LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9APA8_LEIMU
TriTrypDb:
LmxM.13.0840
Length:
1142

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9APA8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9APA8

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1079 1083 PF00656 0.733
CLV_C14_Caspase3-7 17 21 PF00656 0.672
CLV_C14_Caspase3-7 220 224 PF00656 0.755
CLV_C14_Caspase3-7 229 233 PF00656 0.658
CLV_C14_Caspase3-7 242 246 PF00656 0.515
CLV_C14_Caspase3-7 387 391 PF00656 0.673
CLV_C14_Caspase3-7 500 504 PF00656 0.564
CLV_C14_Caspase3-7 676 680 PF00656 0.690
CLV_C14_Caspase3-7 917 921 PF00656 0.682
CLV_MEL_PAP_1 987 993 PF00089 0.552
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S7WSK8 Leishmania donovani 76% 98%
A4H772 Leishmania braziliensis 50% 100%
A4HVL2 Leishmania infantum 76% 98%
Q4QG70 Leishmania major 74% 97%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS