Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9ANH5_LEIMU

TriTrypDb:

LmxM.11.0290

Length:

478

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ANH5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANH5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	245	249	PF00656	0.581
CLV_C14_Caspase3-7	28	32	PF00656	0.426
CLV_NRD_NRD_1	150	152	PF00675	0.554
CLV_NRD_NRD_1	225	227	PF00675	0.654
CLV_NRD_NRD_1	344	346	PF00675	0.734
CLV_NRD_NRD_1	38	40	PF00675	0.610
CLV_NRD_NRD_1	416	418	PF00675	0.544
CLV_NRD_NRD_1	42	44	PF00675	0.648
CLV_NRD_NRD_1	464	466	PF00675	0.587
CLV_NRD_NRD_1	68	70	PF00675	0.709
CLV_PCSK_FUR_1	223	227	PF00082	0.661
CLV_PCSK_FUR_1	352	356	PF00082	0.723
CLV_PCSK_FUR_1	39	43	PF00082	0.694
CLV_PCSK_KEX2_1	225	227	PF00082	0.644
CLV_PCSK_KEX2_1	344	346	PF00082	0.766
CLV_PCSK_KEX2_1	354	356	PF00082	0.688
CLV_PCSK_KEX2_1	38	40	PF00082	0.706
CLV_PCSK_KEX2_1	41	43	PF00082	0.651
CLV_PCSK_KEX2_1	416	418	PF00082	0.544
CLV_PCSK_KEX2_1	68	70	PF00082	0.709
CLV_PCSK_PC1ET2_1	354	356	PF00082	0.791
CLV_PCSK_PC7_1	34	40	PF00082	0.522
CLV_PCSK_PC7_1	340	346	PF00082	0.727
CLV_PCSK_SKI1_1	27	31	PF00082	0.522
CLV_PCSK_SKI1_1	309	313	PF00082	0.669
CLV_PCSK_SKI1_1	449	453	PF00082	0.613
CLV_Separin_Metazoa	446	450	PF03568	0.602
DEG_Nend_Nbox_1	1	3	PF02207	0.556
DEG_SPOP_SBC_1	397	401	PF00917	0.531
DOC_CKS1_1	237	242	PF01111	0.756
DOC_CKS1_1	422	427	PF01111	0.630
DOC_CKS1_1	80	85	PF01111	0.586
DOC_CYCLIN_RxL_1	306	315	PF00134	0.758
DOC_CYCLIN_yCln2_LP_2	163	169	PF00134	0.491
DOC_MAPK_MEF2A_6	3	12	PF00069	0.583
DOC_PP1_RVXF_1	239	245	PF00149	0.648
DOC_PP2B_LxvP_1	95	98	PF13499	0.771
DOC_PP4_FxxP_1	237	240	PF00568	0.761
DOC_USP7_MATH_1	100	104	PF00917	0.651
DOC_USP7_MATH_1	134	138	PF00917	0.782
DOC_USP7_MATH_1	146	150	PF00917	0.630
DOC_USP7_MATH_1	29	33	PF00917	0.530
DOC_USP7_MATH_1	442	446	PF00917	0.628
DOC_WW_Pin1_4	103	108	PF00397	0.771
DOC_WW_Pin1_4	130	135	PF00397	0.730
DOC_WW_Pin1_4	142	147	PF00397	0.632
DOC_WW_Pin1_4	181	186	PF00397	0.642
DOC_WW_Pin1_4	236	241	PF00397	0.826
DOC_WW_Pin1_4	292	297	PF00397	0.776
DOC_WW_Pin1_4	345	350	PF00397	0.562
DOC_WW_Pin1_4	359	364	PF00397	0.537
DOC_WW_Pin1_4	421	426	PF00397	0.619
DOC_WW_Pin1_4	79	84	PF00397	0.567
DOC_WW_Pin1_4	96	101	PF00397	0.702
LIG_14-3-3_CanoR_1	214	221	PF00244	0.705
LIG_14-3-3_CanoR_1	223	231	PF00244	0.566
LIG_14-3-3_CanoR_1	449	454	PF00244	0.640
LIG_14-3-3_CanoR_1	75	83	PF00244	0.569
LIG_14-3-3_CanoR_1	92	98	PF00244	0.636
LIG_Clathr_ClatBox_1	450	454	PF01394	0.539
LIG_FHA_1	100	106	PF00498	0.725
LIG_FHA_1	226	232	PF00498	0.684
LIG_FHA_1	237	243	PF00498	0.696
LIG_FHA_1	398	404	PF00498	0.647
LIG_FHA_2	26	32	PF00498	0.437
LIG_FHA_2	399	405	PF00498	0.539
LIG_FHA_2	85	91	PF00498	0.772
LIG_LIR_Gen_1	382	392	PF02991	0.653
LIG_LIR_Nem_3	164	168	PF02991	0.489
LIG_LIR_Nem_3	382	387	PF02991	0.662
LIG_SH2_CRK	384	388	PF00017	0.650
LIG_SH2_STAP1	384	388	PF00017	0.695
LIG_SH2_STAT5	25	28	PF00017	0.421
LIG_SH2_STAT5	252	255	PF00017	0.591
LIG_SH3_1	419	425	PF00018	0.630
LIG_SH3_2	80	85	PF14604	0.545
LIG_SH3_3	125	131	PF00018	0.764
LIG_SH3_3	140	146	PF00018	0.565
LIG_SH3_3	293	299	PF00018	0.734
LIG_SH3_3	343	349	PF00018	0.837
LIG_SH3_3	419	425	PF00018	0.653
LIG_SH3_3	77	83	PF00018	0.618
LIG_SH3_4	152	159	PF00018	0.597
LIG_TRAF2_1	210	213	PF00917	0.671
MOD_CDK_SPK_2	236	241	PF00069	0.700
MOD_CDK_SPK_2	292	297	PF00069	0.537
MOD_CDK_SPxK_1	79	85	PF00069	0.587
MOD_CDK_SPxxK_3	236	243	PF00069	0.677
MOD_CDK_SPxxK_3	345	352	PF00069	0.550
MOD_CDK_SPxxK_3	79	86	PF00069	0.546
MOD_CK1_1	133	139	PF00069	0.778
MOD_CK1_1	173	179	PF00069	0.717
MOD_CK1_1	194	200	PF00069	0.665
MOD_CK1_1	207	213	PF00069	0.663
MOD_CK1_1	216	222	PF00069	0.583
MOD_CK1_1	259	265	PF00069	0.692
MOD_CK1_1	362	368	PF00069	0.571
MOD_CK1_1	62	68	PF00069	0.648
MOD_CK1_1	99	105	PF00069	0.802
MOD_CK2_1	207	213	PF00069	0.812
MOD_CK2_1	259	265	PF00069	0.718
MOD_CK2_1	322	328	PF00069	0.784
MOD_CK2_1	398	404	PF00069	0.607
MOD_Cter_Amidation	66	69	PF01082	0.619
MOD_DYRK1A_RPxSP_1	345	349	PF00069	0.554
MOD_GlcNHglycan	136	139	PF01048	0.725
MOD_GlcNHglycan	140	143	PF01048	0.762
MOD_GlcNHglycan	148	151	PF01048	0.724
MOD_GlcNHglycan	153	156	PF01048	0.621
MOD_GlcNHglycan	185	188	PF01048	0.643
MOD_GlcNHglycan	193	196	PF01048	0.702
MOD_GlcNHglycan	324	327	PF01048	0.713
MOD_GlcNHglycan	330	333	PF01048	0.739
MOD_GlcNHglycan	437	441	PF01048	0.570
MOD_GSK3_1	130	137	PF00069	0.775
MOD_GSK3_1	138	145	PF00069	0.674
MOD_GSK3_1	203	210	PF00069	0.638
MOD_GSK3_1	212	219	PF00069	0.626
MOD_GSK3_1	225	232	PF00069	0.705
MOD_GSK3_1	25	32	PF00069	0.425
MOD_GSK3_1	255	262	PF00069	0.723
MOD_GSK3_1	362	369	PF00069	0.674
MOD_GSK3_1	417	424	PF00069	0.640
MOD_GSK3_1	438	445	PF00069	0.654
MOD_GSK3_1	449	456	PF00069	0.560
MOD_GSK3_1	57	64	PF00069	0.747
MOD_GSK3_1	84	91	PF00069	0.685
MOD_GSK3_1	96	103	PF00069	0.583
MOD_N-GLC_1	217	222	PF02516	0.521
MOD_N-GLC_1	359	364	PF02516	0.550
MOD_NEK2_1	203	208	PF00069	0.665
MOD_NEK2_1	30	35	PF00069	0.524
MOD_NEK2_1	396	401	PF00069	0.597
MOD_NEK2_1	453	458	PF00069	0.541
MOD_NEK2_1	473	478	PF00069	0.550
MOD_NEK2_1	93	98	PF00069	0.639
MOD_OFUCOSY	170	175	PF10250	0.487
MOD_PIKK_1	100	106	PF00454	0.530
MOD_PIKK_1	431	437	PF00454	0.579
MOD_PKA_1	151	157	PF00069	0.543
MOD_PKA_1	225	231	PF00069	0.649
MOD_PKA_2	213	219	PF00069	0.741
MOD_PKA_2	224	230	PF00069	0.740
MOD_PKA_2	430	436	PF00069	0.707
MOD_PKA_2	74	80	PF00069	0.551
MOD_PKA_2	93	99	PF00069	0.613
MOD_PKB_1	223	231	PF00069	0.657
MOD_Plk_1	124	130	PF00069	0.679
MOD_Plk_1	217	223	PF00069	0.522
MOD_Plk_1	88	94	PF00069	0.610
MOD_Plk_4	124	130	PF00069	0.671
MOD_Plk_4	204	210	PF00069	0.632
MOD_Plk_4	248	254	PF00069	0.589
MOD_Plk_4	398	404	PF00069	0.647
MOD_ProDKin_1	103	109	PF00069	0.772
MOD_ProDKin_1	130	136	PF00069	0.731
MOD_ProDKin_1	142	148	PF00069	0.635
MOD_ProDKin_1	181	187	PF00069	0.644
MOD_ProDKin_1	236	242	PF00069	0.820
MOD_ProDKin_1	292	298	PF00069	0.774
MOD_ProDKin_1	345	351	PF00069	0.562
MOD_ProDKin_1	359	365	PF00069	0.535
MOD_ProDKin_1	421	427	PF00069	0.621
MOD_ProDKin_1	79	85	PF00069	0.565
MOD_ProDKin_1	96	102	PF00069	0.698
MOD_SUMO_rev_2	399	408	PF00179	0.481
MOD_SUMO_rev_2	462	468	PF00179	0.760
TRG_DiLeu_BaLyEn_6	4	9	PF01217	0.646
TRG_ENDOCYTIC_2	384	387	PF00928	0.653
TRG_ER_diArg_1	223	226	PF00400	0.726
TRG_ER_diArg_1	344	346	PF00400	0.734
TRG_ER_diArg_1	38	41	PF00400	0.694
TRG_ER_diArg_1	92	95	PF00400	0.626
TRG_Pf-PMV_PEXEL_1	7	11	PF00026	0.641

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HV85	Leptomonas seymouri	25%	100%
A0A3S7WRI4	Leishmania donovani	78%	100%
A4H9S9	Leishmania braziliensis	57%	100%
A4HUU0	Leishmania infantum	78%	100%
Q4QH51	Leishmania major	76%	99%