LeishMANIAdb
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Mitochondrial ribosomal protein L23

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Mitochondrial ribosomal protein L23
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9APE4_LEIMU
TriTrypDb:
LmxM.13.1200
Length:
185

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9APE4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9APE4

PDB structure(s): 7aih_P , 7ane_P

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 51 53 PF00675 0.482
CLV_PCSK_KEX2_1 50 52 PF00082 0.459
CLV_PCSK_SKI1_1 117 121 PF00082 0.410
DEG_APCC_DBOX_1 136 144 PF00400 0.498
DEG_Nend_Nbox_1 1 3 PF02207 0.528
DOC_CKS1_1 36 41 PF01111 0.386
DOC_MAPK_gen_1 123 130 PF00069 0.460
DOC_PP4_FxxP_1 162 165 PF00568 0.405
DOC_WW_Pin1_4 21 26 PF00397 0.429
DOC_WW_Pin1_4 35 40 PF00397 0.336
LIG_14-3-3_CanoR_1 123 129 PF00244 0.431
LIG_14-3-3_CanoR_1 181 185 PF00244 0.484
LIG_14-3-3_CanoR_1 3 7 PF00244 0.446
LIG_FHA_1 167 173 PF00498 0.460
LIG_FHA_1 74 80 PF00498 0.390
LIG_FHA_1 81 87 PF00498 0.345
LIG_FHA_1 89 95 PF00498 0.355
LIG_FHA_2 39 45 PF00498 0.427
LIG_LIR_Apic_2 159 165 PF02991 0.408
LIG_LIR_Gen_1 97 107 PF02991 0.470
LIG_LIR_Nem_3 76 80 PF02991 0.365
LIG_LIR_Nem_3 97 103 PF02991 0.465
LIG_MYND_1 174 178 PF01753 0.502
LIG_PTB_Apo_2 92 99 PF02174 0.389
LIG_PTB_Phospho_1 92 98 PF10480 0.391
LIG_SH2_STAP1 9 13 PF00017 0.537
LIG_SH2_STAT3 58 61 PF00017 0.568
LIG_SH3_3 140 146 PF00018 0.497
LIG_SH3_3 33 39 PF00018 0.398
MOD_CDK_SPK_2 21 26 PF00069 0.565
MOD_CDK_SPxxK_3 21 28 PF00069 0.543
MOD_CDK_SPxxK_3 38 45 PF00069 0.323
MOD_CK1_1 11 17 PF00069 0.521
MOD_CK2_1 38 44 PF00069 0.401
MOD_GSK3_1 75 82 PF00069 0.411
MOD_GSK3_1 85 92 PF00069 0.387
MOD_NEK2_1 110 115 PF00069 0.554
MOD_NEK2_1 129 134 PF00069 0.460
MOD_NEK2_1 2 7 PF00069 0.420
MOD_NEK2_1 79 84 PF00069 0.392
MOD_NEK2_2 85 90 PF00069 0.352
MOD_PKA_2 2 8 PF00069 0.421
MOD_PKA_2 56 62 PF00069 0.487
MOD_PKA_2 89 95 PF00069 0.373
MOD_Plk_4 124 130 PF00069 0.454
MOD_ProDKin_1 21 27 PF00069 0.423
MOD_ProDKin_1 35 41 PF00069 0.339
TRG_ENDOCYTIC_2 98 101 PF00928 0.336
TRG_ER_diArg_1 111 114 PF00400 0.427
TRG_ER_diArg_1 50 52 PF00400 0.435

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IMF0 Leptomonas seymouri 85% 100%
A0A0S4JV89 Bodo saltans 61% 100%
A0A1X0NMX1 Trypanosomatidae 75% 100%
A0A3S7WSK9 Leishmania donovani 94% 100%
A0A422NLH3 Trypanosoma rangeli 74% 100%
A4H7A4 Leishmania braziliensis 91% 100%
A4HVP8 Leishmania infantum 94% 100%
Q4QG34 Leishmania major 94% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS