Mcl1_mid domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

WD repeat and HMG-box DNA-binding protein, putative

Species:

Leishmania mexicana

UniProt:

E9AP22_LEIMU

TriTrypDb:

LmxM.12.1220

Length:

1410

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	8
GO:0043226	organelle	2	9
GO:0043227	membrane-bounded organelle	3	8
GO:0043229	intracellular organelle	3	9
GO:0043231	intracellular membrane-bounded organelle	4	8
GO:0110165	cellular anatomical entity	1	10
GO:0005657	replication fork	2	1
GO:0043596	nuclear replication fork	3	1

Expansion

Sequence features

E9AP22

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0000278	mitotic cell cycle	3	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006259	DNA metabolic process	4	1
GO:0006260	DNA replication	5	1
GO:0006261	DNA-templated DNA replication	6	1
GO:0006281	DNA repair	5	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0007049	cell cycle	2	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0033554	cellular response to stress	3	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0046483	heterocycle metabolic process	3	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003682	chromatin binding	2	1
GO:0005488	binding	1	2
GO:0003676	nucleic acid binding	3	1
GO:0003677	DNA binding	4	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	791	795	PF00656	0.312
CLV_C14_Caspase3-7	81	85	PF00656	0.399
CLV_NRD_NRD_1	110	112	PF00675	0.325
CLV_NRD_NRD_1	1101	1103	PF00675	0.516
CLV_NRD_NRD_1	1139	1141	PF00675	0.631
CLV_NRD_NRD_1	1385	1387	PF00675	0.519
CLV_NRD_NRD_1	354	356	PF00675	0.463
CLV_NRD_NRD_1	403	405	PF00675	0.631
CLV_NRD_NRD_1	406	408	PF00675	0.635
CLV_NRD_NRD_1	532	534	PF00675	0.654
CLV_NRD_NRD_1	743	745	PF00675	0.403
CLV_NRD_NRD_1	996	998	PF00675	0.481
CLV_PCSK_FUR_1	404	408	PF00082	0.465
CLV_PCSK_KEX2_1	109	111	PF00082	0.327
CLV_PCSK_KEX2_1	1101	1103	PF00082	0.516
CLV_PCSK_KEX2_1	1387	1389	PF00082	0.542
CLV_PCSK_KEX2_1	354	356	PF00082	0.486
CLV_PCSK_KEX2_1	403	405	PF00082	0.657
CLV_PCSK_KEX2_1	406	408	PF00082	0.666
CLV_PCSK_KEX2_1	496	498	PF00082	0.610
CLV_PCSK_KEX2_1	532	534	PF00082	0.654
CLV_PCSK_KEX2_1	914	916	PF00082	0.394
CLV_PCSK_KEX2_1	996	998	PF00082	0.477
CLV_PCSK_PC1ET2_1	1387	1389	PF00082	0.542
CLV_PCSK_PC1ET2_1	496	498	PF00082	0.582
CLV_PCSK_PC1ET2_1	914	916	PF00082	0.345
CLV_PCSK_PC1ET2_1	996	998	PF00082	0.454
CLV_PCSK_SKI1_1	1029	1033	PF00082	0.578
CLV_PCSK_SKI1_1	1108	1112	PF00082	0.457
CLV_PCSK_SKI1_1	1152	1156	PF00082	0.496
CLV_PCSK_SKI1_1	1197	1201	PF00082	0.627
CLV_PCSK_SKI1_1	187	191	PF00082	0.477
CLV_PCSK_SKI1_1	252	256	PF00082	0.448
CLV_PCSK_SKI1_1	362	366	PF00082	0.545
CLV_PCSK_SKI1_1	617	621	PF00082	0.403
CLV_PCSK_SKI1_1	689	693	PF00082	0.371
CLV_PCSK_SKI1_1	734	738	PF00082	0.347
CLV_PCSK_SKI1_1	75	79	PF00082	0.361
CLV_PCSK_SKI1_1	821	825	PF00082	0.322
CLV_PCSK_SKI1_1	963	967	PF00082	0.506
DEG_Nend_Nbox_1	1	3	PF02207	0.478
DEG_SCF_FBW7_1	1207	1213	PF00400	0.513
DEG_SCF_FBW7_2	1334	1341	PF00400	0.424
DEG_SCF_FBW7_2	592	599	PF00400	0.312
DEG_SPOP_SBC_1	1069	1073	PF00917	0.599
DEG_SPOP_SBC_1	1188	1192	PF00917	0.631
DEG_SPOP_SBC_1	1290	1294	PF00917	0.655
DEG_SPOP_SBC_1	1304	1308	PF00917	0.554
DEG_SPOP_SBC_1	739	743	PF00917	0.410
DOC_ANK_TNKS_1	241	248	PF00023	0.485
DOC_CDC14_PxL_1	1402	1410	PF14671	0.601
DOC_CKS1_1	1041	1046	PF01111	0.577
DOC_CKS1_1	1207	1212	PF01111	0.623
DOC_CKS1_1	678	683	PF01111	0.180
DOC_CYCLIN_RxL_1	976	988	PF00134	0.397
DOC_CYCLIN_yCln2_LP_2	136	142	PF00134	0.383
DOC_MAPK_gen_1	1011	1020	PF00069	0.418
DOC_MAPK_MEF2A_6	1011	1020	PF00069	0.330
DOC_MAPK_MEF2A_6	751	760	PF00069	0.317
DOC_MAPK_NFAT4_5	1013	1021	PF00069	0.335
DOC_PP1_RVXF_1	1100	1107	PF00149	0.523
DOC_PP2B_LxvP_1	1112	1115	PF13499	0.623
DOC_PP2B_LxvP_1	1277	1280	PF13499	0.430
DOC_PP2B_LxvP_1	136	139	PF13499	0.419
DOC_PP2B_LxvP_1	216	219	PF13499	0.390
DOC_PP2B_LxvP_1	238	241	PF13499	0.548
DOC_PP2B_LxvP_1	884	887	PF13499	0.358
DOC_USP7_MATH_1	1033	1037	PF00917	0.614
DOC_USP7_MATH_1	1095	1099	PF00917	0.477
DOC_USP7_MATH_1	1116	1120	PF00917	0.562
DOC_USP7_MATH_1	1136	1140	PF00917	0.680
DOC_USP7_MATH_1	1147	1151	PF00917	0.671
DOC_USP7_MATH_1	115	119	PF00917	0.349
DOC_USP7_MATH_1	1188	1192	PF00917	0.602
DOC_USP7_MATH_1	1211	1215	PF00917	0.662
DOC_USP7_MATH_1	1226	1230	PF00917	0.448
DOC_USP7_MATH_1	1231	1235	PF00917	0.549
DOC_USP7_MATH_1	1242	1246	PF00917	0.619
DOC_USP7_MATH_1	1264	1268	PF00917	0.687
DOC_USP7_MATH_1	1273	1277	PF00917	0.435
DOC_USP7_MATH_1	1289	1293	PF00917	0.564
DOC_USP7_MATH_1	1304	1308	PF00917	0.563
DOC_USP7_MATH_1	141	145	PF00917	0.385
DOC_USP7_MATH_1	155	159	PF00917	0.290
DOC_USP7_MATH_1	366	370	PF00917	0.707
DOC_USP7_MATH_1	443	447	PF00917	0.675
DOC_USP7_MATH_1	572	576	PF00917	0.641
DOC_USP7_MATH_1	606	610	PF00917	0.287
DOC_USP7_MATH_1	662	666	PF00917	0.427
DOC_USP7_MATH_1	777	781	PF00917	0.480
DOC_USP7_MATH_1	793	797	PF00917	0.220
DOC_USP7_MATH_1	872	876	PF00917	0.345
DOC_USP7_MATH_1	942	946	PF00917	0.526
DOC_USP7_UBL2_3	284	288	PF12436	0.518
DOC_USP7_UBL2_3	37	41	PF12436	0.385
DOC_USP7_UBL2_3	978	982	PF12436	0.438
DOC_USP7_UBL2_3	994	998	PF12436	0.425
DOC_WW_Pin1_4	1037	1042	PF00397	0.690
DOC_WW_Pin1_4	1061	1066	PF00397	0.704
DOC_WW_Pin1_4	1078	1083	PF00397	0.455
DOC_WW_Pin1_4	1206	1211	PF00397	0.655
DOC_WW_Pin1_4	1238	1243	PF00397	0.524
DOC_WW_Pin1_4	1252	1257	PF00397	0.591
DOC_WW_Pin1_4	1258	1263	PF00397	0.445
DOC_WW_Pin1_4	1271	1276	PF00397	0.594
DOC_WW_Pin1_4	1312	1317	PF00397	0.568
DOC_WW_Pin1_4	1334	1339	PF00397	0.566
DOC_WW_Pin1_4	1370	1375	PF00397	0.387
DOC_WW_Pin1_4	145	150	PF00397	0.302
DOC_WW_Pin1_4	169	174	PF00397	0.533
DOC_WW_Pin1_4	176	181	PF00397	0.478
DOC_WW_Pin1_4	188	193	PF00397	0.356
DOC_WW_Pin1_4	354	359	PF00397	0.683
DOC_WW_Pin1_4	592	597	PF00397	0.306
DOC_WW_Pin1_4	643	648	PF00397	0.323
DOC_WW_Pin1_4	666	671	PF00397	0.185
DOC_WW_Pin1_4	677	682	PF00397	0.383
DOC_WW_Pin1_4	780	785	PF00397	0.180
LIG_14-3-3_CanoR_1	1067	1077	PF00244	0.720
LIG_14-3-3_CanoR_1	1101	1107	PF00244	0.525
LIG_14-3-3_CanoR_1	1132	1136	PF00244	0.556
LIG_14-3-3_CanoR_1	1148	1152	PF00244	0.466
LIG_14-3-3_CanoR_1	1161	1166	PF00244	0.811
LIG_14-3-3_CanoR_1	1197	1202	PF00244	0.482
LIG_14-3-3_CanoR_1	1212	1216	PF00244	0.671
LIG_14-3-3_CanoR_1	1219	1225	PF00244	0.579
LIG_14-3-3_CanoR_1	1246	1252	PF00244	0.638
LIG_14-3-3_CanoR_1	1288	1298	PF00244	0.589
LIG_14-3-3_CanoR_1	203	207	PF00244	0.461
LIG_14-3-3_CanoR_1	232	241	PF00244	0.569
LIG_14-3-3_CanoR_1	252	261	PF00244	0.432
LIG_14-3-3_CanoR_1	299	308	PF00244	0.578
LIG_14-3-3_CanoR_1	349	353	PF00244	0.560
LIG_14-3-3_CanoR_1	671	675	PF00244	0.349
LIG_14-3-3_CanoR_1	717	722	PF00244	0.307
LIG_14-3-3_CanoR_1	734	739	PF00244	0.287
LIG_14-3-3_CanoR_1	744	754	PF00244	0.359
LIG_14-3-3_CanoR_1	778	784	PF00244	0.387
LIG_14-3-3_CanoR_1	915	920	PF00244	0.371
LIG_Actin_WH2_2	338	356	PF00022	0.568
LIG_AP2alpha_2	1324	1326	PF02296	0.552
LIG_APCC_ABBA_1	1323	1328	PF00400	0.547
LIG_BRCT_BRCA1_1	1294	1298	PF00533	0.566
LIG_BRCT_BRCA1_1	1377	1381	PF00533	0.492
LIG_CtBP_PxDLS_1	456	460	PF00389	0.454
LIG_DCNL_PONY_1	1	4	PF03556	0.382
LIG_deltaCOP1_diTrp_1	825	831	PF00928	0.403
LIG_DLG_GKlike_1	1377	1385	PF00625	0.472
LIG_DLG_GKlike_1	717	724	PF00625	0.334
LIG_EH_1	1143	1147	PF12763	0.613
LIG_eIF4E_1	835	841	PF01652	0.403
LIG_FHA_1	1061	1067	PF00498	0.775
LIG_FHA_1	1088	1094	PF00498	0.599
LIG_FHA_1	1123	1129	PF00498	0.765
LIG_FHA_1	1194	1200	PF00498	0.565
LIG_FHA_1	1218	1224	PF00498	0.688
LIG_FHA_1	1272	1278	PF00498	0.687
LIG_FHA_1	1294	1300	PF00498	0.476
LIG_FHA_1	131	137	PF00498	0.369
LIG_FHA_1	1313	1319	PF00498	0.606
LIG_FHA_1	1337	1343	PF00498	0.499
LIG_FHA_1	1370	1376	PF00498	0.625
LIG_FHA_1	180	186	PF00498	0.433
LIG_FHA_1	209	215	PF00498	0.406
LIG_FHA_1	324	330	PF00498	0.668
LIG_FHA_1	432	438	PF00498	0.605
LIG_FHA_1	763	769	PF00498	0.421
LIG_FHA_1	777	783	PF00498	0.309
LIG_FHA_1	795	801	PF00498	0.229
LIG_FHA_1	814	820	PF00498	0.287
LIG_FHA_1	877	883	PF00498	0.287
LIG_FHA_1	95	101	PF00498	0.333
LIG_FHA_2	1087	1093	PF00498	0.611
LIG_FHA_2	170	176	PF00498	0.549
LIG_FHA_2	218	224	PF00498	0.501
LIG_FHA_2	314	320	PF00498	0.591
LIG_FHA_2	515	521	PF00498	0.790
LIG_FHA_2	582	588	PF00498	0.419
LIG_FHA_2	837	843	PF00498	0.347
LIG_FHA_2	889	895	PF00498	0.398
LIG_GBD_Chelix_1	60	68	PF00786	0.419
LIG_HP1_1	141	145	PF01393	0.417
LIG_LIR_Gen_1	251	262	PF02991	0.463
LIG_LIR_Gen_1	621	632	PF02991	0.312
LIG_LIR_Gen_1	673	684	PF02991	0.305
LIG_LIR_Gen_1	712	721	PF02991	0.287
LIG_LIR_Gen_1	898	908	PF02991	0.377
LIG_LIR_LC3C_4	133	138	PF02991	0.423
LIG_LIR_Nem_3	1337	1343	PF02991	0.668
LIG_LIR_Nem_3	251	257	PF02991	0.463
LIG_LIR_Nem_3	602	607	PF02991	0.221
LIG_LIR_Nem_3	621	627	PF02991	0.466
LIG_LIR_Nem_3	673	679	PF02991	0.287
LIG_LIR_Nem_3	712	718	PF02991	0.287
LIG_LIR_Nem_3	753	757	PF02991	0.287
LIG_LIR_Nem_3	830	834	PF02991	0.287
LIG_LIR_Nem_3	898	903	PF02991	0.387
LIG_NRBOX	1016	1022	PF00104	0.476
LIG_OCRL_FandH_1	253	265	PF00620	0.453
LIG_PDZ_Class_2	1405	1410	PF00595	0.522
LIG_Pex14_1	831	835	PF04695	0.347
LIG_Pex14_2	675	679	PF04695	0.369
LIG_Pex14_2	750	754	PF04695	0.287
LIG_Pex14_2	823	827	PF04695	0.287
LIG_SH2_CRK	607	611	PF00017	0.287
LIG_SH2_NCK_1	607	611	PF00017	0.287
LIG_SH2_SRC	927	930	PF00017	0.445
LIG_SH2_STAP1	548	552	PF00017	0.469
LIG_SH2_STAP1	588	592	PF00017	0.287
LIG_SH2_STAP1	845	849	PF00017	0.403
LIG_SH2_STAP1	920	924	PF00017	0.443
LIG_SH2_STAP1	987	991	PF00017	0.568
LIG_SH2_STAT3	588	591	PF00017	0.287
LIG_SH2_STAT5	113	116	PF00017	0.431
LIG_SH2_STAT5	153	156	PF00017	0.442
LIG_SH2_STAT5	227	230	PF00017	0.560
LIG_SH2_STAT5	604	607	PF00017	0.287
LIG_SH2_STAT5	612	615	PF00017	0.287
LIG_SH2_STAT5	707	710	PF00017	0.301
LIG_SH2_STAT5	715	718	PF00017	0.262
LIG_SH3_1	864	870	PF00018	0.287
LIG_SH3_3	1038	1044	PF00018	0.603
LIG_SH3_3	1178	1184	PF00018	0.584
LIG_SH3_3	135	141	PF00018	0.304
LIG_SH3_3	186	192	PF00018	0.459
LIG_SH3_3	653	659	PF00018	0.438
LIG_SH3_3	675	681	PF00018	0.180
LIG_SH3_3	831	837	PF00018	0.301
LIG_SH3_3	864	870	PF00018	0.287
LIG_SUMO_SIM_anti_2	56	62	PF11976	0.331
LIG_SUMO_SIM_anti_2	725	730	PF11976	0.287
LIG_SUMO_SIM_anti_2	755	761	PF11976	0.403
LIG_SUMO_SIM_par_1	1043	1048	PF11976	0.572
LIG_SUMO_SIM_par_1	1356	1363	PF11976	0.501
LIG_SUMO_SIM_par_1	214	221	PF11976	0.502
LIG_SUMO_SIM_par_1	28	36	PF11976	0.417
LIG_SUMO_SIM_par_1	755	761	PF11976	0.344
LIG_SUMO_SIM_par_1	982	988	PF11976	0.404
LIG_TRAF2_1	386	389	PF00917	0.676
LIG_TRAF2_1	597	600	PF00917	0.403
LIG_TYR_ITIM	605	610	PF00017	0.287
LIG_TYR_ITIM	705	710	PF00017	0.312
LIG_UBA3_1	214	222	PF00899	0.278
LIG_WRC_WIRS_1	45	50	PF05994	0.410
LIG_WRC_WIRS_1	747	752	PF05994	0.287
LIG_WW_3	1209	1213	PF00397	0.665
MOD_CDC14_SPxK_1	1064	1067	PF00782	0.671
MOD_CDK_SPK_2	176	181	PF00069	0.417
MOD_CDK_SPK_2	354	359	PF00069	0.551
MOD_CDK_SPK_2	666	671	PF00069	0.199
MOD_CDK_SPK_2	780	785	PF00069	0.180
MOD_CDK_SPxK_1	1061	1067	PF00069	0.680
MOD_CDK_SPxK_1	1206	1212	PF00069	0.657
MOD_CDK_SPxxK_3	1370	1377	PF00069	0.389
MOD_CDK_SPxxK_3	188	195	PF00069	0.359
MOD_CK1_1	1075	1081	PF00069	0.616
MOD_CK1_1	1083	1089	PF00069	0.641
MOD_CK1_1	1117	1123	PF00069	0.647
MOD_CK1_1	1191	1197	PF00069	0.542
MOD_CK1_1	1245	1251	PF00069	0.624
MOD_CK1_1	1254	1260	PF00069	0.646
MOD_CK1_1	1271	1277	PF00069	0.691
MOD_CK1_1	1278	1284	PF00069	0.644
MOD_CK1_1	1292	1298	PF00069	0.444
MOD_CK1_1	1346	1352	PF00069	0.645
MOD_CK1_1	1360	1366	PF00069	0.617
MOD_CK1_1	188	194	PF00069	0.500
MOD_CK1_1	236	242	PF00069	0.625
MOD_CK1_1	303	309	PF00069	0.625
MOD_CK1_1	32	38	PF00069	0.408
MOD_CK1_1	323	329	PF00069	0.385
MOD_CK1_1	436	442	PF00069	0.650
MOD_CK1_1	446	452	PF00069	0.656
MOD_CK1_1	780	786	PF00069	0.404
MOD_CK1_1	875	881	PF00069	0.369
MOD_CK1_1	945	951	PF00069	0.466
MOD_CK2_1	1377	1383	PF00069	0.470
MOD_CK2_1	169	175	PF00069	0.574
MOD_CK2_1	217	223	PF00069	0.499
MOD_CK2_1	313	319	PF00069	0.656
MOD_CK2_1	381	387	PF00069	0.766
MOD_CK2_1	516	522	PF00069	0.750
MOD_CK2_1	662	668	PF00069	0.403
MOD_CK2_1	719	725	PF00069	0.323
MOD_CK2_1	888	894	PF00069	0.409
MOD_CMANNOS	802	805	PF00535	0.287
MOD_GlcNHglycan	1035	1038	PF01048	0.713
MOD_GlcNHglycan	1082	1085	PF01048	0.690
MOD_GlcNHglycan	1092	1096	PF01048	0.414
MOD_GlcNHglycan	1133	1136	PF01048	0.635
MOD_GlcNHglycan	1185	1188	PF01048	0.460
MOD_GlcNHglycan	1247	1250	PF01048	0.679
MOD_GlcNHglycan	1270	1273	PF01048	0.656
MOD_GlcNHglycan	1277	1280	PF01048	0.653
MOD_GlcNHglycan	1312	1315	PF01048	0.670
MOD_GlcNHglycan	1348	1351	PF01048	0.656
MOD_GlcNHglycan	157	160	PF01048	0.369
MOD_GlcNHglycan	238	241	PF01048	0.548
MOD_GlcNHglycan	309	312	PF01048	0.520
MOD_GlcNHglycan	321	325	PF01048	0.617
MOD_GlcNHglycan	368	371	PF01048	0.671
MOD_GlcNHglycan	438	441	PF01048	0.630
MOD_GlcNHglycan	451	454	PF01048	0.608
MOD_GlcNHglycan	529	532	PF01048	0.508
MOD_GlcNHglycan	538	541	PF01048	0.538
MOD_GlcNHglycan	568	571	PF01048	0.657
MOD_GlcNHglycan	721	724	PF01048	0.310
MOD_GlcNHglycan	779	782	PF01048	0.457
MOD_GlcNHglycan	84	87	PF01048	0.422
MOD_GlcNHglycan	874	877	PF01048	0.282
MOD_GlcNHglycan	920	923	PF01048	0.473
MOD_GlcNHglycan	940	943	PF01048	0.506
MOD_GSK3_1	1033	1040	PF00069	0.619
MOD_GSK3_1	1056	1063	PF00069	0.623
MOD_GSK3_1	1068	1075	PF00069	0.684
MOD_GSK3_1	1080	1087	PF00069	0.552
MOD_GSK3_1	1091	1098	PF00069	0.566
MOD_GSK3_1	1104	1111	PF00069	0.692
MOD_GSK3_1	1116	1123	PF00069	0.608
MOD_GSK3_1	1124	1131	PF00069	0.650
MOD_GSK3_1	1183	1190	PF00069	0.601
MOD_GSK3_1	1193	1200	PF00069	0.486
MOD_GSK3_1	1202	1209	PF00069	0.535
MOD_GSK3_1	1211	1218	PF00069	0.534
MOD_GSK3_1	1226	1233	PF00069	0.651
MOD_GSK3_1	1238	1245	PF00069	0.579
MOD_GSK3_1	1254	1261	PF00069	0.578
MOD_GSK3_1	1264	1271	PF00069	0.693
MOD_GSK3_1	1289	1296	PF00069	0.555
MOD_GSK3_1	1302	1309	PF00069	0.540
MOD_GSK3_1	1312	1319	PF00069	0.523
MOD_GSK3_1	1330	1337	PF00069	0.550
MOD_GSK3_1	1341	1348	PF00069	0.496
MOD_GSK3_1	141	148	PF00069	0.361
MOD_GSK3_1	165	172	PF00069	0.482
MOD_GSK3_1	286	293	PF00069	0.541
MOD_GSK3_1	29	36	PF00069	0.406
MOD_GSK3_1	299	306	PF00069	0.601
MOD_GSK3_1	362	369	PF00069	0.682
MOD_GSK3_1	427	434	PF00069	0.632
MOD_GSK3_1	438	445	PF00069	0.573
MOD_GSK3_1	613	620	PF00069	0.287
MOD_GSK3_1	662	669	PF00069	0.192
MOD_GSK3_1	734	741	PF00069	0.375
MOD_GSK3_1	758	765	PF00069	0.339
MOD_GSK3_1	776	783	PF00069	0.379
MOD_GSK3_1	78	85	PF00069	0.398
MOD_GSK3_1	872	879	PF00069	0.287
MOD_GSK3_1	914	921	PF00069	0.379
MOD_GSK3_1	938	945	PF00069	0.543
MOD_LATS_1	250	256	PF00433	0.356
MOD_N-GLC_1	1060	1065	PF02516	0.672
MOD_N-GLC_1	208	213	PF02516	0.243
MOD_N-GLC_1	233	238	PF02516	0.464
MOD_N-GLC_1	300	305	PF02516	0.586
MOD_N-GLC_1	395	400	PF02516	0.651
MOD_N-GLC_1	527	532	PF02516	0.520
MOD_N-GLC_2	411	413	PF02516	0.473
MOD_NEK2_1	1077	1082	PF00069	0.621
MOD_NEK2_1	1128	1133	PF00069	0.628
MOD_NEK2_1	1146	1151	PF00069	0.594
MOD_NEK2_1	1201	1206	PF00069	0.566
MOD_NEK2_1	1310	1315	PF00069	0.519
MOD_NEK2_1	1343	1348	PF00069	0.636
MOD_NEK2_1	290	295	PF00069	0.528
MOD_NEK2_1	33	38	PF00069	0.516
MOD_NEK2_1	636	641	PF00069	0.416
MOD_NEK2_1	66	71	PF00069	0.315
MOD_NEK2_1	719	724	PF00069	0.301
MOD_NEK2_1	729	734	PF00069	0.349
MOD_NEK2_1	738	743	PF00069	0.437
MOD_NEK2_1	746	751	PF00069	0.244
MOD_NEK2_1	78	83	PF00069	0.328
MOD_NEK2_1	888	893	PF00069	0.487
MOD_NEK2_1	938	943	PF00069	0.447
MOD_NEK2_1	970	975	PF00069	0.470
MOD_NEK2_1	989	994	PF00069	0.452
MOD_NEK2_2	1147	1152	PF00069	0.431
MOD_NEK2_2	115	120	PF00069	0.323
MOD_NEK2_2	1231	1236	PF00069	0.420
MOD_NEK2_2	29	34	PF00069	0.401
MOD_NEK2_2	395	400	PF00069	0.661
MOD_NEK2_2	44	49	PF00069	0.372
MOD_NEK2_2	670	675	PF00069	0.254
MOD_NEK2_2	694	699	PF00069	0.312
MOD_PIKK_1	1095	1101	PF00454	0.666
MOD_PIKK_1	1114	1120	PF00454	0.613
MOD_PIKK_1	1174	1180	PF00454	0.628
MOD_PIKK_1	1202	1208	PF00454	0.515
MOD_PIKK_1	122	128	PF00454	0.399
MOD_PIKK_1	179	185	PF00454	0.603
MOD_PIKK_1	265	271	PF00454	0.423
MOD_PIKK_1	729	735	PF00454	0.317
MOD_PIKK_1	942	948	PF00454	0.539
MOD_PKA_1	1056	1062	PF00069	0.455
MOD_PKA_1	914	920	PF00069	0.347
MOD_PKA_2	1131	1137	PF00069	0.642
MOD_PKA_2	1147	1153	PF00069	0.586
MOD_PKA_2	1160	1166	PF00069	0.750
MOD_PKA_2	1211	1217	PF00069	0.699
MOD_PKA_2	1218	1224	PF00069	0.594
MOD_PKA_2	1245	1251	PF00069	0.679
MOD_PKA_2	13	19	PF00069	0.502
MOD_PKA_2	202	208	PF00069	0.459
MOD_PKA_2	348	354	PF00069	0.548
MOD_PKA_2	402	408	PF00069	0.599
MOD_PKA_2	479	485	PF00069	0.571
MOD_PKA_2	636	642	PF00069	0.317
MOD_PKA_2	670	676	PF00069	0.349
MOD_PKA_2	777	783	PF00069	0.457
MOD_PKA_2	860	866	PF00069	0.347
MOD_PKA_2	914	920	PF00069	0.347
MOD_PKA_2	989	995	PF00069	0.356
MOD_PKB_1	501	509	PF00069	0.676
MOD_Plk_1	1027	1033	PF00069	0.494
MOD_Plk_1	1091	1097	PF00069	0.438
MOD_Plk_1	1108	1114	PF00069	0.432
MOD_Plk_1	196	202	PF00069	0.579
MOD_Plk_1	233	239	PF00069	0.467
MOD_Plk_1	395	401	PF00069	0.752
MOD_Plk_1	550	556	PF00069	0.715
MOD_Plk_1	586	592	PF00069	0.287
MOD_Plk_1	617	623	PF00069	0.317
MOD_Plk_1	841	847	PF00069	0.287
MOD_Plk_2-3	1336	1342	PF00069	0.427
MOD_Plk_2-3	381	387	PF00069	0.576
MOD_Plk_2-3	427	433	PF00069	0.576
MOD_Plk_2-3	469	475	PF00069	0.609
MOD_Plk_2-3	550	556	PF00069	0.660
MOD_Plk_2-3	836	842	PF00069	0.347
MOD_Plk_4	1124	1130	PF00069	0.467
MOD_Plk_4	1197	1203	PF00069	0.562
MOD_Plk_4	1231	1237	PF00069	0.456
MOD_Plk_4	1360	1366	PF00069	0.562
MOD_Plk_4	286	292	PF00069	0.313
MOD_Plk_4	29	35	PF00069	0.399
MOD_Plk_4	636	642	PF00069	0.306
MOD_Plk_4	670	676	PF00069	0.320
MOD_Plk_4	734	740	PF00069	0.335
MOD_Plk_4	827	833	PF00069	0.287
MOD_Plk_4	915	921	PF00069	0.373
MOD_ProDKin_1	1037	1043	PF00069	0.689
MOD_ProDKin_1	1061	1067	PF00069	0.700
MOD_ProDKin_1	1078	1084	PF00069	0.453
MOD_ProDKin_1	1206	1212	PF00069	0.657
MOD_ProDKin_1	1238	1244	PF00069	0.522
MOD_ProDKin_1	1252	1258	PF00069	0.591
MOD_ProDKin_1	1271	1277	PF00069	0.593
MOD_ProDKin_1	1312	1318	PF00069	0.565
MOD_ProDKin_1	1334	1340	PF00069	0.567
MOD_ProDKin_1	1370	1376	PF00069	0.388
MOD_ProDKin_1	145	151	PF00069	0.304
MOD_ProDKin_1	169	175	PF00069	0.531
MOD_ProDKin_1	176	182	PF00069	0.475
MOD_ProDKin_1	188	194	PF00069	0.351
MOD_ProDKin_1	354	360	PF00069	0.685
MOD_ProDKin_1	592	598	PF00069	0.306
MOD_ProDKin_1	643	649	PF00069	0.323
MOD_ProDKin_1	666	672	PF00069	0.185
MOD_ProDKin_1	677	683	PF00069	0.383
MOD_ProDKin_1	780	786	PF00069	0.180
MOD_SUMO_for_1	495	498	PF00179	0.586
MOD_SUMO_rev_2	383	392	PF00179	0.618
TRG_DiLeu_BaEn_1	953	958	PF01217	0.524
TRG_DiLeu_BaEn_4	559	565	PF01217	0.478
TRG_ENDOCYTIC_2	104	107	PF00928	0.264
TRG_ENDOCYTIC_2	153	156	PF00928	0.442
TRG_ENDOCYTIC_2	607	610	PF00928	0.287
TRG_ENDOCYTIC_2	676	679	PF00928	0.287
TRG_ENDOCYTIC_2	707	710	PF00928	0.301
TRG_ENDOCYTIC_2	715	718	PF00928	0.262
TRG_ENDOCYTIC_2	927	930	PF00928	0.375
TRG_ER_diArg_1	109	111	PF00400	0.302
TRG_ER_diArg_1	1385	1388	PF00400	0.525
TRG_ER_diArg_1	241	244	PF00400	0.571
TRG_ER_diArg_1	353	355	PF00400	0.481
TRG_ER_diArg_1	403	406	PF00400	0.464
TRG_ER_diArg_1	505	508	PF00400	0.691
TRG_NLS_MonoCore_2	1054	1059	PF00514	0.437
TRG_NLS_MonoExtC_3	1054	1060	PF00514	0.498
TRG_NLS_MonoExtC_3	1385	1390	PF00514	0.534
TRG_NLS_MonoExtN_4	994	1000	PF00514	0.458
TRG_Pf-PMV_PEXEL_1	101	106	PF00026	0.350
TRG_Pf-PMV_PEXEL_1	507	511	PF00026	0.699
TRG_Pf-PMV_PEXEL_1	75	80	PF00026	0.422
TRG_Pf-PMV_PEXEL_1	838	842	PF00026	0.347
TRG_Pf-PMV_PEXEL_1	91	95	PF00026	0.349

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I4W8	Leptomonas seymouri	56%	99%
A0A1X0NMD2	Trypanosomatidae	39%	95%
A0A3Q8I9G0	Leishmania donovani	88%	100%
A0A422NV28	Trypanosoma rangeli	40%	100%
A4H702	Leishmania braziliensis	75%	99%
E9AGH5	Leishmania infantum	88%	100%
Q4QGG7	Leishmania major	89%	100%
V5BF46	Trypanosoma cruzi	40%	100%