Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ANG1_LEIMU

TriTrypDb:

LmxM.11.0150

Length:

867

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 2
Forrest at al. (procyclic)	no	yes: 2
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ANG1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANG1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	121	125	PF00656	0.765
CLV_C14_Caspase3-7	144	148	PF00656	0.634
CLV_C14_Caspase3-7	509	513	PF00656	0.668
CLV_NRD_NRD_1	176	178	PF00675	0.823
CLV_NRD_NRD_1	180	182	PF00675	0.780
CLV_NRD_NRD_1	246	248	PF00675	0.702
CLV_NRD_NRD_1	282	284	PF00675	0.628
CLV_NRD_NRD_1	45	47	PF00675	0.603
CLV_NRD_NRD_1	489	491	PF00675	0.805
CLV_NRD_NRD_1	498	500	PF00675	0.695
CLV_NRD_NRD_1	60	62	PF00675	0.616
CLV_NRD_NRD_1	601	603	PF00675	0.672
CLV_NRD_NRD_1	87	89	PF00675	0.847
CLV_NRD_NRD_1	97	99	PF00675	0.677
CLV_PCSK_FUR_1	496	500	PF00082	0.762
CLV_PCSK_KEX2_1	176	178	PF00082	0.745
CLV_PCSK_KEX2_1	237	239	PF00082	0.673
CLV_PCSK_KEX2_1	246	248	PF00082	0.553
CLV_PCSK_KEX2_1	282	284	PF00082	0.628
CLV_PCSK_KEX2_1	45	47	PF00082	0.851
CLV_PCSK_KEX2_1	488	490	PF00082	0.804
CLV_PCSK_KEX2_1	498	500	PF00082	0.682
CLV_PCSK_KEX2_1	526	528	PF00082	0.859
CLV_PCSK_KEX2_1	60	62	PF00082	0.616
CLV_PCSK_KEX2_1	87	89	PF00082	0.847
CLV_PCSK_KEX2_1	97	99	PF00082	0.677
CLV_PCSK_PC1ET2_1	237	239	PF00082	0.673
CLV_PCSK_PC1ET2_1	526	528	PF00082	0.781
CLV_PCSK_PC1ET2_1	87	89	PF00082	0.847
CLV_PCSK_SKI1_1	168	172	PF00082	0.578
CLV_PCSK_SKI1_1	217	221	PF00082	0.659
CLV_PCSK_SKI1_1	283	287	PF00082	0.473
CLV_PCSK_SKI1_1	473	477	PF00082	0.842
CLV_PCSK_SKI1_1	489	493	PF00082	0.542
CLV_PCSK_SKI1_1	628	632	PF00082	0.721
CLV_PCSK_SKI1_1	837	841	PF00082	0.727
DEG_Nend_UBRbox_2	1	3	PF02207	0.807
DEG_SPOP_SBC_1	117	121	PF00917	0.804
DEG_SPOP_SBC_1	126	130	PF00917	0.742
DEG_SPOP_SBC_1	153	157	PF00917	0.839
DOC_CKS1_1	400	405	PF01111	0.846
DOC_CKS1_1	646	651	PF01111	0.544
DOC_CKS1_1	857	862	PF01111	0.734
DOC_CYCLIN_RxL_1	564	574	PF00134	0.665
DOC_CYCLIN_yClb1_LxF_4	835	840	PF00134	0.556
DOC_CYCLIN_yCln2_LP_2	554	557	PF00134	0.837
DOC_MAPK_gen_1	488	495	PF00069	0.745
DOC_MAPK_gen_1	673	682	PF00069	0.539
DOC_MAPK_gen_1	705	714	PF00069	0.837
DOC_MAPK_MEF2A_6	488	495	PF00069	0.733
DOC_PP1_RVXF_1	567	574	PF00149	0.754
DOC_PP1_RVXF_1	835	841	PF00149	0.760
DOC_PP2B_LxvP_1	55	58	PF13499	0.558
DOC_PP2B_LxvP_1	554	557	PF13499	0.837
DOC_PP2B_LxvP_1	73	76	PF13499	0.495
DOC_PP2B_LxvP_1	744	747	PF13499	0.804
DOC_PP4_FxxP_1	285	288	PF00568	0.489
DOC_PP4_FxxP_1	573	576	PF00568	0.837
DOC_PP4_FxxP_1	763	766	PF00568	0.805
DOC_PP4_FxxP_1	840	843	PF00568	0.769
DOC_PP4_MxPP_1	774	777	PF00568	0.824
DOC_SPAK_OSR1_1	253	257	PF12202	0.654
DOC_USP7_MATH_1	126	130	PF00917	0.630
DOC_USP7_MATH_1	153	157	PF00917	0.703
DOC_USP7_MATH_1	34	38	PF00917	0.736
DOC_USP7_MATH_1	365	369	PF00917	0.779
DOC_USP7_MATH_1	469	473	PF00917	0.845
DOC_USP7_MATH_1	474	478	PF00917	0.757
DOC_USP7_MATH_1	536	540	PF00917	0.792
DOC_USP7_MATH_1	601	605	PF00917	0.674
DOC_USP7_MATH_1	726	730	PF00917	0.665
DOC_USP7_MATH_1	78	82	PF00917	0.752
DOC_USP7_UBL2_3	526	530	PF12436	0.568
DOC_USP7_UBL2_3	603	607	PF12436	0.580
DOC_USP7_UBL2_3	87	91	PF12436	0.849
DOC_WW_Pin1_4	271	276	PF00397	0.741
DOC_WW_Pin1_4	323	328	PF00397	0.782
DOC_WW_Pin1_4	354	359	PF00397	0.694
DOC_WW_Pin1_4	395	400	PF00397	0.685
DOC_WW_Pin1_4	49	54	PF00397	0.757
DOC_WW_Pin1_4	519	524	PF00397	0.795
DOC_WW_Pin1_4	530	535	PF00397	0.730
DOC_WW_Pin1_4	557	562	PF00397	0.836
DOC_WW_Pin1_4	609	614	PF00397	0.735
DOC_WW_Pin1_4	618	623	PF00397	0.749
DOC_WW_Pin1_4	637	642	PF00397	0.641
DOC_WW_Pin1_4	645	650	PF00397	0.651
DOC_WW_Pin1_4	687	692	PF00397	0.777
DOC_WW_Pin1_4	71	76	PF00397	0.592
DOC_WW_Pin1_4	733	738	PF00397	0.783
DOC_WW_Pin1_4	798	803	PF00397	0.441
DOC_WW_Pin1_4	856	861	PF00397	0.734
LIG_14-3-3_CanoR_1	103	108	PF00244	0.851
LIG_14-3-3_CanoR_1	189	195	PF00244	0.529
LIG_14-3-3_CanoR_1	246	251	PF00244	0.715
LIG_14-3-3_CanoR_1	282	286	PF00244	0.622
LIG_14-3-3_CanoR_1	374	383	PF00244	0.751
LIG_14-3-3_CanoR_1	479	483	PF00244	0.666
LIG_14-3-3_CanoR_1	60	64	PF00244	0.768
LIG_14-3-3_CanoR_1	708	713	PF00244	0.835
LIG_BRCT_BRCA1_1	103	107	PF00533	0.850
LIG_BRCT_BRCA1_1	810	814	PF00533	0.696
LIG_EVH1_1	763	767	PF00568	0.732
LIG_FHA_1	272	278	PF00498	0.583
LIG_FHA_1	329	335	PF00498	0.543
LIG_FHA_1	355	361	PF00498	0.783
LIG_FHA_1	642	648	PF00498	0.739
LIG_FHA_1	799	805	PF00498	0.447
LIG_FHA_2	374	380	PF00498	0.702
LIG_FHA_2	400	406	PF00498	0.773
LIG_FHA_2	479	485	PF00498	0.729
LIG_FHA_2	509	515	PF00498	0.841
LIG_FHA_2	670	676	PF00498	0.541
LIG_LIR_Apic_2	284	288	PF02991	0.578
LIG_LIR_Apic_2	37	42	PF02991	0.739
LIG_LIR_Apic_2	636	641	PF02991	0.779
LIG_LIR_Apic_2	762	766	PF02991	0.810
LIG_LIR_Gen_1	481	486	PF02991	0.631
LIG_LIR_Gen_1	808	818	PF02991	0.638
LIG_LIR_LC3C_4	756	761	PF02991	0.749
LIG_LIR_Nem_3	481	485	PF02991	0.637
LIG_LIR_Nem_3	629	633	PF02991	0.613
LIG_LIR_Nem_3	677	682	PF02991	0.755
LIG_LIR_Nem_3	811	817	PF02991	0.636
LIG_MAD2	321	329	PF02301	0.725
LIG_MAD2	827	835	PF02301	0.510
LIG_MYND_1	71	75	PF01753	0.550
LIG_Pex14_1	31	35	PF04695	0.734
LIG_Pex14_1	810	814	PF04695	0.712
LIG_Pex14_2	806	810	PF04695	0.691
LIG_Pex14_2	814	818	PF04695	0.621
LIG_PROFILIN_1	64	70	PF00235	0.805
LIG_PTAP_UEV_1	845	850	PF05743	0.532
LIG_Rb_LxCxE_1	629	648	PF01857	0.778
LIG_SH2_CRK	39	43	PF00017	0.740
LIG_SH2_GRB2like	47	50	PF00017	0.853
LIG_SH2_NCK_1	39	43	PF00017	0.740
LIG_SH2_PTP2	638	641	PF00017	0.792
LIG_SH2_SRC	39	42	PF00017	0.757
LIG_SH2_STAP1	27	31	PF00017	0.690
LIG_SH2_STAT3	23	26	PF00017	0.738
LIG_SH2_STAT5	302	305	PF00017	0.762
LIG_SH2_STAT5	47	50	PF00017	0.736
LIG_SH2_STAT5	638	641	PF00017	0.792
LIG_SH2_STAT5	679	682	PF00017	0.754
LIG_SH3_1	397	403	PF00018	0.847
LIG_SH3_1	61	67	PF00018	0.825
LIG_SH3_2	41	46	PF14604	0.828
LIG_SH3_2	748	753	PF14604	0.546
LIG_SH3_2	75	80	PF14604	0.550
LIG_SH3_3	335	341	PF00018	0.846
LIG_SH3_3	342	348	PF00018	0.743
LIG_SH3_3	38	44	PF00018	0.819
LIG_SH3_3	397	403	PF00018	0.847
LIG_SH3_3	468	474	PF00018	0.611
LIG_SH3_3	529	535	PF00018	0.675
LIG_SH3_3	555	561	PF00018	0.805
LIG_SH3_3	61	67	PF00018	0.697
LIG_SH3_3	643	649	PF00018	0.664
LIG_SH3_3	686	692	PF00018	0.750
LIG_SH3_3	69	75	PF00018	0.552
LIG_SH3_3	735	741	PF00018	0.568
LIG_SH3_3	745	751	PF00018	0.666
LIG_SH3_3	758	764	PF00018	0.726
LIG_SH3_3	840	846	PF00018	0.711
LIG_SH3_3	847	853	PF00018	0.787
LIG_SUMO_SIM_par_1	266	274	PF11976	0.738
LIG_SUMO_SIM_par_1	330	337	PF11976	0.627
LIG_TRAF2_1	276	279	PF00917	0.735
LIG_TYR_ITIM	480	485	PF00017	0.541
LIG_WW_3	42	46	PF00397	0.755
LIG_WW_3	599	603	PF00397	0.671
MOD_CDK_SPxxK_3	399	406	PF00069	0.751
MOD_CDK_SPxxK_3	519	526	PF00069	0.752
MOD_CDK_SPxxK_3	687	694	PF00069	0.545
MOD_CK1_1	108	114	PF00069	0.821
MOD_CK1_1	115	121	PF00069	0.658
MOD_CK1_1	122	128	PF00069	0.545
MOD_CK1_1	129	135	PF00069	0.572
MOD_CK1_1	137	143	PF00069	0.568
MOD_CK1_1	145	151	PF00069	0.565
MOD_CK1_1	152	158	PF00069	0.746
MOD_CK1_1	159	165	PF00069	0.626
MOD_CK1_1	169	175	PF00069	0.510
MOD_CK1_1	291	297	PF00069	0.786
MOD_CK1_1	343	349	PF00069	0.842
MOD_CK1_1	354	360	PF00069	0.616
MOD_CK1_1	398	404	PF00069	0.553
MOD_CK1_1	559	565	PF00069	0.826
MOD_CK1_1	59	65	PF00069	0.727
MOD_CK1_1	690	696	PF00069	0.772
MOD_CK1_1	729	735	PF00069	0.564
MOD_CK1_1	794	800	PF00069	0.652
MOD_CK1_1	808	814	PF00069	0.480
MOD_CK2_1	143	149	PF00069	0.850
MOD_CK2_1	169	175	PF00069	0.840
MOD_CK2_1	373	379	PF00069	0.704
MOD_CK2_1	478	484	PF00069	0.663
MOD_CK2_1	512	518	PF00069	0.823
MOD_CK2_1	519	525	PF00069	0.774
MOD_CK2_1	536	542	PF00069	0.565
MOD_CK2_1	623	629	PF00069	0.667
MOD_CK2_1	669	675	PF00069	0.538
MOD_CK2_1	694	700	PF00069	0.559
MOD_CK2_1	729	735	PF00069	0.651
MOD_CK2_1	779	785	PF00069	0.800
MOD_Cter_Amidation	822	825	PF01082	0.674
MOD_GlcNHglycan	103	106	PF01048	0.848
MOD_GlcNHglycan	107	110	PF01048	0.788
MOD_GlcNHglycan	124	127	PF01048	0.638
MOD_GlcNHglycan	139	142	PF01048	0.742
MOD_GlcNHglycan	149	152	PF01048	0.666
MOD_GlcNHglycan	158	161	PF01048	0.590
MOD_GlcNHglycan	290	293	PF01048	0.784
MOD_GlcNHglycan	345	348	PF01048	0.852
MOD_GlcNHglycan	353	356	PF01048	0.698
MOD_GlcNHglycan	376	379	PF01048	0.693
MOD_GlcNHglycan	476	479	PF01048	0.552
MOD_GlcNHglycan	514	517	PF01048	0.745
MOD_GlcNHglycan	61	64	PF01048	0.839
MOD_GlcNHglycan	696	699	PF01048	0.622
MOD_GlcNHglycan	743	747	PF01048	0.681
MOD_GlcNHglycan	793	796	PF01048	0.680
MOD_GlcNHglycan	810	813	PF01048	0.482
MOD_GlcNHglycan	830	833	PF01048	0.600
MOD_GlcNHglycan	846	849	PF01048	0.794
MOD_GSK3_1	101	108	PF00069	0.849
MOD_GSK3_1	111	118	PF00069	0.636
MOD_GSK3_1	120	127	PF00069	0.664
MOD_GSK3_1	128	135	PF00069	0.607
MOD_GSK3_1	139	146	PF00069	0.554
MOD_GSK3_1	147	154	PF00069	0.580
MOD_GSK3_1	155	162	PF00069	0.567
MOD_GSK3_1	166	173	PF00069	0.545
MOD_GSK3_1	288	295	PF00069	0.769
MOD_GSK3_1	298	305	PF00069	0.568
MOD_GSK3_1	339	346	PF00069	0.690
MOD_GSK3_1	395	402	PF00069	0.852
MOD_GSK3_1	474	481	PF00069	0.547
MOD_GSK3_1	499	506	PF00069	0.654
MOD_GSK3_1	508	515	PF00069	0.608
MOD_GSK3_1	556	563	PF00069	0.606
MOD_GSK3_1	629	636	PF00069	0.738
MOD_GSK3_1	637	644	PF00069	0.661
MOD_GSK3_1	663	670	PF00069	0.791
MOD_GSK3_1	690	697	PF00069	0.648
MOD_GSK3_1	700	707	PF00069	0.716
MOD_GSK3_1	729	736	PF00069	0.561
MOD_GSK3_1	794	801	PF00069	0.502
MOD_GSK3_1	808	815	PF00069	0.606
MOD_GSK3_1	855	862	PF00069	0.751
MOD_N-GLC_2	786	788	PF02516	0.549
MOD_NEK2_1	107	112	PF00069	0.736
MOD_NEK2_1	136	141	PF00069	0.559
MOD_NEK2_1	270	275	PF00069	0.742
MOD_NEK2_1	281	286	PF00069	0.568
MOD_NEK2_1	373	378	PF00069	0.788
MOD_NEK2_1	384	389	PF00069	0.684
MOD_NEK2_1	571	576	PF00069	0.545
MOD_OFUCOSY	791	798	PF10250	0.661
MOD_OFUCOSY	803	809	PF10250	0.556
MOD_PIKK_1	246	252	PF00454	0.646
MOD_PIKK_1	340	346	PF00454	0.779
MOD_PIKK_1	536	542	PF00454	0.861
MOD_PIKK_1	578	584	PF00454	0.842
MOD_PIKK_1	602	608	PF00454	0.676
MOD_PIKK_1	700	706	PF00454	0.543
MOD_PIKK_1	80	86	PF00454	0.784
MOD_PIKK_1	853	859	PF00454	0.546
MOD_PK_1	544	550	PF00069	0.739
MOD_PK_1	663	669	PF00069	0.554
MOD_PK_1	708	714	PF00069	0.769
MOD_PKA_1	181	187	PF00069	0.516
MOD_PKA_1	246	252	PF00069	0.646
MOD_PKA_1	602	608	PF00069	0.677
MOD_PKA_1	663	669	PF00069	0.651
MOD_PKA_2	115	121	PF00069	0.852
MOD_PKA_2	245	251	PF00069	0.712
MOD_PKA_2	281	287	PF00069	0.754
MOD_PKA_2	373	379	PF00069	0.693
MOD_PKA_2	478	484	PF00069	0.760
MOD_PKA_2	497	503	PF00069	0.547
MOD_PKA_2	59	65	PF00069	0.766
MOD_PKA_2	601	607	PF00069	0.824
MOD_PKA_2	700	706	PF00069	0.751
MOD_PKA_2	96	102	PF00069	0.608
MOD_PKB_1	101	109	PF00069	0.849
MOD_Plk_1	384	390	PF00069	0.822
MOD_Plk_1	641	647	PF00069	0.732
MOD_Plk_1	652	658	PF00069	0.619
MOD_Plk_2-3	379	385	PF00069	0.825
MOD_Plk_2-3	508	514	PF00069	0.573
MOD_Plk_2-3	779	785	PF00069	0.800
MOD_Plk_4	298	304	PF00069	0.679
MOD_Plk_4	328	334	PF00069	0.564
MOD_Plk_4	379	385	PF00069	0.684
MOD_Plk_4	629	635	PF00069	0.737
MOD_Plk_4	642	648	PF00069	0.602
MOD_ProDKin_1	271	277	PF00069	0.741
MOD_ProDKin_1	323	329	PF00069	0.780
MOD_ProDKin_1	354	360	PF00069	0.694
MOD_ProDKin_1	395	401	PF00069	0.687
MOD_ProDKin_1	49	55	PF00069	0.756
MOD_ProDKin_1	519	525	PF00069	0.795
MOD_ProDKin_1	530	536	PF00069	0.730
MOD_ProDKin_1	557	563	PF00069	0.838
MOD_ProDKin_1	609	615	PF00069	0.735
MOD_ProDKin_1	618	624	PF00069	0.743
MOD_ProDKin_1	637	643	PF00069	0.790
MOD_ProDKin_1	645	651	PF00069	0.700
MOD_ProDKin_1	687	693	PF00069	0.782
MOD_ProDKin_1	71	77	PF00069	0.593
MOD_ProDKin_1	733	739	PF00069	0.786
MOD_ProDKin_1	798	804	PF00069	0.444
MOD_ProDKin_1	856	862	PF00069	0.734
MOD_SUMO_for_1	458	461	PF00179	0.581
MOD_SUMO_rev_2	626	633	PF00179	0.733
MOD_SUMO_rev_2	660	666	PF00179	0.554
TRG_DiLeu_BaEn_1	379	384	PF01217	0.827
TRG_DiLeu_BaEn_1	629	634	PF01217	0.654
TRG_DiLeu_BaLyEn_6	229	234	PF01217	0.585
TRG_DiLeu_BaLyEn_6	314	319	PF01217	0.799
TRG_ENDOCYTIC_2	482	485	PF00928	0.639
TRG_ENDOCYTIC_2	679	682	PF00928	0.540
TRG_ER_diArg_1	19	22	PF00400	0.753
TRG_ER_diArg_1	281	283	PF00400	0.610
TRG_ER_diArg_1	44	46	PF00400	0.847
TRG_ER_diArg_1	488	490	PF00400	0.804
TRG_ER_diArg_1	495	498	PF00400	0.721
TRG_ER_diArg_1	96	98	PF00400	0.823
TRG_NES_CRM1_1	259	272	PF08389	0.644
TRG_NLS_MonoCore_2	823	828	PF00514	0.563
TRG_NLS_MonoExtC_3	86	91	PF00514	0.850
TRG_NLS_MonoExtN_4	87	92	PF00514	0.850
TRG_Pf-PMV_PEXEL_1	232	236	PF00026	0.659

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8I8W5	Leishmania donovani	83%	99%
A4H9U3	Leishmania braziliensis	58%	99%
A4HUS7	Leishmania infantum	83%	99%
Q4QH65	Leishmania major	79%	100%