Putative RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA helicase, putative

Species:

Leishmania mexicana

UniProt:

E9AP74_LEIMU

TriTrypDb:

LmxM.13.0500

Length:

1985

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AP74

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0010467	gene expression	4	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0046483	heterocycle metabolic process	3	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016787	hydrolase activity	2	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1048	1052	PF00656	0.443
CLV_C14_Caspase3-7	152	156	PF00656	0.594
CLV_C14_Caspase3-7	1568	1572	PF00656	0.335
CLV_C14_Caspase3-7	1624	1628	PF00656	0.533
CLV_C14_Caspase3-7	1743	1747	PF00656	0.443
CLV_C14_Caspase3-7	812	816	PF00656	0.438
CLV_NRD_NRD_1	1064	1066	PF00675	0.243
CLV_NRD_NRD_1	1387	1389	PF00675	0.336
CLV_NRD_NRD_1	1535	1537	PF00675	0.327
CLV_NRD_NRD_1	1583	1585	PF00675	0.307
CLV_NRD_NRD_1	203	205	PF00675	0.530
CLV_NRD_NRD_1	354	356	PF00675	0.244
CLV_NRD_NRD_1	394	396	PF00675	0.243
CLV_NRD_NRD_1	529	531	PF00675	0.345
CLV_NRD_NRD_1	59	61	PF00675	0.417
CLV_NRD_NRD_1	744	746	PF00675	0.411
CLV_NRD_NRD_1	807	809	PF00675	0.257
CLV_PCSK_KEX2_1	1387	1389	PF00082	0.336
CLV_PCSK_KEX2_1	1583	1585	PF00082	0.307
CLV_PCSK_KEX2_1	1898	1900	PF00082	0.209
CLV_PCSK_KEX2_1	1929	1931	PF00082	0.243
CLV_PCSK_KEX2_1	203	205	PF00082	0.453
CLV_PCSK_KEX2_1	219	221	PF00082	0.291
CLV_PCSK_KEX2_1	258	260	PF00082	0.521
CLV_PCSK_KEX2_1	354	356	PF00082	0.243
CLV_PCSK_KEX2_1	374	376	PF00082	0.112
CLV_PCSK_KEX2_1	498	500	PF00082	0.546
CLV_PCSK_KEX2_1	638	640	PF00082	0.373
CLV_PCSK_KEX2_1	807	809	PF00082	0.254
CLV_PCSK_PC1ET2_1	1898	1900	PF00082	0.209
CLV_PCSK_PC1ET2_1	1929	1931	PF00082	0.243
CLV_PCSK_PC1ET2_1	219	221	PF00082	0.403
CLV_PCSK_PC1ET2_1	258	260	PF00082	0.557
CLV_PCSK_PC1ET2_1	374	376	PF00082	0.254
CLV_PCSK_PC1ET2_1	498	500	PF00082	0.574
CLV_PCSK_PC1ET2_1	638	640	PF00082	0.392
CLV_PCSK_SKI1_1	1017	1021	PF00082	0.268
CLV_PCSK_SKI1_1	1217	1221	PF00082	0.292
CLV_PCSK_SKI1_1	1359	1363	PF00082	0.456
CLV_PCSK_SKI1_1	137	141	PF00082	0.313
CLV_PCSK_SKI1_1	1536	1540	PF00082	0.330
CLV_PCSK_SKI1_1	154	158	PF00082	0.497
CLV_PCSK_SKI1_1	1600	1604	PF00082	0.419
CLV_PCSK_SKI1_1	1611	1615	PF00082	0.324
CLV_PCSK_SKI1_1	166	170	PF00082	0.501
CLV_PCSK_SKI1_1	171	175	PF00082	0.446
CLV_PCSK_SKI1_1	1718	1722	PF00082	0.261
CLV_PCSK_SKI1_1	1770	1774	PF00082	0.321
CLV_PCSK_SKI1_1	1797	1801	PF00082	0.329
CLV_PCSK_SKI1_1	331	335	PF00082	0.243
CLV_PCSK_SKI1_1	364	368	PF00082	0.243
CLV_PCSK_SKI1_1	88	92	PF00082	0.384
CLV_PCSK_SKI1_1	909	913	PF00082	0.243
CLV_Separin_Metazoa	1672	1676	PF03568	0.529
CLV_Separin_Metazoa	401	405	PF03568	0.340
DEG_APCC_DBOX_1	442	450	PF00400	0.504
DEG_APCC_DBOX_1	638	646	PF00400	0.361
DEG_SPOP_SBC_1	1466	1470	PF00917	0.443
DOC_CKS1_1	384	389	PF01111	0.443
DOC_CYCLIN_RxL_1	1120	1128	PF00134	0.483
DOC_CYCLIN_RxL_1	1698	1709	PF00134	0.529
DOC_CYCLIN_RxL_1	1848	1859	PF00134	0.529
DOC_CYCLIN_RxL_1	85	95	PF00134	0.469
DOC_CYCLIN_RxL_1	906	915	PF00134	0.443
DOC_CYCLIN_yCln2_LP_2	1078	1084	PF00134	0.454
DOC_CYCLIN_yCln2_LP_2	1301	1307	PF00134	0.487
DOC_CYCLIN_yCln2_LP_2	1539	1545	PF00134	0.321
DOC_MAPK_DCC_7	1123	1132	PF00069	0.443
DOC_MAPK_gen_1	106	113	PF00069	0.459
DOC_MAPK_gen_1	1212	1221	PF00069	0.500
DOC_MAPK_gen_1	135	143	PF00069	0.319
DOC_MAPK_gen_1	1387	1397	PF00069	0.325
DOC_MAPK_gen_1	237	244	PF00069	0.527
DOC_MAPK_gen_1	515	525	PF00069	0.388
DOC_MAPK_gen_1	530	536	PF00069	0.305
DOC_MAPK_gen_1	60	68	PF00069	0.380
DOC_MAPK_gen_1	638	645	PF00069	0.382
DOC_MAPK_gen_1	906	916	PF00069	0.504
DOC_MAPK_HePTP_8	1371	1383	PF00069	0.382
DOC_MAPK_MEF2A_6	1002	1010	PF00069	0.516
DOC_MAPK_MEF2A_6	1017	1026	PF00069	0.418
DOC_MAPK_MEF2A_6	1283	1291	PF00069	0.504
DOC_MAPK_MEF2A_6	1340	1348	PF00069	0.362
DOC_MAPK_MEF2A_6	135	143	PF00069	0.319
DOC_MAPK_MEF2A_6	1374	1383	PF00069	0.375
DOC_MAPK_MEF2A_6	1851	1860	PF00069	0.484
DOC_MAPK_MEF2A_6	237	246	PF00069	0.513
DOC_MAPK_MEF2A_6	308	317	PF00069	0.454
DOC_MAPK_MEF2A_6	518	527	PF00069	0.386
DOC_MAPK_MEF2A_6	638	647	PF00069	0.360
DOC_MAPK_RevD_3	382	396	PF00069	0.443
DOC_PP1_RVXF_1	1267	1274	PF00149	0.443
DOC_PP1_RVXF_1	1293	1300	PF00149	0.443
DOC_PP1_RVXF_1	1890	1896	PF00149	0.529
DOC_PP1_RVXF_1	1941	1947	PF00149	0.521
DOC_PP1_RVXF_1	332	338	PF00149	0.454
DOC_PP1_SILK_1	1017	1022	PF00149	0.529
DOC_PP2B_LxvP_1	1078	1081	PF13499	0.454
DOC_PP2B_LxvP_1	1112	1115	PF13499	0.375
DOC_PP2B_LxvP_1	1169	1172	PF13499	0.443
DOC_PP2B_LxvP_1	1301	1304	PF13499	0.487
DOC_PP2B_LxvP_1	1703	1706	PF13499	0.484
DOC_PP2B_LxvP_1	1790	1793	PF13499	0.454
DOC_PP2B_LxvP_1	1831	1834	PF13499	0.529
DOC_PP2B_LxvP_1	1981	1984	PF13499	0.239
DOC_PP2B_PxIxI_1	1853	1859	PF00149	0.454
DOC_PP4_FxxP_1	1979	1982	PF00568	0.411
DOC_PP4_FxxP_1	337	340	PF00568	0.443
DOC_PP4_FxxP_1	941	944	PF00568	0.454
DOC_USP7_MATH_1	1115	1119	PF00917	0.455
DOC_USP7_MATH_1	1172	1176	PF00917	0.443
DOC_USP7_MATH_1	1544	1548	PF00917	0.320
DOC_USP7_MATH_1	156	160	PF00917	0.641
DOC_USP7_MATH_1	1666	1670	PF00917	0.487
DOC_USP7_MATH_1	2	6	PF00917	0.498
DOC_USP7_MATH_1	689	693	PF00917	0.337
DOC_USP7_UBL2_3	1204	1208	PF12436	0.443
DOC_WD40_RPTOR_TOS_1	912	917	PF00400	0.529
DOC_WW_Pin1_4	1069	1074	PF00397	0.529
DOC_WW_Pin1_4	1125	1130	PF00397	0.439
DOC_WW_Pin1_4	1230	1235	PF00397	0.461
DOC_WW_Pin1_4	1245	1250	PF00397	0.401
DOC_WW_Pin1_4	1372	1377	PF00397	0.370
DOC_WW_Pin1_4	1595	1600	PF00397	0.355
DOC_WW_Pin1_4	1711	1716	PF00397	0.443
DOC_WW_Pin1_4	1951	1956	PF00397	0.493
DOC_WW_Pin1_4	383	388	PF00397	0.443
DOC_WW_Pin1_4	39	44	PF00397	0.492
LIG_14-3-3_CanoR_1	1092	1099	PF00244	0.443
LIG_14-3-3_CanoR_1	1262	1272	PF00244	0.454
LIG_14-3-3_CanoR_1	1359	1364	PF00244	0.478
LIG_14-3-3_CanoR_1	1391	1398	PF00244	0.324
LIG_14-3-3_CanoR_1	1729	1733	PF00244	0.382
LIG_14-3-3_CanoR_1	1770	1775	PF00244	0.438
LIG_14-3-3_CanoR_1	1892	1896	PF00244	0.454
LIG_14-3-3_CanoR_1	1933	1942	PF00244	0.487
LIG_14-3-3_CanoR_1	530	535	PF00244	0.347
LIG_14-3-3_CanoR_1	595	602	PF00244	0.347
LIG_14-3-3_CanoR_1	60	65	PF00244	0.421
LIG_14-3-3_CanoR_1	754	758	PF00244	0.451
LIG_14-3-3_CanoR_1	787	796	PF00244	0.443
LIG_14-3-3_CanoR_1	885	889	PF00244	0.548
LIG_14-3-3_CanoR_1	954	962	PF00244	0.516
LIG_14-3-3_CanoR_1	96	103	PF00244	0.547
LIG_Actin_WH2_2	1921	1937	PF00022	0.529
LIG_Actin_WH2_2	737	753	PF00022	0.434
LIG_AP2alpha_2	1541	1543	PF02296	0.337
LIG_APCC_ABBA_1	1091	1096	PF00400	0.468
LIG_APCC_ABBA_1	1270	1275	PF00400	0.443
LIG_APCC_ABBA_1	799	804	PF00400	0.529
LIG_APCC_ABBAyCdc20_2	1269	1275	PF00400	0.443
LIG_BIR_II_1	1	5	PF00653	0.279
LIG_BIR_III_2	1231	1235	PF00653	0.529
LIG_BIR_III_2	1632	1636	PF00653	0.492
LIG_BRCT_BRCA1_1	1039	1043	PF00533	0.478
LIG_BRCT_BRCA1_1	320	324	PF00533	0.529
LIG_CaM_IQ_9	367	383	PF13499	0.443
LIG_Clathr_ClatBox_1	1270	1274	PF01394	0.443
LIG_Clathr_ClatBox_1	1855	1859	PF01394	0.529
LIG_Clathr_ClatBox_1	408	412	PF01394	0.443
LIG_Clathr_ClatBox_1	911	915	PF01394	0.454
LIG_deltaCOP1_diTrp_1	1250	1259	PF00928	0.443
LIG_deltaCOP1_diTrp_1	1327	1335	PF00928	0.351
LIG_deltaCOP1_diTrp_1	1945	1950	PF00928	0.443
LIG_deltaCOP1_diTrp_1	268	274	PF00928	0.370
LIG_DLG_GKlike_1	1587	1594	PF00625	0.482
LIG_DLG_GKlike_1	60	67	PF00625	0.416
LIG_FHA_1	10	16	PF00498	0.516
LIG_FHA_1	1014	1020	PF00498	0.449
LIG_FHA_1	1070	1076	PF00498	0.529
LIG_FHA_1	1104	1110	PF00498	0.461
LIG_FHA_1	1119	1125	PF00498	0.320
LIG_FHA_1	1231	1237	PF00498	0.468
LIG_FHA_1	1343	1349	PF00498	0.493
LIG_FHA_1	1375	1381	PF00498	0.487
LIG_FHA_1	1420	1426	PF00498	0.433
LIG_FHA_1	1457	1463	PF00498	0.449
LIG_FHA_1	1466	1472	PF00498	0.440
LIG_FHA_1	1501	1507	PF00498	0.443
LIG_FHA_1	1517	1523	PF00498	0.398
LIG_FHA_1	1601	1607	PF00498	0.333
LIG_FHA_1	1654	1660	PF00498	0.507
LIG_FHA_1	1733	1739	PF00498	0.529
LIG_FHA_1	1881	1887	PF00498	0.461
LIG_FHA_1	1920	1926	PF00498	0.454
LIG_FHA_1	1937	1943	PF00498	0.454
LIG_FHA_1	1956	1962	PF00498	0.488
LIG_FHA_1	223	229	PF00498	0.517
LIG_FHA_1	378	384	PF00498	0.443
LIG_FHA_1	531	537	PF00498	0.348
LIG_FHA_1	611	617	PF00498	0.365
LIG_FHA_1	624	630	PF00498	0.368
LIG_FHA_1	734	740	PF00498	0.490
LIG_FHA_1	775	781	PF00498	0.439
LIG_FHA_1	85	91	PF00498	0.341
LIG_FHA_1	874	880	PF00498	0.513
LIG_FHA_1	888	894	PF00498	0.504
LIG_FHA_1	956	962	PF00498	0.443
LIG_FHA_2	1062	1068	PF00498	0.508
LIG_FHA_2	1245	1251	PF00498	0.443
LIG_FHA_2	1449	1455	PF00498	0.454
LIG_FHA_2	147	153	PF00498	0.395
LIG_FHA_2	1566	1572	PF00498	0.358
LIG_FHA_2	1873	1879	PF00498	0.389
LIG_FHA_2	284	290	PF00498	0.548
LIG_FHA_2	371	377	PF00498	0.443
LIG_FHA_2	383	389	PF00498	0.443
LIG_FHA_2	594	600	PF00498	0.361
LIG_FHA_2	810	816	PF00498	0.461
LIG_FHA_2	96	102	PF00498	0.413
LIG_FHA_2	977	983	PF00498	0.475
LIG_FXI_DFP_1	1497	1501	PF00024	0.284
LIG_GBD_Chelix_1	459	467	PF00786	0.389
LIG_Integrin_RGD_1	44	46	PF01839	0.547
LIG_LIR_Apic_2	1978	1982	PF02991	0.559
LIG_LIR_Apic_2	268	272	PF02991	0.470
LIG_LIR_Apic_2	940	944	PF02991	0.468
LIG_LIR_Gen_1	1041	1051	PF02991	0.443
LIG_LIR_Gen_1	1137	1146	PF02991	0.349
LIG_LIR_Gen_1	123	134	PF02991	0.346
LIG_LIR_Gen_1	1327	1337	PF02991	0.337
LIG_LIR_Gen_1	1367	1376	PF02991	0.489
LIG_LIR_Gen_1	138	147	PF02991	0.297
LIG_LIR_Gen_1	1407	1418	PF02991	0.371
LIG_LIR_Gen_1	1494	1505	PF02991	0.484
LIG_LIR_Gen_1	1577	1586	PF02991	0.306
LIG_LIR_Gen_1	1681	1688	PF02991	0.444
LIG_LIR_Gen_1	1911	1921	PF02991	0.443
LIG_LIR_Gen_1	1974	1984	PF02991	0.548
LIG_LIR_Gen_1	604	610	PF02991	0.353
LIG_LIR_Gen_1	678	688	PF02991	0.455
LIG_LIR_Gen_1	722	730	PF02991	0.318
LIG_LIR_Gen_1	752	762	PF02991	0.384
LIG_LIR_Gen_1	76	86	PF02991	0.339
LIG_LIR_Gen_1	795	802	PF02991	0.511
LIG_LIR_Gen_1	831	837	PF02991	0.445
LIG_LIR_Gen_1	923	930	PF02991	0.446
LIG_LIR_Gen_1	959	970	PF02991	0.529
LIG_LIR_Nem_3	1001	1006	PF02991	0.457
LIG_LIR_Nem_3	1040	1046	PF02991	0.445
LIG_LIR_Nem_3	1137	1142	PF02991	0.225
LIG_LIR_Nem_3	123	129	PF02991	0.347
LIG_LIR_Nem_3	1250	1255	PF02991	0.443
LIG_LIR_Nem_3	1321	1326	PF02991	0.354
LIG_LIR_Nem_3	1327	1333	PF02991	0.321
LIG_LIR_Nem_3	1367	1371	PF02991	0.520
LIG_LIR_Nem_3	138	143	PF02991	0.286
LIG_LIR_Nem_3	145	150	PF02991	0.361
LIG_LIR_Nem_3	1494	1500	PF02991	0.443
LIG_LIR_Nem_3	1577	1581	PF02991	0.312
LIG_LIR_Nem_3	1590	1594	PF02991	0.344
LIG_LIR_Nem_3	1648	1652	PF02991	0.442
LIG_LIR_Nem_3	1681	1686	PF02991	0.444
LIG_LIR_Nem_3	1910	1916	PF02991	0.444
LIG_LIR_Nem_3	1947	1953	PF02991	0.454
LIG_LIR_Nem_3	1974	1980	PF02991	0.488
LIG_LIR_Nem_3	330	336	PF02991	0.445
LIG_LIR_Nem_3	388	393	PF02991	0.443
LIG_LIR_Nem_3	477	481	PF02991	0.382
LIG_LIR_Nem_3	484	490	PF02991	0.443
LIG_LIR_Nem_3	604	609	PF02991	0.336
LIG_LIR_Nem_3	678	683	PF02991	0.451
LIG_LIR_Nem_3	718	723	PF02991	0.334
LIG_LIR_Nem_3	724	730	PF02991	0.334
LIG_LIR_Nem_3	752	758	PF02991	0.405
LIG_LIR_Nem_3	76	82	PF02991	0.344
LIG_LIR_Nem_3	760	765	PF02991	0.353
LIG_LIR_Nem_3	790	796	PF02991	0.504
LIG_LIR_Nem_3	831	835	PF02991	0.445
LIG_LIR_Nem_3	923	928	PF02991	0.446
LIG_LIR_Nem_3	959	965	PF02991	0.504
LIG_NRBOX	1672	1678	PF00104	0.491
LIG_NRBOX	63	69	PF00104	0.474
LIG_PCNA_PIPBox_1	695	704	PF02747	0.391
LIG_PCNA_yPIPBox_3	1251	1265	PF02747	0.500
LIG_PCNA_yPIPBox_3	872	885	PF02747	0.504
LIG_Pex14_1	1473	1477	PF04695	0.426
LIG_Pex14_1	1578	1582	PF04695	0.315
LIG_Pex14_2	1157	1161	PF04695	0.468
LIG_Pex14_2	1534	1538	PF04695	0.326
LIG_Pex14_2	218	222	PF04695	0.511
LIG_Pex14_2	288	292	PF04695	0.443
LIG_Pex14_2	333	337	PF04695	0.443
LIG_Pex14_2	579	583	PF04695	0.356
LIG_PTB_Apo_2	1585	1592	PF02174	0.343
LIG_PTB_Apo_2	756	763	PF02174	0.467
LIG_PTB_Phospho_1	1585	1591	PF10480	0.353
LIG_REV1ctd_RIR_1	599	607	PF16727	0.449
LIG_SH2_CRK	1139	1143	PF00017	0.190
LIG_SH2_CRK	126	130	PF00017	0.359
LIG_SH2_CRK	1368	1372	PF00017	0.430
LIG_SH2_CRK	1640	1644	PF00017	0.353
LIG_SH2_CRK	1766	1770	PF00017	0.454
LIG_SH2_CRK	1977	1981	PF00017	0.548
LIG_SH2_CRK	205	209	PF00017	0.407
LIG_SH2_CRK	478	482	PF00017	0.379
LIG_SH2_CRK	555	559	PF00017	0.567
LIG_SH2_CRK	755	759	PF00017	0.517
LIG_SH2_CRK	925	929	PF00017	0.529
LIG_SH2_GRB2like	79	82	PF00017	0.426
LIG_SH2_GRB2like	882	885	PF00017	0.548
LIG_SH2_NCK_1	755	759	PF00017	0.346
LIG_SH2_NCK_1	796	800	PF00017	0.529
LIG_SH2_PTP2	1199	1202	PF00017	0.443
LIG_SH2_SRC	510	513	PF00017	0.473
LIG_SH2_STAP1	1086	1090	PF00017	0.451
LIG_SH2_STAP1	1094	1098	PF00017	0.433
LIG_SH2_STAP1	1105	1109	PF00017	0.392
LIG_SH2_STAP1	1421	1425	PF00017	0.498
LIG_SH2_STAP1	1884	1888	PF00017	0.468
LIG_SH2_STAP1	1977	1981	PF00017	0.484
LIG_SH2_STAP1	510	514	PF00017	0.419
LIG_SH2_STAP1	723	727	PF00017	0.320
LIG_SH2_STAT3	56	59	PF00017	0.522
LIG_SH2_STAT3	725	728	PF00017	0.318
LIG_SH2_STAT3	899	902	PF00017	0.454
LIG_SH2_STAT5	1105	1108	PF00017	0.504
LIG_SH2_STAT5	1158	1161	PF00017	0.493
LIG_SH2_STAT5	1199	1202	PF00017	0.443
LIG_SH2_STAT5	1264	1267	PF00017	0.443
LIG_SH2_STAT5	1296	1299	PF00017	0.454
LIG_SH2_STAT5	1356	1359	PF00017	0.438
LIG_SH2_STAT5	1421	1424	PF00017	0.410
LIG_SH2_STAT5	1429	1432	PF00017	0.416
LIG_SH2_STAT5	1497	1500	PF00017	0.437
LIG_SH2_STAT5	1575	1578	PF00017	0.319
LIG_SH2_STAT5	1580	1583	PF00017	0.311
LIG_SH2_STAT5	1640	1643	PF00017	0.323
LIG_SH2_STAT5	1651	1654	PF00017	0.414
LIG_SH2_STAT5	1737	1740	PF00017	0.455
LIG_SH2_STAT5	1964	1967	PF00017	0.450
LIG_SH2_STAT5	1970	1973	PF00017	0.444
LIG_SH2_STAT5	539	542	PF00017	0.431
LIG_SH2_STAT5	606	609	PF00017	0.401
LIG_SH2_STAT5	723	726	PF00017	0.320
LIG_SH2_STAT5	79	82	PF00017	0.341
LIG_SH2_STAT5	793	796	PF00017	0.443
LIG_SH2_STAT5	882	885	PF00017	0.443
LIG_SH2_STAT5	899	902	PF00017	0.443
LIG_SH2_STAT5	925	928	PF00017	0.529
LIG_SH3_1	1123	1129	PF00018	0.387
LIG_SH3_2	1126	1131	PF14604	0.389
LIG_SH3_3	1078	1084	PF00018	0.454
LIG_SH3_3	1123	1129	PF00018	0.387
LIG_SH3_3	1311	1317	PF00018	0.489
LIG_SH3_3	1373	1379	PF00018	0.352
LIG_SH3_3	1472	1478	PF00018	0.443
LIG_SH3_3	1495	1501	PF00018	0.454
LIG_SH3_3	1897	1903	PF00018	0.443
LIG_SH3_3	297	303	PF00018	0.454
LIG_SH3_3	37	43	PF00018	0.504
LIG_SH3_3	381	387	PF00018	0.443
LIG_SH3_3	470	476	PF00018	0.409
LIG_SH3_3	617	623	PF00018	0.325
LIG_SH3_5	1733	1737	PF00018	0.443
LIG_Sin3_3	1723	1730	PF02671	0.340
LIG_SUMO_SIM_anti_2	115	123	PF11976	0.473
LIG_SUMO_SIM_anti_2	644	649	PF11976	0.334
LIG_SUMO_SIM_par_1	1224	1229	PF11976	0.443
LIG_SUMO_SIM_par_1	641	646	PF11976	0.401
LIG_TRAF2_1	1869	1872	PF00917	0.534
LIG_TRAF2_1	249	252	PF00917	0.589
LIG_TRAF2_1	398	401	PF00917	0.504
LIG_TRAF2_1	509	512	PF00917	0.476
LIG_TRFH_1	1979	1983	PF08558	0.234
LIG_TYR_ITIM	1638	1643	PF00017	0.389
LIG_TYR_ITIM	508	513	PF00017	0.389
LIG_TYR_ITIM	753	758	PF00017	0.402
LIG_TYR_ITIM	794	799	PF00017	0.504
LIG_UBA3_1	117	124	PF00899	0.428
LIG_UBA3_1	1789	1797	PF00899	0.529
LIG_UBA3_1	1799	1805	PF00899	0.529
LIG_UBA3_1	974	981	PF00899	0.529
LIG_WW_3	247	251	PF00397	0.593
MOD_CDC14_SPxK_1	1128	1131	PF00782	0.456
MOD_CDK_SPK_2	1595	1600	PF00069	0.371
MOD_CDK_SPK_2	39	44	PF00069	0.492
MOD_CDK_SPxK_1	1125	1131	PF00069	0.465
MOD_CDK_SPxK_1	1245	1251	PF00069	0.443
MOD_CDK_SPxK_1	383	389	PF00069	0.443
MOD_CDK_SPxxK_3	1711	1718	PF00069	0.443
MOD_CK1_1	1037	1043	PF00069	0.499
MOD_CK1_1	1118	1124	PF00069	0.463
MOD_CK1_1	1175	1181	PF00069	0.443
MOD_CK1_1	1263	1269	PF00069	0.510
MOD_CK1_1	1448	1454	PF00069	0.340
MOD_CK1_1	159	165	PF00069	0.557
MOD_CK1_1	1653	1659	PF00069	0.443
MOD_CK1_1	19	25	PF00069	0.492
MOD_CK1_1	1938	1944	PF00069	0.524
MOD_CK1_1	51	57	PF00069	0.598
MOD_CK1_1	779	785	PF00069	0.386
MOD_CK1_1	862	868	PF00069	0.506
MOD_CK1_1	887	893	PF00069	0.461
MOD_CK2_1	1061	1067	PF00069	0.508
MOD_CK2_1	1221	1227	PF00069	0.529
MOD_CK2_1	1244	1250	PF00069	0.443
MOD_CK2_1	1448	1454	PF00069	0.454
MOD_CK2_1	1666	1672	PF00069	0.504
MOD_CK2_1	1872	1878	PF00069	0.526
MOD_CK2_1	2	8	PF00069	0.410
MOD_CK2_1	262	268	PF00069	0.393
MOD_CK2_1	283	289	PF00069	0.548
MOD_CK2_1	370	376	PF00069	0.443
MOD_CK2_1	382	388	PF00069	0.443
MOD_CK2_1	395	401	PF00069	0.443
MOD_CK2_1	558	564	PF00069	0.482
MOD_CK2_1	593	599	PF00069	0.366
MOD_CK2_1	710	716	PF00069	0.356
MOD_CK2_1	825	831	PF00069	0.468
MOD_CK2_1	862	868	PF00069	0.454
MOD_CK2_1	976	982	PF00069	0.461
MOD_Cter_Amidation	1193	1196	PF01082	0.329
MOD_GlcNHglycan	1035	1039	PF01048	0.315
MOD_GlcNHglycan	1174	1177	PF01048	0.243
MOD_GlcNHglycan	1227	1231	PF01048	0.243
MOD_GlcNHglycan	1235	1239	PF01048	0.243
MOD_GlcNHglycan	1546	1549	PF01048	0.343
MOD_GlcNHglycan	1562	1565	PF01048	0.389
MOD_GlcNHglycan	162	165	PF01048	0.518
MOD_GlcNHglycan	1742	1745	PF01048	0.263
MOD_GlcNHglycan	36	39	PF01048	0.526
MOD_GlcNHglycan	449	452	PF01048	0.243
MOD_GlcNHglycan	493	496	PF01048	0.572
MOD_GlcNHglycan	50	53	PF01048	0.414
MOD_GlcNHglycan	560	563	PF01048	0.503
MOD_GlcNHglycan	663	667	PF01048	0.407
MOD_GlcNHglycan	827	830	PF01048	0.273
MOD_GlcNHglycan	861	864	PF01048	0.261
MOD_GlcNHglycan	991	994	PF01048	0.253
MOD_GSK3_1	1030	1037	PF00069	0.468
MOD_GSK3_1	1057	1064	PF00069	0.513
MOD_GSK3_1	1115	1122	PF00069	0.409
MOD_GSK3_1	1156	1163	PF00069	0.540
MOD_GSK3_1	1226	1233	PF00069	0.463
MOD_GSK3_1	1308	1315	PF00069	0.512
MOD_GSK3_1	1383	1390	PF00069	0.360
MOD_GSK3_1	154	161	PF00069	0.521
MOD_GSK3_1	1600	1607	PF00069	0.320
MOD_GSK3_1	1728	1735	PF00069	0.440
MOD_GSK3_1	1736	1743	PF00069	0.447
MOD_GSK3_1	1934	1941	PF00069	0.531
MOD_GSK3_1	1951	1958	PF00069	0.348
MOD_GSK3_1	220	227	PF00069	0.392
MOD_GSK3_1	275	282	PF00069	0.362
MOD_GSK3_1	283	290	PF00069	0.436
MOD_GSK3_1	391	398	PF00069	0.468
MOD_GSK3_1	526	533	PF00069	0.355
MOD_GSK3_1	749	756	PF00069	0.472
MOD_GSK3_1	776	783	PF00069	0.561
MOD_GSK3_1	859	866	PF00069	0.443
MOD_GSK3_1	887	894	PF00069	0.520
MOD_GSK3_1	95	102	PF00069	0.394
MOD_GSK3_1	998	1005	PF00069	0.529
MOD_LATS_1	528	534	PF00433	0.342
MOD_N-GLC_1	1843	1848	PF02516	0.329
MOD_N-GLC_1	350	355	PF02516	0.254
MOD_N-GLC_1	491	496	PF02516	0.600
MOD_N-GLC_1	758	763	PF02516	0.457
MOD_N-GLC_1	949	954	PF02516	0.338
MOD_N-GLC_1	955	960	PF02516	0.318
MOD_N-GLC_2	1355	1357	PF02516	0.400
MOD_N-GLC_2	966	968	PF02516	0.293
MOD_NEK2_1	1	6	PF00069	0.416
MOD_NEK2_1	1383	1388	PF00069	0.376
MOD_NEK2_1	1465	1470	PF00069	0.443
MOD_NEK2_1	1576	1581	PF00069	0.304
MOD_NEK2_1	1605	1610	PF00069	0.325
MOD_NEK2_1	1934	1939	PF00069	0.529
MOD_NEK2_1	222	227	PF00069	0.443
MOD_NEK2_1	275	280	PF00069	0.397
MOD_NEK2_1	292	297	PF00069	0.376
MOD_NEK2_1	370	375	PF00069	0.443
MOD_NEK2_1	377	382	PF00069	0.443
MOD_NEK2_1	449	454	PF00069	0.443
MOD_NEK2_1	483	488	PF00069	0.429
MOD_NEK2_1	490	495	PF00069	0.457
MOD_NEK2_1	526	531	PF00069	0.366
MOD_NEK2_1	610	615	PF00069	0.307
MOD_NEK2_1	66	71	PF00069	0.353
MOD_NEK2_1	662	667	PF00069	0.522
MOD_NEK2_1	715	720	PF00069	0.344
MOD_NEK2_1	721	726	PF00069	0.303
MOD_NEK2_1	757	762	PF00069	0.464
MOD_PIKK_1	1115	1121	PF00454	0.445
MOD_PIKK_1	1151	1157	PF00454	0.447
MOD_PIKK_1	1374	1380	PF00454	0.484
MOD_PIKK_1	156	162	PF00454	0.634
MOD_PIKK_1	176	182	PF00454	0.550
MOD_PIKK_1	292	298	PF00454	0.443
MOD_PIKK_1	377	383	PF00454	0.443
MOD_PIKK_1	629	635	PF00454	0.516
MOD_PIKK_1	689	695	PF00454	0.380
MOD_PIKK_1	73	79	PF00454	0.341
MOD_PIKK_1	830	836	PF00454	0.443
MOD_PIKK_1	868	874	PF00454	0.529
MOD_PK_1	1002	1008	PF00069	0.529
MOD_PK_1	220	226	PF00069	0.407
MOD_PKA_1	1387	1393	PF00069	0.321
MOD_PKA_1	395	401	PF00069	0.468
MOD_PKA_1	530	536	PF00069	0.340
MOD_PKA_1	60	66	PF00069	0.418
MOD_PKA_2	1387	1393	PF00069	0.321
MOD_PKA_2	1728	1734	PF00069	0.382
MOD_PKA_2	1891	1897	PF00069	0.443
MOD_PKA_2	1934	1940	PF00069	0.506
MOD_PKA_2	594	600	PF00069	0.374
MOD_PKA_2	629	635	PF00069	0.395
MOD_PKA_2	753	759	PF00069	0.450
MOD_PKA_2	859	865	PF00069	0.529
MOD_PKA_2	884	890	PF00069	0.548
MOD_PKA_2	95	101	PF00069	0.415
MOD_PKB_1	1933	1941	PF00069	0.548
MOD_Plk_1	1103	1109	PF00069	0.454
MOD_Plk_1	1115	1121	PF00069	0.389
MOD_Plk_1	1234	1240	PF00069	0.468
MOD_Plk_1	1318	1324	PF00069	0.386
MOD_Plk_1	1448	1454	PF00069	0.457
MOD_Plk_1	1785	1791	PF00069	0.504
MOD_Plk_1	1843	1849	PF00069	0.529
MOD_Plk_1	1858	1864	PF00069	0.529
MOD_Plk_1	1877	1883	PF00069	0.478
MOD_Plk_1	220	226	PF00069	0.391
MOD_Plk_1	483	489	PF00069	0.433
MOD_Plk_1	675	681	PF00069	0.442
MOD_Plk_1	715	721	PF00069	0.342
MOD_Plk_1	758	764	PF00069	0.458
MOD_Plk_1	809	815	PF00069	0.443
MOD_Plk_1	830	836	PF00069	0.443
MOD_Plk_2-3	146	152	PF00069	0.376
MOD_Plk_2-3	1872	1878	PF00069	0.340
MOD_Plk_2-3	716	722	PF00069	0.443
MOD_Plk_2-3	776	782	PF00069	0.562
MOD_Plk_4	1156	1162	PF00069	0.505
MOD_Plk_4	1319	1325	PF00069	0.365
MOD_Plk_4	1453	1459	PF00069	0.340
MOD_Plk_4	1493	1499	PF00069	0.454
MOD_Plk_4	1587	1593	PF00069	0.359
MOD_Plk_4	16	22	PF00069	0.404
MOD_Plk_4	1600	1606	PF00069	0.333
MOD_Plk_4	1638	1644	PF00069	0.297
MOD_Plk_4	1645	1651	PF00069	0.429
MOD_Plk_4	1770	1776	PF00069	0.439
MOD_Plk_4	1785	1791	PF00069	0.451
MOD_Plk_4	1877	1883	PF00069	0.480
MOD_Plk_4	1966	1972	PF00069	0.455
MOD_Plk_4	1975	1981	PF00069	0.466
MOD_Plk_4	224	230	PF00069	0.449
MOD_Plk_4	283	289	PF00069	0.446
MOD_Plk_4	483	489	PF00069	0.433
MOD_Plk_4	574	580	PF00069	0.450
MOD_Plk_4	623	629	PF00069	0.359
MOD_Plk_4	710	716	PF00069	0.365
MOD_Plk_4	721	727	PF00069	0.303
MOD_Plk_4	753	759	PF00069	0.450
MOD_Plk_4	809	815	PF00069	0.454
MOD_Plk_4	874	880	PF00069	0.443
MOD_Plk_4	923	929	PF00069	0.485
MOD_ProDKin_1	1069	1075	PF00069	0.529
MOD_ProDKin_1	1125	1131	PF00069	0.435
MOD_ProDKin_1	1230	1236	PF00069	0.461
MOD_ProDKin_1	1245	1251	PF00069	0.401
MOD_ProDKin_1	1372	1378	PF00069	0.368
MOD_ProDKin_1	1595	1601	PF00069	0.352
MOD_ProDKin_1	1711	1717	PF00069	0.443
MOD_ProDKin_1	1951	1957	PF00069	0.493
MOD_ProDKin_1	383	389	PF00069	0.443
MOD_ProDKin_1	39	45	PF00069	0.495
MOD_SUMO_for_1	1908	1911	PF00179	0.468
MOD_SUMO_rev_2	1321	1331	PF00179	0.461
MOD_SUMO_rev_2	146	156	PF00179	0.267
MOD_SUMO_rev_2	1488	1494	PF00179	0.454
MOD_SUMO_rev_2	1736	1744	PF00179	0.457
MOD_SUMO_rev_2	188	198	PF00179	0.509
MOD_SUMO_rev_2	252	260	PF00179	0.588
MOD_SUMO_rev_2	330	336	PF00179	0.480
MOD_SUMO_rev_2	672	677	PF00179	0.331
MOD_SUMO_rev_2	747	753	PF00179	0.420
TRG_DiLeu_BaEn_1	1041	1046	PF01217	0.484
TRG_DiLeu_BaEn_1	1672	1677	PF01217	0.504
TRG_DiLeu_BaEn_2	675	681	PF01217	0.442
TRG_DiLeu_BaEn_4	145	151	PF01217	0.382
TRG_DiLeu_BaEn_4	1681	1687	PF01217	0.468
TRG_DiLeu_BaEn_4	840	846	PF01217	0.451
TRG_DiLeu_BaLyEn_6	139	144	PF01217	0.342
TRG_DiLeu_BaLyEn_6	1851	1856	PF01217	0.454
TRG_DiLeu_BaLyEn_6	404	409	PF01217	0.454
TRG_DiLeu_BaLyEn_6	679	684	PF01217	0.334
TRG_DiLeu_LyEn_5	1672	1677	PF01217	0.521
TRG_ENDOCYTIC_2	1139	1142	PF00928	0.328
TRG_ENDOCYTIC_2	1146	1149	PF00928	0.319
TRG_ENDOCYTIC_2	1158	1161	PF00928	0.411
TRG_ENDOCYTIC_2	126	129	PF00928	0.358
TRG_ENDOCYTIC_2	1368	1371	PF00928	0.436
TRG_ENDOCYTIC_2	1497	1500	PF00928	0.484
TRG_ENDOCYTIC_2	1535	1538	PF00928	0.328
TRG_ENDOCYTIC_2	1540	1543	PF00928	0.324
TRG_ENDOCYTIC_2	1591	1594	PF00928	0.397
TRG_ENDOCYTIC_2	1640	1643	PF00928	0.318
TRG_ENDOCYTIC_2	1649	1652	PF00928	0.422
TRG_ENDOCYTIC_2	1766	1769	PF00928	0.454
TRG_ENDOCYTIC_2	1913	1916	PF00928	0.468
TRG_ENDOCYTIC_2	1970	1973	PF00928	0.454
TRG_ENDOCYTIC_2	1977	1980	PF00928	0.454
TRG_ENDOCYTIC_2	205	208	PF00928	0.393
TRG_ENDOCYTIC_2	456	459	PF00928	0.497
TRG_ENDOCYTIC_2	478	481	PF00928	0.379
TRG_ENDOCYTIC_2	510	513	PF00928	0.388
TRG_ENDOCYTIC_2	555	558	PF00928	0.572
TRG_ENDOCYTIC_2	606	609	PF00928	0.401
TRG_ENDOCYTIC_2	723	726	PF00928	0.320
TRG_ENDOCYTIC_2	755	758	PF00928	0.376
TRG_ENDOCYTIC_2	79	82	PF00928	0.341
TRG_ENDOCYTIC_2	796	799	PF00928	0.504
TRG_ENDOCYTIC_2	925	928	PF00928	0.529
TRG_ER_diArg_1	1214	1217	PF00400	0.359
TRG_ER_diArg_1	1293	1296	PF00400	0.443
TRG_ER_diArg_1	134	137	PF00400	0.437
TRG_ER_diArg_1	1582	1584	PF00400	0.308
TRG_ER_diArg_1	203	205	PF00400	0.542
TRG_ER_diArg_1	354	356	PF00400	0.444
TRG_ER_diArg_1	443	446	PF00400	0.505
TRG_ER_diArg_1	729	732	PF00400	0.312
TRG_ER_diArg_1	806	808	PF00400	0.454
TRG_NES_CRM1_1	1013	1027	PF08389	0.548
TRG_NES_CRM1_1	1693	1709	PF08389	0.504
TRG_NES_CRM1_1	1791	1806	PF08389	0.521
TRG_NES_CRM1_1	1845	1859	PF08389	0.444
TRG_Pf-PMV_PEXEL_1	112	116	PF00026	0.407
TRG_Pf-PMV_PEXEL_1	142	146	PF00026	0.352
TRG_Pf-PMV_PEXEL_1	1450	1454	PF00026	0.329
TRG_Pf-PMV_PEXEL_1	1675	1679	PF00026	0.252
TRG_Pf-PMV_PEXEL_1	206	210	PF00026	0.390
TRG_Pf-PMV_PEXEL_1	318	322	PF00026	0.254
TRG_Pf-PMV_PEXEL_1	364	369	PF00026	0.243
TRG_Pf-PMV_PEXEL_1	375	379	PF00026	0.243
TRG_Pf-PMV_PEXEL_1	909	913	PF00026	0.243
TRG_Pf-PMV_PEXEL_1	994	998	PF00026	0.329

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE72	Leptomonas seymouri	29%	84%
A0A0N1PFB3	Leptomonas seymouri	90%	93%
A0A0S4JCP4	Bodo saltans	62%	99%
A0A0S4JQT9	Bodo saltans	29%	92%
A0A1X0NNT2	Trypanosomatidae	69%	89%
A0A3Q8I9S7	Leishmania donovani	30%	84%
A0A3Q8IBN2	Leishmania donovani	98%	92%
A0A3R7KB93	Trypanosoma rangeli	30%	88%
A0A3S5IRN2	Trypanosoma rangeli	68%	94%
A4H739	Leishmania braziliensis	94%	100%
A4H938	Leishmania braziliensis	30%	84%
A4HVH9	Leishmania infantum	98%	92%
A4HXH0	Leishmania infantum	27%	100%
C9ZP57	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	89%
D0A6T2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	68%	90%
E1BNG3	Bos taurus	45%	90%
E7F8F4	Danio rerio	46%	100%
E9AR65	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	84%
E9PZJ8	Mus musculus	43%	90%
F1LNJ2	Rattus norvegicus	39%	93%
F1LPQ2	Rattus norvegicus	45%	90%
F1NTD6	Gallus gallus	43%	90%
O48534	Arabidopsis thaliana	39%	91%
O60072	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	41%	100%
O75643	Homo sapiens	39%	93%
P32639	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	92%
P53327	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	100%
Q4QE98	Leishmania major	30%	84%
Q4QGA4	Leishmania major	98%	100%
Q54G57	Dictyostelium discoideum	43%	90%
Q55CI8	Dictyostelium discoideum	36%	89%
Q6P4T2	Mus musculus	39%	93%
Q8N3C0	Homo sapiens	42%	90%
Q9FNQ1	Arabidopsis thaliana	43%	92%
Q9SYP1	Arabidopsis thaliana	39%	91%
Q9U2G0	Caenorhabditis elegans	38%	93%
Q9UT24	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	91%
Q9VUV9	Drosophila melanogaster	39%	93%
V5D6H9	Trypanosoma cruzi	30%	89%
V5DBI1	Trypanosoma cruzi	69%	98%