ATP-dependent DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PIF1 helicase-like protein, putative

Species:

Leishmania mexicana

UniProt:

E9ANH8_LEIMU

TriTrypDb:

LmxM.11.0320

Length:

1223

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	8
GO:0110165	cellular anatomical entity	1	8
GO:0005657	replication fork	2	1

Expansion

Sequence features

E9ANH8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANH8

Function

Biological processes
Term	Name	Level	Count
GO:0000723	telomere maintenance	5	8
GO:0006139	nucleobase-containing compound metabolic process	3	8
GO:0006259	DNA metabolic process	4	8
GO:0006281	DNA repair	5	8
GO:0006310	DNA recombination	5	8
GO:0006725	cellular aromatic compound metabolic process	3	8
GO:0006807	nitrogen compound metabolic process	2	8
GO:0006950	response to stress	2	8
GO:0006974	DNA damage response	4	8
GO:0006996	organelle organization	4	8
GO:0008152	metabolic process	1	8
GO:0009987	cellular process	1	8
GO:0016043	cellular component organization	3	8
GO:0032200	telomere organization	6	8
GO:0033554	cellular response to stress	3	8
GO:0034641	cellular nitrogen compound metabolic process	3	8
GO:0043170	macromolecule metabolic process	3	8
GO:0044237	cellular metabolic process	2	8
GO:0044238	primary metabolic process	2	8
GO:0044260	obsolete cellular macromolecule metabolic process	3	8
GO:0046483	heterocycle metabolic process	3	8
GO:0050896	response to stimulus	1	8
GO:0051276	chromosome organization	5	8
GO:0051716	cellular response to stimulus	2	8
GO:0071704	organic substance metabolic process	2	8
GO:0071840	cellular component organization or biogenesis	2	8
GO:0090304	nucleic acid metabolic process	4	8
GO:1901360	organic cyclic compound metabolic process	3	8
GO:0006260	DNA replication	5	1
GO:0032392	DNA geometric change	7	1
GO:0032508	DNA duplex unwinding	8	1
GO:0071103	DNA conformation change	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	8
GO:0003678	DNA helicase activity	3	8
GO:0003824	catalytic activity	1	8
GO:0004386	helicase activity	2	8
GO:0005488	binding	1	8
GO:0005524	ATP binding	5	8
GO:0008094	ATP-dependent activity, acting on DNA	2	8
GO:0016462	pyrophosphatase activity	5	8
GO:0016787	hydrolase activity	2	8
GO:0016817	hydrolase activity, acting on acid anhydrides	3	8
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	8
GO:0016887	ATP hydrolysis activity	7	8
GO:0017076	purine nucleotide binding	4	8
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	8
GO:0030554	adenyl nucleotide binding	5	8
GO:0032553	ribonucleotide binding	3	8
GO:0032555	purine ribonucleotide binding	4	8
GO:0032559	adenyl ribonucleotide binding	5	8
GO:0035639	purine ribonucleoside triphosphate binding	4	8
GO:0036094	small molecule binding	2	8
GO:0043167	ion binding	2	8
GO:0043168	anion binding	3	8
GO:0097159	organic cyclic compound binding	2	8
GO:0097367	carbohydrate derivative binding	2	8
GO:0140097	catalytic activity, acting on DNA	3	8
GO:0140640	catalytic activity, acting on a nucleic acid	2	8
GO:0140657	ATP-dependent activity	1	8
GO:1901265	nucleoside phosphate binding	3	8
GO:1901363	heterocyclic compound binding	2	8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	290	294	PF00656	0.826
CLV_C14_Caspase3-7	766	770	PF00656	0.453
CLV_C14_Caspase3-7	80	84	PF00656	0.649
CLV_C14_Caspase3-7	856	860	PF00656	0.424
CLV_C14_Caspase3-7	913	917	PF00656	0.628
CLV_NRD_NRD_1	1147	1149	PF00675	0.546
CLV_NRD_NRD_1	1152	1154	PF00675	0.572
CLV_NRD_NRD_1	1158	1160	PF00675	0.553
CLV_NRD_NRD_1	1168	1170	PF00675	0.521
CLV_NRD_NRD_1	1207	1209	PF00675	0.677
CLV_NRD_NRD_1	217	219	PF00675	0.694
CLV_NRD_NRD_1	227	229	PF00675	0.736
CLV_NRD_NRD_1	337	339	PF00675	0.596
CLV_NRD_NRD_1	552	554	PF00675	0.363
CLV_NRD_NRD_1	583	585	PF00675	0.375
CLV_NRD_NRD_1	621	623	PF00675	0.375
CLV_NRD_NRD_1	649	651	PF00675	0.470
CLV_NRD_NRD_1	736	738	PF00675	0.703
CLV_NRD_NRD_1	812	814	PF00675	0.527
CLV_NRD_NRD_1	839	841	PF00675	0.705
CLV_NRD_NRD_1	90	92	PF00675	0.619
CLV_NRD_NRD_1	982	984	PF00675	0.511
CLV_PCSK_FUR_1	1204	1208	PF00082	0.686
CLV_PCSK_KEX2_1	1147	1149	PF00082	0.535
CLV_PCSK_KEX2_1	1152	1154	PF00082	0.586
CLV_PCSK_KEX2_1	1160	1162	PF00082	0.578
CLV_PCSK_KEX2_1	1168	1170	PF00082	0.521
CLV_PCSK_KEX2_1	1206	1208	PF00082	0.689
CLV_PCSK_KEX2_1	231	233	PF00082	0.787
CLV_PCSK_KEX2_1	316	318	PF00082	0.764
CLV_PCSK_KEX2_1	337	339	PF00082	0.551
CLV_PCSK_KEX2_1	552	554	PF00082	0.375
CLV_PCSK_KEX2_1	583	585	PF00082	0.375
CLV_PCSK_KEX2_1	621	623	PF00082	0.375
CLV_PCSK_KEX2_1	649	651	PF00082	0.470
CLV_PCSK_KEX2_1	735	737	PF00082	0.711
CLV_PCSK_KEX2_1	812	814	PF00082	0.527
CLV_PCSK_KEX2_1	90	92	PF00082	0.751
CLV_PCSK_PC1ET2_1	1160	1162	PF00082	0.681
CLV_PCSK_PC1ET2_1	1206	1208	PF00082	0.689
CLV_PCSK_PC1ET2_1	231	233	PF00082	0.784
CLV_PCSK_PC1ET2_1	316	318	PF00082	0.764
CLV_PCSK_PC7_1	1148	1154	PF00082	0.571
CLV_PCSK_PC7_1	86	92	PF00082	0.727
CLV_PCSK_SKI1_1	1155	1159	PF00082	0.571
CLV_PCSK_SKI1_1	1192	1196	PF00082	0.640
CLV_PCSK_SKI1_1	228	232	PF00082	0.754
CLV_PCSK_SKI1_1	234	238	PF00082	0.719
CLV_PCSK_SKI1_1	338	342	PF00082	0.518
CLV_PCSK_SKI1_1	468	472	PF00082	0.530
CLV_PCSK_SKI1_1	502	506	PF00082	0.375
CLV_PCSK_SKI1_1	507	511	PF00082	0.375
CLV_PCSK_SKI1_1	572	576	PF00082	0.429
CLV_PCSK_SKI1_1	922	926	PF00082	0.588
CLV_PCSK_SKI1_1	960	964	PF00082	0.447
CLV_PCSK_SKI1_1	992	996	PF00082	0.386
DEG_Nend_UBRbox_2	1	3	PF02207	0.578
DEG_SCF_FBW7_2	300	306	PF00400	0.599
DEG_SPOP_SBC_1	239	243	PF00917	0.792
DEG_SPOP_SBC_1	846	850	PF00917	0.693
DOC_CKS1_1	300	305	PF01111	0.598
DOC_CKS1_1	717	722	PF01111	0.559
DOC_CKS1_1	945	950	PF01111	0.618
DOC_CYCLIN_RxL_1	90	101	PF00134	0.724
DOC_CYCLIN_yClb5_NLxxxL_5	373	379	PF00134	0.618
DOC_CYCLIN_yClb5_NLxxxL_5	962	971	PF00134	0.533
DOC_CYCLIN_yCln2_LP_2	779	782	PF00134	0.591
DOC_CYCLIN_yCln2_LP_2	949	955	PF00134	0.512
DOC_MAPK_DCC_7	795	804	PF00069	0.550
DOC_MAPK_DCC_7	871	880	PF00069	0.593
DOC_MAPK_gen_1	1099	1108	PF00069	0.463
DOC_MAPK_gen_1	337	347	PF00069	0.574
DOC_MAPK_gen_1	430	437	PF00069	0.667
DOC_MAPK_gen_1	583	590	PF00069	0.406
DOC_MAPK_gen_1	621	629	PF00069	0.375
DOC_MAPK_gen_1	90	97	PF00069	0.711
DOC_MAPK_HePTP_8	580	592	PF00069	0.411
DOC_MAPK_JIP1_4	951	957	PF00069	0.576
DOC_MAPK_MEF2A_6	348	357	PF00069	0.490
DOC_MAPK_MEF2A_6	430	437	PF00069	0.667
DOC_MAPK_MEF2A_6	515	522	PF00069	0.356
DOC_MAPK_MEF2A_6	583	592	PF00069	0.406
DOC_MAPK_MEF2A_6	621	629	PF00069	0.429
DOC_MAPK_MEF2A_6	795	804	PF00069	0.579
DOC_MAPK_RevD_3	800	813	PF00069	0.540
DOC_PP1_RVXF_1	381	387	PF00149	0.504
DOC_PP1_RVXF_1	635	642	PF00149	0.535
DOC_PP1_RVXF_1	657	664	PF00149	0.630
DOC_PP2B_LxvP_1	779	782	PF13499	0.591
DOC_PP4_FxxP_1	1017	1020	PF00568	0.517
DOC_USP7_MATH_1	104	108	PF00917	0.723
DOC_USP7_MATH_1	186	190	PF00917	0.655
DOC_USP7_MATH_1	211	215	PF00917	0.739
DOC_USP7_MATH_1	230	234	PF00917	0.608
DOC_USP7_MATH_1	279	283	PF00917	0.810
DOC_USP7_MATH_1	308	312	PF00917	0.623
DOC_USP7_MATH_1	324	328	PF00917	0.730
DOC_USP7_MATH_1	457	461	PF00917	0.656
DOC_USP7_MATH_1	713	717	PF00917	0.805
DOC_USP7_MATH_1	77	81	PF00917	0.639
DOC_USP7_MATH_1	846	850	PF00917	0.722
DOC_USP7_MATH_1	851	855	PF00917	0.659
DOC_USP7_MATH_2	411	417	PF00917	0.545
DOC_WW_Pin1_4	1217	1222	PF00397	0.672
DOC_WW_Pin1_4	299	304	PF00397	0.736
DOC_WW_Pin1_4	34	39	PF00397	0.755
DOC_WW_Pin1_4	444	449	PF00397	0.730
DOC_WW_Pin1_4	542	547	PF00397	0.499
DOC_WW_Pin1_4	716	721	PF00397	0.708
DOC_WW_Pin1_4	723	728	PF00397	0.809
DOC_WW_Pin1_4	773	778	PF00397	0.454
DOC_WW_Pin1_4	786	791	PF00397	0.465
DOC_WW_Pin1_4	944	949	PF00397	0.615
LIG_14-3-3_CanoR_1	1147	1151	PF00244	0.589
LIG_14-3-3_CanoR_1	1152	1158	PF00244	0.590
LIG_14-3-3_CanoR_1	1207	1214	PF00244	0.696
LIG_14-3-3_CanoR_1	250	257	PF00244	0.832
LIG_14-3-3_CanoR_1	383	387	PF00244	0.486
LIG_14-3-3_CanoR_1	401	408	PF00244	0.537
LIG_14-3-3_CanoR_1	640	648	PF00244	0.317
LIG_14-3-3_CanoR_1	707	711	PF00244	0.753
LIG_14-3-3_CanoR_1	840	847	PF00244	0.544
LIG_Actin_WH2_2	567	585	PF00022	0.375
LIG_Actin_WH2_2	625	642	PF00022	0.280
LIG_APCC_ABBA_1	700	705	PF00400	0.729
LIG_APCC_ABBA_1	924	929	PF00400	0.682
LIG_BRCT_BRCA1_1	599	603	PF00533	0.419
LIG_BRCT_BRCA1_1	616	620	PF00533	0.265
LIG_BRCT_BRCA1_1	659	663	PF00533	0.637
LIG_BRCT_BRCA1_1	853	857	PF00533	0.730
LIG_CaM_NSCaTE_8	49	56	PF13499	0.510
LIG_CSL_BTD_1	787	790	PF09270	0.521
LIG_CtBP_PxDLS_1	1058	1062	PF00389	0.465
LIG_CtBP_PxDLS_1	781	785	PF00389	0.598
LIG_FHA_1	1036	1042	PF00498	0.468
LIG_FHA_1	1209	1215	PF00498	0.504
LIG_FHA_1	126	132	PF00498	0.718
LIG_FHA_1	138	144	PF00498	0.691
LIG_FHA_1	204	210	PF00498	0.697
LIG_FHA_1	235	241	PF00498	0.614
LIG_FHA_1	250	256	PF00498	0.709
LIG_FHA_1	268	274	PF00498	0.530
LIG_FHA_1	334	340	PF00498	0.494
LIG_FHA_1	347	353	PF00498	0.502
LIG_FHA_1	359	365	PF00498	0.606
LIG_FHA_1	523	529	PF00498	0.349
LIG_FHA_1	614	620	PF00498	0.499
LIG_FHA_1	640	646	PF00498	0.312
LIG_FHA_1	723	729	PF00498	0.815
LIG_FHA_1	760	766	PF00498	0.623
LIG_FHA_1	774	780	PF00498	0.470
LIG_FHA_1	789	795	PF00498	0.418
LIG_FHA_2	1116	1122	PF00498	0.355
LIG_FHA_2	149	155	PF00498	0.604
LIG_FHA_2	240	246	PF00498	0.764
LIG_FHA_2	358	364	PF00498	0.565
LIG_FHA_2	365	371	PF00498	0.499
LIG_FHA_2	405	411	PF00498	0.495
LIG_FHA_2	440	446	PF00498	0.739
LIG_FHA_2	469	475	PF00498	0.528
LIG_FHA_2	751	757	PF00498	0.528
LIG_FHA_2	758	764	PF00498	0.554
LIG_FHA_2	931	937	PF00498	0.515
LIG_Integrin_isoDGR_2	1028	1030	PF01839	0.570
LIG_Integrin_RGD_1	1179	1181	PF01839	0.420
LIG_IRF3_LxIS_1	538	545	PF10401	0.477
LIG_LIR_Apic_2	1014	1020	PF02991	0.522
LIG_LIR_Gen_1	208	217	PF02991	0.749
LIG_LIR_Gen_1	47	57	PF02991	0.507
LIG_LIR_Gen_1	557	567	PF02991	0.416
LIG_LIR_Gen_1	573	582	PF02991	0.283
LIG_LIR_Gen_1	600	611	PF02991	0.380
LIG_LIR_Gen_1	936	944	PF02991	0.389
LIG_LIR_Nem_3	1009	1013	PF02991	0.490
LIG_LIR_Nem_3	149	155	PF02991	0.516
LIG_LIR_Nem_3	208	213	PF02991	0.751
LIG_LIR_Nem_3	385	389	PF02991	0.542
LIG_LIR_Nem_3	47	52	PF02991	0.677
LIG_LIR_Nem_3	557	562	PF02991	0.416
LIG_LIR_Nem_3	573	578	PF02991	0.283
LIG_LIR_Nem_3	600	606	PF02991	0.407
LIG_LIR_Nem_3	900	904	PF02991	0.537
LIG_LIR_Nem_3	936	941	PF02991	0.392
LIG_LYPXL_S_1	875	879	PF13949	0.581
LIG_MYND_1	777	781	PF01753	0.586
LIG_PCNA_yPIPBox_3	621	633	PF02747	0.280
LIG_PCNA_yPIPBox_3	680	691	PF02747	0.613
LIG_PCNA_yPIPBox_3	973	984	PF02747	0.508
LIG_Pex14_1	788	792	PF04695	0.439
LIG_Pex14_2	620	624	PF04695	0.375
LIG_PTAP_UEV_1	719	724	PF05743	0.524
LIG_PTB_Apo_2	1043	1050	PF02174	0.516
LIG_SH2_CRK	559	563	PF00017	0.429
LIG_SH2_CRK	797	801	PF00017	0.348
LIG_SH2_NCK_1	210	214	PF00017	0.678
LIG_SH2_SRC	210	213	PF00017	0.679
LIG_SH2_SRC	797	800	PF00017	0.346
LIG_SH2_STAP1	1007	1011	PF00017	0.430
LIG_SH2_STAP1	1063	1067	PF00017	0.413
LIG_SH2_STAP1	139	143	PF00017	0.682
LIG_SH2_STAP1	559	563	PF00017	0.429
LIG_SH2_STAT5	1010	1013	PF00017	0.446
LIG_SH2_STAT5	1094	1097	PF00017	0.415
LIG_SH2_STAT5	1165	1168	PF00017	0.590
LIG_SH2_STAT5	139	142	PF00017	0.669
LIG_SH2_STAT5	493	496	PF00017	0.375
LIG_SH2_STAT5	792	795	PF00017	0.487
LIG_SH2_STAT5	814	817	PF00017	0.455
LIG_SH2_STAT5	819	822	PF00017	0.543
LIG_SH2_STAT5	904	907	PF00017	0.591
LIG_SH2_STAT5	993	996	PF00017	0.516
LIG_SH3_3	1017	1023	PF00018	0.478
LIG_SH3_3	1030	1036	PF00018	0.386
LIG_SH3_3	1097	1103	PF00018	0.444
LIG_SH3_3	282	288	PF00018	0.674
LIG_SH3_3	35	41	PF00018	0.590
LIG_SH3_3	381	387	PF00018	0.569
LIG_SH3_3	405	411	PF00018	0.641
LIG_SH3_3	652	658	PF00018	0.343
LIG_SH3_3	71	77	PF00018	0.675
LIG_SH3_3	717	723	PF00018	0.822
LIG_SH3_3	724	730	PF00018	0.794
LIG_SH3_3	793	799	PF00018	0.358
LIG_SH3_3	871	877	PF00018	0.536
LIG_SH3_3	884	890	PF00018	0.363
LIG_SUMO_SIM_anti_2	349	354	PF11976	0.531
LIG_SUMO_SIM_anti_2	560	566	PF11976	0.375
LIG_SUMO_SIM_par_1	466	474	PF11976	0.606
LIG_SUMO_SIM_par_1	560	566	PF11976	0.375
LIG_TRAF2_1	200	203	PF00917	0.677
LIG_UBA3_1	461	468	PF00899	0.702
LIG_UBA3_1	505	510	PF00899	0.429
LIG_WRC_WIRS_1	1108	1113	PF05994	0.537
LIG_WRC_WIRS_1	772	777	PF05994	0.522
MOD_CDK_SPxxK_3	944	951	PF00069	0.613
MOD_CK1_1	1107	1113	PF00069	0.602
MOD_CK1_1	1175	1181	PF00069	0.643
MOD_CK1_1	189	195	PF00069	0.719
MOD_CK1_1	241	247	PF00069	0.564
MOD_CK1_1	346	352	PF00069	0.517
MOD_CK1_1	404	410	PF00069	0.557
MOD_CK1_1	444	450	PF00069	0.717
MOD_CK1_1	568	574	PF00069	0.410
MOD_CK1_1	716	722	PF00069	0.808
MOD_CK1_1	827	833	PF00069	0.748
MOD_CK1_1	839	845	PF00069	0.708
MOD_CK1_1	869	875	PF00069	0.569
MOD_CK1_1	975	981	PF00069	0.500
MOD_CK2_1	197	203	PF00069	0.706
MOD_CK2_1	357	363	PF00069	0.609
MOD_CK2_1	364	370	PF00069	0.538
MOD_CK2_1	439	445	PF00069	0.702
MOD_CK2_1	457	463	PF00069	0.770
MOD_CK2_1	750	756	PF00069	0.497
MOD_CK2_1	757	763	PF00069	0.510
MOD_CK2_1	864	870	PF00069	0.664
MOD_Cter_Amidation	1204	1207	PF01082	0.475
MOD_GlcNHglycan	1200	1203	PF01048	0.714
MOD_GlcNHglycan	133	136	PF01048	0.691
MOD_GlcNHglycan	164	167	PF01048	0.648
MOD_GlcNHglycan	186	189	PF01048	0.655
MOD_GlcNHglycan	281	284	PF01048	0.796
MOD_GlcNHglycan	30	34	PF01048	0.769
MOD_GlcNHglycan	415	418	PF01048	0.588
MOD_GlcNHglycan	448	451	PF01048	0.806
MOD_GlcNHglycan	599	602	PF01048	0.429
MOD_GlcNHglycan	720	723	PF01048	0.787
MOD_GlcNHglycan	79	82	PF01048	0.517
MOD_GlcNHglycan	833	836	PF01048	0.786
MOD_GlcNHglycan	853	856	PF01048	0.409
MOD_GlcNHglycan	996	999	PF01048	0.366
MOD_GSK3_1	1044	1051	PF00069	0.576
MOD_GSK3_1	1107	1114	PF00069	0.536
MOD_GSK3_1	1142	1149	PF00069	0.552
MOD_GSK3_1	127	134	PF00069	0.566
MOD_GSK3_1	137	144	PF00069	0.678
MOD_GSK3_1	230	237	PF00069	0.655
MOD_GSK3_1	239	246	PF00069	0.629
MOD_GSK3_1	453	460	PF00069	0.739
MOD_GSK3_1	523	530	PF00069	0.357
MOD_GSK3_1	701	708	PF00069	0.769
MOD_GSK3_1	718	725	PF00069	0.591
MOD_GSK3_1	823	830	PF00069	0.635
MOD_GSK3_1	847	854	PF00069	0.674
MOD_N-GLC_1	1208	1213	PF02516	0.563
MOD_N-GLC_1	423	428	PF02516	0.563
MOD_N-GLC_1	972	977	PF02516	0.480
MOD_NEK2_1	1081	1086	PF00069	0.448
MOD_NEK2_1	1106	1111	PF00069	0.464
MOD_NEK2_1	1115	1120	PF00069	0.446
MOD_NEK2_1	1125	1130	PF00069	0.446
MOD_NEK2_1	116	121	PF00069	0.711
MOD_NEK2_1	127	132	PF00069	0.682
MOD_NEK2_1	184	189	PF00069	0.583
MOD_NEK2_1	614	619	PF00069	0.413
MOD_NEK2_1	639	644	PF00069	0.520
MOD_NEK2_1	847	852	PF00069	0.669
MOD_NEK2_1	962	967	PF00069	0.492
MOD_NEK2_2	1063	1068	PF00069	0.422
MOD_NEK2_2	343	348	PF00069	0.568
MOD_NEK2_2	534	539	PF00069	0.429
MOD_NEK2_2	713	718	PF00069	0.809
MOD_PIKK_1	1130	1136	PF00454	0.600
MOD_PIKK_1	186	192	PF00454	0.671
MOD_PIKK_1	260	266	PF00454	0.531
MOD_PIKK_1	528	534	PF00454	0.429
MOD_PK_1	1000	1006	PF00069	0.588
MOD_PK_1	736	742	PF00069	0.652
MOD_PKA_1	1153	1159	PF00069	0.606
MOD_PKA_1	1207	1213	PF00069	0.703
MOD_PKA_1	316	322	PF00069	0.670
MOD_PKA_1	736	742	PF00069	0.652
MOD_PKA_2	1146	1152	PF00069	0.669
MOD_PKA_2	1198	1204	PF00069	0.705
MOD_PKA_2	1207	1213	PF00069	0.632
MOD_PKA_2	249	255	PF00069	0.793
MOD_PKA_2	316	322	PF00069	0.670
MOD_PKA_2	358	364	PF00069	0.594
MOD_PKA_2	382	388	PF00069	0.532
MOD_PKA_2	413	419	PF00069	0.549
MOD_PKA_2	639	645	PF00069	0.326
MOD_PKA_2	706	712	PF00069	0.790
MOD_PKA_2	736	742	PF00069	0.733
MOD_PKA_2	823	829	PF00069	0.756
MOD_PKA_2	831	837	PF00069	0.654
MOD_PKA_2	839	845	PF00069	0.507
MOD_PKA_2	89	95	PF00069	0.503
MOD_PKB_1	232	240	PF00069	0.608
MOD_Plk_1	1000	1006	PF00069	0.571
MOD_Plk_1	1081	1087	PF00069	0.453
MOD_Plk_1	1125	1131	PF00069	0.445
MOD_Plk_1	148	154	PF00069	0.662
MOD_Plk_1	196	202	PF00069	0.793
MOD_Plk_1	404	410	PF00069	0.557
MOD_Plk_1	423	429	PF00069	0.553
MOD_Plk_1	554	560	PF00069	0.402
MOD_Plk_1	565	571	PF00069	0.334
MOD_Plk_1	713	719	PF00069	0.810
MOD_Plk_1	869	875	PF00069	0.545
MOD_Plk_1	936	942	PF00069	0.542
MOD_Plk_2-3	197	203	PF00069	0.782
MOD_Plk_2-3	555	561	PF00069	0.429
MOD_Plk_2-3	58	64	PF00069	0.628
MOD_Plk_4	1000	1006	PF00069	0.588
MOD_Plk_4	1071	1077	PF00069	0.471
MOD_Plk_4	1111	1117	PF00069	0.527
MOD_Plk_4	1153	1159	PF00069	0.632
MOD_Plk_4	457	463	PF00069	0.710
MOD_Plk_4	489	495	PF00069	0.375
MOD_Plk_4	500	506	PF00069	0.375
MOD_Plk_4	565	571	PF00069	0.354
MOD_Plk_4	615	621	PF00069	0.477
MOD_Plk_4	628	634	PF00069	0.372
MOD_Plk_4	780	786	PF00069	0.518
MOD_Plk_4	788	794	PF00069	0.392
MOD_Plk_4	975	981	PF00069	0.500
MOD_ProDKin_1	1217	1223	PF00069	0.674
MOD_ProDKin_1	299	305	PF00069	0.735
MOD_ProDKin_1	34	40	PF00069	0.755
MOD_ProDKin_1	444	450	PF00069	0.732
MOD_ProDKin_1	542	548	PF00069	0.499
MOD_ProDKin_1	716	722	PF00069	0.709
MOD_ProDKin_1	723	729	PF00069	0.808
MOD_ProDKin_1	773	779	PF00069	0.459
MOD_ProDKin_1	786	792	PF00069	0.460
MOD_ProDKin_1	944	950	PF00069	0.611
MOD_SUMO_for_1	1011	1014	PF00179	0.520
MOD_SUMO_rev_2	1185	1194	PF00179	0.637
MOD_SUMO_rev_2	460	470	PF00179	0.695
TRG_DiLeu_BaEn_1	326	331	PF01217	0.607
TRG_DiLeu_BaEn_2	896	902	PF01217	0.341
TRG_DiLeu_BaEn_4	196	202	PF01217	0.723
TRG_DiLeu_BaLyEn_6	1184	1189	PF01217	0.539
TRG_DiLeu_BaLyEn_6	398	403	PF01217	0.533
TRG_DiLeu_BaLyEn_6	610	615	PF01217	0.429
TRG_ENDOCYTIC_2	1094	1097	PF00928	0.415
TRG_ENDOCYTIC_2	210	213	PF00928	0.679
TRG_ENDOCYTIC_2	332	335	PF00928	0.478
TRG_ENDOCYTIC_2	396	399	PF00928	0.481
TRG_ENDOCYTIC_2	559	562	PF00928	0.429
TRG_ENDOCYTIC_2	876	879	PF00928	0.461
TRG_ER_diArg_1	1146	1148	PF00400	0.579
TRG_ER_diArg_1	1158	1161	PF00400	0.631
TRG_ER_diArg_1	225	228	PF00400	0.631
TRG_ER_diArg_1	337	339	PF00400	0.596
TRG_ER_diArg_1	582	584	PF00400	0.375
TRG_ER_diArg_1	620	622	PF00400	0.375
TRG_ER_diArg_1	648	650	PF00400	0.458
TRG_ER_diArg_1	734	737	PF00400	0.713
TRG_ER_diArg_1	811	813	PF00400	0.524
TRG_ER_diArg_1	885	888	PF00400	0.445
TRG_ER_diArg_1	90	93	PF00400	0.505
TRG_ER_diArg_1	919	922	PF00400	0.543
TRG_NES_CRM1_1	1071	1082	PF08389	0.453
TRG_NLS_Bipartite_1	218	235	PF00514	0.816
TRG_NLS_MonoExtC_3	227	232	PF00514	0.827
TRG_NLS_MonoExtN_4	1152	1157	PF00514	0.633
TRG_NLS_MonoExtN_4	1204	1210	PF00514	0.689
TRG_NLS_MonoExtN_4	225	232	PF00514	0.828
TRG_Pf-PMV_PEXEL_1	1187	1191	PF00026	0.541
TRG_Pf-PMV_PEXEL_1	17	21	PF00026	0.755
TRG_Pf-PMV_PEXEL_1	25	30	PF00026	0.651
TRG_Pf-PMV_PEXEL_1	373	378	PF00026	0.558
TRG_Pf-PMV_PEXEL_1	401	405	PF00026	0.551
TRG_Pf-PMV_PEXEL_1	507	511	PF00026	0.429
TRG_Pf-PMV_PEXEL_1	572	576	PF00026	0.429
TRG_Pf-PMV_PEXEL_1	93	98	PF00026	0.724
TRG_Pf-PMV_PEXEL_1	983	988	PF00026	0.529

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIS5	Leptomonas seymouri	63%	90%
A0A3R7MZY3	Trypanosoma rangeli	44%	100%
A0A3S7WRJ2	Leishmania donovani	90%	100%
A4H6E9	Leishmania braziliensis	79%	97%
A4HUU3	Leishmania infantum	90%	81%
Q4QH48	Leishmania major	89%	100%