4IIW0	Bodo saltans	32%	100%
A0A0S4ILF8	Bodo saltans	38%	100%
A0A0S4IS15	Bodo saltans	45%	90%
A0A0S4IYE4	Bodo saltans	32%	78%
A0A0S4J1J1	Bodo saltans	44%	100%
A0A0S4J323	Bodo saltans	37%	75%
A0A0S4JDD1	Bodo saltans	32%	96%
A0A0S4JJ52	Bodo saltans	36%	100%
A0A0S4JKZ6	Bodo saltans	35%	87%
A0A0S4JP77	Bodo saltans	32%	68%
A0A0S4KGD7	Bodo saltans	37%	100%
A0A1X0NJI7	Trypanosomatidae	51%	78%
A0A1X0NMS7	Trypanosomatidae	26%	100%
A0A1X0NNN6	Trypanosomatidae	37%	100%
A0A1X0NPA5	Trypanosomatidae	33%	67%
A0A1X0NUA6	Trypanosomatidae	31%	100%
A0A1X0P2R2	Trypanosomatidae	33%	68%
A0A1X0P6J3	Trypanosomatidae	34%	100%
A0A1X0P7H9	Trypanosomatidae	31%	97%
A0A1X0P7Q5	Trypanosomatidae	32%	100%
A0A1X0P982	Trypanosomatidae	36%	100%
A0A1X0P9R6	Trypanosomatidae	38%	95%
A0A3Q8I8M6	Leishmania donovani	86%	100%
A0A3Q8ID20	Leishmania donovani	31%	90%
A0A3Q8IFB2	Leishmania donovani	34%	100%
A0A3Q8IH18	Leishmania donovani	38%	100%
A0A3Q8II54	Leishmania donovani	68%	74%
A0A3R7M399	Trypanosoma rangeli	38%	99%
A0A3R7MBA3	Trypanosoma rangeli	30%	96%
A0A3R7MFZ7	Trypanosoma rangeli	34%	100%
A0A3R7MM48	Trypanosoma rangeli	32%	100%
A0A3R7NXP6	Trypanosoma rangeli	34%	67%
A0A3S5H5F8	Leishmania donovani	35%	68%
A0A3S5H6D4	Leishmania donovani	32%	66%
A0A3S5H6T9	Leishmania donovani	32%	100%
A0A3S5H7Q6	Leishmania donovani	34%	100%
A0A3S7WZ39	Leishmania donovani	35%	100%
A0A3S7X190	Leishmania donovani	37%	100%
A0A3S7X1Y0	Leishmania donovani	35%	100%
A0A3S7X7I6	Leishmania donovani	30%	100%
A0A3S7X7J8	Leishmania donovani	34%	100%
A0A3S7X7K2	Leishmania donovani	34%	100%
A0A3S7X8K6	Leishmania donovani	34%	100%
A0A3S7XAY3	Leishmania donovani	31%	100%
A0A422N1U7	Trypanosoma rangeli	31%	72%
A0A422N9D5	Trypanosoma rangeli	33%	100%
A0A422NKG0	Trypanosoma rangeli	36%	100%
A0A422NYB5	Trypanosoma rangeli	33%	68%
A0A422P483	Trypanosoma rangeli	48%	100%
A0C1E4	Paramecium tetraurelia	36%	100%
A0CCD2	Paramecium tetraurelia	38%	100%
A2XN40	Oryza sativa subsp. indica	35%	100%
A3C4N5	Oryza sativa subsp. japonica	35%	100%
A4H456	Leishmania braziliensis	35%	68%
A4H5M4	Leishmania braziliensis	33%	67%
A4H7D2	Leishmania braziliensis	72%	100%
A4H7E7	Leishmania braziliensis	73%	74%
A4H7Z3	Leishmania braziliensis	31%	100%
A4HAI7	Leishmania braziliensis	33%	100%
A4HAI8	Leishmania braziliensis	33%	94%
A4HAI9	Leishmania braziliensis	33%	100%
A4HAJ8	Leishmania braziliensis	34%	100%
A4HBE2	Leishmania braziliensis	35%	100%
A4HF98	Leishmania braziliensis	32%	79%
A4HGA9	Leishmania braziliensis	36%	100%
A4HJQ1	Leishmania braziliensis	34%	100%
A4HKU9	Leishmania braziliensis	38%	100%
A4HP65	Leishmania braziliensis	32%	100%
A4HSD9	Leishmania infantum	35%	68%
A4HTW1	Leishmania infantum	32%	66%
A4HVT0	Leishmania infantum	86%	100%
A4HVT6	Leishmania infantum	69%	74%
A4HWC1	Leishmania infantum	32%	100%
A4I1H6	Leishmania infantum	35%	100%
A4I2J0	Leishmania infantum	31%	90%
A4I3E3	Leishmania infantum	37%	100%
A4I400	Leishmania infantum	35%	100%
A4I768	Leishmania infantum	35%	100%
A4I8C8	Leishmania infantum	38%	100%
A4I9P2	Leishmania infantum	34%	100%
A4IAJ0	Leishmania infantum	34%	100%
A4IDH0	Leishmania infantum	31%	100%
A6H772	Bos taurus	38%	100%
A8WGP3	Danio rerio	38%	100%
A8XE00	Caenorhabditis briggsae	38%	100%
A9JRC7	Danio rerio	37%	100%
C9ZM48	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZN02	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
C9ZN06	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
C9ZPX4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	68%
C9ZX13	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
D0A358	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
D0A366	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	68%
D0A9C5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	68%
E9AHS9	Leishmania infantum	35%	100%
E9AHT0	Leishmania infantum	34%	100%
E9AHT1	Leishmania infantum	31%	100%
E9AKB4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	68%
E9AMP8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	66%
E9API1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	73%
E9AQ21	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9ASX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AXL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
E9AYN4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	86%
E9AZN0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
E9B090	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B262	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B387	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9B4P8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B4P9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9B4Q0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9B4Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B4Q6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B5L4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
O00743	Homo sapiens	35%	100%
O04860	Nicotiana tabacum	38%	100%
O14829	Homo sapiens	26%	66%
O35655	Mus musculus	27%	66%
O42773	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)	34%	68%
O74789	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	100%
O76932	Drosophila melanogaster	38%	100%
P0C5D7	Oryza sativa subsp. indica	35%	100%
P11084	Oryctolagus cuniculus	38%	100%
P13681	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	100%
P14747	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	72%
P16298	Homo sapiens	32%	82%
P20651	Rattus norvegicus	32%	82%
P23287	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	78%
P23594	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	100%
P23595	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	100%
P23635	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	100%
P23696	Drosophila melanogaster	37%	100%
P23778	Brassica napus	35%	100%
P32345	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	100%
P32838	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	100%
P32945	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	79%
P34350	Caenorhabditis elegans	26%	100%
P36614	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
P48452	Bos taurus	32%	83%
P48453	Mus musculus	32%	82%
P48454	Homo sapiens	33%	84%
P48455	Mus musculus	33%	84%
P48456	Drosophila melanogaster	33%	69%
P48457	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	35%	79%
P48459	Caenorhabditis elegans	33%	95%
P48460	Caenorhabditis elegans	34%	95%
P48461	Drosophila melanogaster	37%	100%
P48528	Arabidopsis thaliana	39%	100%
P48577	Acetabularia peniculus	36%	100%
P48578	Arabidopsis thaliana	35%	100%
P48579	Helianthus annuus	38%	100%
P49576	Paramecium tetraurelia	35%	100%
P53041	Homo sapiens	35%	87%
P53042	Rattus norvegicus	34%	87%
P53043	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	84%
P60510	Homo sapiens	38%	100%
P63328	Mus musculus	32%	83%
P63329	Rattus norvegicus	32%	83%
P97470	Mus musculus	38%	100%
Q05681	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	34%	77%
Q06009	Medicago sativa	35%	100%
Q07100	Arabidopsis thaliana	35%	100%
Q08209	Homo sapiens	32%	83%
Q09496	Caenorhabditis elegans	32%	100%
Q0G819	Caenorhabditis elegans	31%	80%
Q10298	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
Q10BT5	Oryza sativa subsp. japonica	35%	100%
Q12705	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	78%
Q27884	Drosophila melanogaster	37%	100%
Q3SWT6	Rattus norvegicus	27%	68%
Q4Q1M5	Leishmania major	31%	100%
Q4Q2C2	Leishmania major	35%	100%
Q4Q3C0	Leishmania major	36%	100%
Q4Q3C5	Leishmania major	30%	94%
Q4Q3C6	Leishmania major	34%	100%
Q4Q3C7	Leishmania major	34%	100%
Q4Q3C8	Leishmania major	33%	100%
Q4Q4W8	Leishmania major	38%	100%
Q4Q5Z8	Leishmania major	35%	100%
Q4Q7Z5	Leishmania major	35%	100%
Q4Q8K1	Leishmania major	37%	100%
Q4Q8T8	Leishmania major	30%	87%
Q4Q9W1	Leishmania major	35%	98%
Q4QFG0	Leishmania major	32%	100%
Q4QFZ7	Leishmania major	68%	100%
Q4QG03	Leishmania major	85%	100%
Q4QHX7	Leishmania major	33%	66%
Q4QJJ3	Leishmania major	35%	68%
Q4WUR1	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	35%	81%
Q5A6B6	Candida albicans (strain SC5314 / ATCC MYA-2876)	38%	100%
Q5BJ92	Rattus norvegicus	37%	100%
Q5R6K8	Pongo abelii	38%	100%
Q60676	Mus musculus	34%	87%
Q64620	Rattus norvegicus	35%	100%
Q6FM81	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	36%	100%
Q6IP91	Xenopus laevis	38%	100%
Q6P861	Xenopus tropicalis	38%	100%
Q7YSW8	Dictyostelium discoideum	34%	69%
Q84K11	Solanum lycopersicum	33%	78%
Q84XU2	Arabidopsis thaliana	34%	80%
Q9CQR6	Mus musculus	35%	100%
Q9FN02	Arabidopsis thaliana	33%	100%
Q9NES8	Caenorhabditis elegans	32%	87%
Q9VXF1	Drosophila melanogaster	32%	74%
Q9XGH7	Nicotiana tabacum	35%	100%
Q9XW79	Caenorhabditis elegans	37%	100%
Q9Y0B7	Dictyostelium discoideum	35%	100%
V5AUW3	Trypanosoma cruzi	33%	100%
V5B3V2	Trypanosoma cruzi	31%	100%
V5BAC7	Trypanosoma cruzi	33%	68%
V5BBR3	Trypanosoma cruzi	31%	100%
V5BBS3	Trypanosoma cruzi	32%	72%
V5BGM0	Trypanosoma cruzi	31%	100%
V5BQD7	Trypanosoma cruzi	44%	99%
V5D2G9	Trypanosoma cruzi	34%	100%
V5DCW3	Trypanosoma cruzi	36%	100%
V5DIG8	Trypanosoma cruzi	44%	100%