MIT domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ANM0_LEIMU

TriTrypDb:

LmxM.11.0750

Length:

205

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 4
Forrest at al. (procyclic)	no	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ANM0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANM0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	118	122	PF00656	0.515
CLV_C14_Caspase3-7	95	99	PF00656	0.565
CLV_NRD_NRD_1	58	60	PF00675	0.438
CLV_PCSK_KEX2_1	47	49	PF00082	0.499
CLV_PCSK_KEX2_1	58	60	PF00082	0.398
CLV_PCSK_PC1ET2_1	47	49	PF00082	0.470
CLV_PCSK_SKI1_1	58	62	PF00082	0.430
DEG_APCC_DBOX_1	58	66	PF00400	0.432
DOC_CKS1_1	185	190	PF01111	0.658
DOC_CYCLIN_yCln2_LP_2	139	145	PF00134	0.673
DOC_CYCLIN_yCln2_LP_2	148	154	PF00134	0.622
DOC_MAPK_MEF2A_6	75	82	PF00069	0.443
DOC_MAPK_NFAT4_5	75	83	PF00069	0.439
DOC_PP2B_LxvP_1	139	142	PF13499	0.684
DOC_PP2B_LxvP_1	148	151	PF13499	0.728
DOC_PP2B_LxvP_1	199	202	PF13499	0.682
DOC_USP7_MATH_1	128	132	PF00917	0.581
DOC_USP7_MATH_1	51	55	PF00917	0.392
DOC_USP7_MATH_1	83	87	PF00917	0.485
DOC_WW_Pin1_4	154	159	PF00397	0.748
DOC_WW_Pin1_4	184	189	PF00397	0.722
LIG_14-3-3_CanoR_1	32	41	PF00244	0.426
LIG_APCC_ABBA_1	69	74	PF00400	0.400
LIG_APCC_ABBAyCdc20_2	68	74	PF00400	0.402
LIG_BIR_II_1	1	5	PF00653	0.581
LIG_EVH1_2	107	111	PF00568	0.599
LIG_EVH1_2	167	171	PF00568	0.504
LIG_FAT_LD_1	192	200	PF03623	0.674
LIG_FHA_1	185	191	PF00498	0.661
LIG_FHA_1	2	8	PF00498	0.344
LIG_FHA_2	34	40	PF00498	0.409
LIG_LIR_Apic_2	159	164	PF02991	0.606
LIG_LIR_Apic_2	170	175	PF02991	0.642
LIG_SH2_CRK	161	165	PF00017	0.536
LIG_SH2_GRB2like	161	164	PF00017	0.538
LIG_SH2_SRC	161	164	PF00017	0.610
LIG_SH2_STAP1	9	13	PF00017	0.614
LIG_SH2_STAT3	9	12	PF00017	0.514
LIG_SH2_STAT5	172	175	PF00017	0.660
LIG_SH2_STAT5	34	37	PF00017	0.394
LIG_SH3_1	161	167	PF00018	0.526
LIG_SH3_3	139	145	PF00018	0.663
LIG_SH3_3	148	154	PF00018	0.740
LIG_SH3_3	161	167	PF00018	0.549
LIG_SH3_3	182	188	PF00018	0.692
LIG_Sin3_3	76	83	PF02671	0.438
LIG_TRFH_1	171	175	PF08558	0.524
MOD_CK1_1	113	119	PF00069	0.710
MOD_CK1_1	120	126	PF00069	0.541
MOD_CK1_1	43	49	PF00069	0.596
MOD_CK1_1	93	99	PF00069	0.503
MOD_CK2_1	33	39	PF00069	0.398
MOD_CK2_1	64	70	PF00069	0.584
MOD_GlcNHglycan	112	115	PF01048	0.796
MOD_GlcNHglycan	85	88	PF01048	0.509
MOD_GlcNHglycan	95	98	PF01048	0.618
MOD_GSK3_1	113	120	PF00069	0.619
MOD_GSK3_1	152	159	PF00069	0.768
MOD_GSK3_1	98	105	PF00069	0.772
MOD_N-GLC_1	83	88	PF02516	0.515
MOD_NEK2_1	102	107	PF00069	0.665
MOD_NEK2_1	110	115	PF00069	0.693
MOD_NEK2_1	129	134	PF00069	0.651
MOD_PIKK_1	152	158	PF00454	0.748
MOD_Plk_4	134	140	PF00069	0.645
MOD_Plk_4	167	173	PF00069	0.743
MOD_ProDKin_1	154	160	PF00069	0.744
MOD_ProDKin_1	184	190	PF00069	0.720
TRG_DiLeu_BaEn_1	74	79	PF01217	0.411
TRG_ER_diArg_1	58	60	PF00400	0.438

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I225	Leptomonas seymouri	59%	100%
A0A1X0NDQ9	Trypanosomatidae	39%	100%
A0A3Q8I937	Leishmania donovani	85%	100%
A0A3R7KJF9	Trypanosoma rangeli	40%	100%
A4H6K0	Leishmania braziliensis	70%	97%
A4HUY5	Leishmania infantum	85%	100%
Q4QH03	Leishmania major	86%	100%