Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9ANJ2_LEIMU

TriTrypDb:

LmxM.11.0460

Length:

644

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ANJ2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANJ2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	193	197	PF00656	0.592
CLV_C14_Caspase3-7	403	407	PF00656	0.594
CLV_C14_Caspase3-7	580	584	PF00656	0.537
CLV_MEL_PAP_1	70	76	PF00089	0.608
CLV_NRD_NRD_1	152	154	PF00675	0.527
CLV_NRD_NRD_1	2	4	PF00675	0.632
CLV_NRD_NRD_1	278	280	PF00675	0.556
CLV_NRD_NRD_1	297	299	PF00675	0.548
CLV_NRD_NRD_1	591	593	PF00675	0.552
CLV_NRD_NRD_1	93	95	PF00675	0.587
CLV_PCSK_KEX2_1	151	153	PF00082	0.532
CLV_PCSK_KEX2_1	2	4	PF00082	0.632
CLV_PCSK_KEX2_1	278	280	PF00082	0.556
CLV_PCSK_KEX2_1	297	299	PF00082	0.548
CLV_PCSK_KEX2_1	591	593	PF00082	0.616
CLV_PCSK_SKI1_1	3	7	PF00082	0.598
CLV_PCSK_SKI1_1	561	565	PF00082	0.608
CLV_PCSK_SKI1_1	591	595	PF00082	0.616
CLV_PCSK_SKI1_1	603	607	PF00082	0.455
CLV_PCSK_SKI1_1	609	613	PF00082	0.601
DEG_APCC_DBOX_1	560	568	PF00400	0.563
DEG_Nend_UBRbox_1	1	4	PF02207	0.631
DEG_SCF_FBW7_1	397	403	PF00400	0.497
DEG_SPOP_SBC_1	183	187	PF00917	0.643
DEG_SPOP_SBC_1	19	23	PF00917	0.627
DEG_SPOP_SBC_1	241	245	PF00917	0.529
DOC_CKS1_1	397	402	PF01111	0.492
DOC_CYCLIN_RxL_1	588	598	PF00134	0.602
DOC_CYCLIN_yCln2_LP_2	442	448	PF00134	0.455
DOC_MAPK_gen_1	223	232	PF00069	0.615
DOC_MAPK_gen_1	294	303	PF00069	0.648
DOC_MAPK_MEF2A_6	297	305	PF00069	0.493
DOC_PP1_RVXF_1	590	597	PF00149	0.557
DOC_PP2B_LxvP_1	172	175	PF13499	0.677
DOC_PP2B_LxvP_1	555	558	PF13499	0.513
DOC_SPAK_OSR1_1	73	77	PF12202	0.429
DOC_USP7_MATH_1	107	111	PF00917	0.639
DOC_USP7_MATH_1	112	116	PF00917	0.678
DOC_USP7_MATH_1	177	181	PF00917	0.622
DOC_USP7_MATH_1	188	192	PF00917	0.612
DOC_USP7_MATH_1	19	23	PF00917	0.600
DOC_USP7_MATH_1	241	245	PF00917	0.547
DOC_USP7_MATH_1	39	43	PF00917	0.572
DOC_USP7_MATH_1	429	433	PF00917	0.590
DOC_USP7_MATH_1	497	501	PF00917	0.754
DOC_USP7_MATH_1	534	538	PF00917	0.651
DOC_USP7_MATH_1	607	611	PF00917	0.590
DOC_USP7_MATH_1	628	632	PF00917	0.511
DOC_USP7_MATH_1	85	89	PF00917	0.626
DOC_WW_Pin1_4	184	189	PF00397	0.774
DOC_WW_Pin1_4	205	210	PF00397	0.667
DOC_WW_Pin1_4	390	395	PF00397	0.703
DOC_WW_Pin1_4	396	401	PF00397	0.641
DOC_WW_Pin1_4	422	427	PF00397	0.660
DOC_WW_Pin1_4	441	446	PF00397	0.508
DOC_WW_Pin1_4	614	619	PF00397	0.615
LIG_14-3-3_CanoR_1	134	139	PF00244	0.638
LIG_14-3-3_CanoR_1	164	172	PF00244	0.555
LIG_14-3-3_CanoR_1	226	230	PF00244	0.646
LIG_14-3-3_CanoR_1	298	304	PF00244	0.529
LIG_14-3-3_CanoR_1	352	361	PF00244	0.640
LIG_14-3-3_CanoR_1	433	441	PF00244	0.549
LIG_14-3-3_CanoR_1	591	597	PF00244	0.608
LIG_14-3-3_CanoR_1	603	611	PF00244	0.465
LIG_14-3-3_CanoR_1	68	73	PF00244	0.534
LIG_Actin_WH2_2	262	280	PF00022	0.584
LIG_AP2alpha_1	460	464	PF02296	0.419
LIG_BIR_III_4	409	413	PF00653	0.529
LIG_BRCT_BRCA1_1	114	118	PF00533	0.600
LIG_BRCT_BRCA1_1	630	634	PF00533	0.598
LIG_BRCT_BRCA1_1	70	74	PF00533	0.536
LIG_CaM_IQ_9	296	311	PF13499	0.567
LIG_FHA_1	184	190	PF00498	0.682
LIG_FHA_1	363	369	PF00498	0.613
LIG_FHA_1	400	406	PF00498	0.680
LIG_FHA_1	433	439	PF00498	0.625
LIG_FHA_1	53	59	PF00498	0.556
LIG_FHA_1	538	544	PF00498	0.715
LIG_FHA_1	636	642	PF00498	0.646
LIG_FHA_2	352	358	PF00498	0.585
LIG_FHA_2	401	407	PF00498	0.634
LIG_FHA_2	578	584	PF00498	0.631
LIG_FHA_2	596	602	PF00498	0.509
LIG_FHA_2	610	616	PF00498	0.593
LIG_Integrin_isoDGR_2	132	134	PF01839	0.580
LIG_LIR_Gen_1	228	236	PF02991	0.595
LIG_LIR_Gen_1	462	472	PF02991	0.582
LIG_LIR_Nem_3	216	221	PF02991	0.564
LIG_LIR_Nem_3	228	232	PF02991	0.568
LIG_LIR_Nem_3	462	467	PF02991	0.582
LIG_LIR_Nem_3	631	637	PF02991	0.601
LIG_MAD2	440	448	PF02301	0.451
LIG_MYND_1	170	174	PF01753	0.598
LIG_NBox_RRM_1	616	626	PF00076	0.563
LIG_PCNA_PIPBox_1	270	279	PF02747	0.587
LIG_Pex14_1	214	218	PF04695	0.541
LIG_Pex14_2	460	464	PF04695	0.419
LIG_SH2_GRB2like	548	551	PF00017	0.572
LIG_SH2_NCK_1	254	258	PF00017	0.622
LIG_SH2_PTP2	229	232	PF00017	0.586
LIG_SH2_STAP1	637	641	PF00017	0.612
LIG_SH2_STAT3	548	551	PF00017	0.463
LIG_SH2_STAT5	165	168	PF00017	0.504
LIG_SH2_STAT5	229	232	PF00017	0.586
LIG_SH2_STAT5	369	372	PF00017	0.641
LIG_SH2_STAT5	437	440	PF00017	0.604
LIG_SH2_STAT5	548	551	PF00017	0.475
LIG_SH2_STAT5	637	640	PF00017	0.563
LIG_SH3_1	173	179	PF00018	0.634
LIG_SH3_1	32	38	PF00018	0.536
LIG_SH3_2	63	68	PF14604	0.558
LIG_SH3_3	168	174	PF00018	0.644
LIG_SH3_3	206	212	PF00018	0.605
LIG_SH3_3	245	251	PF00018	0.617
LIG_SH3_3	32	38	PF00018	0.536
LIG_SH3_3	391	397	PF00018	0.605
LIG_SH3_3	442	448	PF00018	0.455
LIG_SH3_3	60	66	PF00018	0.574
LIG_SH3_5	250	254	PF00018	0.599
LIG_SUMO_SIM_anti_2	126	131	PF11976	0.517
LIG_TRAF2_1	256	259	PF00917	0.586
LIG_TRAF2_1	338	341	PF00917	0.710
LIG_WRC_WIRS_1	461	466	PF05994	0.585
MOD_CK1_1	119	125	PF00069	0.711
MOD_CK1_1	128	134	PF00069	0.700
MOD_CK1_1	137	143	PF00069	0.567
MOD_CK1_1	18	24	PF00069	0.624
MOD_CK1_1	225	231	PF00069	0.550
MOD_CK1_1	327	333	PF00069	0.620
MOD_CK1_1	393	399	PF00069	0.682
MOD_CK1_1	4	10	PF00069	0.699
MOD_CK1_1	432	438	PF00069	0.593
MOD_CK1_1	537	543	PF00069	0.439
MOD_CK1_1	595	601	PF00069	0.598
MOD_CK1_1	88	94	PF00069	0.672
MOD_CK2_1	225	231	PF00069	0.546
MOD_CK2_1	284	290	PF00069	0.630
MOD_CK2_1	351	357	PF00069	0.524
MOD_CK2_1	422	428	PF00069	0.655
MOD_CK2_1	497	503	PF00069	0.578
MOD_CK2_1	595	601	PF00069	0.511
MOD_GlcNHglycan	107	110	PF01048	0.642
MOD_GlcNHglycan	17	20	PF01048	0.608
MOD_GlcNHglycan	190	193	PF01048	0.636
MOD_GlcNHglycan	244	247	PF01048	0.679
MOD_GlcNHglycan	262	265	PF01048	0.388
MOD_GlcNHglycan	286	289	PF01048	0.754
MOD_GlcNHglycan	3	6	PF01048	0.717
MOD_GlcNHglycan	331	334	PF01048	0.656
MOD_GlcNHglycan	414	417	PF01048	0.797
MOD_GlcNHglycan	489	492	PF01048	0.629
MOD_GlcNHglycan	499	502	PF01048	0.568
MOD_GlcNHglycan	535	539	PF01048	0.457
MOD_GlcNHglycan	87	90	PF01048	0.771
MOD_GSK3_1	112	119	PF00069	0.601
MOD_GSK3_1	133	140	PF00069	0.503
MOD_GSK3_1	15	22	PF00069	0.653
MOD_GSK3_1	184	191	PF00069	0.623
MOD_GSK3_1	320	327	PF00069	0.577
MOD_GSK3_1	352	359	PF00069	0.616
MOD_GSK3_1	396	403	PF00069	0.673
MOD_GSK3_1	432	439	PF00069	0.535
MOD_GSK3_1	493	500	PF00069	0.707
MOD_GSK3_1	603	610	PF00069	0.654
MOD_GSK3_1	68	75	PF00069	0.653
MOD_GSK3_1	80	87	PF00069	0.591
MOD_N-GLC_1	119	124	PF02516	0.646
MOD_N-GLC_1	134	139	PF02516	0.520
MOD_N-GLC_1	328	333	PF02516	0.704
MOD_N-GLC_1	352	357	PF02516	0.720
MOD_NEK2_1	1	6	PF00069	0.661
MOD_NEK2_1	182	187	PF00069	0.717
MOD_NEK2_1	299	304	PF00069	0.569
MOD_NEK2_1	460	465	PF00069	0.414
MOD_NEK2_1	51	56	PF00069	0.658
MOD_NEK2_1	80	85	PF00069	0.601
MOD_NEK2_2	637	642	PF00069	0.622
MOD_PIKK_1	321	327	PF00454	0.619
MOD_PK_1	134	140	PF00069	0.635
MOD_PK_1	68	74	PF00069	0.612
MOD_PKA_2	1	7	PF00069	0.788
MOD_PKA_2	133	139	PF00069	0.518
MOD_PKA_2	163	169	PF00069	0.516
MOD_PKA_2	222	228	PF00069	0.562
MOD_PKA_2	284	290	PF00069	0.662
MOD_PKA_2	351	357	PF00069	0.596
MOD_PKA_2	432	438	PF00069	0.587
MOD_PKA_2	577	583	PF00069	0.633
MOD_PKA_2	72	78	PF00069	0.611
MOD_Plk_1	134	140	PF00069	0.612
MOD_Plk_1	145	151	PF00069	0.440
MOD_Plk_1	356	362	PF00069	0.471
MOD_Plk_4	125	131	PF00069	0.647
MOD_Plk_4	145	151	PF00069	0.429
MOD_Plk_4	225	231	PF00069	0.602
MOD_Plk_4	451	457	PF00069	0.606
MOD_Plk_4	460	466	PF00069	0.594
MOD_Plk_4	637	643	PF00069	0.658
MOD_ProDKin_1	184	190	PF00069	0.775
MOD_ProDKin_1	205	211	PF00069	0.660
MOD_ProDKin_1	390	396	PF00069	0.706
MOD_ProDKin_1	422	428	PF00069	0.655
MOD_ProDKin_1	441	447	PF00069	0.509
MOD_ProDKin_1	614	620	PF00069	0.612
MOD_SUMO_rev_2	88	96	PF00179	0.574
TRG_DiLeu_BaLyEn_6	206	211	PF01217	0.587
TRG_DiLeu_BaLyEn_6	47	52	PF01217	0.526
TRG_DiLeu_BaLyEn_6	589	594	PF01217	0.553
TRG_ENDOCYTIC_2	229	232	PF00928	0.586
TRG_ER_diArg_1	1	3	PF00400	0.634
TRG_ER_diArg_1	150	153	PF00400	0.631
TRG_ER_diArg_1	277	279	PF00400	0.534
TRG_ER_diArg_1	297	299	PF00400	0.419
TRG_ER_diArg_1	48	51	PF00400	0.534
TRG_ER_diArg_1	591	593	PF00400	0.559
TRG_NES_CRM1_1	65	77	PF08389	0.431
TRG_Pf-PMV_PEXEL_1	94	99	PF00026	0.610

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P315	Leptomonas seymouri	35%	100%
A0A3Q8I910	Leishmania donovani	90%	100%
A4H6G2	Leishmania braziliensis	73%	100%
A4HUV7	Leishmania infantum	89%	100%
Q4QH34	Leishmania major	87%	100%