LeishMANIAdb
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Sister chromatid cohesion protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Sister chromatid cohesion protein
Gene product:
Sister chromatid cohesion C-terminus, putative
Species:
Leishmania mexicana
UniProt:
E9AP64_LEIMU
TriTrypDb:
LmxM.13.0400
Length:
2024

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 9
GO:0043226 organelle 2 9
GO:0043227 membrane-bounded organelle 3 9
GO:0043229 intracellular organelle 3 9
GO:0043231 intracellular membrane-bounded organelle 4 9
GO:0110165 cellular anatomical entity 1 9
GO:0032116 SMC loading complex 3 1
GO:0032991 protein-containing complex 1 1
GO:0090694 Scc2-Scc4 cohesin loading complex 4 1
GO:0140513 nuclear protein-containing complex 2 1

Expansion

Sequence features

E9AP64
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0008104 protein localization 4 10
GO:0009987 cellular process 1 10
GO:0010468 regulation of gene expression 5 10
GO:0019222 regulation of metabolic process 3 10
GO:0022402 cell cycle process 2 10
GO:0033036 macromolecule localization 2 10
GO:0033365 protein localization to organelle 5 10
GO:0034502 protein localization to chromosome 6 10
GO:0050789 regulation of biological process 2 10
GO:0051179 localization 1 10
GO:0051641 cellular localization 2 10
GO:0060255 regulation of macromolecule metabolic process 4 10
GO:0061780 mitotic cohesin loading 4 10
GO:0065007 biological regulation 1 10
GO:0070727 cellular macromolecule localization 3 10
GO:0071168 protein localization to chromatin 7 10
GO:0071921 cohesin loading 3 10
GO:1903047 mitotic cell cycle process 3 10
GO:0000724 double-strand break repair via homologous recombination 7 1
GO:0000725 recombinational repair 6 1
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006259 DNA metabolic process 4 1
GO:0006281 DNA repair 5 1
GO:0006302 double-strand break repair 6 1
GO:0006310 DNA recombination 5 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0006950 response to stress 2 1
GO:0006974 DNA damage response 4 1
GO:0008152 metabolic process 1 1
GO:0033554 cellular response to stress 3 1
GO:0034085 establishment of sister chromatid cohesion 3 1
GO:0034087 establishment of mitotic sister chromatid cohesion 4 1
GO:0034641 cellular nitrogen compound metabolic process 3 1
GO:0043170 macromolecule metabolic process 3 1
GO:0044237 cellular metabolic process 2 1
GO:0044238 primary metabolic process 2 1
GO:0044260 obsolete cellular macromolecule metabolic process 3 1
GO:0045184 establishment of protein localization 3 1
GO:0046483 heterocycle metabolic process 3 1
GO:0050896 response to stimulus 1 1
GO:0051234 establishment of localization 2 1
GO:0051716 cellular response to stimulus 2 1
GO:0070199 establishment of protein localization to chromosome 5 1
GO:0071169 establishment of protein localization to chromatin 6 1
GO:0071704 organic substance metabolic process 2 1
GO:0072594 establishment of protein localization to organelle 4 1
GO:0090304 nucleic acid metabolic process 4 1
GO:1901360 organic cyclic compound metabolic process 3 1
GO:1990414 replication-born double-strand break repair via sister chromatid exchange 8 1
Molecular functions
Term Name Level Count
GO:0003682 chromatin binding 2 10
GO:0005488 binding 1 10

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1062 1066 PF00656 0.279
CLV_C14_Caspase3-7 116 120 PF00656 0.581
CLV_C14_Caspase3-7 1491 1495 PF00656 0.488
CLV_C14_Caspase3-7 1805 1809 PF00656 0.580
CLV_C14_Caspase3-7 1986 1990 PF00656 0.582
CLV_C14_Caspase3-7 288 292 PF00656 0.441
CLV_C14_Caspase3-7 772 776 PF00656 0.262
CLV_C14_Caspase3-7 819 823 PF00656 0.456
CLV_NRD_NRD_1 1057 1059 PF00675 0.275
CLV_NRD_NRD_1 1137 1139 PF00675 0.408
CLV_NRD_NRD_1 1461 1463 PF00675 0.369
CLV_NRD_NRD_1 163 165 PF00675 0.564
CLV_NRD_NRD_1 1829 1831 PF00675 0.256
CLV_NRD_NRD_1 1868 1870 PF00675 0.384
CLV_NRD_NRD_1 1955 1957 PF00675 0.507
CLV_NRD_NRD_1 1963 1965 PF00675 0.522
CLV_NRD_NRD_1 2011 2013 PF00675 0.557
CLV_NRD_NRD_1 213 215 PF00675 0.426
CLV_NRD_NRD_1 572 574 PF00675 0.338
CLV_NRD_NRD_1 622 624 PF00675 0.289
CLV_PCSK_FUR_1 1507 1511 PF00082 0.449
CLV_PCSK_FUR_1 1963 1967 PF00082 0.590
CLV_PCSK_FUR_1 211 215 PF00082 0.450
CLV_PCSK_KEX2_1 1057 1059 PF00082 0.282
CLV_PCSK_KEX2_1 1136 1138 PF00082 0.419
CLV_PCSK_KEX2_1 1509 1511 PF00082 0.613
CLV_PCSK_KEX2_1 1514 1516 PF00082 0.541
CLV_PCSK_KEX2_1 1697 1699 PF00082 0.259
CLV_PCSK_KEX2_1 1829 1831 PF00082 0.233
CLV_PCSK_KEX2_1 1868 1870 PF00082 0.430
CLV_PCSK_KEX2_1 1963 1965 PF00082 0.523
CLV_PCSK_KEX2_1 2011 2013 PF00082 0.561
CLV_PCSK_KEX2_1 213 215 PF00082 0.444
CLV_PCSK_KEX2_1 572 574 PF00082 0.338
CLV_PCSK_KEX2_1 622 624 PF00082 0.336
CLV_PCSK_KEX2_1 905 907 PF00082 0.266
CLV_PCSK_PC1ET2_1 1509 1511 PF00082 0.470
CLV_PCSK_PC1ET2_1 1514 1516 PF00082 0.595
CLV_PCSK_PC1ET2_1 1697 1699 PF00082 0.259
CLV_PCSK_PC1ET2_1 1965 1967 PF00082 0.553
CLV_PCSK_PC1ET2_1 905 907 PF00082 0.266
CLV_PCSK_PC7_1 1510 1516 PF00082 0.431
CLV_PCSK_SKI1_1 1053 1057 PF00082 0.319
CLV_PCSK_SKI1_1 1249 1253 PF00082 0.295
CLV_PCSK_SKI1_1 1310 1314 PF00082 0.337
CLV_PCSK_SKI1_1 1328 1332 PF00082 0.171
CLV_PCSK_SKI1_1 138 142 PF00082 0.471
CLV_PCSK_SKI1_1 1428 1432 PF00082 0.361
CLV_PCSK_SKI1_1 1462 1466 PF00082 0.395
CLV_PCSK_SKI1_1 1524 1528 PF00082 0.512
CLV_PCSK_SKI1_1 1583 1587 PF00082 0.212
CLV_PCSK_SKI1_1 1726 1730 PF00082 0.312
CLV_PCSK_SKI1_1 1956 1960 PF00082 0.641
CLV_PCSK_SKI1_1 27 31 PF00082 0.364
CLV_PCSK_SKI1_1 573 577 PF00082 0.257
CLV_PCSK_SKI1_1 733 737 PF00082 0.390
CLV_PCSK_SKI1_1 765 769 PF00082 0.342
CLV_PCSK_SKI1_1 905 909 PF00082 0.322
CLV_PCSK_SKI1_1 992 996 PF00082 0.191
DEG_APCC_DBOX_1 1237 1245 PF00400 0.218
DEG_APCC_DBOX_1 1309 1317 PF00400 0.328
DEG_APCC_DBOX_1 153 161 PF00400 0.428
DEG_APCC_DBOX_1 186 194 PF00400 0.562
DEG_APCC_DBOX_1 542 550 PF00400 0.247
DEG_APCC_DBOX_1 732 740 PF00400 0.383
DEG_APCC_DBOX_1 875 883 PF00400 0.337
DEG_MDM2_SWIB_1 1055 1063 PF02201 0.364
DEG_SPOP_SBC_1 170 174 PF00917 0.454
DEG_SPOP_SBC_1 1736 1740 PF00917 0.229
DEG_SPOP_SBC_1 253 257 PF00917 0.633
DEG_SPOP_SBC_1 361 365 PF00917 0.380
DOC_CDC14_PxL_1 1761 1769 PF14671 0.164
DOC_CKS1_1 1017 1022 PF01111 0.242
DOC_CKS1_1 1933 1938 PF01111 0.427
DOC_CYCLIN_RxL_1 1029 1040 PF00134 0.298
DOC_CYCLIN_RxL_1 1307 1315 PF00134 0.438
DOC_CYCLIN_RxL_1 1325 1335 PF00134 0.169
DOC_CYCLIN_RxL_1 1826 1835 PF00134 0.208
DOC_CYCLIN_RxL_1 24 31 PF00134 0.415
DOC_CYCLIN_RxL_1 685 693 PF00134 0.273
DOC_CYCLIN_yCln2_LP_2 1593 1596 PF00134 0.216
DOC_CYCLIN_yCln2_LP_2 1747 1753 PF00134 0.229
DOC_CYCLIN_yCln2_LP_2 740 746 PF00134 0.270
DOC_MAPK_DCC_7 1235 1244 PF00069 0.241
DOC_MAPK_DCC_7 572 580 PF00069 0.189
DOC_MAPK_DCC_7 939 949 PF00069 0.282
DOC_MAPK_gen_1 1057 1063 PF00069 0.413
DOC_MAPK_gen_1 1235 1244 PF00069 0.342
DOC_MAPK_gen_1 1514 1522 PF00069 0.494
DOC_MAPK_gen_1 1816 1825 PF00069 0.245
DOC_MAPK_gen_1 409 419 PF00069 0.258
DOC_MAPK_gen_1 543 551 PF00069 0.250
DOC_MAPK_gen_1 572 580 PF00069 0.189
DOC_MAPK_gen_1 939 947 PF00069 0.268
DOC_MAPK_HePTP_8 1395 1407 PF00069 0.232
DOC_MAPK_JIP1_4 688 694 PF00069 0.257
DOC_MAPK_MEF2A_6 1079 1086 PF00069 0.286
DOC_MAPK_MEF2A_6 1235 1244 PF00069 0.497
DOC_MAPK_MEF2A_6 1398 1407 PF00069 0.252
DOC_MAPK_MEF2A_6 1578 1586 PF00069 0.212
DOC_MAPK_MEF2A_6 412 421 PF00069 0.262
DOC_MAPK_MEF2A_6 543 551 PF00069 0.367
DOC_MAPK_MEF2A_6 572 580 PF00069 0.342
DOC_MAPK_MEF2A_6 890 899 PF00069 0.455
DOC_MAPK_MEF2A_6 941 949 PF00069 0.265
DOC_MAPK_NFAT4_5 573 581 PF00069 0.342
DOC_PP1_RVXF_1 1828 1835 PF00149 0.185
DOC_PP2B_LxvP_1 1234 1237 PF13499 0.272
DOC_PP2B_LxvP_1 1499 1502 PF13499 0.495
DOC_PP2B_LxvP_1 1593 1596 PF13499 0.216
DOC_PP2B_LxvP_1 650 653 PF13499 0.297
DOC_PP2B_LxvP_1 740 743 PF13499 0.261
DOC_PP4_FxxP_1 1017 1020 PF00568 0.331
DOC_PP4_FxxP_1 32 35 PF00568 0.287
DOC_PP4_FxxP_1 708 711 PF00568 0.245
DOC_USP7_MATH_1 1066 1070 PF00917 0.307
DOC_USP7_MATH_1 1156 1160 PF00917 0.331
DOC_USP7_MATH_1 117 121 PF00917 0.527
DOC_USP7_MATH_1 1430 1434 PF00917 0.449
DOC_USP7_MATH_1 1618 1622 PF00917 0.317
DOC_USP7_MATH_1 170 174 PF00917 0.454
DOC_USP7_MATH_1 1736 1740 PF00917 0.360
DOC_USP7_MATH_1 18 22 PF00917 0.318
DOC_USP7_MATH_1 1807 1811 PF00917 0.536
DOC_USP7_MATH_1 1859 1863 PF00917 0.483
DOC_USP7_MATH_1 1958 1962 PF00917 0.418
DOC_USP7_MATH_1 212 216 PF00917 0.568
DOC_USP7_MATH_1 223 227 PF00917 0.381
DOC_USP7_MATH_1 254 258 PF00917 0.661
DOC_USP7_MATH_1 290 294 PF00917 0.336
DOC_USP7_MATH_1 305 309 PF00917 0.355
DOC_USP7_MATH_1 360 364 PF00917 0.427
DOC_USP7_MATH_1 454 458 PF00917 0.274
DOC_USP7_MATH_1 459 463 PF00917 0.229
DOC_USP7_MATH_1 5 9 PF00917 0.452
DOC_USP7_MATH_1 555 559 PF00917 0.240
DOC_USP7_MATH_1 61 65 PF00917 0.532
DOC_USP7_MATH_1 66 70 PF00917 0.536
DOC_USP7_MATH_1 832 836 PF00917 0.383
DOC_USP7_UBL2_3 1049 1053 PF12436 0.328
DOC_WW_Pin1_4 1016 1021 PF00397 0.245
DOC_WW_Pin1_4 1207 1212 PF00397 0.392
DOC_WW_Pin1_4 1390 1395 PF00397 0.257
DOC_WW_Pin1_4 1537 1542 PF00397 0.532
DOC_WW_Pin1_4 1569 1574 PF00397 0.229
DOC_WW_Pin1_4 1737 1742 PF00397 0.244
DOC_WW_Pin1_4 1895 1900 PF00397 0.417
DOC_WW_Pin1_4 1932 1937 PF00397 0.440
DOC_WW_Pin1_4 1990 1995 PF00397 0.573
LIG_14-3-3_CanoR_1 1058 1064 PF00244 0.335
LIG_14-3-3_CanoR_1 1249 1258 PF00244 0.242
LIG_14-3-3_CanoR_1 129 136 PF00244 0.351
LIG_14-3-3_CanoR_1 138 147 PF00244 0.430
LIG_14-3-3_CanoR_1 1406 1412 PF00244 0.241
LIG_14-3-3_CanoR_1 1462 1470 PF00244 0.326
LIG_14-3-3_CanoR_1 154 158 PF00244 0.316
LIG_14-3-3_CanoR_1 1567 1573 PF00244 0.316
LIG_14-3-3_CanoR_1 1726 1735 PF00244 0.212
LIG_14-3-3_CanoR_1 1829 1833 PF00244 0.317
LIG_14-3-3_CanoR_1 1868 1872 PF00244 0.409
LIG_14-3-3_CanoR_1 1932 1936 PF00244 0.618
LIG_14-3-3_CanoR_1 267 272 PF00244 0.484
LIG_14-3-3_CanoR_1 36 43 PF00244 0.322
LIG_14-3-3_CanoR_1 442 448 PF00244 0.535
LIG_14-3-3_CanoR_1 553 561 PF00244 0.243
LIG_14-3-3_CanoR_1 572 576 PF00244 0.335
LIG_14-3-3_CanoR_1 606 611 PF00244 0.250
LIG_14-3-3_CanoR_1 622 630 PF00244 0.238
LIG_14-3-3_CanoR_1 770 779 PF00244 0.261
LIG_14-3-3_CanoR_1 874 880 PF00244 0.287
LIG_14-3-3_CanoR_1 913 921 PF00244 0.266
LIG_Actin_WH2_1 876 892 PF00022 0.250
LIG_Actin_WH2_2 1684 1702 PF00022 0.229
LIG_Actin_WH2_2 1880 1898 PF00022 0.368
LIG_Actin_WH2_2 875 892 PF00022 0.250
LIG_APCC_ABBA_1 1622 1627 PF00400 0.212
LIG_APCC_ABBA_1 331 336 PF00400 0.200
LIG_APCC_ABBA_1 700 705 PF00400 0.416
LIG_BIR_II_1 1 5 PF00653 0.433
LIG_BIR_III_2 1991 1995 PF00653 0.455
LIG_BIR_III_4 1065 1069 PF00653 0.300
LIG_BIR_III_4 891 895 PF00653 0.256
LIG_BRCT_BRCA1_1 1741 1745 PF00533 0.212
LIG_BRCT_BRCA1_1 1830 1834 PF00533 0.184
LIG_BRCT_BRCA1_1 293 297 PF00533 0.386
LIG_BRCT_BRCA1_1 862 866 PF00533 0.515
LIG_Clathr_ClatBox_1 1241 1245 PF01394 0.295
LIG_eIF4E_1 1325 1331 PF01652 0.225
LIG_EVH1_1 1204 1208 PF00568 0.325
LIG_FAT_LD_1 1884 1892 PF03623 0.310
LIG_FHA_1 1207 1213 PF00498 0.435
LIG_FHA_1 1250 1256 PF00498 0.243
LIG_FHA_1 1378 1384 PF00498 0.354
LIG_FHA_1 139 145 PF00498 0.345
LIG_FHA_1 1415 1421 PF00498 0.439
LIG_FHA_1 1467 1473 PF00498 0.400
LIG_FHA_1 1703 1709 PF00498 0.316
LIG_FHA_1 1756 1762 PF00498 0.232
LIG_FHA_1 1875 1881 PF00498 0.417
LIG_FHA_1 1935 1941 PF00498 0.480
LIG_FHA_1 257 263 PF00498 0.454
LIG_FHA_1 341 347 PF00498 0.271
LIG_FHA_1 390 396 PF00498 0.385
LIG_FHA_1 483 489 PF00498 0.310
LIG_FHA_1 520 526 PF00498 0.445
LIG_FHA_1 563 569 PF00498 0.235
LIG_FHA_1 645 651 PF00498 0.361
LIG_FHA_1 857 863 PF00498 0.371
LIG_FHA_1 976 982 PF00498 0.256
LIG_FHA_2 1060 1066 PF00498 0.277
LIG_FHA_2 1670 1676 PF00498 0.226
LIG_FHA_2 1779 1785 PF00498 0.329
LIG_FHA_2 1974 1980 PF00498 0.499
LIG_FHA_2 1984 1990 PF00498 0.516
LIG_FHA_2 2002 2008 PF00498 0.640
LIG_FHA_2 268 274 PF00498 0.588
LIG_FHA_2 294 300 PF00498 0.357
LIG_FHA_2 352 358 PF00498 0.538
LIG_FHA_2 796 802 PF00498 0.364
LIG_FHA_2 956 962 PF00498 0.406
LIG_GBD_Chelix_1 1247 1255 PF00786 0.241
LIG_GBD_Chelix_1 642 650 PF00786 0.281
LIG_GBD_Chelix_1 981 989 PF00786 0.285
LIG_GSK3_LRP6_1 1207 1212 PF00069 0.347
LIG_LIR_Apic_2 1189 1193 PF02991 0.257
LIG_LIR_Apic_2 1201 1207 PF02991 0.310
LIG_LIR_Apic_2 1256 1261 PF02991 0.227
LIG_LIR_Apic_2 31 35 PF02991 0.309
LIG_LIR_Apic_2 44 50 PF02991 0.422
LIG_LIR_Apic_2 705 711 PF02991 0.241
LIG_LIR_Gen_1 1010 1020 PF02991 0.256
LIG_LIR_Gen_1 1162 1171 PF02991 0.342
LIG_LIR_Gen_1 1304 1314 PF02991 0.284
LIG_LIR_Gen_1 1326 1337 PF02991 0.223
LIG_LIR_Gen_1 1380 1388 PF02991 0.372
LIG_LIR_Gen_1 1555 1566 PF02991 0.316
LIG_LIR_Gen_1 1689 1699 PF02991 0.466
LIG_LIR_Gen_1 1909 1919 PF02991 0.371
LIG_LIR_Gen_1 294 305 PF02991 0.434
LIG_LIR_Gen_1 405 415 PF02991 0.458
LIG_LIR_Gen_1 499 508 PF02991 0.229
LIG_LIR_Gen_1 548 559 PF02991 0.267
LIG_LIR_Gen_1 801 809 PF02991 0.364
LIG_LIR_Gen_1 815 823 PF02991 0.305
LIG_LIR_Gen_1 92 103 PF02991 0.351
LIG_LIR_Nem_3 1010 1016 PF02991 0.237
LIG_LIR_Nem_3 1159 1164 PF02991 0.291
LIG_LIR_Nem_3 1304 1309 PF02991 0.267
LIG_LIR_Nem_3 1326 1332 PF02991 0.300
LIG_LIR_Nem_3 1380 1384 PF02991 0.358
LIG_LIR_Nem_3 1555 1561 PF02991 0.316
LIG_LIR_Nem_3 1689 1695 PF02991 0.466
LIG_LIR_Nem_3 1742 1748 PF02991 0.349
LIG_LIR_Nem_3 1909 1915 PF02991 0.387
LIG_LIR_Nem_3 294 300 PF02991 0.411
LIG_LIR_Nem_3 325 329 PF02991 0.363
LIG_LIR_Nem_3 405 410 PF02991 0.462
LIG_LIR_Nem_3 499 505 PF02991 0.229
LIG_LIR_Nem_3 548 554 PF02991 0.289
LIG_LIR_Nem_3 801 805 PF02991 0.287
LIG_LIR_Nem_3 815 820 PF02991 0.294
LIG_LIR_Nem_3 92 98 PF02991 0.323
LIG_MYND_3 464 468 PF01753 0.303
LIG_NRBOX 1250 1256 PF00104 0.270
LIG_NRBOX 143 149 PF00104 0.363
LIG_NRBOX 645 651 PF00104 0.501
LIG_NRBOX 832 838 PF00104 0.260
LIG_NRBOX 984 990 PF00104 0.256
LIG_PCNA_PIPBox_1 1048 1057 PF02747 0.304
LIG_PCNA_yPIPBox_3 830 841 PF02747 0.313
LIG_PDZ_Class_3 2019 2024 PF00595 0.489
LIG_Pex14_1 611 615 PF04695 0.244
LIG_Pex14_2 1055 1059 PF04695 0.268
LIG_PTB_Apo_2 1300 1307 PF02174 0.232
LIG_PTB_Phospho_1 1300 1306 PF10480 0.231
LIG_REV1ctd_RIR_1 548 554 PF16727 0.280
LIG_SH2_CRK 1013 1017 PF00017 0.282
LIG_SH2_CRK 1306 1310 PF00017 0.340
LIG_SH2_CRK 1692 1696 PF00017 0.316
LIG_SH2_CRK 502 506 PF00017 0.307
LIG_SH2_PTP2 1258 1261 PF00017 0.226
LIG_SH2_SRC 1116 1119 PF00017 0.356
LIG_SH2_STAP1 1325 1329 PF00017 0.226
LIG_SH2_STAP1 520 524 PF00017 0.238
LIG_SH2_STAP1 802 806 PF00017 0.338
LIG_SH2_STAT5 1112 1115 PF00017 0.315
LIG_SH2_STAT5 1258 1261 PF00017 0.226
LIG_SH2_STAT5 1294 1297 PF00017 0.232
LIG_SH2_STAT5 1306 1309 PF00017 0.245
LIG_SH2_STAT5 1325 1328 PF00017 0.226
LIG_SH2_STAT5 1419 1422 PF00017 0.320
LIG_SH2_STAT5 1692 1695 PF00017 0.330
LIG_SH2_STAT5 1827 1830 PF00017 0.331
LIG_SH2_STAT5 523 526 PF00017 0.317
LIG_SH2_STAT5 786 789 PF00017 0.336
LIG_SH2_STAT5 924 927 PF00017 0.338
LIG_SH2_STAT5 987 990 PF00017 0.251
LIG_SH3_1 1344 1350 PF00018 0.432
LIG_SH3_3 1087 1093 PF00018 0.366
LIG_SH3_3 1202 1208 PF00018 0.422
LIG_SH3_3 1210 1216 PF00018 0.411
LIG_SH3_3 1234 1240 PF00018 0.231
LIG_SH3_3 1287 1293 PF00018 0.334
LIG_SH3_3 1344 1350 PF00018 0.504
LIG_SH3_3 1517 1523 PF00018 0.422
LIG_SH3_3 1535 1541 PF00018 0.508
LIG_SH3_3 1607 1613 PF00018 0.316
LIG_SH3_3 1659 1665 PF00018 0.293
LIG_SH3_3 236 242 PF00018 0.498
LIG_SH3_3 385 391 PF00018 0.350
LIG_SH3_3 650 656 PF00018 0.295
LIG_SH3_3 892 898 PF00018 0.273
LIG_SUMO_SIM_anti_2 1080 1086 PF11976 0.239
LIG_SUMO_SIM_anti_2 1920 1927 PF11976 0.329
LIG_SUMO_SIM_par_1 1059 1065 PF11976 0.361
LIG_SUMO_SIM_par_1 1240 1245 PF11976 0.223
LIG_SUMO_SIM_par_1 1757 1763 PF11976 0.360
LIG_SUMO_SIM_par_1 576 581 PF11976 0.254
LIG_SUMO_SIM_par_1 688 693 PF11976 0.364
LIG_SUMO_SIM_par_1 869 875 PF11976 0.265
LIG_SUMO_SIM_par_1 945 950 PF11976 0.281
LIG_TRAF2_1 50 53 PF00917 0.416
LIG_TRAF2_1 823 826 PF00917 0.301
LIG_TYR_ITIM 1292 1297 PF00017 0.330
LIG_TYR_ITIM 500 505 PF00017 0.307
LIG_TYR_ITSM 1302 1309 PF00017 0.272
LIG_UBA3_1 1025 1032 PF00899 0.276
LIG_UBA3_1 882 890 PF00899 0.252
LIG_UBA3_1 985 992 PF00899 0.252
LIG_WRC_WIRS_1 404 409 PF05994 0.414
LIG_WRC_WIRS_1 662 667 PF05994 0.279
MOD_CDK_SPxK_1 1932 1938 PF00069 0.442
MOD_CDK_SPxxK_3 1207 1214 PF00069 0.349
MOD_CK1_1 1123 1129 PF00069 0.448
MOD_CK1_1 113 119 PF00069 0.420
MOD_CK1_1 1159 1165 PF00069 0.394
MOD_CK1_1 1270 1276 PF00069 0.452
MOD_CK1_1 1315 1321 PF00069 0.311
MOD_CK1_1 1390 1396 PF00069 0.246
MOD_CK1_1 1444 1450 PF00069 0.482
MOD_CK1_1 1483 1489 PF00069 0.558
MOD_CK1_1 149 155 PF00069 0.309
MOD_CK1_1 1493 1499 PF00069 0.663
MOD_CK1_1 1569 1575 PF00069 0.468
MOD_CK1_1 1683 1689 PF00069 0.485
MOD_CK1_1 169 175 PF00069 0.461
MOD_CK1_1 1690 1696 PF00069 0.363
MOD_CK1_1 1702 1708 PF00069 0.181
MOD_CK1_1 1739 1745 PF00069 0.289
MOD_CK1_1 1874 1880 PF00069 0.391
MOD_CK1_1 1898 1904 PF00069 0.430
MOD_CK1_1 1934 1940 PF00069 0.501
MOD_CK1_1 1970 1976 PF00069 0.548
MOD_CK1_1 1996 2002 PF00069 0.535
MOD_CK1_1 215 221 PF00069 0.522
MOD_CK1_1 240 246 PF00069 0.617
MOD_CK1_1 255 261 PF00069 0.580
MOD_CK1_1 293 299 PF00069 0.367
MOD_CK1_1 308 314 PF00069 0.336
MOD_CK1_1 347 353 PF00069 0.277
MOD_CK1_1 364 370 PF00069 0.399
MOD_CK1_1 372 378 PF00069 0.288
MOD_CK1_1 675 681 PF00069 0.457
MOD_CK1_1 724 730 PF00069 0.358
MOD_CK1_1 769 775 PF00069 0.321
MOD_CK1_1 869 875 PF00069 0.300
MOD_CK2_1 1035 1041 PF00069 0.433
MOD_CK2_1 1924 1930 PF00069 0.426
MOD_CK2_1 267 273 PF00069 0.506
MOD_CK2_1 349 355 PF00069 0.381
MOD_CK2_1 955 961 PF00069 0.397
MOD_GlcNHglycan 1 4 PF01048 0.641
MOD_GlcNHglycan 115 118 PF01048 0.415
MOD_GlcNHglycan 119 122 PF01048 0.378
MOD_GlcNHglycan 1274 1277 PF01048 0.257
MOD_GlcNHglycan 1286 1289 PF01048 0.244
MOD_GlcNHglycan 130 133 PF01048 0.303
MOD_GlcNHglycan 1476 1479 PF01048 0.473
MOD_GlcNHglycan 1486 1489 PF01048 0.568
MOD_GlcNHglycan 1550 1553 PF01048 0.363
MOD_GlcNHglycan 1657 1660 PF01048 0.216
MOD_GlcNHglycan 168 171 PF01048 0.538
MOD_GlcNHglycan 1682 1685 PF01048 0.293
MOD_GlcNHglycan 173 176 PF01048 0.567
MOD_GlcNHglycan 1808 1812 PF01048 0.390
MOD_GlcNHglycan 183 186 PF01048 0.521
MOD_GlcNHglycan 1839 1842 PF01048 0.418
MOD_GlcNHglycan 1861 1864 PF01048 0.394
MOD_GlcNHglycan 1873 1876 PF01048 0.379
MOD_GlcNHglycan 1925 1929 PF01048 0.581
MOD_GlcNHglycan 1942 1945 PF01048 0.604
MOD_GlcNHglycan 1972 1975 PF01048 0.480
MOD_GlcNHglycan 1996 1999 PF01048 0.523
MOD_GlcNHglycan 214 217 PF01048 0.430
MOD_GlcNHglycan 219 222 PF01048 0.421
MOD_GlcNHglycan 243 246 PF01048 0.616
MOD_GlcNHglycan 249 252 PF01048 0.735
MOD_GlcNHglycan 273 276 PF01048 0.629
MOD_GlcNHglycan 307 310 PF01048 0.503
MOD_GlcNHglycan 346 349 PF01048 0.298
MOD_GlcNHglycan 366 369 PF01048 0.369
MOD_GlcNHglycan 374 377 PF01048 0.267
MOD_GlcNHglycan 423 426 PF01048 0.280
MOD_GlcNHglycan 431 435 PF01048 0.447
MOD_GlcNHglycan 451 454 PF01048 0.555
MOD_GlcNHglycan 526 529 PF01048 0.326
MOD_GlcNHglycan 557 560 PF01048 0.326
MOD_GlcNHglycan 63 67 PF01048 0.516
MOD_GlcNHglycan 674 677 PF01048 0.355
MOD_GlcNHglycan 682 685 PF01048 0.328
MOD_GlcNHglycan 84 87 PF01048 0.343
MOD_GlcNHglycan 914 917 PF01048 0.337
MOD_GlcNHglycan 935 939 PF01048 0.291
MOD_GlcNHglycan 963 966 PF01048 0.511
MOD_GlcNHglycan 970 973 PF01048 0.568
MOD_GlcNHglycan 991 995 PF01048 0.245
MOD_GSK3_1 1119 1126 PF00069 0.408
MOD_GSK3_1 113 120 PF00069 0.550
MOD_GSK3_1 1162 1169 PF00069 0.417
MOD_GSK3_1 1172 1179 PF00069 0.222
MOD_GSK3_1 1249 1256 PF00069 0.226
MOD_GSK3_1 1272 1279 PF00069 0.314
MOD_GSK3_1 1297 1304 PF00069 0.346
MOD_GSK3_1 1315 1322 PF00069 0.232
MOD_GSK3_1 134 141 PF00069 0.455
MOD_GSK3_1 1430 1437 PF00069 0.342
MOD_GSK3_1 1462 1469 PF00069 0.398
MOD_GSK3_1 1480 1487 PF00069 0.426
MOD_GSK3_1 149 156 PF00069 0.512
MOD_GSK3_1 1548 1555 PF00069 0.357
MOD_GSK3_1 166 173 PF00069 0.578
MOD_GSK3_1 1683 1690 PF00069 0.361
MOD_GSK3_1 1699 1706 PF00069 0.206
MOD_GSK3_1 1731 1738 PF00069 0.212
MOD_GSK3_1 1798 1805 PF00069 0.445
MOD_GSK3_1 1867 1874 PF00069 0.540
MOD_GSK3_1 1897 1904 PF00069 0.518
MOD_GSK3_1 1968 1975 PF00069 0.559
MOD_GSK3_1 1990 1997 PF00069 0.537
MOD_GSK3_1 237 244 PF00069 0.488
MOD_GSK3_1 252 259 PF00069 0.545
MOD_GSK3_1 267 274 PF00069 0.391
MOD_GSK3_1 305 312 PF00069 0.458
MOD_GSK3_1 340 347 PF00069 0.270
MOD_GSK3_1 351 358 PF00069 0.294
MOD_GSK3_1 360 367 PF00069 0.342
MOD_GSK3_1 454 461 PF00069 0.332
MOD_GSK3_1 506 513 PF00069 0.394
MOD_GSK3_1 585 592 PF00069 0.355
MOD_GSK3_1 62 69 PF00069 0.585
MOD_GSK3_1 661 668 PF00069 0.444
MOD_GSK3_1 721 728 PF00069 0.372
MOD_GSK3_1 765 772 PF00069 0.425
MOD_GSK3_1 787 794 PF00069 0.315
MOD_GSK3_1 812 819 PF00069 0.285
MOD_GSK3_1 850 857 PF00069 0.360
MOD_GSK3_1 860 867 PF00069 0.296
MOD_GSK3_1 878 885 PF00069 0.266
MOD_GSK3_1 89 96 PF00069 0.350
MOD_GSK3_1 953 960 PF00069 0.331
MOD_LATS_1 1724 1730 PF00433 0.212
MOD_LATS_1 387 393 PF00433 0.326
MOD_N-GLC_1 166 171 PF02516 0.365
MOD_N-GLC_1 1847 1852 PF02516 0.339
MOD_N-GLC_1 2015 2020 PF02516 0.459
MOD_N-GLC_1 850 855 PF02516 0.326
MOD_NEK2_1 1198 1203 PF00069 0.337
MOD_NEK2_1 1226 1231 PF00069 0.313
MOD_NEK2_1 1297 1302 PF00069 0.224
MOD_NEK2_1 1353 1358 PF00069 0.466
MOD_NEK2_1 1377 1382 PF00069 0.347
MOD_NEK2_1 147 152 PF00069 0.444
MOD_NEK2_1 1474 1479 PF00069 0.501
MOD_NEK2_1 1647 1652 PF00069 0.300
MOD_NEK2_1 1655 1660 PF00069 0.236
MOD_NEK2_1 1666 1671 PF00069 0.167
MOD_NEK2_1 1699 1704 PF00069 0.313
MOD_NEK2_1 1735 1740 PF00069 0.384
MOD_NEK2_1 1828 1833 PF00069 0.252
MOD_NEK2_1 1867 1872 PF00069 0.343
MOD_NEK2_1 1924 1929 PF00069 0.522
MOD_NEK2_1 252 257 PF00069 0.399
MOD_NEK2_1 28 33 PF00069 0.351
MOD_NEK2_1 280 285 PF00069 0.593
MOD_NEK2_1 349 354 PF00069 0.307
MOD_NEK2_1 369 374 PF00069 0.304
MOD_NEK2_1 506 511 PF00069 0.301
MOD_NEK2_1 518 523 PF00069 0.421
MOD_NEK2_1 578 583 PF00069 0.252
MOD_NEK2_1 589 594 PF00069 0.237
MOD_NEK2_1 661 666 PF00069 0.368
MOD_NEK2_1 721 726 PF00069 0.379
MOD_NEK2_1 82 87 PF00069 0.392
MOD_NEK2_1 866 871 PF00069 0.410
MOD_NEK2_1 882 887 PF00069 0.213
MOD_NEK2_1 89 94 PF00069 0.312
MOD_NEK2_1 947 952 PF00069 0.262
MOD_NEK2_2 1176 1181 PF00069 0.222
MOD_NEK2_2 1508 1513 PF00069 0.448
MOD_NEK2_2 1620 1625 PF00069 0.435
MOD_NEK2_2 2001 2006 PF00069 0.430
MOD_OFUCOSY 1646 1651 PF10250 0.229
MOD_PIKK_1 1315 1321 PF00454 0.368
MOD_PIKK_1 1323 1329 PF00454 0.326
MOD_PIKK_1 1393 1399 PF00454 0.350
MOD_PIKK_1 1486 1492 PF00454 0.504
MOD_PIKK_1 149 155 PF00454 0.281
MOD_PIKK_1 36 42 PF00454 0.400
MOD_PIKK_1 667 673 PF00454 0.244
MOD_PIKK_1 725 731 PF00454 0.376
MOD_PIKK_1 787 793 PF00454 0.364
MOD_PIKK_1 826 832 PF00454 0.427
MOD_PIKK_1 856 862 PF00454 0.377
MOD_PK_1 706 712 PF00069 0.263
MOD_PKA_1 1462 1468 PF00069 0.332
MOD_PKA_1 1956 1962 PF00069 0.420
MOD_PKA_1 622 628 PF00069 0.257
MOD_PKA_2 1119 1125 PF00069 0.380
MOD_PKA_2 1162 1168 PF00069 0.194
MOD_PKA_2 128 134 PF00069 0.548
MOD_PKA_2 153 159 PF00069 0.473
MOD_PKA_2 1566 1572 PF00069 0.316
MOD_PKA_2 1699 1705 PF00069 0.316
MOD_PKA_2 1828 1834 PF00069 0.411
MOD_PKA_2 1867 1873 PF00069 0.365
MOD_PKA_2 1931 1937 PF00069 0.481
MOD_PKA_2 1967 1973 PF00069 0.736
MOD_PKA_2 212 218 PF00069 0.477
MOD_PKA_2 247 253 PF00069 0.656
MOD_PKA_2 441 447 PF00069 0.451
MOD_PKA_2 449 455 PF00069 0.426
MOD_PKA_2 571 577 PF00069 0.339
MOD_PKA_2 622 628 PF00069 0.257
MOD_PKA_2 76 82 PF00069 0.558
MOD_PKA_2 769 775 PF00069 0.249
MOD_PKA_2 875 881 PF00069 0.313
MOD_PKA_2 912 918 PF00069 0.365
MOD_PKA_2 940 946 PF00069 0.351
MOD_PKB_1 1845 1853 PF00069 0.314
MOD_PKB_1 1966 1974 PF00069 0.574
MOD_PKB_1 2012 2020 PF00069 0.465
MOD_Plk_1 1353 1359 PF00069 0.432
MOD_Plk_1 1434 1440 PF00069 0.354
MOD_Plk_1 18 24 PF00069 0.285
MOD_Plk_1 1924 1930 PF00069 0.352
MOD_Plk_1 1978 1984 PF00069 0.618
MOD_Plk_1 223 229 PF00069 0.305
MOD_Plk_1 280 286 PF00069 0.478
MOD_Plk_1 290 296 PF00069 0.424
MOD_Plk_1 5 11 PF00069 0.351
MOD_Plk_1 62 68 PF00069 0.376
MOD_Plk_2-3 1983 1989 PF00069 0.537
MOD_Plk_2-3 597 603 PF00069 0.262
MOD_Plk_4 1297 1303 PF00069 0.224
MOD_Plk_4 1415 1421 PF00069 0.295
MOD_Plk_4 1441 1447 PF00069 0.377
MOD_Plk_4 153 159 PF00069 0.445
MOD_Plk_4 1552 1558 PF00069 0.216
MOD_Plk_4 1687 1693 PF00069 0.316
MOD_Plk_4 1699 1705 PF00069 0.187
MOD_Plk_4 1739 1745 PF00069 0.337
MOD_Plk_4 1839 1845 PF00069 0.489
MOD_Plk_4 195 201 PF00069 0.429
MOD_Plk_4 322 328 PF00069 0.260
MOD_Plk_4 369 375 PF00069 0.249
MOD_Plk_4 459 465 PF00069 0.240
MOD_Plk_4 519 525 PF00069 0.426
MOD_Plk_4 578 584 PF00069 0.364
MOD_Plk_4 585 591 PF00069 0.289
MOD_Plk_4 606 612 PF00069 0.395
MOD_Plk_4 781 787 PF00069 0.224
MOD_Plk_4 832 838 PF00069 0.385
MOD_Plk_4 866 872 PF00069 0.292
MOD_Plk_4 875 881 PF00069 0.231
MOD_Plk_4 882 888 PF00069 0.217
MOD_Plk_4 940 946 PF00069 0.284
MOD_Plk_4 947 953 PF00069 0.249
MOD_Plk_4 981 987 PF00069 0.261
MOD_Plk_4 992 998 PF00069 0.237
MOD_ProDKin_1 1016 1022 PF00069 0.244
MOD_ProDKin_1 1207 1213 PF00069 0.393
MOD_ProDKin_1 1390 1396 PF00069 0.255
MOD_ProDKin_1 1537 1543 PF00069 0.531
MOD_ProDKin_1 1569 1575 PF00069 0.229
MOD_ProDKin_1 1737 1743 PF00069 0.244
MOD_ProDKin_1 1895 1901 PF00069 0.421
MOD_ProDKin_1 1932 1938 PF00069 0.442
MOD_ProDKin_1 1990 1996 PF00069 0.572
MOD_SUMO_for_1 1450 1453 PF00179 0.376
TRG_DiLeu_BaEn_1 1080 1085 PF01217 0.298
TRG_DiLeu_BaEn_1 542 547 PF01217 0.244
TRG_DiLeu_BaEn_4 73 79 PF01217 0.383
TRG_DiLeu_BaLyEn_6 1021 1026 PF01217 0.238
TRG_DiLeu_BaLyEn_6 1145 1150 PF01217 0.288
TRG_DiLeu_BaLyEn_6 1237 1242 PF01217 0.267
TRG_DiLeu_BaLyEn_6 1883 1888 PF01217 0.313
TRG_DiLeu_BaLyEn_6 33 38 PF01217 0.341
TRG_DiLeu_BaLyEn_6 943 948 PF01217 0.307
TRG_ENDOCYTIC_2 1013 1016 PF00928 0.262
TRG_ENDOCYTIC_2 1164 1167 PF00928 0.346
TRG_ENDOCYTIC_2 1294 1297 PF00928 0.229
TRG_ENDOCYTIC_2 1299 1302 PF00928 0.224
TRG_ENDOCYTIC_2 1306 1309 PF00928 0.236
TRG_ENDOCYTIC_2 1381 1384 PF00928 0.260
TRG_ENDOCYTIC_2 1692 1695 PF00928 0.316
TRG_ENDOCYTIC_2 502 505 PF00928 0.307
TRG_ENDOCYTIC_2 532 535 PF00928 0.331
TRG_ENDOCYTIC_2 802 805 PF00928 0.326
TRG_ER_diArg_1 1056 1058 PF00400 0.285
TRG_ER_diArg_1 1136 1138 PF00400 0.460
TRG_ER_diArg_1 1828 1830 PF00400 0.259
TRG_ER_diArg_1 1844 1847 PF00400 0.328
TRG_ER_diArg_1 1867 1869 PF00400 0.355
TRG_ER_diArg_1 1963 1966 PF00400 0.539
TRG_ER_diArg_1 2011 2014 PF00400 0.474
TRG_ER_diArg_1 210 213 PF00400 0.415
TRG_ER_diArg_1 266 269 PF00400 0.389
TRG_ER_diArg_1 284 287 PF00400 0.298
TRG_ER_diArg_1 543 546 PF00400 0.244
TRG_ER_diArg_1 621 623 PF00400 0.268
TRG_ER_diArg_1 873 876 PF00400 0.353
TRG_NES_CRM1_1 1076 1091 PF08389 0.246
TRG_NES_CRM1_1 1435 1448 PF08389 0.409
TRG_NES_CRM1_1 877 891 PF08389 0.187
TRG_NLS_MonoExtC_3 1963 1968 PF00514 0.544
TRG_NLS_MonoExtN_4 1963 1969 PF00514 0.559
TRG_Pf-PMV_PEXEL_1 1181 1185 PF00026 0.266
TRG_Pf-PMV_PEXEL_1 1726 1730 PF00026 0.212
TRG_Pf-PMV_PEXEL_1 1830 1835 PF00026 0.278
TRG_Pf-PMV_PEXEL_1 2003 2007 PF00026 0.419
TRG_Pf-PMV_PEXEL_1 36 40 PF00026 0.282
TRG_Pf-PMV_PEXEL_1 409 413 PF00026 0.240
TRG_Pf-PMV_PEXEL_1 688 693 PF00026 0.308

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HXJ0 Leptomonas seymouri 53% 100%
A0A1X0NNA8 Trypanosomatidae 34% 100%
A0A3Q8I9K3 Leishmania donovani 90% 100%
A0A3S5IRK1 Trypanosoma rangeli 35% 100%
A4HVG3 Leishmania infantum 90% 100%
D0A6U6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
E9AI44 Leishmania braziliensis 77% 100%
Q4QGB4 Leishmania major 89% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS