Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ANR7_LEIMU

TriTrypDb:

LmxM.11.1300

Length:

186

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ANR7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANR7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	125	127	PF00675	0.453
CLV_NRD_NRD_1	166	168	PF00675	0.457
CLV_NRD_NRD_1	51	53	PF00675	0.410
CLV_NRD_NRD_1	63	65	PF00675	0.434
CLV_PCSK_KEX2_1	125	127	PF00082	0.453
CLV_PCSK_KEX2_1	50	52	PF00082	0.428
CLV_PCSK_KEX2_1	62	64	PF00082	0.417
CLV_PCSK_KEX2_1	87	89	PF00082	0.552
CLV_PCSK_PC1ET2_1	87	89	PF00082	0.552
CLV_PCSK_SKI1_1	147	151	PF00082	0.504
DEG_Nend_UBRbox_1	1	4	PF02207	0.485
DOC_ANK_TNKS_1	42	49	PF00023	0.486
DOC_MAPK_gen_1	112	120	PF00069	0.421
DOC_WW_Pin1_4	181	186	PF00397	0.571
LIG_14-3-3_CanoR_1	139	145	PF00244	0.495
LIG_14-3-3_CanoR_1	147	153	PF00244	0.506
LIG_14-3-3_CanoR_1	2	8	PF00244	0.450
LIG_14-3-3_CanoR_1	31	39	PF00244	0.448
LIG_14-3-3_CanoR_1	62	67	PF00244	0.445
LIG_BRCT_BRCA1_1	52	56	PF00533	0.468
LIG_BRCT_BRCA1_2	52	58	PF00533	0.477
LIG_EVH1_2	145	149	PF00568	0.407
LIG_FHA_1	17	23	PF00498	0.491
LIG_FHA_1	55	61	PF00498	0.367
LIG_FHA_1	81	87	PF00498	0.594
LIG_FHA_2	149	155	PF00498	0.405
LIG_FHA_2	79	85	PF00498	0.623
LIG_FHA_2	8	14	PF00498	0.559
LIG_SH2_STAT3	113	116	PF00017	0.429
LIG_WW_3	144	148	PF00397	0.453
MOD_CK1_1	3	9	PF00069	0.614
MOD_CK1_1	34	40	PF00069	0.519
MOD_CK1_1	80	86	PF00069	0.586
MOD_CK1_1	96	102	PF00069	0.531
MOD_CK2_1	130	136	PF00069	0.517
MOD_CK2_1	148	154	PF00069	0.316
MOD_CK2_1	15	21	PF00069	0.538
MOD_CK2_1	7	13	PF00069	0.578
MOD_CK2_1	78	84	PF00069	0.657
MOD_GlcNHglycan	181	184	PF01048	0.538
MOD_GlcNHglycan	5	8	PF01048	0.428
MOD_GlcNHglycan	69	72	PF01048	0.424
MOD_GlcNHglycan	73	76	PF01048	0.445
MOD_GSK3_1	148	155	PF00069	0.409
MOD_GSK3_1	3	10	PF00069	0.561
MOD_GSK3_1	50	57	PF00069	0.432
MOD_GSK3_1	67	74	PF00069	0.617
MOD_GSK3_1	95	102	PF00069	0.641
MOD_N-GLC_1	100	105	PF02516	0.508
MOD_NEK2_1	148	153	PF00069	0.487
MOD_NEK2_1	95	100	PF00069	0.585
MOD_PIKK_1	31	37	PF00454	0.471
MOD_PKA_1	50	56	PF00069	0.414
MOD_PKA_1	62	68	PF00069	0.529
MOD_PKA_2	179	185	PF00069	0.562
MOD_PKA_2	50	56	PF00069	0.431
MOD_PKA_2	62	68	PF00069	0.529
MOD_Plk_1	120	126	PF00069	0.509
MOD_Plk_4	34	40	PF00069	0.460
TRG_DiLeu_BaLyEn_6	28	33	PF01217	0.399
TRG_ENDOCYTIC_2	128	131	PF00928	0.524
TRG_ER_diArg_1	124	126	PF00400	0.433
TRG_ER_diArg_1	49	52	PF00400	0.394
TRG_ER_diArg_1	62	64	PF00400	0.455
TRG_Pf-PMV_PEXEL_1	107	111	PF00026	0.477
TRG_Pf-PMV_PEXEL_1	31	35	PF00026	0.466

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2F7	Leptomonas seymouri	60%	98%
A0A1X0NWA0	Trypanosomatidae	35%	95%
A0A3S7WRU4	Leishmania donovani	87%	100%
A0A422N1X3	Trypanosoma rangeli	33%	91%
A4H6Q1	Leishmania braziliensis	74%	100%
A4HV36	Leishmania infantum	88%	100%
D0A7B5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	98%
Q4QGV2	Leishmania major	87%	100%