LeishMANIAdb
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MFS transporter

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
MFS transporter
Gene product:
hypothetical protein, conserved in leishmania
Species:
Leishmania mexicana
UniProt:
E9ANL3_LEIMU
TriTrypDb:
LmxM.11.0675
Length:
111

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Cellular components
Term Name Level Count
GO:0016020 membrane 2 4
GO:0110165 cellular anatomical entity 1 4

Expansion

Sequence features

E9ANL3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANL3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 86 88 PF00675 0.522
CLV_NRD_NRD_1 95 97 PF00675 0.415
CLV_PCSK_KEX2_1 86 88 PF00082 0.522
CLV_PCSK_KEX2_1 97 99 PF00082 0.392
CLV_PCSK_PC1ET2_1 97 99 PF00082 0.530
DEG_Nend_Nbox_1 1 3 PF02207 0.708
DOC_MAPK_gen_1 86 93 PF00069 0.711
DOC_MAPK_MEF2A_6 98 107 PF00069 0.730
DOC_PP4_FxxP_1 41 44 PF00568 0.395
DOC_USP7_MATH_1 4 8 PF00917 0.681
DOC_WW_Pin1_4 96 101 PF00397 0.730
LIG_14-3-3_CanoR_1 26 34 PF00244 0.583
LIG_BRCT_BRCA1_1 6 10 PF00533 0.609
LIG_FHA_2 45 51 PF00498 0.614
LIG_FHA_2 73 79 PF00498 0.483
LIG_LIR_Apic_2 50 54 PF02991 0.424
LIG_LIR_Gen_1 47 57 PF02991 0.527
LIG_LIR_Gen_1 7 17 PF02991 0.573
LIG_LIR_Gen_1 75 84 PF02991 0.578
LIG_LIR_Nem_3 47 52 PF02991 0.491
LIG_LIR_Nem_3 7 13 PF02991 0.574
LIG_LIR_Nem_3 75 79 PF02991 0.530
LIG_NRBOX 66 72 PF00104 0.395
LIG_SH2_CRK 45 49 PF00017 0.317
LIG_SH2_STAP1 8 12 PF00017 0.612
LIG_SH2_STAT5 40 43 PF00017 0.343
LIG_SH2_STAT5 51 54 PF00017 0.384
LIG_SH2_STAT5 58 61 PF00017 0.343
LIG_SH3_1 97 103 PF00018 0.729
LIG_SH3_3 97 103 PF00018 0.729
LIG_TRFH_1 40 44 PF08558 0.395
LIG_TYR_ITIM 43 48 PF00017 0.395
LIG_WW_2 103 106 PF00397 0.744
MOD_CK1_1 99 105 PF00069 0.733
MOD_GlcNHglycan 13 16 PF01048 0.393
MOD_GSK3_1 22 29 PF00069 0.607
MOD_GSK3_1 92 99 PF00069 0.682
MOD_NEK2_1 13 18 PF00069 0.590
MOD_NEK2_1 72 77 PF00069 0.308
MOD_NEK2_1 92 97 PF00069 0.473
MOD_NEK2_2 44 49 PF00069 0.483
MOD_Plk_4 44 50 PF00069 0.398
MOD_Plk_4 80 86 PF00069 0.604
MOD_ProDKin_1 96 102 PF00069 0.730
TRG_ENDOCYTIC_2 40 43 PF00928 0.343
TRG_ENDOCYTIC_2 45 48 PF00928 0.343
TRG_ENDOCYTIC_2 49 52 PF00928 0.384
TRG_ER_diArg_1 85 87 PF00400 0.719
TRG_NLS_Bipartite_1 86 100 PF00514 0.718
TRG_NLS_MonoExtC_3 95 100 PF00514 0.727

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HYC6 Leptomonas seymouri 34% 77%
A0A3R7K9F3 Trypanosoma rangeli 45% 71%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS