Putative ATP-binding cassette protein subfamily A, member 2

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-binding cassette protein subfamily A, member 2, putative

Species:

Leishmania mexicana

UniProt:

E9ANR1_LEIMU

TriTrypDb:

LmxM.11.1220

Length:

1686

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 6

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 47
NetGPI	no	yes: 0, no: 47

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	48
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0043229	intracellular organelle	3	7
GO:0043231	intracellular membrane-bounded organelle	4	7
GO:0110165	cellular anatomical entity	1	48

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Expansion

Sequence features

E9ANR1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	7
GO:0006869	lipid transport	5	7
GO:0051179	localization	1	7
GO:0051234	establishment of localization	2	7
GO:0071702	organic substance transport	4	7

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	48
GO:0003824	catalytic activity	1	1
GO:0005215	transporter activity	1	48
GO:0005319	lipid transporter activity	2	7
GO:0005488	binding	1	48
GO:0005524	ATP binding	5	48
GO:0015399	primary active transmembrane transporter activity	4	48
GO:0016787	hydrolase activity	2	1
GO:0017076	purine nucleotide binding	4	48
GO:0022804	active transmembrane transporter activity	3	48

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1297	1301	PF00656	0.277
CLV_C14_Caspase3-7	33	37	PF00656	0.519
CLV_C14_Caspase3-7	332	336	PF00656	0.197
CLV_C14_Caspase3-7	8	12	PF00656	0.564
CLV_NRD_NRD_1	1048	1050	PF00675	0.489
CLV_NRD_NRD_1	1131	1133	PF00675	0.253
CLV_NRD_NRD_1	128	130	PF00675	0.452
CLV_NRD_NRD_1	1517	1519	PF00675	0.301
CLV_NRD_NRD_1	1546	1548	PF00675	0.394
CLV_NRD_NRD_1	1667	1669	PF00675	0.280

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0G2K1Q8	Rattus norvegicus	31%	99%
A0A0N0P411	Leptomonas seymouri	46%	84%
A0A0N1I1A6	Leptomonas seymouri	29%	90%
A0A0N1IH55	Leptomonas seymouri	62%	90%
A0A0S4IQH9	Bodo saltans	32%	89%
A0A0S4IUV3	Bodo saltans	47%	91%
A0A0S4IZR8	Bodo saltans	39%	100%
A0A0S4J5Z1	Bodo saltans	47%	92%
A0A0S4J9S9	Bodo saltans	39%	92%
A0A0S4JDK3	Bodo saltans	38%	89%

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