Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ANG6_LEIMU

TriTrypDb:

LmxM.11.0200

Length:

184

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ANG6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANG6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	43	47	PF00656	0.628
CLV_NRD_NRD_1	158	160	PF00675	0.515
CLV_NRD_NRD_1	164	166	PF00675	0.541
CLV_NRD_NRD_1	90	92	PF00675	0.633
CLV_PCSK_KEX2_1	158	160	PF00082	0.515
CLV_PCSK_KEX2_1	164	166	PF00082	0.541
CLV_PCSK_KEX2_1	33	35	PF00082	0.399
CLV_PCSK_KEX2_1	90	92	PF00082	0.580
CLV_PCSK_PC1ET2_1	33	35	PF00082	0.399
CLV_PCSK_SKI1_1	150	154	PF00082	0.634
CLV_PCSK_SKI1_1	90	94	PF00082	0.520
DEG_SPOP_SBC_1	37	41	PF00917	0.630
DOC_CYCLIN_RxL_1	87	94	PF00134	0.466
DOC_MAPK_gen_1	142	151	PF00069	0.624
DOC_MAPK_HePTP_8	141	153	PF00069	0.627
DOC_MAPK_MEF2A_6	144	153	PF00069	0.626
DOC_USP7_MATH_1	10	14	PF00917	0.743
DOC_USP7_MATH_1	111	115	PF00917	0.689
DOC_USP7_MATH_1	37	41	PF00917	0.610
DOC_USP7_MATH_1	59	63	PF00917	0.705
DOC_WW_Pin1_4	107	112	PF00397	0.794
DOC_WW_Pin1_4	13	18	PF00397	0.643
DOC_WW_Pin1_4	38	43	PF00397	0.748
DOC_WW_Pin1_4	46	51	PF00397	0.700
LIG_BIR_II_1	1	5	PF00653	0.746
LIG_CaM_IQ_9	134	149	PF13499	0.525
LIG_FHA_1	53	59	PF00498	0.764
LIG_FHA_1	73	79	PF00498	0.543
LIG_FHA_2	119	125	PF00498	0.678
LIG_FHA_2	126	132	PF00498	0.584
LIG_LIR_Nem_3	87	92	PF02991	0.625
LIG_PDZ_Class_2	179	184	PF00595	0.581
LIG_SH2_CRK	89	93	PF00017	0.636
LIG_SH3_3	16	22	PF00018	0.600
LIG_SUMO_SIM_anti_2	75	80	PF11976	0.592
LIG_TRAF2_1	84	87	PF00917	0.564
MOD_CDK_SPxxK_3	46	53	PF00069	0.541
MOD_CK1_1	125	131	PF00069	0.497
MOD_CK1_1	13	19	PF00069	0.703
MOD_CK1_1	2	8	PF00069	0.628
MOD_CK1_1	40	46	PF00069	0.645
MOD_CK2_1	118	124	PF00069	0.517
MOD_CK2_1	125	131	PF00069	0.475
MOD_CK2_1	51	57	PF00069	0.794
MOD_GlcNHglycan	103	106	PF01048	0.742
MOD_GlcNHglycan	111	114	PF01048	0.577
MOD_GlcNHglycan	12	15	PF01048	0.704
MOD_GlcNHglycan	175	178	PF01048	0.572
MOD_GlcNHglycan	7	10	PF01048	0.651
MOD_GSK3_1	107	114	PF00069	0.656
MOD_GSK3_1	118	125	PF00069	0.583
MOD_GSK3_1	36	43	PF00069	0.754
MOD_GSK3_1	68	75	PF00069	0.665
MOD_NEK2_1	122	127	PF00069	0.511
MOD_NEK2_1	175	180	PF00069	0.627
MOD_NEK2_1	51	56	PF00069	0.739
MOD_PIKK_1	99	105	PF00454	0.767
MOD_PKA_2	52	58	PF00069	0.551
MOD_Plk_1	2	8	PF00069	0.741
MOD_Plk_4	122	128	PF00069	0.651
MOD_ProDKin_1	107	113	PF00069	0.794
MOD_ProDKin_1	13	19	PF00069	0.699
MOD_ProDKin_1	38	44	PF00069	0.755
MOD_ProDKin_1	46	52	PF00069	0.703
MOD_SUMO_for_1	169	172	PF00179	0.538
TRG_DiLeu_BaLyEn_6	88	93	PF01217	0.568
TRG_ENDOCYTIC_2	89	92	PF00928	0.636
TRG_ER_diArg_1	157	159	PF00400	0.525
TRG_ER_diArg_1	89	91	PF00400	0.644
TRG_Pf-PMV_PEXEL_1	56	60	PF00026	0.777
TRG_Pf-PMV_PEXEL_1	90	94	PF00026	0.473

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4P1	Leptomonas seymouri	45%	100%
A0A3S7WRH9	Leishmania donovani	85%	100%
A4H9T8	Leishmania braziliensis	75%	100%
A4HUT2	Leishmania infantum	85%	100%
Q4QH60	Leishmania major	88%	100%