Leucine--tRNA ligase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

leucyl-tRNA synthetase, putative

Species:

Leishmania mexicana

UniProt:

E9APD4_LEIMU

TriTrypDb:

LmxM.13.1100

Length:

1075

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 2
Forrest at al. (procyclic)	no	yes: 2
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 12

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 5

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9APD4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9APD4

Function

Biological processes
Term	Name	Level	Count
GO:0006082	organic acid metabolic process	3	11
GO:0006139	nucleobase-containing compound metabolic process	3	11
GO:0006399	tRNA metabolic process	7	11
GO:0006418	tRNA aminoacylation for protein translation	6	11
GO:0006429	leucyl-tRNA aminoacylation	7	11
GO:0006520	amino acid metabolic process	3	11
GO:0006725	cellular aromatic compound metabolic process	3	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0009987	cellular process	1	11
GO:0016070	RNA metabolic process	5	11
GO:0019752	carboxylic acid metabolic process	5	11
GO:0034641	cellular nitrogen compound metabolic process	3	11
GO:0034660	ncRNA metabolic process	6	11
GO:0043038	amino acid activation	4	11
GO:0043039	tRNA aminoacylation	5	11
GO:0043170	macromolecule metabolic process	3	11
GO:0043436	oxoacid metabolic process	4	11
GO:0044237	cellular metabolic process	2	11
GO:0044238	primary metabolic process	2	11
GO:0044281	small molecule metabolic process	2	11
GO:0046483	heterocycle metabolic process	3	11
GO:0071704	organic substance metabolic process	2	11
GO:0090304	nucleic acid metabolic process	4	11
GO:1901360	organic cyclic compound metabolic process	3	11
GO:1901564	organonitrogen compound metabolic process	3	11

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0002161	aminoacyl-tRNA editing activity	5	11
GO:0003824	catalytic activity	1	11
GO:0004812	aminoacyl-tRNA ligase activity	4	11
GO:0004823	leucine-tRNA ligase activity	5	11
GO:0005488	binding	1	11
GO:0005524	ATP binding	5	11
GO:0016787	hydrolase activity	2	11
GO:0016788	hydrolase activity, acting on ester bonds	3	11
GO:0016874	ligase activity	2	11
GO:0016875	ligase activity, forming carbon-oxygen bonds	3	11
GO:0017076	purine nucleotide binding	4	11
GO:0030554	adenyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032559	adenyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0052689	carboxylic ester hydrolase activity	4	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:0140098	catalytic activity, acting on RNA	3	11
GO:0140101	catalytic activity, acting on a tRNA	4	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	599	603	PF00656	0.458
CLV_C14_Caspase3-7	760	764	PF00656	0.455
CLV_MEL_PAP_1	304	310	PF00089	0.152
CLV_NRD_NRD_1	1056	1058	PF00675	0.515
CLV_NRD_NRD_1	194	196	PF00675	0.258
CLV_NRD_NRD_1	218	220	PF00675	0.315
CLV_NRD_NRD_1	5	7	PF00675	0.410
CLV_NRD_NRD_1	77	79	PF00675	0.273
CLV_NRD_NRD_1	863	865	PF00675	0.310
CLV_NRD_NRD_1	947	949	PF00675	0.567
CLV_PCSK_KEX2_1	1056	1058	PF00082	0.515
CLV_PCSK_KEX2_1	139	141	PF00082	0.613
CLV_PCSK_KEX2_1	194	196	PF00082	0.277
CLV_PCSK_KEX2_1	218	220	PF00082	0.285
CLV_PCSK_KEX2_1	227	229	PF00082	0.227
CLV_PCSK_KEX2_1	5	7	PF00082	0.400
CLV_PCSK_KEX2_1	545	547	PF00082	0.202
CLV_PCSK_KEX2_1	77	79	PF00082	0.289
CLV_PCSK_KEX2_1	863	865	PF00082	0.310
CLV_PCSK_KEX2_1	935	937	PF00082	0.272
CLV_PCSK_KEX2_1	947	949	PF00082	0.440
CLV_PCSK_PC1ET2_1	139	141	PF00082	0.613
CLV_PCSK_PC1ET2_1	227	229	PF00082	0.258
CLV_PCSK_PC1ET2_1	545	547	PF00082	0.202
CLV_PCSK_PC1ET2_1	935	937	PF00082	0.272
CLV_PCSK_PC7_1	73	79	PF00082	0.289
CLV_PCSK_SKI1_1	316	320	PF00082	0.343
CLV_PCSK_SKI1_1	40	44	PF00082	0.307
CLV_PCSK_SKI1_1	6	10	PF00082	0.459
CLV_PCSK_SKI1_1	731	735	PF00082	0.279
CLV_PCSK_SKI1_1	831	835	PF00082	0.258
CLV_PCSK_SKI1_1	931	935	PF00082	0.247
CLV_PCSK_SKI1_1	98	102	PF00082	0.362
CLV_Separin_Metazoa	513	517	PF03568	0.538
CLV_Separin_Metazoa	959	963	PF03568	0.245
DEG_APCC_DBOX_1	5	13	PF00400	0.390
DEG_ODPH_VHL_1	370	381	PF01847	0.562
DEG_SPOP_SBC_1	967	971	PF00917	0.296
DOC_ANK_TNKS_1	244	251	PF00023	0.458
DOC_CDC14_PxL_1	435	443	PF14671	0.538
DOC_CKS1_1	121	126	PF01111	0.707
DOC_CYCLIN_yCln2_LP_2	366	372	PF00134	0.489
DOC_MAPK_DCC_7	1032	1041	PF00069	0.406
DOC_MAPK_FxFP_2	45	48	PF00069	0.458
DOC_MAPK_gen_1	316	326	PF00069	0.538
DOC_MAPK_gen_1	5	12	PF00069	0.414
DOC_MAPK_gen_1	552	558	PF00069	0.523
DOC_MAPK_gen_1	734	742	PF00069	0.458
DOC_MAPK_gen_1	863	871	PF00069	0.562
DOC_MAPK_HePTP_8	410	422	PF00069	0.509
DOC_MAPK_HePTP_8	861	873	PF00069	0.538
DOC_MAPK_JIP1_4	147	153	PF00069	0.513
DOC_MAPK_MEF2A_6	1032	1041	PF00069	0.406
DOC_MAPK_MEF2A_6	413	422	PF00069	0.550
DOC_MAPK_MEF2A_6	864	873	PF00069	0.538
DOC_MAPK_RevD_3	179	195	PF00069	0.261
DOC_PP1_RVXF_1	206	213	PF00149	0.472
DOC_PP2B_LxvP_1	366	369	PF13499	0.472
DOC_PP4_FxxP_1	166	169	PF00568	0.393
DOC_PP4_FxxP_1	28	31	PF00568	0.565
DOC_PP4_FxxP_1	45	48	PF00568	0.339
DOC_PP4_FxxP_1	900	903	PF00568	0.472
DOC_USP7_MATH_1	1071	1075	PF00917	0.492
DOC_USP7_MATH_1	620	624	PF00917	0.529
DOC_USP7_MATH_1	666	670	PF00917	0.538
DOC_USP7_MATH_1	761	765	PF00917	0.458
DOC_USP7_MATH_1	967	971	PF00917	0.510
DOC_USP7_MATH_1	994	998	PF00917	0.547
DOC_USP7_UBL2_3	419	423	PF12436	0.458
DOC_USP7_UBL2_3	540	544	PF12436	0.472
DOC_USP7_UBL2_3	931	935	PF12436	0.472
DOC_USP7_UBL2_3	986	990	PF12436	0.602
DOC_WW_Pin1_4	120	125	PF00397	0.626
DOC_WW_Pin1_4	230	235	PF00397	0.458
DOC_WW_Pin1_4	397	402	PF00397	0.458
DOC_WW_Pin1_4	87	92	PF00397	0.458
LIG_14-3-3_CanoR_1	1040	1049	PF00244	0.535
LIG_14-3-3_CanoR_1	194	198	PF00244	0.458
LIG_14-3-3_CanoR_1	307	311	PF00244	0.352
LIG_14-3-3_CanoR_1	77	81	PF00244	0.489
LIG_AP2alpha_1	205	209	PF02296	0.385
LIG_BIR_II_1	1	5	PF00653	0.462
LIG_BRCT_BRCA1_1	304	308	PF00533	0.418
LIG_BRCT_BRCA1_1	577	581	PF00533	0.489
LIG_BRCT_BRCA1_1	968	972	PF00533	0.286
LIG_Clathr_ClatBox_1	353	357	PF01394	0.443
LIG_Clathr_ClatBox_1	9	13	PF01394	0.391
LIG_CtBP_PxDLS_1	682	686	PF00389	0.458
LIG_CtBP_PxDLS_1	973	977	PF00389	0.515
LIG_deltaCOP1_diTrp_1	192	197	PF00928	0.510
LIG_deltaCOP1_diTrp_1	424	430	PF00928	0.489
LIG_deltaCOP1_diTrp_1	574	581	PF00928	0.493
LIG_deltaCOP1_diTrp_1	711	720	PF00928	0.562
LIG_EH_1	202	206	PF12763	0.385
LIG_EH1_1	255	263	PF00400	0.489
LIG_EH1_1	865	873	PF00400	0.510
LIG_eIF4E_1	256	262	PF01652	0.538
LIG_eIF4E_1	866	872	PF01652	0.510
LIG_FHA_1	1011	1017	PF00498	0.457
LIG_FHA_1	1025	1031	PF00498	0.356
LIG_FHA_1	128	134	PF00498	0.731
LIG_FHA_1	357	363	PF00498	0.508
LIG_FHA_1	388	394	PF00498	0.450
LIG_FHA_1	406	412	PF00498	0.474
LIG_FHA_1	459	465	PF00498	0.510
LIG_FHA_1	578	584	PF00498	0.458
LIG_FHA_1	592	598	PF00498	0.458
LIG_FHA_1	640	646	PF00498	0.510
LIG_FHA_1	696	702	PF00498	0.458
LIG_FHA_1	781	787	PF00498	0.375
LIG_FHA_1	902	908	PF00498	0.520
LIG_FHA_1	975	981	PF00498	0.366
LIG_FHA_2	1046	1052	PF00498	0.554
LIG_FHA_2	121	127	PF00498	0.666
LIG_FHA_2	346	352	PF00498	0.471
LIG_FHA_2	381	387	PF00498	0.472
LIG_FHA_2	496	502	PF00498	0.523
LIG_FHA_2	61	67	PF00498	0.472
LIG_FHA_2	782	788	PF00498	0.368
LIG_FHA_2	944	950	PF00498	0.491
LIG_FHA_2	969	975	PF00498	0.575
LIG_IBAR_NPY_1	632	634	PF08397	0.538
LIG_LIR_Apic_2	174	178	PF02991	0.366
LIG_LIR_Apic_2	27	31	PF02991	0.516
LIG_LIR_Apic_2	374	380	PF02991	0.461
LIG_LIR_Apic_2	424	429	PF02991	0.538
LIG_LIR_Apic_2	43	48	PF02991	0.357
LIG_LIR_Apic_2	676	682	PF02991	0.458
LIG_LIR_Apic_2	897	903	PF02991	0.513
LIG_LIR_Gen_1	255	263	PF02991	0.453
LIG_LIR_Gen_1	402	411	PF02991	0.472
LIG_LIR_Gen_1	643	653	PF02991	0.471
LIG_LIR_Gen_1	69	75	PF02991	0.523
LIG_LIR_Gen_1	802	810	PF02991	0.390
LIG_LIR_Gen_1	822	833	PF02991	0.517
LIG_LIR_Gen_1	836	845	PF02991	0.538
LIG_LIR_Gen_1	882	889	PF02991	0.508
LIG_LIR_Gen_1	906	917	PF02991	0.466
LIG_LIR_Nem_3	174	179	PF02991	0.380
LIG_LIR_Nem_3	255	259	PF02991	0.453
LIG_LIR_Nem_3	309	313	PF02991	0.385
LIG_LIR_Nem_3	402	407	PF02991	0.458
LIG_LIR_Nem_3	532	538	PF02991	0.458
LIG_LIR_Nem_3	555	561	PF02991	0.452
LIG_LIR_Nem_3	603	609	PF02991	0.458
LIG_LIR_Nem_3	643	649	PF02991	0.471
LIG_LIR_Nem_3	678	683	PF02991	0.489
LIG_LIR_Nem_3	802	806	PF02991	0.410
LIG_LIR_Nem_3	836	841	PF02991	0.470
LIG_LIR_Nem_3	842	848	PF02991	0.444
LIG_LIR_Nem_3	882	888	PF02991	0.487
LIG_LIR_Nem_3	906	912	PF02991	0.466
LIG_PCNA_yPIPBox_3	808	818	PF02747	0.504
LIG_Pex14_1	172	176	PF04695	0.350
LIG_Pex14_1	193	197	PF04695	0.510
LIG_Pex14_1	426	430	PF04695	0.538
LIG_Pex14_1	534	538	PF04695	0.458
LIG_Pex14_1	81	85	PF04695	0.510
LIG_Pex14_2	205	209	PF04695	0.381
LIG_Pex14_2	67	71	PF04695	0.458
LIG_Pex14_2	806	810	PF04695	0.312
LIG_PTB_Apo_2	200	207	PF02174	0.433
LIG_PTB_Apo_2	832	839	PF02174	0.478
LIG_REV1ctd_RIR_1	203	212	PF16727	0.352
LIG_RPA_C_Insects	911	926	PF08784	0.162
LIG_SH2_CRK	106	110	PF00017	0.449
LIG_SH2_CRK	256	260	PF00017	0.312
LIG_SH2_CRK	373	377	PF00017	0.315
LIG_SH2_CRK	486	490	PF00017	0.361
LIG_SH2_CRK	650	654	PF00017	0.463
LIG_SH2_CRK	909	913	PF00017	0.330
LIG_SH2_GRB2like	337	340	PF00017	0.391
LIG_SH2_GRB2like	341	344	PF00017	0.376
LIG_SH2_GRB2like	404	407	PF00017	0.312
LIG_SH2_GRB2like	49	52	PF00017	0.312
LIG_SH2_NCK_1	373	377	PF00017	0.384
LIG_SH2_NCK_1	634	638	PF00017	0.162
LIG_SH2_NCK_1	702	706	PF00017	0.312
LIG_SH2_NCK_1	866	870	PF00017	0.457
LIG_SH2_SRC	341	344	PF00017	0.423
LIG_SH2_SRC	512	515	PF00017	0.354
LIG_SH2_SRC	648	651	PF00017	0.423
LIG_SH2_STAP1	373	377	PF00017	0.384
LIG_SH2_STAP1	866	870	PF00017	0.423
LIG_SH2_STAP1	909	913	PF00017	0.330
LIG_SH2_STAT3	1006	1009	PF00017	0.559
LIG_SH2_STAT5	175	178	PF00017	0.356
LIG_SH2_STAT5	229	232	PF00017	0.318
LIG_SH2_STAT5	256	259	PF00017	0.276
LIG_SH2_STAT5	314	317	PF00017	0.377
LIG_SH2_STAT5	325	328	PF00017	0.387
LIG_SH2_STAT5	341	344	PF00017	0.224
LIG_SH2_STAT5	373	376	PF00017	0.327
LIG_SH2_STAT5	377	380	PF00017	0.296
LIG_SH2_STAT5	404	407	PF00017	0.312
LIG_SH2_STAT5	41	44	PF00017	0.384
LIG_SH2_STAT5	535	538	PF00017	0.354
LIG_SH2_STAT5	586	589	PF00017	0.457
LIG_SH2_STAT5	610	613	PF00017	0.312
LIG_SH2_STAT5	648	651	PF00017	0.330
LIG_SH2_STAT5	851	854	PF00017	0.370
LIG_SH2_STAT5	945	948	PF00017	0.390
LIG_SH2_STAT5	950	953	PF00017	0.398
LIG_SH3_1	1058	1064	PF00018	0.463
LIG_SH3_1	142	148	PF00018	0.578
LIG_SH3_3	1058	1064	PF00018	0.430
LIG_SH3_3	107	113	PF00018	0.442
LIG_SH3_3	118	124	PF00018	0.586
LIG_SH3_3	142	148	PF00018	0.544
LIG_SH3_3	228	234	PF00018	0.312
LIG_SH3_3	260	266	PF00018	0.322
LIG_SH3_3	281	287	PF00018	0.327
LIG_SH3_3	359	365	PF00018	0.338
LIG_SH3_3	366	372	PF00018	0.320
LIG_SH3_3	660	666	PF00018	0.423
LIG_SH3_3	872	878	PF00018	0.312
LIG_SH3_3	893	899	PF00018	0.368
LIG_SUMO_SIM_anti_2	867	873	PF11976	0.391
LIG_SUMO_SIM_par_1	177	183	PF11976	0.395
LIG_SUMO_SIM_par_1	434	440	PF11976	0.423
LIG_SUMO_SIM_par_1	524	532	PF11976	0.312
LIG_SUMO_SIM_par_1	7	13	PF11976	0.428
LIG_TRAF2_1	938	941	PF00917	0.384
LIG_TRFH_1	634	638	PF08558	0.423
LIG_TYR_ITIM	907	912	PF00017	0.330
LIG_UBA3_1	992	1000	PF00899	0.539
LIG_WRC_WIRS_1	184	189	PF05994	0.431
LIG_WRC_WIRS_1	995	1000	PF05994	0.456
LIG_WW_1	38	41	PF00397	0.261
MOD_CDK_SPK_2	230	235	PF00069	0.423
MOD_CDK_SPxxK_3	120	127	PF00069	0.566
MOD_CK1_1	1024	1030	PF00069	0.494
MOD_CK1_1	1031	1037	PF00069	0.448
MOD_CK1_1	196	202	PF00069	0.295
MOD_CK1_1	395	401	PF00069	0.326
MOD_CK1_1	601	607	PF00069	0.321
MOD_CK1_1	894	900	PF00069	0.393
MOD_CK2_1	1045	1051	PF00069	0.525
MOD_CK2_1	345	351	PF00069	0.393
MOD_CK2_1	380	386	PF00069	0.330
MOD_CK2_1	519	525	PF00069	0.312
MOD_CK2_1	60	66	PF00069	0.312
MOD_CK2_1	738	744	PF00069	0.312
MOD_CK2_1	781	787	PF00069	0.417
MOD_CK2_1	943	949	PF00069	0.459
MOD_CK2_1	968	974	PF00069	0.498
MOD_Cter_Amidation	225	228	PF01082	0.312
MOD_Cter_Amidation	75	78	PF01082	0.330
MOD_Cter_Amidation	861	864	PF01082	0.457
MOD_GlcNHglycan	1033	1036	PF01048	0.397
MOD_GlcNHglycan	1042	1045	PF01048	0.424
MOD_GlcNHglycan	142	145	PF01048	0.734
MOD_GlcNHglycan	246	249	PF01048	0.330
MOD_GlcNHglycan	366	369	PF01048	0.350
MOD_GlcNHglycan	521	524	PF01048	0.343
MOD_GlcNHglycan	687	690	PF01048	0.312
MOD_GSK3_1	1024	1031	PF00069	0.432
MOD_GSK3_1	193	200	PF00069	0.295
MOD_GSK3_1	302	309	PF00069	0.209
MOD_GSK3_1	371	378	PF00069	0.407
MOD_GSK3_1	596	603	PF00069	0.312
MOD_GSK3_1	789	796	PF00069	0.478
MOD_GSK3_1	839	846	PF00069	0.316
MOD_N-GLC_1	1024	1029	PF02516	0.560
MOD_N-GLC_1	405	410	PF02516	0.312
MOD_N-GLC_1	458	463	PF02516	0.423
MOD_N-GLC_1	810	815	PF02516	0.411
MOD_N-GLC_1	967	972	PF02516	0.576
MOD_NEK2_1	565	570	PF00069	0.330
MOD_NEK2_1	60	65	PF00069	0.306
MOD_NEK2_1	600	605	PF00069	0.319
MOD_NEK2_1	685	690	PF00069	0.312
MOD_NEK2_1	732	737	PF00069	0.312
MOD_NEK2_1	780	785	PF00069	0.371
MOD_NEK2_1	810	815	PF00069	0.330
MOD_NEK2_1	85	90	PF00069	0.310
MOD_NEK2_1	907	912	PF00069	0.389
MOD_NEK2_2	287	292	PF00069	0.312
MOD_NEK2_2	372	377	PF00069	0.384
MOD_NEK2_2	666	671	PF00069	0.457
MOD_PIKK_1	1010	1016	PF00454	0.563
MOD_PIKK_1	265	271	PF00454	0.402
MOD_PIKK_1	405	411	PF00454	0.312
MOD_PIKK_1	495	501	PF00454	0.236
MOD_PIKK_1	843	849	PF00454	0.330
MOD_PIKK_1	894	900	PF00454	0.423
MOD_PIKK_1	924	930	PF00454	0.336
MOD_PKA_1	127	133	PF00069	0.480
MOD_PKA_2	1031	1037	PF00069	0.498
MOD_PKA_2	193	199	PF00069	0.295
MOD_PKA_2	244	250	PF00069	0.350
MOD_PKA_2	306	312	PF00069	0.162
MOD_PKA_2	685	691	PF00069	0.312
MOD_PKA_2	76	82	PF00069	0.354
MOD_PKA_2	771	777	PF00069	0.344
MOD_Plk_1	1028	1034	PF00069	0.502
MOD_Plk_1	1045	1051	PF00069	0.345
MOD_Plk_1	254	260	PF00069	0.276
MOD_Plk_1	405	411	PF00069	0.312
MOD_Plk_1	565	571	PF00069	0.312
MOD_Plk_1	601	607	PF00069	0.312
MOD_Plk_1	751	757	PF00069	0.312
MOD_Plk_1	810	816	PF00069	0.366
MOD_Plk_1	843	849	PF00069	0.320
MOD_Plk_1	907	913	PF00069	0.391
MOD_Plk_1	967	973	PF00069	0.498
MOD_Plk_2-3	1045	1051	PF00069	0.564
MOD_Plk_2-3	639	645	PF00069	0.316
MOD_Plk_4	254	260	PF00069	0.276
MOD_Plk_4	292	298	PF00069	0.336
MOD_Plk_4	372	378	PF00069	0.300
MOD_Plk_4	477	483	PF00069	0.457
MOD_Plk_4	582	588	PF00069	0.362
MOD_Plk_4	591	597	PF00069	0.278
MOD_Plk_4	601	607	PF00069	0.160
MOD_Plk_4	695	701	PF00069	0.330
MOD_Plk_4	781	787	PF00069	0.441
MOD_Plk_4	813	819	PF00069	0.354
MOD_Plk_4	891	897	PF00069	0.314
MOD_Plk_4	907	913	PF00069	0.312
MOD_Plk_4	994	1000	PF00069	0.540
MOD_ProDKin_1	120	126	PF00069	0.629
MOD_ProDKin_1	230	236	PF00069	0.312
MOD_ProDKin_1	397	403	PF00069	0.312
MOD_ProDKin_1	87	93	PF00069	0.312
MOD_SUMO_for_1	1072	1075	PF00179	0.653
MOD_SUMO_for_1	318	321	PF00179	0.457
MOD_SUMO_for_1	422	425	PF00179	0.312
MOD_SUMO_rev_2	115	121	PF00179	0.601
MOD_SUMO_rev_2	182	187	PF00179	0.384
MOD_SUMO_rev_2	268	278	PF00179	0.454
MOD_SUMO_rev_2	462	470	PF00179	0.333
MOD_SUMO_rev_2	492	496	PF00179	0.423
TRG_DiLeu_BaEn_1	668	673	PF01217	0.457
TRG_DiLeu_BaEn_1	867	872	PF01217	0.312
TRG_DiLeu_BaEn_2	443	449	PF01217	0.402
TRG_ENDOCYTIC_2	256	259	PF00928	0.303
TRG_ENDOCYTIC_2	337	340	PF00928	0.354
TRG_ENDOCYTIC_2	373	376	PF00928	0.330
TRG_ENDOCYTIC_2	404	407	PF00928	0.314
TRG_ENDOCYTIC_2	486	489	PF00928	0.361
TRG_ENDOCYTIC_2	512	515	PF00928	0.423
TRG_ENDOCYTIC_2	609	612	PF00928	0.314
TRG_ENDOCYTIC_2	650	653	PF00928	0.384
TRG_ENDOCYTIC_2	803	806	PF00928	0.442
TRG_ENDOCYTIC_2	825	828	PF00928	0.330
TRG_ENDOCYTIC_2	865	868	PF00928	0.312
TRG_ENDOCYTIC_2	909	912	PF00928	0.330
TRG_ER_diArg_1	193	195	PF00400	0.312
TRG_ER_diArg_1	217	219	PF00400	0.423
TRG_ER_diArg_1	863	865	PF00400	0.386
TRG_NLS_Bipartite_1	127	143	PF00514	0.523
TRG_NLS_MonoExtC_3	543	549	PF00514	0.162
TRG_NLS_MonoExtC_3	933	938	PF00514	0.330
TRG_NLS_MonoExtN_4	137	143	PF00514	0.616
TRG_NLS_MonoExtN_4	931	938	PF00514	0.330
TRG_Pf-PMV_PEXEL_1	1040	1045	PF00026	0.559
TRG_Pf-PMV_PEXEL_1	962	966	PF00026	0.285

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0Z6	Leptomonas seymouri	78%	100%
A0A0S4J826	Bodo saltans	62%	99%
A0A1X0NNK0	Trypanosomatidae	65%	100%
A0A3Q8II14	Leishmania donovani	94%	100%
A0A422NLI7	Trypanosoma rangeli	65%	100%
A0B7B7	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	30%	100%
A1RTX9	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	28%	100%
A3DKS1	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	29%	100%
A3MU00	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	29%	100%
A4FYA3	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	29%	100%
A4H796	Leishmania braziliensis	92%	100%
A4HVN8	Leishmania infantum	94%	100%
A4WHK6	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	28%	100%
A4YE96	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	26%	100%
A4YI28	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	28%	100%
A6USJ5	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	28%	100%
A6UTK3	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)	28%	100%
A6VK04	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	28%	100%
A8A8T2	Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)	29%	100%
B1YAS9	Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta)	29%	100%
B6YST9	Thermococcus onnurineus (strain NA1)	30%	100%
F4I116	Arabidopsis thaliana	41%	99%
O27552	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	27%	100%
O30250	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	31%	100%
O33768	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	29%	100%
O58698	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	29%	100%
P10857	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	37%	96%
P26637	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	99%
P58176	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	24%	100%
Q09996	Caenorhabditis elegans	44%	91%
Q10490	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	97%
Q12WA2	Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)	29%	100%
Q46AW0	Methanosarcina barkeri (strain Fusaro / DSM 804)	29%	100%
Q4J8J7	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	29%	100%
Q4JBP0	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	25%	100%
Q4QG44	Leishmania major	95%	100%
Q54N83	Dictyostelium discoideum	42%	100%
Q58050	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	29%	100%
Q5R614	Pongo abelii	42%	91%
Q6LZD2	Methanococcus maripaludis (strain S2 / LL)	29%	100%
Q8BMJ2	Mus musculus	41%	91%
Q8NKR7	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	29%	100%
Q8Q054	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	30%	100%
Q8TQD3	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	29%	100%
Q8TVM4	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	30%	100%
Q8U2E6	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	28%	100%
Q8ZXT6	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	29%	100%
Q970Z6	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	29%	100%
Q974N4	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	27%	100%
Q97AN8	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	27%	100%
Q9HK31	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	29%	100%
Q9P2J5	Homo sapiens	41%	91%
Q9V0B9	Pyrococcus abyssi (strain GE5 / Orsay)	28%	100%
Q9YD97	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	33%	100%
V5B774	Trypanosoma cruzi	66%	100%