MORN repeat family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

MORN repeat, putative

Species:

Leishmania mexicana

UniProt:

E9ANF5_LEIMU

TriTrypDb:

LmxM.11.0090

Length:

526

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9ANF5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANF5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	170	174	PF00656	0.588
CLV_C14_Caspase3-7	400	404	PF00656	0.656
CLV_C14_Caspase3-7	449	453	PF00656	0.487
CLV_C14_Caspase3-7	510	514	PF00656	0.585
CLV_NRD_NRD_1	521	523	PF00675	0.627
CLV_PCSK_KEX2_1	21	23	PF00082	0.209
CLV_PCSK_KEX2_1	392	394	PF00082	0.607
CLV_PCSK_KEX2_1	521	523	PF00082	0.627
CLV_PCSK_PC1ET2_1	21	23	PF00082	0.209
CLV_PCSK_PC1ET2_1	392	394	PF00082	0.639
CLV_PCSK_SKI1_1	130	134	PF00082	0.417
CLV_PCSK_SKI1_1	228	232	PF00082	0.494
CLV_PCSK_SKI1_1	302	306	PF00082	0.661
CLV_PCSK_SKI1_1	521	525	PF00082	0.640
CLV_Separin_Metazoa	289	293	PF03568	0.661
DEG_APCC_DBOX_1	411	419	PF00400	0.572
DEG_COP1_1	187	197	PF00400	0.677
DEG_Nend_UBRbox_1	1	4	PF02207	0.355
DEG_SPOP_SBC_1	341	345	PF00917	0.419
DOC_CYCLIN_RxL_1	222	235	PF00134	0.617
DOC_PP1_RVXF_1	433	439	PF00149	0.631
DOC_PP2B_LxvP_1	101	104	PF13499	0.522
DOC_USP7_MATH_1	11	15	PF00917	0.408
DOC_USP7_MATH_1	136	140	PF00917	0.354
DOC_USP7_MATH_1	348	352	PF00917	0.710
DOC_USP7_MATH_1	77	81	PF00917	0.445
DOC_USP7_UBL2_3	228	232	PF12436	0.636
DOC_USP7_UBL2_3	69	73	PF12436	0.479
DOC_WW_Pin1_4	186	191	PF00397	0.702
DOC_WW_Pin1_4	195	200	PF00397	0.691
DOC_WW_Pin1_4	44	49	PF00397	0.479
DOC_WW_Pin1_4	96	101	PF00397	0.547
LIG_14-3-3_CanoR_1	222	228	PF00244	0.545
LIG_14-3-3_CanoR_1	258	268	PF00244	0.650
LIG_14-3-3_CanoR_1	302	308	PF00244	0.623
LIG_14-3-3_CanoR_1	32	39	PF00244	0.335
LIG_14-3-3_CanoR_1	332	338	PF00244	0.539
LIG_14-3-3_CanoR_1	406	412	PF00244	0.596
LIG_14-3-3_CanoR_1	446	451	PF00244	0.713
LIG_BRCT_BRCA1_1	59	63	PF00533	0.513
LIG_FHA_1	155	161	PF00498	0.397
LIG_FHA_1	213	219	PF00498	0.647
LIG_FHA_1	260	266	PF00498	0.660
LIG_FHA_1	308	314	PF00498	0.662
LIG_FHA_1	33	39	PF00498	0.447
LIG_FHA_1	379	385	PF00498	0.558
LIG_FHA_1	97	103	PF00498	0.634
LIG_FHA_2	183	189	PF00498	0.699
LIG_FHA_2	244	250	PF00498	0.578
LIG_FHA_2	447	453	PF00498	0.727
LIG_FHA_2	497	503	PF00498	0.519
LIG_FHA_2	508	514	PF00498	0.583
LIG_LIR_Apic_2	105	110	PF02991	0.506
LIG_LIR_Gen_1	487	498	PF02991	0.496
LIG_LIR_Gen_1	83	93	PF02991	0.577
LIG_LIR_Nem_3	229	234	PF02991	0.509
LIG_LIR_Nem_3	320	326	PF02991	0.601
LIG_LIR_Nem_3	487	493	PF02991	0.521
LIG_NRBOX	201	207	PF00104	0.711
LIG_PCNA_yPIPBox_3	222	231	PF02747	0.537
LIG_SH2_CRK	107	111	PF00017	0.595
LIG_SH2_NCK_1	107	111	PF00017	0.627
LIG_SH2_NCK_1	447	451	PF00017	0.610
LIG_SH2_SRC	135	138	PF00017	0.347
LIG_SH2_STAT5	118	121	PF00017	0.375
LIG_SH2_STAT5	266	269	PF00017	0.414
LIG_SH2_STAT5	85	88	PF00017	0.352
LIG_SH3_3	238	244	PF00018	0.673
LIG_SUMO_SIM_anti_2	310	316	PF11976	0.616
LIG_TRAF2_1	176	179	PF00917	0.677
LIG_TRAF2_1	185	188	PF00917	0.430
MOD_CDK_SPK_2	195	200	PF00069	0.420
MOD_CK1_1	189	195	PF00069	0.728
MOD_CK1_1	235	241	PF00069	0.651
MOD_CK1_1	276	282	PF00069	0.626
MOD_CK1_1	359	365	PF00069	0.704
MOD_CK1_1	410	416	PF00069	0.541
MOD_CK1_1	44	50	PF00069	0.479
MOD_CK1_1	445	451	PF00069	0.750
MOD_CK1_1	80	86	PF00069	0.475
MOD_CK1_1	96	102	PF00069	0.426
MOD_CK2_1	11	17	PF00069	0.379
MOD_CK2_1	136	142	PF00069	0.378
MOD_CK2_1	182	188	PF00069	0.725
MOD_CK2_1	452	458	PF00069	0.708
MOD_CK2_1	486	492	PF00069	0.540
MOD_CK2_1	496	502	PF00069	0.445
MOD_GlcNHglycan	157	160	PF01048	0.456
MOD_GlcNHglycan	237	240	PF01048	0.659
MOD_GlcNHglycan	350	353	PF01048	0.667
MOD_GlcNHglycan	428	431	PF01048	0.431
MOD_GlcNHglycan	468	471	PF01048	0.718
MOD_GlcNHglycan	58	62	PF01048	0.526
MOD_GlcNHglycan	78	82	PF01048	0.150
MOD_GSK3_1	182	189	PF00069	0.733
MOD_GSK3_1	222	229	PF00069	0.589
MOD_GSK3_1	303	310	PF00069	0.637
MOD_GSK3_1	359	366	PF00069	0.689
MOD_GSK3_1	374	381	PF00069	0.672
MOD_GSK3_1	442	449	PF00069	0.713
MOD_N-GLC_1	166	171	PF02516	0.642
MOD_N-GLC_1	223	228	PF02516	0.531
MOD_N-GLC_2	28	30	PF02516	0.479
MOD_NEK2_1	212	217	PF00069	0.628
MOD_NEK2_1	259	264	PF00069	0.643
MOD_NEK2_1	307	312	PF00069	0.635
MOD_NEK2_1	31	36	PF00069	0.479
MOD_NEK2_1	354	359	PF00069	0.589
MOD_NEK2_1	418	423	PF00069	0.533
MOD_NEK2_1	493	498	PF00069	0.526
MOD_NEK2_1	93	98	PF00069	0.632
MOD_NEK2_2	11	16	PF00069	0.403
MOD_NEK2_2	136	141	PF00069	0.416
MOD_NEK2_2	223	228	PF00069	0.567
MOD_NEK2_2	407	412	PF00069	0.621
MOD_PIKK_1	102	108	PF00454	0.603
MOD_PIKK_1	259	265	PF00454	0.675
MOD_PIKK_1	4	10	PF00454	0.479
MOD_PKA_2	257	263	PF00069	0.666
MOD_PKA_2	31	37	PF00069	0.429
MOD_PKA_2	445	451	PF00069	0.669
MOD_PKB_1	505	513	PF00069	0.590
MOD_Plk_1	223	229	PF00069	0.594
MOD_Plk_1	486	492	PF00069	0.622
MOD_Plk_2-3	397	403	PF00069	0.632
MOD_Plk_2-3	452	458	PF00069	0.485
MOD_Plk_4	11	17	PF00069	0.355
MOD_Plk_4	189	195	PF00069	0.736
MOD_Plk_4	226	232	PF00069	0.570
MOD_Plk_4	309	315	PF00069	0.620
MOD_Plk_4	486	492	PF00069	0.522
MOD_Plk_4	493	499	PF00069	0.441
MOD_ProDKin_1	186	192	PF00069	0.704
MOD_ProDKin_1	195	201	PF00069	0.699
MOD_ProDKin_1	44	50	PF00069	0.479
MOD_ProDKin_1	96	102	PF00069	0.540
MOD_SUMO_for_1	439	442	PF00179	0.659
MOD_SUMO_rev_2	448	456	PF00179	0.705
MOD_SUMO_rev_2	66	74	PF00179	0.458
TRG_ENDOCYTIC_2	323	326	PF00928	0.488
TRG_ENDOCYTIC_2	395	398	PF00928	0.540
TRG_ENDOCYTIC_2	64	67	PF00928	0.392
TRG_ENDOCYTIC_2	85	88	PF00928	0.528
TRG_ER_diArg_1	521	523	PF00400	0.627
TRG_Pf-PMV_PEXEL_1	521	526	PF00026	0.654

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HV83	Leptomonas seymouri	51%	78%
A0A1X0NVA0	Trypanosomatidae	32%	78%
A0A3Q8IHC4	Leishmania donovani	93%	100%
A0A3R7LGF2	Trypanosoma rangeli	30%	81%
A4H9U9	Leishmania braziliensis	83%	100%
A4HUS1	Leishmania infantum	93%	100%
D0A7P2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	81%
Q4QH71	Leishmania major	93%	100%
V5BB15	Trypanosoma cruzi	37%	81%