Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9ANX6_LEIMU

TriTrypDb:

LmxM.12.0480

Length:

607

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ANX6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANX6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	589	593	PF00656	0.635
CLV_NRD_NRD_1	216	218	PF00675	0.640
CLV_NRD_NRD_1	246	248	PF00675	0.531
CLV_NRD_NRD_1	393	395	PF00675	0.695
CLV_PCSK_FUR_1	391	395	PF00082	0.634
CLV_PCSK_KEX2_1	216	218	PF00082	0.707
CLV_PCSK_KEX2_1	246	248	PF00082	0.531
CLV_PCSK_KEX2_1	390	392	PF00082	0.674
CLV_PCSK_KEX2_1	393	395	PF00082	0.667
CLV_PCSK_PC1ET2_1	390	392	PF00082	0.627
CLV_PCSK_SKI1_1	303	307	PF00082	0.527
CLV_PCSK_SKI1_1	387	391	PF00082	0.534
CLV_PCSK_SKI1_1	67	71	PF00082	0.520
DOC_CYCLIN_yCln2_LP_2	441	447	PF00134	0.518
DOC_MAPK_MEF2A_6	551	559	PF00069	0.488
DOC_PP1_RVXF_1	348	354	PF00149	0.622
DOC_USP7_MATH_1	134	138	PF00917	0.566
DOC_USP7_MATH_1	151	155	PF00917	0.682
DOC_USP7_MATH_1	16	20	PF00917	0.675
DOC_USP7_MATH_1	164	168	PF00917	0.561
DOC_USP7_MATH_1	240	244	PF00917	0.652
DOC_USP7_MATH_1	284	288	PF00917	0.819
DOC_USP7_MATH_1	40	44	PF00917	0.720
DOC_USP7_MATH_1	549	553	PF00917	0.673
DOC_USP7_MATH_1	581	585	PF00917	0.744
DOC_USP7_MATH_1	72	76	PF00917	0.657
DOC_WW_Pin1_4	194	199	PF00397	0.704
DOC_WW_Pin1_4	23	28	PF00397	0.669
DOC_WW_Pin1_4	36	41	PF00397	0.717
DOC_WW_Pin1_4	509	514	PF00397	0.568
DOC_WW_Pin1_4	89	94	PF00397	0.591
LIG_14-3-3_CanoR_1	216	222	PF00244	0.700
LIG_14-3-3_CanoR_1	230	240	PF00244	0.548
LIG_14-3-3_CanoR_1	303	310	PF00244	0.549
LIG_14-3-3_CanoR_1	393	401	PF00244	0.699
LIG_14-3-3_CanoR_1	519	524	PF00244	0.705
LIG_Actin_WH2_2	214	232	PF00022	0.521
LIG_BIR_III_4	426	430	PF00653	0.586
LIG_BRCT_BRCA1_1	205	209	PF00533	0.693
LIG_BRCT_BRCA1_1	214	218	PF00533	0.599
LIG_BRCT_BRCA1_1	46	50	PF00533	0.733
LIG_Dynein_DLC8_1	228	234	PF01221	0.505
LIG_FHA_1	118	124	PF00498	0.625
LIG_FHA_1	144	150	PF00498	0.605
LIG_FHA_1	396	402	PF00498	0.539
LIG_FHA_1	419	425	PF00498	0.674
LIG_FHA_1	481	487	PF00498	0.587
LIG_FHA_1	515	521	PF00498	0.529
LIG_FHA_1	571	577	PF00498	0.555
LIG_FHA_1	80	86	PF00498	0.723
LIG_FHA_2	401	407	PF00498	0.562
LIG_FHA_2	449	455	PF00498	0.721
LIG_FHA_2	570	576	PF00498	0.718
LIG_FHA_2	98	104	PF00498	0.528
LIG_LIR_Apic_2	234	240	PF02991	0.643
LIG_LIR_Apic_2	379	384	PF02991	0.627
LIG_LIR_Gen_1	103	112	PF02991	0.591
LIG_LIR_Gen_1	215	225	PF02991	0.532
LIG_LIR_Gen_1	332	341	PF02991	0.630
LIG_LIR_Nem_3	103	109	PF02991	0.595
LIG_LIR_Nem_3	215	221	PF02991	0.534
LIG_LIR_Nem_3	332	336	PF02991	0.632
LIG_Pex14_2	205	209	PF04695	0.539
LIG_SH2_CRK	381	385	PF00017	0.622
LIG_SH2_CRK	521	525	PF00017	0.511
LIG_SH2_SRC	453	456	PF00017	0.595
LIG_SH2_STAT5	237	240	PF00017	0.663
LIG_SH2_STAT5	381	384	PF00017	0.619
LIG_SH3_3	192	198	PF00018	0.670
LIG_SH3_3	21	27	PF00018	0.671
LIG_SH3_3	325	331	PF00018	0.635
LIG_SH3_3	336	342	PF00018	0.567
LIG_SH3_3	582	588	PF00018	0.651
LIG_SUMO_SIM_par_1	402	408	PF11976	0.506
LIG_SUMO_SIM_par_1	571	577	PF11976	0.664
LIG_TRAF2_1	262	265	PF00917	0.522
LIG_TRAF2_1	594	597	PF00917	0.603
LIG_WRC_WIRS_1	109	114	PF05994	0.665
MOD_CK1_1	223	229	PF00069	0.611
MOD_CK1_1	25	31	PF00069	0.654
MOD_CK1_1	312	318	PF00069	0.741
MOD_CK1_1	395	401	PF00069	0.507
MOD_CK1_1	412	418	PF00069	0.492
MOD_CK1_1	467	473	PF00069	0.668
MOD_CK1_1	48	54	PF00069	0.734
MOD_CK1_1	511	517	PF00069	0.669
MOD_CK1_1	541	547	PF00069	0.685
MOD_CK1_1	55	61	PF00069	0.670
MOD_CK1_1	566	572	PF00069	0.653
MOD_CK1_1	580	586	PF00069	0.612
MOD_CK1_1	79	85	PF00069	0.744
MOD_CK1_1	88	94	PF00069	0.678
MOD_CK2_1	16	22	PF00069	0.729
MOD_CK2_1	396	402	PF00069	0.710
MOD_CK2_1	562	568	PF00069	0.716
MOD_CK2_1	590	596	PF00069	0.614
MOD_CK2_1	97	103	PF00069	0.532
MOD_Cter_Amidation	244	247	PF01082	0.520
MOD_GlcNHglycan	114	117	PF01048	0.668
MOD_GlcNHglycan	153	156	PF01048	0.712
MOD_GlcNHglycan	166	169	PF01048	0.606
MOD_GlcNHglycan	171	175	PF01048	0.599
MOD_GlcNHglycan	18	21	PF01048	0.654
MOD_GlcNHglycan	205	208	PF01048	0.742
MOD_GlcNHglycan	209	212	PF01048	0.699
MOD_GlcNHglycan	222	225	PF01048	0.521
MOD_GlcNHglycan	242	245	PF01048	0.782
MOD_GlcNHglycan	251	254	PF01048	0.692
MOD_GlcNHglycan	285	289	PF01048	0.617
MOD_GlcNHglycan	3	6	PF01048	0.583
MOD_GlcNHglycan	410	414	PF01048	0.581
MOD_GlcNHglycan	47	50	PF01048	0.713
MOD_GlcNHglycan	471	474	PF01048	0.665
MOD_GlcNHglycan	521	524	PF01048	0.688
MOD_GlcNHglycan	535	538	PF01048	0.559
MOD_GlcNHglycan	568	571	PF01048	0.716
MOD_GlcNHglycan	57	60	PF01048	0.584
MOD_GlcNHglycan	579	582	PF01048	0.583
MOD_GlcNHglycan	592	595	PF01048	0.532
MOD_GlcNHglycan	76	81	PF01048	0.515
MOD_GlcNHglycan	87	90	PF01048	0.566
MOD_GSK3_1	108	115	PF00069	0.663
MOD_GSK3_1	134	141	PF00069	0.785
MOD_GSK3_1	153	160	PF00069	0.685
MOD_GSK3_1	199	206	PF00069	0.687
MOD_GSK3_1	207	214	PF00069	0.652
MOD_GSK3_1	284	291	PF00069	0.731
MOD_GSK3_1	292	299	PF00069	0.760
MOD_GSK3_1	305	312	PF00069	0.745
MOD_GSK3_1	36	43	PF00069	0.759
MOD_GSK3_1	392	399	PF00069	0.705
MOD_GSK3_1	414	421	PF00069	0.613
MOD_GSK3_1	44	51	PF00069	0.647
MOD_GSK3_1	476	483	PF00069	0.622
MOD_GSK3_1	505	512	PF00069	0.705
MOD_GSK3_1	538	545	PF00069	0.639
MOD_GSK3_1	549	556	PF00069	0.602
MOD_GSK3_1	562	569	PF00069	0.655
MOD_GSK3_1	576	583	PF00069	0.544
MOD_GSK3_1	586	593	PF00069	0.572
MOD_GSK3_1	72	79	PF00069	0.715
MOD_GSK3_1	85	92	PF00069	0.588
MOD_GSK3_1	97	104	PF00069	0.659
MOD_N-GLC_1	112	117	PF02516	0.723
MOD_N-GLC_1	312	317	PF02516	0.656
MOD_N-GLC_1	89	94	PF02516	0.518
MOD_NEK2_1	112	117	PF00069	0.523
MOD_NEK2_1	199	204	PF00069	0.582
MOD_NEK2_1	205	210	PF00069	0.583
MOD_NEK2_1	229	234	PF00069	0.756
MOD_NEK2_1	396	401	PF00069	0.708
MOD_NEK2_1	44	49	PF00069	0.780
MOD_NEK2_1	50	55	PF00069	0.731
MOD_NEK2_1	542	547	PF00069	0.691
MOD_NEK2_1	576	581	PF00069	0.571
MOD_NEK2_1	85	90	PF00069	0.613
MOD_NEK2_1	94	99	PF00069	0.721
MOD_NEK2_2	134	139	PF00069	0.574
MOD_NEK2_2	448	453	PF00069	0.588
MOD_OFUCOSY	482	488	PF10250	0.635
MOD_PIKK_1	229	235	PF00454	0.784
MOD_PIKK_1	292	298	PF00454	0.737
MOD_PKA_2	143	149	PF00069	0.667
MOD_PKA_2	157	163	PF00069	0.521
MOD_PKA_2	229	235	PF00069	0.574
MOD_PKA_2	296	302	PF00069	0.573
MOD_PKA_2	392	398	PF00069	0.696
MOD_PKA_2	9	15	PF00069	0.613
MOD_Plk_1	102	108	PF00069	0.631
MOD_Plk_1	263	269	PF00069	0.544
MOD_Plk_1	418	424	PF00069	0.666
MOD_Plk_1	570	576	PF00069	0.662
MOD_Plk_1	76	82	PF00069	0.509
MOD_Plk_2-3	586	592	PF00069	0.555
MOD_Plk_4	102	108	PF00069	0.754
MOD_Plk_4	114	120	PF00069	0.621
MOD_Plk_4	157	163	PF00069	0.658
MOD_Plk_4	400	406	PF00069	0.505
MOD_Plk_4	418	424	PF00069	0.487
MOD_Plk_4	437	443	PF00069	0.525
MOD_Plk_4	448	454	PF00069	0.574
MOD_Plk_4	494	500	PF00069	0.451
MOD_Plk_4	553	559	PF00069	0.697
MOD_ProDKin_1	194	200	PF00069	0.705
MOD_ProDKin_1	23	29	PF00069	0.670
MOD_ProDKin_1	36	42	PF00069	0.715
MOD_ProDKin_1	509	515	PF00069	0.566
MOD_ProDKin_1	89	95	PF00069	0.594
MOD_SUMO_for_1	389	392	PF00179	0.617
MOD_SUMO_rev_2	25	34	PF00179	0.685
TRG_DiLeu_BaEn_1	437	442	PF01217	0.523
TRG_ER_diArg_1	142	145	PF00400	0.506
TRG_ER_diArg_1	216	218	PF00400	0.532

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WRY4	Leishmania donovani	79%	100%
A4H6W9	Leishmania braziliensis	50%	100%
E9AGD6	Leishmania infantum	78%	100%
Q4QGP4	Leishmania major	74%	100%