Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Present in the outer mitochondrial membrane proteome 18

Species:

Leishmania mexicana

UniProt:

E9ANY2_LEIMU

TriTrypDb:

LmxM.12.0540

Length:

167

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0005741	mitochondrial outer membrane	5	1
GO:0016020	membrane	2	1
GO:0019867	outer membrane	3	1
GO:0031090	organelle membrane	3	1
GO:0031966	mitochondrial membrane	4	1
GO:0031968	organelle outer membrane	4	1
GO:0098588	bounding membrane of organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9ANY2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANY2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	144	146	PF00675	0.780
CLV_NRD_NRD_1	2	4	PF00675	0.526
CLV_PCSK_KEX2_1	133	135	PF00082	0.751
CLV_PCSK_KEX2_1	2	4	PF00082	0.526
CLV_PCSK_PC1ET2_1	133	135	PF00082	0.751
CLV_PCSK_SKI1_1	7	11	PF00082	0.694
DEG_Nend_UBRbox_1	1	4	PF02207	0.483
DOC_PP1_RVXF_1	100	107	PF00149	0.674
DOC_PP1_RVXF_1	78	85	PF00149	0.617
DOC_USP7_UBL2_3	153	157	PF12436	0.684
DOC_WW_Pin1_4	106	111	PF00397	0.761
DOC_WW_Pin1_4	121	126	PF00397	0.524
DOC_WW_Pin1_4	148	153	PF00397	0.760
LIG_14-3-3_CanoR_1	143	152	PF00244	0.671
LIG_14-3-3_CanoR_1	7	17	PF00244	0.661
LIG_BIR_III_4	24	28	PF00653	0.608
LIG_BRCT_BRCA1_1	17	21	PF00533	0.752
LIG_LIR_Gen_1	155	165	PF02991	0.762
LIG_LIR_Nem_3	155	161	PF02991	0.769
LIG_NRP_CendR_1	164	167	PF00754	0.653
LIG_Pex14_2	17	21	PF04695	0.653
LIG_Pex14_2	9	13	PF04695	0.646
LIG_SH3_3	115	121	PF00018	0.694
LIG_SH3_3	146	152	PF00018	0.649
LIG_SH3_3	156	162	PF00018	0.688
LIG_SH3_3	67	73	PF00018	0.708
LIG_WRC_WIRS_1	10	15	PF05994	0.644
LIG_WW_1	162	165	PF00397	0.750
LIG_WW_3	161	165	PF00397	0.730
MOD_CDK_SPK_2	148	153	PF00069	0.760
MOD_CK1_1	11	17	PF00069	0.746
MOD_CK1_1	35	41	PF00069	0.701
MOD_Cter_Amidation	131	134	PF01082	0.751
MOD_GlcNHglycan	28	31	PF01048	0.721
MOD_GlcNHglycan	35	38	PF01048	0.775
MOD_GlcNHglycan	50	53	PF01048	0.645
MOD_GlcNHglycan	65	68	PF01048	0.544
MOD_GSK3_1	11	18	PF00069	0.658
MOD_GSK3_1	144	151	PF00069	0.771
MOD_GSK3_1	35	42	PF00069	0.757
MOD_NEK2_1	1	6	PF00069	0.655
MOD_NEK2_1	144	149	PF00069	0.677
MOD_NEK2_1	32	37	PF00069	0.784
MOD_NEK2_1	9	14	PF00069	0.642
MOD_NEK2_2	39	44	PF00069	0.782
MOD_PIKK_1	144	150	PF00454	0.675
MOD_PKA_2	1	7	PF00069	0.499
MOD_PKA_2	144	150	PF00069	0.675
MOD_Plk_4	39	45	PF00069	0.766
MOD_ProDKin_1	106	112	PF00069	0.760
MOD_ProDKin_1	121	127	PF00069	0.521
MOD_ProDKin_1	148	154	PF00069	0.760
MOD_SUMO_for_1	152	155	PF00179	0.757
MOD_SUMO_rev_2	151	159	PF00179	0.758
TRG_ER_diArg_1	1	3	PF00400	0.530

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4JMJ7	Bodo saltans	48%	100%
A0A3S7WRX5	Leishmania donovani	92%	100%
E9AGE2	Leishmania infantum	92%	100%
Q4QGN8	Leishmania major	92%	100%