Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9APB0_LEIMU

TriTrypDb:

LmxM.13.0860

Length:

347

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9APB0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9APB0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	281	285	PF00656	0.670
CLV_NRD_NRD_1	160	162	PF00675	0.644
CLV_NRD_NRD_1	183	185	PF00675	0.583
CLV_NRD_NRD_1	246	248	PF00675	0.680
CLV_NRD_NRD_1	310	312	PF00675	0.399
CLV_NRD_NRD_1	56	58	PF00675	0.768
CLV_PCSK_FUR_1	54	58	PF00082	0.657
CLV_PCSK_KEX2_1	124	126	PF00082	0.590
CLV_PCSK_KEX2_1	143	145	PF00082	0.662
CLV_PCSK_KEX2_1	160	162	PF00082	0.711
CLV_PCSK_KEX2_1	183	185	PF00082	0.550
CLV_PCSK_KEX2_1	250	252	PF00082	0.751
CLV_PCSK_KEX2_1	310	312	PF00082	0.557
CLV_PCSK_KEX2_1	315	317	PF00082	0.588
CLV_PCSK_KEX2_1	56	58	PF00082	0.768
CLV_PCSK_PC1ET2_1	124	126	PF00082	0.587
CLV_PCSK_PC1ET2_1	143	145	PF00082	0.600
CLV_PCSK_PC1ET2_1	250	252	PF00082	0.751
CLV_PCSK_PC1ET2_1	315	317	PF00082	0.595
CLV_PCSK_PC7_1	311	317	PF00082	0.545
CLV_PCSK_SKI1_1	144	148	PF00082	0.633
CLV_PCSK_SKI1_1	251	255	PF00082	0.744
DEG_SCF_FBW7_1	22	27	PF00400	0.489
DEG_SPOP_SBC_1	9	13	PF00917	0.524
DOC_CKS1_1	37	42	PF01111	0.595
DOC_PP4_FxxP_1	127	130	PF00568	0.684
DOC_PP4_FxxP_1	134	137	PF00568	0.591
DOC_PP4_FxxP_1	270	273	PF00568	0.489
DOC_USP7_MATH_1	2	6	PF00917	0.661
DOC_USP7_MATH_1	226	230	PF00917	0.648
DOC_USP7_MATH_1	262	266	PF00917	0.680
DOC_USP7_MATH_1	328	332	PF00917	0.605
DOC_USP7_MATH_1	86	90	PF00917	0.487
DOC_USP7_MATH_1	9	13	PF00917	0.606
DOC_USP7_UBL2_3	120	124	PF12436	0.586
DOC_WW_Pin1_4	20	25	PF00397	0.731
DOC_WW_Pin1_4	233	238	PF00397	0.595
DOC_WW_Pin1_4	258	263	PF00397	0.659
DOC_WW_Pin1_4	36	41	PF00397	0.528
DOC_WW_Pin1_4	47	52	PF00397	0.641
LIG_AP2alpha_2	99	101	PF02296	0.615
LIG_BIR_II_1	1	5	PF00653	0.609
LIG_BIR_III_1	1	5	PF00653	0.595
LIG_BIR_III_3	1	5	PF00653	0.595
LIG_BRCT_BRCA1_1	11	15	PF00533	0.773
LIG_CSL_BTD_1	138	141	PF09270	0.613
LIG_FHA_1	25	31	PF00498	0.695
LIG_FHA_1	259	265	PF00498	0.692
LIG_FHA_2	205	211	PF00498	0.580
LIG_FHA_2	21	27	PF00498	0.643
LIG_FHA_2	299	305	PF00498	0.525
LIG_Integrin_isoDGR_2	245	247	PF01839	0.686
LIG_LIR_Apic_2	169	175	PF02991	0.672
LIG_LIR_Apic_2	35	40	PF02991	0.585
LIG_LIR_Nem_3	89	95	PF02991	0.563
LIG_SH2_STAT5	115	118	PF00017	0.577
LIG_SH3_3	105	111	PF00018	0.602
LIG_SH3_3	135	141	PF00018	0.565
LIG_SH3_3	142	148	PF00018	0.602
LIG_SH3_3	197	203	PF00018	0.603
LIG_SH3_3	270	276	PF00018	0.686
LIG_TRAF2_1	148	151	PF00917	0.558
LIG_TRAF2_1	207	210	PF00917	0.735
MOD_CDK_SPxxK_3	47	54	PF00069	0.611
MOD_CK1_1	16	22	PF00069	0.514
MOD_CK2_1	2	8	PF00069	0.673
MOD_CK2_1	20	26	PF00069	0.485
MOD_CK2_1	204	210	PF00069	0.581
MOD_CK2_1	298	304	PF00069	0.538
MOD_Cter_Amidation	122	125	PF01082	0.576
MOD_Cter_Amidation	245	248	PF01082	0.641
MOD_GlcNHglycan	15	18	PF01048	0.587
MOD_GlcNHglycan	264	267	PF01048	0.750
MOD_GlcNHglycan	4	7	PF01048	0.726
MOD_GlcNHglycan	79	82	PF01048	0.644
MOD_GlcNHglycan	88	91	PF01048	0.567
MOD_GSK3_1	20	27	PF00069	0.585
MOD_GSK3_1	214	221	PF00069	0.720
MOD_GSK3_1	258	265	PF00069	0.738
MOD_GSK3_1	32	39	PF00069	0.564
MOD_GSK3_1	42	49	PF00069	0.692
MOD_GSK3_1	77	84	PF00069	0.617
MOD_GSK3_1	9	16	PF00069	0.788
MOD_N-GLC_1	166	171	PF02516	0.676
MOD_N-GLC_1	282	287	PF02516	0.670
MOD_NEK2_1	15	20	PF00069	0.782
MOD_NEK2_1	32	37	PF00069	0.504
MOD_NEK2_1	320	325	PF00069	0.600
MOD_PIKK_1	282	288	PF00454	0.673
MOD_PIKK_1	32	38	PF00454	0.589
MOD_PKA_2	298	304	PF00069	0.532
MOD_Plk_1	204	210	PF00069	0.555
MOD_Plk_1	282	288	PF00069	0.673
MOD_Plk_1	42	48	PF00069	0.750
MOD_Plk_4	209	215	PF00069	0.666
MOD_ProDKin_1	20	26	PF00069	0.731
MOD_ProDKin_1	233	239	PF00069	0.596
MOD_ProDKin_1	258	264	PF00069	0.661
MOD_ProDKin_1	36	42	PF00069	0.531
MOD_ProDKin_1	47	53	PF00069	0.646
TRG_ER_diArg_1	160	163	PF00400	0.639
TRG_ER_diArg_1	54	57	PF00400	0.736
TRG_NLS_MonoExtC_3	246	251	PF00514	0.534
TRG_Pf-PMV_PEXEL_1	56	61	PF00026	0.496

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I155	Leptomonas seymouri	49%	100%
A0A3Q8I8I3	Leishmania donovani	88%	89%
A4H774	Leishmania braziliensis	72%	95%
A4HVL4	Leishmania infantum	88%	89%
Q4QG68	Leishmania major	89%	100%