Kinetoplastid kinetochore protein 6

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplastid kinetochore protein 6, putative

Species:

Leishmania mexicana

UniProt:

E9ANT5_LEIMU

TriTrypDb:

LmxM.12.0080

Length:

205

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ANT5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANT5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	147	151	PF00082	0.494
DEG_Nend_UBRbox_3	1	3	PF02207	0.549
DOC_MAPK_gen_1	116	125	PF00069	0.282
DOC_PP2B_LxvP_1	60	63	PF13499	0.634
DOC_USP7_MATH_1	137	141	PF00917	0.502
DOC_USP7_MATH_1	33	37	PF00917	0.571
LIG_14-3-3_CanoR_1	105	114	PF00244	0.422
LIG_14-3-3_CanoR_1	127	132	PF00244	0.563
LIG_14-3-3_CanoR_1	86	90	PF00244	0.606
LIG_deltaCOP1_diTrp_1	70	80	PF00928	0.470
LIG_FHA_1	120	126	PF00498	0.422
LIG_FHA_1	66	72	PF00498	0.550
LIG_FHA_2	72	78	PF00498	0.479
LIG_FHA_2	86	92	PF00498	0.441
LIG_LIR_Gen_1	31	42	PF02991	0.647
LIG_LIR_LC3C_4	39	44	PF02991	0.606
LIG_LIR_Nem_3	126	131	PF02991	0.357
LIG_LIR_Nem_3	31	37	PF02991	0.646
LIG_SH2_CRK	151	155	PF00017	0.444
LIG_SH2_PTP2	34	37	PF00017	0.652
LIG_SH2_STAT3	104	107	PF00017	0.593
LIG_SH2_STAT5	34	37	PF00017	0.652
LIG_SH2_STAT5	7	10	PF00017	0.509
LIG_SH3_3	34	40	PF00018	0.576
LIG_SUMO_SIM_anti_2	189	197	PF11976	0.493
LIG_SUMO_SIM_par_1	121	126	PF11976	0.319
LIG_UBA3_1	171	175	PF00899	0.541
LIG_UBA3_1	195	202	PF00899	0.556
MOD_CK1_1	65	71	PF00069	0.579
MOD_CK2_1	161	167	PF00069	0.427
MOD_CK2_1	69	75	PF00069	0.497
MOD_CK2_1	85	91	PF00069	0.469
MOD_GlcNHglycan	26	29	PF01048	0.577
MOD_GSK3_1	194	201	PF00069	0.559
MOD_GSK3_1	24	31	PF00069	0.539
MOD_GSK3_1	65	72	PF00069	0.547
MOD_N-GLC_1	137	142	PF02516	0.497
MOD_NEK2_1	161	166	PF00069	0.423
MOD_NEK2_2	33	38	PF00069	0.512
MOD_PIKK_1	129	135	PF00454	0.572
MOD_PKA_2	85	91	PF00069	0.507
MOD_Plk_1	110	116	PF00069	0.429
MOD_Plk_1	161	167	PF00069	0.427
MOD_Plk_1	69	75	PF00069	0.514
MOD_Plk_4	119	125	PF00069	0.280
MOD_Plk_4	194	200	PF00069	0.436
MOD_SUMO_rev_2	36	43	PF00179	0.525
TRG_DiLeu_BaEn_1	18	23	PF01217	0.641
TRG_DiLeu_BaEn_1	92	97	PF01217	0.439
TRG_ENDOCYTIC_2	151	154	PF00928	0.448
TRG_ENDOCYTIC_2	34	37	PF00928	0.652
TRG_ER_diArg_1	144	147	PF00400	0.492
TRG_NES_CRM1_1	148	162	PF08389	0.438

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBR7	Leptomonas seymouri	90%	100%
A0A0S4JQ09	Bodo saltans	45%	99%
A0A1X0NM53	Trypanosomatidae	72%	98%
A0A3S7WRW2	Leishmania donovani	97%	100%
A0A422N6G0	Trypanosoma rangeli	70%	98%
A4H6S4	Leishmania braziliensis	94%	100%
A4HV52	Leishmania infantum	97%	73%
C9ZQD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	100%
Q4QGT5	Leishmania major	97%	100%