Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9ANY3_LEIMU

TriTrypDb:

LmxM.12.0550

Length:

499

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ANY3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANY3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	349	353	PF00656	0.538
CLV_C14_Caspase3-7	442	446	PF00656	0.490
CLV_C14_Caspase3-7	82	86	PF00656	0.541
CLV_NRD_NRD_1	119	121	PF00675	0.479
CLV_NRD_NRD_1	122	124	PF00675	0.463
CLV_NRD_NRD_1	156	158	PF00675	0.500
CLV_NRD_NRD_1	18	20	PF00675	0.460
CLV_PCSK_KEX2_1	119	121	PF00082	0.479
CLV_PCSK_KEX2_1	18	20	PF00082	0.460
CLV_PCSK_KEX2_1	491	493	PF00082	0.485
CLV_PCSK_PC1ET2_1	491	493	PF00082	0.485
CLV_PCSK_PC7_1	487	493	PF00082	0.470
CLV_PCSK_SKI1_1	119	123	PF00082	0.498
CLV_PCSK_SKI1_1	306	310	PF00082	0.530
CLV_PCSK_SKI1_1	464	468	PF00082	0.459
CLV_PCSK_SKI1_1	471	475	PF00082	0.425
CLV_Separin_Metazoa	413	417	PF03568	0.627
CLV_Separin_Metazoa	468	472	PF03568	0.469
DEG_APCC_KENBOX_2	270	274	PF00400	0.685
DEG_SCF_FBW7_1	166	173	PF00400	0.608
DEG_SPOP_SBC_1	170	174	PF00917	0.624
DEG_SPOP_SBC_1	368	372	PF00917	0.573
DEG_SPOP_SBC_1	440	444	PF00917	0.491
DOC_MAPK_FxFP_2	422	425	PF00069	0.635
DOC_MAPK_gen_1	145	153	PF00069	0.494
DOC_PP2B_LxvP_1	75	78	PF13499	0.507
DOC_PP4_FxxP_1	296	299	PF00568	0.658
DOC_PP4_FxxP_1	422	425	PF00568	0.635
DOC_PP4_MxPP_1	214	217	PF00568	0.535
DOC_USP7_MATH_1	170	174	PF00917	0.624
DOC_USP7_MATH_1	177	181	PF00917	0.579
DOC_USP7_MATH_1	189	193	PF00917	0.469
DOC_USP7_MATH_1	207	211	PF00917	0.527
DOC_USP7_MATH_1	232	236	PF00917	0.663
DOC_USP7_MATH_1	310	314	PF00917	0.638
DOC_USP7_MATH_1	334	338	PF00917	0.666
DOC_USP7_MATH_1	347	351	PF00917	0.561
DOC_USP7_MATH_1	369	373	PF00917	0.580
DOC_USP7_MATH_1	389	393	PF00917	0.571
DOC_USP7_MATH_1	78	82	PF00917	0.509
DOC_USP7_UBL2_3	143	147	PF12436	0.641
DOC_USP7_UBL2_3	271	275	PF12436	0.682
DOC_WW_Pin1_4	166	171	PF00397	0.603
DOC_WW_Pin1_4	212	217	PF00397	0.662
DOC_WW_Pin1_4	223	228	PF00397	0.568
DOC_WW_Pin1_4	233	238	PF00397	0.520
DOC_WW_Pin1_4	255	260	PF00397	0.664
DOC_WW_Pin1_4	277	282	PF00397	0.592
DOC_WW_Pin1_4	295	300	PF00397	0.600
DOC_WW_Pin1_4	364	369	PF00397	0.672
DOC_WW_Pin1_4	371	376	PF00397	0.699
LIG_14-3-3_CanoR_1	18	27	PF00244	0.593
LIG_14-3-3_CanoR_1	244	248	PF00244	0.662
LIG_14-3-3_CanoR_1	338	348	PF00244	0.663
LIG_AP2alpha_2	420	422	PF02296	0.623
LIG_BIR_III_4	358	362	PF00653	0.553
LIG_BRCT_BRCA1_1	171	175	PF00533	0.628
LIG_CSL_BTD_1	318	321	PF09270	0.634
LIG_EVH1_1	424	428	PF00568	0.634
LIG_FHA_1	135	141	PF00498	0.488
LIG_FHA_1	278	284	PF00498	0.556
LIG_FHA_1	368	374	PF00498	0.587
LIG_FHA_1	385	391	PF00498	0.585
LIG_FHA_2	112	118	PF00498	0.477
LIG_FHA_2	20	26	PF00498	0.316
LIG_FHA_2	447	453	PF00498	0.611
LIG_GBD_Chelix_1	433	441	PF00786	0.509
LIG_LIR_Apic_2	226	231	PF02991	0.641
LIG_LIR_Apic_2	295	299	PF02991	0.658
LIG_LIR_Apic_2	420	425	PF02991	0.629
LIG_LIR_Gen_1	25	34	PF02991	0.322
LIG_LIR_Gen_1	9	17	PF02991	0.451
LIG_LIR_Nem_3	25	30	PF02991	0.458
LIG_LIR_Nem_3	488	493	PF02991	0.473
LIG_MYND_1	74	78	PF01753	0.506
LIG_RPA_C_Fungi	333	345	PF08784	0.538
LIG_SH2_CRK	222	226	PF00017	0.658
LIG_SH2_CRK	228	232	PF00017	0.599
LIG_SH2_CRK	490	494	PF00017	0.475
LIG_SH2_SRC	260	263	PF00017	0.540
LIG_SH2_STAP1	27	31	PF00017	0.444
LIG_SH2_STAP1	385	389	PF00017	0.641
LIG_SH2_STAT3	52	55	PF00017	0.362
LIG_SH2_STAT5	21	24	PF00017	0.315
LIG_SH2_STAT5	385	388	PF00017	0.646
LIG_SH3_1	363	369	PF00018	0.547
LIG_SH3_2	224	229	PF14604	0.553
LIG_SH3_3	221	227	PF00018	0.673
LIG_SH3_3	231	237	PF00018	0.675
LIG_SH3_3	253	259	PF00018	0.665
LIG_SH3_3	314	320	PF00018	0.633
LIG_SH3_3	363	369	PF00018	0.659
LIG_SH3_3	422	428	PF00018	0.688
LIG_SH3_CIN85_PxpxPR_1	421	426	PF14604	0.634
LIG_TRAF2_1	102	105	PF00917	0.531
LIG_TRAF2_1	259	262	PF00917	0.538
MOD_CDC14_SPxK_1	226	229	PF00782	0.548
MOD_CDK_SPxK_1	223	229	PF00069	0.554
MOD_CDK_SPxxK_3	299	306	PF00069	0.654
MOD_CK1_1	168	174	PF00069	0.617
MOD_CK1_1	209	215	PF00069	0.645
MOD_CK1_1	235	241	PF00069	0.658
MOD_CK1_1	246	252	PF00069	0.575
MOD_CK1_1	277	283	PF00069	0.622
MOD_CK1_1	286	292	PF00069	0.610
MOD_CK1_1	295	301	PF00069	0.573
MOD_CK1_1	3	9	PF00069	0.511
MOD_CK1_1	336	342	PF00069	0.642
MOD_CK1_1	350	356	PF00069	0.534
MOD_CK1_1	367	373	PF00069	0.626
MOD_CK1_1	439	445	PF00069	0.524
MOD_CK2_1	111	117	PF00069	0.475
MOD_CK2_1	19	25	PF00069	0.317
MOD_CK2_1	233	239	PF00069	0.665
MOD_CK2_1	255	261	PF00069	0.663
MOD_CK2_1	3	9	PF00069	0.511
MOD_CK2_1	343	349	PF00069	0.537
MOD_GlcNHglycan	125	129	PF01048	0.487
MOD_GlcNHglycan	179	182	PF01048	0.601
MOD_GlcNHglycan	209	212	PF01048	0.689
MOD_GlcNHglycan	276	280	PF01048	0.551
MOD_GlcNHglycan	312	315	PF01048	0.577
MOD_GlcNHglycan	345	348	PF01048	0.579
MOD_GlcNHglycan	349	352	PF01048	0.550
MOD_GlcNHglycan	380	383	PF01048	0.594
MOD_GlcNHglycan	387	390	PF01048	0.630
MOD_GlcNHglycan	429	432	PF01048	0.624
MOD_GlcNHglycan	452	456	PF01048	0.608
MOD_GlcNHglycan	71	74	PF01048	0.572
MOD_GlcNHglycan	91	94	PF01048	0.502
MOD_GSK3_1	107	114	PF00069	0.489
MOD_GSK3_1	164	171	PF00069	0.590
MOD_GSK3_1	177	184	PF00069	0.580
MOD_GSK3_1	242	249	PF00069	0.663
MOD_GSK3_1	288	295	PF00069	0.654
MOD_GSK3_1	334	341	PF00069	0.614
MOD_GSK3_1	343	350	PF00069	0.542
MOD_GSK3_1	364	371	PF00069	0.674
MOD_GSK3_1	385	392	PF00069	0.656
MOD_GSK3_1	436	443	PF00069	0.617
MOD_GSK3_1	65	72	PF00069	0.426
MOD_GSK3_1	84	91	PF00069	0.583
MOD_NEK2_1	107	112	PF00069	0.349
MOD_NEK2_1	164	169	PF00069	0.482
MOD_NEK2_1	243	248	PF00069	0.663
MOD_NEK2_1	89	94	PF00069	0.587
MOD_PIKK_1	215	221	PF00454	0.553
MOD_PIKK_1	336	342	PF00454	0.661
MOD_PIKK_1	391	397	PF00454	0.696
MOD_PKA_2	107	113	PF00069	0.403
MOD_PKA_2	134	140	PF00069	0.491
MOD_PKA_2	243	249	PF00069	0.662
MOD_PKA_2	398	404	PF00069	0.660
MOD_PKA_2	78	84	PF00069	0.627
MOD_PKA_2	96	102	PF00069	0.460
MOD_Plk_1	3	9	PF00069	0.511
MOD_Plk_1	59	65	PF00069	0.388
MOD_Plk_4	292	298	PF00069	0.659
MOD_Plk_4	398	404	PF00069	0.530
MOD_Plk_4	436	442	PF00069	0.618
MOD_ProDKin_1	166	172	PF00069	0.608
MOD_ProDKin_1	212	218	PF00069	0.663
MOD_ProDKin_1	223	229	PF00069	0.568
MOD_ProDKin_1	233	239	PF00069	0.522
MOD_ProDKin_1	255	261	PF00069	0.663
MOD_ProDKin_1	277	283	PF00069	0.594
MOD_ProDKin_1	295	301	PF00069	0.602
MOD_ProDKin_1	364	370	PF00069	0.672
MOD_ProDKin_1	371	377	PF00069	0.698
TRG_DiLeu_BaLyEn_6	71	76	PF01217	0.485
TRG_ENDOCYTIC_2	21	24	PF00928	0.442
TRG_ENDOCYTIC_2	27	30	PF00928	0.405
TRG_ENDOCYTIC_2	490	493	PF00928	0.476
TRG_ER_diArg_1	118	120	PF00400	0.480
TRG_ER_diArg_1	17	19	PF00400	0.464
TRG_Pf-PMV_PEXEL_1	120	125	PF00026	0.504
TRG_Pf-PMV_PEXEL_1	491	495	PF00026	0.358

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WS06	Leishmania donovani	85%	100%
E9AGE3	Leishmania infantum	84%	100%
Q4QGN7	Leishmania major	83%	100%