Complex1_LYR_dom domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Complex 1 protein (LYR family), putative

Species:

Leishmania mexicana

UniProt:

E9APF4_LEIMU

TriTrypDb:

LmxM.13.1300

Length:

196

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9APF4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9APF4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	113	115	PF00675	0.373
CLV_NRD_NRD_1	121	123	PF00675	0.518
CLV_NRD_NRD_1	130	132	PF00675	0.447
CLV_NRD_NRD_1	186	188	PF00675	0.517
CLV_NRD_NRD_1	46	48	PF00675	0.291
CLV_PCSK_FUR_1	44	48	PF00082	0.325
CLV_PCSK_KEX2_1	121	123	PF00082	0.601
CLV_PCSK_KEX2_1	130	132	PF00082	0.660
CLV_PCSK_KEX2_1	186	188	PF00082	0.517
CLV_PCSK_KEX2_1	46	48	PF00082	0.291
CLV_PCSK_SKI1_1	157	161	PF00082	0.539
CLV_PCSK_SKI1_1	186	190	PF00082	0.512
CLV_PCSK_SKI1_1	32	36	PF00082	0.357
CLV_PCSK_SKI1_1	74	78	PF00082	0.291
CLV_PCSK_SKI1_1	83	87	PF00082	0.291
DEG_Nend_Nbox_1	1	3	PF02207	0.691
DOC_PP4_FxxP_1	58	61	PF00568	0.317
DOC_USP7_MATH_1	42	46	PF00917	0.300
DOC_USP7_UBL2_3	153	157	PF12436	0.557
LIG_14-3-3_CanoR_1	130	139	PF00244	0.560
LIG_14-3-3_CanoR_1	55	59	PF00244	0.385
LIG_FHA_1	131	137	PF00498	0.469
LIG_FHA_1	2	8	PF00498	0.602
LIG_FHA_1	49	55	PF00498	0.325
LIG_FHA_2	55	61	PF00498	0.385
LIG_FHA_2	85	91	PF00498	0.319
LIG_LIR_Apic_2	56	61	PF02991	0.351
LIG_LIR_Nem_3	141	146	PF02991	0.511
LIG_LIR_Nem_3	70	76	PF02991	0.331
LIG_Pex14_2	184	188	PF04695	0.524
LIG_Pex14_2	192	196	PF04695	0.501
LIG_REV1ctd_RIR_1	181	191	PF16727	0.550
LIG_SH2_CRK	31	35	PF00017	0.291
LIG_SH2_CRK	73	77	PF00017	0.325
LIG_SH2_GRB2like	143	146	PF00017	0.532
LIG_SH2_STAP1	88	92	PF00017	0.325
LIG_SH2_STAT3	22	25	PF00017	0.505
LIG_SH2_STAT5	107	110	PF00017	0.385
LIG_SH3_3	173	179	PF00018	0.560
LIG_TYR_ITIM	71	76	PF00017	0.325
MOD_CK1_1	84	90	PF00069	0.401
MOD_CK2_1	84	90	PF00069	0.340
MOD_CK2_1	94	100	PF00069	0.255
MOD_GSK3_1	130	137	PF00069	0.486
MOD_NEK2_1	1	6	PF00069	0.611
MOD_NEK2_1	139	144	PF00069	0.515
MOD_PK_1	81	87	PF00069	0.385
MOD_PKA_1	130	136	PF00069	0.483
MOD_PKA_2	130	136	PF00069	0.507
MOD_PKA_2	54	60	PF00069	0.385
MOD_Plk_2-3	48	54	PF00069	0.291
MOD_Plk_2-3	64	70	PF00069	0.325
MOD_Plk_4	139	145	PF00069	0.521
MOD_Plk_4	2	8	PF00069	0.584
MOD_SUMO_rev_2	109	117	PF00179	0.385
MOD_SUMO_rev_2	134	142	PF00179	0.562
TRG_DiLeu_BaLyEn_6	71	76	PF01217	0.307
TRG_ENDOCYTIC_2	143	146	PF00928	0.509
TRG_ENDOCYTIC_2	31	34	PF00928	0.291
TRG_ENDOCYTIC_2	73	76	PF00928	0.325
TRG_ER_diArg_1	120	122	PF00400	0.340
TRG_ER_diArg_1	129	131	PF00400	0.565
TRG_ER_diArg_1	166	169	PF00400	0.554
TRG_ER_diArg_1	185	187	PF00400	0.529
TRG_ER_diArg_1	43	46	PF00400	0.330

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I7Q9	Leptomonas seymouri	81%	100%
A0A0S4JJ94	Bodo saltans	66%	100%
A0A3Q8I9K5	Leishmania donovani	96%	100%
A4H7B3	Leishmania braziliensis	92%	100%
A4HVQ8	Leishmania infantum	96%	100%
D0A6I2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	71%	87%
Q4QG24	Leishmania major	95%	100%