Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AP41_LEIMU

TriTrypDb:

LmxM.13.0070

Length:

196

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AP41

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AP41

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	104	106	PF00675	0.514
CLV_NRD_NRD_1	151	153	PF00675	0.504
CLV_NRD_NRD_1	75	77	PF00675	0.673
CLV_PCSK_FUR_1	73	77	PF00082	0.462
CLV_PCSK_KEX2_1	103	105	PF00082	0.560
CLV_PCSK_KEX2_1	151	153	PF00082	0.504
CLV_PCSK_KEX2_1	75	77	PF00082	0.673
CLV_PCSK_SKI1_1	137	141	PF00082	0.588
CLV_PCSK_SKI1_1	98	102	PF00082	0.518
DEG_Nend_UBRbox_2	1	3	PF02207	0.606
DOC_CKS1_1	68	73	PF01111	0.517
DOC_CYCLIN_RxL_1	92	106	PF00134	0.423
DOC_PP4_FxxP_1	186	189	PF00568	0.586
DOC_USP7_MATH_1	166	170	PF00917	0.542
DOC_USP7_MATH_1	38	42	PF00917	0.604
DOC_WW_Pin1_4	130	135	PF00397	0.608
DOC_WW_Pin1_4	185	190	PF00397	0.591
DOC_WW_Pin1_4	2	7	PF00397	0.645
DOC_WW_Pin1_4	49	54	PF00397	0.639
DOC_WW_Pin1_4	67	72	PF00397	0.552
DOC_WW_Pin1_4	8	13	PF00397	0.575
LIG_14-3-3_CanoR_1	103	112	PF00244	0.639
LIG_14-3-3_CanoR_1	75	82	PF00244	0.488
LIG_BRCT_BRCA1_1	182	186	PF00533	0.588
LIG_FHA_1	9	15	PF00498	0.469
LIG_FHA_2	32	38	PF00498	0.579
LIG_FHA_2	94	100	PF00498	0.551
LIG_LIR_Apic_2	183	189	PF02991	0.588
LIG_PDZ_Class_1	191	196	PF00595	0.621
LIG_Pex14_2	182	186	PF04695	0.539
LIG_SH2_STAT3	184	187	PF00017	0.539
LIG_SH2_STAT5	114	117	PF00017	0.622
LIG_SH2_STAT5	164	167	PF00017	0.530
LIG_SH3_3	65	71	PF00018	0.571
LIG_TRAF2_1	45	48	PF00917	0.515
LIG_TYR_ITIM	14	19	PF00017	0.439
MOD_CDK_SPK_2	49	54	PF00069	0.569
MOD_CDK_SPxK_1	67	73	PF00069	0.499
MOD_CDK_SPxxK_3	130	137	PF00069	0.605
MOD_CDK_SPxxK_3	2	9	PF00069	0.588
MOD_CK1_1	169	175	PF00069	0.545
MOD_CK1_1	180	186	PF00069	0.535
MOD_CK1_1	188	194	PF00069	0.538
MOD_CK1_1	8	14	PF00069	0.596
MOD_CK2_1	31	37	PF00069	0.536
MOD_CK2_1	93	99	PF00069	0.491
MOD_DYRK1A_RPxSP_1	67	71	PF00069	0.559
MOD_GlcNHglycan	190	193	PF01048	0.600
MOD_GlcNHglycan	77	80	PF01048	0.619
MOD_GSK3_1	160	167	PF00069	0.559
MOD_GSK3_1	169	176	PF00069	0.610
MOD_GSK3_1	188	195	PF00069	0.601
MOD_GSK3_1	43	50	PF00069	0.722
MOD_GSK3_1	63	70	PF00069	0.617
MOD_N-GLC_1	43	48	PF02516	0.631
MOD_NEK2_1	147	152	PF00069	0.450
MOD_NEK2_1	155	160	PF00069	0.483
MOD_NEK2_1	20	25	PF00069	0.549
MOD_NEK2_2	31	36	PF00069	0.518
MOD_PIKK_1	155	161	PF00454	0.392
MOD_PIKK_1	38	44	PF00454	0.536
MOD_PKA_1	103	109	PF00069	0.523
MOD_PKA_1	75	81	PF00069	0.649
MOD_PKA_2	103	109	PF00069	0.563
MOD_PKA_2	75	81	PF00069	0.649
MOD_PKB_1	73	81	PF00069	0.452
MOD_Plk_1	47	53	PF00069	0.575
MOD_ProDKin_1	130	136	PF00069	0.606
MOD_ProDKin_1	185	191	PF00069	0.593
MOD_ProDKin_1	2	8	PF00069	0.642
MOD_ProDKin_1	49	55	PF00069	0.635
MOD_ProDKin_1	67	73	PF00069	0.548
MOD_SUMO_rev_2	93	102	PF00179	0.561
TRG_ENDOCYTIC_2	16	19	PF00928	0.520
TRG_ENDOCYTIC_2	82	85	PF00928	0.431
TRG_ER_diArg_1	102	105	PF00400	0.536
TRG_ER_diArg_1	73	76	PF00400	0.511
TRG_Pf-PMV_PEXEL_1	120	124	PF00026	0.548

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0F4	Leptomonas seymouri	46%	92%
A0A3Q8IHV8	Leishmania donovani	91%	100%
A4HVE3	Leishmania infantum	91%	68%