LeishMANIAdb
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Protein kinase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9APG5_LEIMU
TriTrypDb:
LmxM.13.1410
Length:
1250

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9APG5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9APG5

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1036 1040 PF00656 0.527
CLV_C14_Caspase3-7 312 316 PF00656 0.828
CLV_C14_Caspase3-7 462 466 PF00656 0.551
CLV_NRD_NRD_1 150 152 PF00675 0.559
CLV_NRD_NRD_1 246 248 PF00675 0.824
CLV_NRD_NRD_1 771 773 PF00675 0.835
CLV_NRD_NRD_1 88 90 PF00675 0.672
CLV_PCSK_KEX2_1 150 152 PF00082 0.559
CLV_PCSK_KEX2_1 245 247 PF00082 0.818
CLV_PCSK_KEX2_1 773 775 PF00082 0.838
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S7WSN6 Leishmania donovani 72% 100%
A4H7C3 Leishmania braziliensis 50% 98%
A4HVR9 Leishmania infantum 72% 100%
Q4QG13 Leishmania major 72% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS