Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9ANQ0_LEIMU

TriTrypDb:

LmxM.11.1070

Length:

169

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ANQ0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANQ0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	21	23	PF00675	0.560
CLV_PCSK_KEX2_1	21	23	PF00082	0.554
CLV_PCSK_SKI1_1	26	30	PF00082	0.748
CLV_PCSK_SKI1_1	58	62	PF00082	0.479
CLV_PCSK_SKI1_1	91	95	PF00082	0.477
DEG_APCC_DBOX_1	32	40	PF00400	0.508
DEG_SCF_FBW7_2	162	169	PF00400	0.515
DOC_MAPK_gen_1	21	29	PF00069	0.569
DOC_MAPK_MEF2A_6	152	160	PF00069	0.537
DOC_PP2B_LxvP_1	41	44	PF13499	0.467
DOC_USP7_MATH_1	111	115	PF00917	0.623
DOC_USP7_MATH_1	89	93	PF00917	0.580
DOC_USP7_UBL2_3	87	91	PF12436	0.586
DOC_WW_Pin1_4	146	151	PF00397	0.599
DOC_WW_Pin1_4	162	167	PF00397	0.542
DOC_WW_Pin1_4	98	103	PF00397	0.586
LIG_14-3-3_CanoR_1	104	108	PF00244	0.582
LIG_14-3-3_CanoR_1	42	48	PF00244	0.572
LIG_14-3-3_CanoR_1	66	75	PF00244	0.482
LIG_BIR_II_1	1	5	PF00653	0.647
LIG_FHA_1	104	110	PF00498	0.657
LIG_FHA_1	23	29	PF00498	0.579
LIG_FHA_1	36	42	PF00498	0.470
LIG_FHA_1	44	50	PF00498	0.576
LIG_FHA_1	68	74	PF00498	0.484
LIG_FHA_2	163	169	PF00498	0.516
LIG_Integrin_RGD_1	33	35	PF01839	0.485
LIG_Integrin_RGD_TGFB_3	33	39	PF01839	0.465
LIG_SH2_CRK	100	104	PF00017	0.588
LIG_SH2_STAT5	100	103	PF00017	0.704
LIG_SH3_3	144	150	PF00018	0.628
LIG_TRAF2_1	114	117	PF00917	0.614
LIG_TRAF2_1	118	121	PF00917	0.596
LIG_TRAF2_1	128	131	PF00917	0.519
LIG_TRAF2_1	166	169	PF00917	0.620
LIG_TYR_ITIM	98	103	PF00017	0.586
MOD_CDC14_SPxK_1	149	152	PF00782	0.518
MOD_CDK_SPxK_1	146	152	PF00069	0.525
MOD_CDK_SPxK_1	98	104	PF00069	0.587
MOD_CK1_1	142	148	PF00069	0.631
MOD_CK1_1	4	10	PF00069	0.495
MOD_CK1_1	92	98	PF00069	0.582
MOD_CK2_1	111	117	PF00069	0.621
MOD_CK2_1	142	148	PF00069	0.631
MOD_CK2_1	162	168	PF00069	0.484
MOD_GlcNHglycan	1	4	PF01048	0.522
MOD_GlcNHglycan	141	144	PF01048	0.788
MOD_GlcNHglycan	70	73	PF01048	0.598
MOD_GlcNHglycan	90	94	PF01048	0.626
MOD_GSK3_1	139	146	PF00069	0.583
MOD_N-GLC_1	67	72	PF02516	0.538
MOD_NEK2_1	1	6	PF00069	0.615
MOD_NEK2_1	139	144	PF00069	0.649
MOD_PIKK_1	16	22	PF00454	0.472
MOD_PKA_2	103	109	PF00069	0.614
MOD_PKA_2	139	145	PF00069	0.527
MOD_Plk_4	35	41	PF00069	0.638
MOD_Plk_4	92	98	PF00069	0.553
MOD_ProDKin_1	146	152	PF00069	0.596
MOD_ProDKin_1	162	168	PF00069	0.541
MOD_ProDKin_1	98	104	PF00069	0.587
MOD_SUMO_rev_2	125	134	PF00179	0.621
TRG_ENDOCYTIC_2	100	103	PF00928	0.777

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IHI7	Leishmania donovani	76%	71%
Q4QGX3	Leishmania major	74%	100%