Ribonuclease mar1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Ribonuclease mar1

Gene product:

ribonuclease mar1

Species:

Leishmania mexicana

UniProt:

E9ANT2_LEIMU

TriTrypDb:

LmxM.12.0060

Length:

192

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 10

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ANT2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANT2

PDB structure(s): 1x9g_A , 1xn4_A

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	125	127	PF00082	0.285
CLV_PCSK_KEX2_1	26	28	PF00082	0.356
CLV_PCSK_PC1ET2_1	125	127	PF00082	0.292
CLV_PCSK_PC1ET2_1	26	28	PF00082	0.356
CLV_PCSK_SKI1_1	12	16	PF00082	0.298
CLV_PCSK_SKI1_1	125	129	PF00082	0.335
CLV_PCSK_SKI1_1	182	186	PF00082	0.703
CLV_PCSK_SKI1_1	26	30	PF00082	0.148
DOC_MAPK_gen_1	10	18	PF00069	0.412
DOC_MAPK_gen_1	182	192	PF00069	0.703
DOC_MAPK_gen_1	82	90	PF00069	0.429
DOC_MAPK_MEF2A_6	12	20	PF00069	0.424
DOC_MAPK_MEF2A_6	66	73	PF00069	0.500
DOC_MAPK_MEF2A_6	84	92	PF00069	0.338
DOC_USP7_UBL2_3	139	143	PF12436	0.543
DOC_USP7_UBL2_3	178	182	PF12436	0.679
LIG_14-3-3_CanoR_1	84	92	PF00244	0.522
LIG_Actin_WH2_2	81	99	PF00022	0.495
LIG_BIR_II_1	1	5	PF00653	0.557
LIG_FHA_1	11	17	PF00498	0.424
LIG_FHA_1	50	56	PF00498	0.537
LIG_FHA_1	74	80	PF00498	0.505
LIG_FHA_2	114	120	PF00498	0.492
LIG_LIR_Gen_1	13	23	PF02991	0.527
LIG_LIR_Gen_1	83	92	PF02991	0.512
LIG_LIR_Nem_3	13	18	PF02991	0.527
LIG_LIR_Nem_3	174	180	PF02991	0.568
LIG_LIR_Nem_3	83	88	PF02991	0.512
LIG_MAD2	66	74	PF02301	0.500
LIG_PTB_Apo_2	30	37	PF02174	0.537
LIG_SH2_STAT5	54	57	PF00017	0.459
LIG_SH3_3	124	130	PF00018	0.537
LIG_UBA3_1	120	125	PF00899	0.442
LIG_UBA3_1	164	170	PF00899	0.612
MOD_CK2_1	156	162	PF00069	0.541
MOD_GSK3_1	133	140	PF00069	0.537
MOD_GSK3_1	156	163	PF00069	0.547
MOD_GSK3_1	6	13	PF00069	0.526
MOD_GSK3_1	69	76	PF00069	0.489
MOD_NEK2_1	148	153	PF00069	0.634
MOD_NEK2_1	184	189	PF00069	0.679
MOD_PIKK_1	133	139	PF00454	0.462
MOD_PKA_2	83	89	PF00069	0.522
MOD_Plk_1	69	75	PF00069	0.517
MOD_Plk_1	80	86	PF00069	0.549
MOD_Plk_4	160	166	PF00069	0.534
MOD_SUMO_rev_2	136	145	PF00179	0.537
MOD_SUMO_rev_2	171	177	PF00179	0.405
TRG_NES_CRM1_1	119	132	PF08389	0.497
TRG_NES_CRM1_1	93	108	PF08389	0.478
TRG_Pf-PMV_PEXEL_1	182	186	PF00026	0.704

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P932	Leptomonas seymouri	33%	80%
A0A0N1HWD2	Leptomonas seymouri	77%	100%
A0A0N1I400	Leptomonas seymouri	31%	80%
A0A0N1IAK4	Leptomonas seymouri	36%	92%
A0A0S4IL71	Bodo saltans	47%	98%
A0A0S4IVV9	Bodo saltans	54%	99%
A0A1X0NQH8	Trypanosomatidae	46%	98%
A0A3S5H641	Leishmania donovani	29%	76%
A0A3S5H642	Leishmania donovani	37%	85%
A0A3S5IQS6	Trypanosoma rangeli	43%	98%
A0JME6	Danio rerio	38%	97%
A4H5A0	Leishmania braziliensis	32%	76%
A4H5A2	Leishmania braziliensis	36%	100%
A4H6S1	Leishmania braziliensis	83%	100%
A4HTI1	Leishmania infantum	29%	76%
A4HTI3	Leishmania infantum	37%	85%
A4HV50	Leishmania infantum	92%	100%
B5X0W9	Salmo salar	38%	68%
D0VWV0	Leishmania donovani	92%	100%
E9AMA9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	76%
E9AMB0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9AMB1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
G4YEI5	Phytophthora sojae (strain P6497)	32%	91%
P85094	Mus musculus	36%	93%
Q08C33	Danio rerio	35%	68%
Q32KX0	Bos taurus	35%	94%
Q4QGT7	Leishmania major	90%	100%
Q4QID7	Leishmania major	37%	100%
Q4QID9	Leishmania major	31%	76%
Q4R826	Macaca fascicularis	37%	94%
Q54NZ6	Dictyostelium discoideum	32%	93%
Q54NZ8	Dictyostelium discoideum	31%	93%
Q54RC7	Dictyostelium discoideum	26%	90%
Q54RF0	Dictyostelium discoideum	25%	96%
Q5PQ71	Xenopus laevis	39%	94%
Q5RC03	Pongo abelii	37%	94%
Q5U3Z3	Rattus norvegicus	36%	91%
Q6DF67	Xenopus tropicalis	39%	94%
Q96AB3	Homo sapiens	38%	94%
Q9DCC7	Mus musculus	37%	91%
V5AQ92	Trypanosoma cruzi	52%	100%