LeishMANIAdb
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Putative SNF2/RAD54 related DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative SNF2/RAD54 related DNA helicase
Gene product:
SNF2/RAD54 related DNA helicase, putative
Species:
Leishmania mexicana
UniProt:
E9ANF1_LEIMU
TriTrypDb:
LmxM.11.0050
Length:
958

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005657 replication fork 2 1
GO:0043596 nuclear replication fork 3 1
GO:0110165 cellular anatomical entity 1 3
GO:0016020 membrane 2 2

Expansion

Sequence features

E9ANF1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ANF1

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006259 DNA metabolic process 4 1
GO:0006275 regulation of DNA replication 6 1
GO:0006281 DNA repair 5 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0006950 response to stress 2 1
GO:0006974 DNA damage response 4 1
GO:0008152 metabolic process 1 1
GO:0008156 negative regulation of DNA replication 7 1
GO:0009892 negative regulation of metabolic process 4 1
GO:0009987 cellular process 1 1
GO:0010605 negative regulation of macromolecule metabolic process 5 1
GO:0019219 regulation of nucleobase-containing compound metabolic process 5 1
GO:0019222 regulation of metabolic process 3 1
GO:0031297 replication fork processing 6 1
GO:0031323 regulation of cellular metabolic process 4 1
GO:0031324 negative regulation of cellular metabolic process 5 1
GO:0033554 cellular response to stress 3 1
GO:0034641 cellular nitrogen compound metabolic process 3 1
GO:0043170 macromolecule metabolic process 3 1
GO:0044237 cellular metabolic process 2 1
GO:0044238 primary metabolic process 2 1
GO:0044260 obsolete cellular macromolecule metabolic process 3 1
GO:0045005 DNA-templated DNA replication maintenance of fidelity 5 1
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 6 1
GO:0046483 heterocycle metabolic process 3 1
GO:0048478 obsolete replication fork protection 6 1
GO:0048519 negative regulation of biological process 3 1
GO:0048523 negative regulation of cellular process 4 1
GO:0050789 regulation of biological process 2 1
GO:0050794 regulation of cellular process 3 1
GO:0050896 response to stimulus 1 1
GO:0051052 regulation of DNA metabolic process 5 1
GO:0051053 negative regulation of DNA metabolic process 6 1
GO:0051171 regulation of nitrogen compound metabolic process 4 1
GO:0051172 negative regulation of nitrogen compound metabolic process 5 1
GO:0051716 cellular response to stimulus 2 1
GO:0060255 regulation of macromolecule metabolic process 4 1
GO:0065007 biological regulation 1 1
GO:0071704 organic substance metabolic process 2 1
GO:0080090 regulation of primary metabolic process 4 1
GO:0090304 nucleic acid metabolic process 4 1
GO:0090329 regulation of DNA-templated DNA replication 7 1
GO:1901360 organic cyclic compound metabolic process 3 1
GO:2000104 negative regulation of DNA-templated DNA replication 8 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 11
GO:0003676 nucleic acid binding 3 11
GO:0003824 catalytic activity 1 11
GO:0004386 helicase activity 2 8
GO:0004518 nuclease activity 4 11
GO:0004519 endonuclease activity 5 11
GO:0005488 binding 1 11
GO:0005524 ATP binding 5 11
GO:0008094 ATP-dependent activity, acting on DNA 2 11
GO:0016491 oxidoreductase activity 2 10
GO:0016787 hydrolase activity 2 11
GO:0016788 hydrolase activity, acting on ester bonds 3 11
GO:0017076 purine nucleotide binding 4 11
GO:0030554 adenyl nucleotide binding 5 11
GO:0032553 ribonucleotide binding 3 11
GO:0032555 purine ribonucleotide binding 4 11
GO:0032559 adenyl ribonucleotide binding 5 11
GO:0035639 purine ribonucleoside triphosphate binding 4 11
GO:0036094 small molecule binding 2 11
GO:0043167 ion binding 2 11
GO:0043168 anion binding 3 11
GO:0051213 dioxygenase activity 3 10
GO:0097159 organic cyclic compound binding 2 11
GO:0097367 carbohydrate derivative binding 2 11
GO:0140097 catalytic activity, acting on DNA 3 11
GO:0140640 catalytic activity, acting on a nucleic acid 2 11
GO:0140657 ATP-dependent activity 1 11
GO:0140658 ATP-dependent chromatin remodeler activity 3 11
GO:1901265 nucleoside phosphate binding 3 11
GO:1901363 heterocyclic compound binding 2 11
GO:0004520 DNA endonuclease activity 5 1
GO:0004536 DNA nuclease activity 4 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 310 314 PF00656 0.503
CLV_C14_Caspase3-7 424 428 PF00656 0.433
CLV_C14_Caspase3-7 473 477 PF00656 0.530
CLV_C14_Caspase3-7 586 590 PF00656 0.351
CLV_NRD_NRD_1 155 157 PF00675 0.497
CLV_NRD_NRD_1 180 182 PF00675 0.583
CLV_NRD_NRD_1 384 386 PF00675 0.379
CLV_NRD_NRD_1 399 401 PF00675 0.174
CLV_NRD_NRD_1 409 411 PF00675 0.282
CLV_NRD_NRD_1 429 431 PF00675 0.601
CLV_NRD_NRD_1 692 694 PF00675 0.516
CLV_NRD_NRD_1 720 722 PF00675 0.671
CLV_NRD_NRD_1 739 741 PF00675 0.315
CLV_NRD_NRD_1 776 778 PF00675 0.446
CLV_NRD_NRD_1 809 811 PF00675 0.488
CLV_NRD_NRD_1 816 818 PF00675 0.399
CLV_NRD_NRD_1 847 849 PF00675 0.516
CLV_NRD_NRD_1 955 957 PF00675 0.637
CLV_PCSK_FUR_1 921 925 PF00082 0.500
CLV_PCSK_KEX2_1 180 182 PF00082 0.583
CLV_PCSK_KEX2_1 384 386 PF00082 0.378
CLV_PCSK_KEX2_1 399 401 PF00082 0.186
CLV_PCSK_KEX2_1 429 431 PF00082 0.639
CLV_PCSK_KEX2_1 487 489 PF00082 0.359
CLV_PCSK_KEX2_1 692 694 PF00082 0.514
CLV_PCSK_KEX2_1 719 721 PF00082 0.723
CLV_PCSK_KEX2_1 739 741 PF00082 0.577
CLV_PCSK_KEX2_1 776 778 PF00082 0.446
CLV_PCSK_KEX2_1 809 811 PF00082 0.460
CLV_PCSK_KEX2_1 816 818 PF00082 0.431
CLV_PCSK_KEX2_1 847 849 PF00082 0.563
CLV_PCSK_KEX2_1 923 925 PF00082 0.639
CLV_PCSK_PC1ET2_1 487 489 PF00082 0.330
CLV_PCSK_PC1ET2_1 923 925 PF00082 0.639
CLV_PCSK_PC7_1 483 489 PF00082 0.330
CLV_PCSK_SKI1_1 181 185 PF00082 0.577
CLV_PCSK_SKI1_1 192 196 PF00082 0.360
CLV_PCSK_SKI1_1 200 204 PF00082 0.170
CLV_PCSK_SKI1_1 273 277 PF00082 0.356
CLV_PCSK_SKI1_1 295 299 PF00082 0.330
CLV_PCSK_SKI1_1 399 403 PF00082 0.273
CLV_PCSK_SKI1_1 464 468 PF00082 0.296
CLV_PCSK_SKI1_1 723 727 PF00082 0.579
CLV_PCSK_SKI1_1 923 927 PF00082 0.623
CLV_Separin_Metazoa 407 411 PF03568 0.586
DEG_COP1_1 161 170 PF00400 0.328
DEG_Nend_UBRbox_2 1 3 PF02207 0.573
DOC_ANK_TNKS_1 513 520 PF00023 0.460
DOC_CDC14_PxL_1 172 180 PF14671 0.567
DOC_CDC14_PxL_1 222 230 PF14671 0.586
DOC_CKS1_1 325 330 PF01111 0.506
DOC_CYCLIN_yCln2_LP_2 121 127 PF00134 0.537
DOC_MAPK_DCC_7 52 61 PF00069 0.607
DOC_MAPK_gen_1 20 29 PF00069 0.455
DOC_MAPK_gen_1 399 408 PF00069 0.467
DOC_MAPK_gen_1 410 418 PF00069 0.458
DOC_MAPK_gen_1 487 498 PF00069 0.465
DOC_MAPK_gen_1 50 58 PF00069 0.633
DOC_MAPK_gen_1 719 730 PF00069 0.709
DOC_MAPK_gen_1 776 782 PF00069 0.420
DOC_MAPK_gen_1 847 853 PF00069 0.407
DOC_MAPK_HePTP_8 49 61 PF00069 0.605
DOC_MAPK_MEF2A_6 52 61 PF00069 0.599
DOC_MAPK_MEF2A_6 74 82 PF00069 0.337
DOC_PP1_RVXF_1 198 204 PF00149 0.395
DOC_PP1_RVXF_1 234 240 PF00149 0.586
DOC_PP1_RVXF_1 382 389 PF00149 0.594
DOC_PP1_RVXF_1 737 744 PF00149 0.516
DOC_PP1_RVXF_1 801 807 PF00149 0.532
DOC_PP1_RVXF_1 950 956 PF00149 0.659
DOC_PP2B_LxvP_1 406 409 PF13499 0.562
DOC_PP4_FxxP_1 147 150 PF00568 0.560
DOC_USP7_MATH_1 409 413 PF00917 0.562
DOC_USP7_MATH_1 428 432 PF00917 0.649
DOC_USP7_MATH_1 590 594 PF00917 0.692
DOC_USP7_MATH_1 60 64 PF00917 0.428
DOC_USP7_MATH_1 604 608 PF00917 0.644
DOC_USP7_MATH_1 647 651 PF00917 0.583
DOC_USP7_MATH_1 713 717 PF00917 0.638
DOC_USP7_UBL2_3 614 618 PF12436 0.621
DOC_WW_Pin1_4 324 329 PF00397 0.508
DOC_WW_Pin1_4 333 338 PF00397 0.461
DOC_WW_Pin1_4 371 376 PF00397 0.498
DOC_WW_Pin1_4 61 66 PF00397 0.539
DOC_WW_Pin1_4 685 690 PF00397 0.574
LIG_14-3-3_CanoR_1 180 184 PF00244 0.565
LIG_14-3-3_CanoR_1 439 445 PF00244 0.515
LIG_14-3-3_CanoR_1 50 59 PF00244 0.554
LIG_14-3-3_CanoR_1 582 588 PF00244 0.445
LIG_14-3-3_CanoR_1 594 599 PF00244 0.674
LIG_14-3-3_CanoR_1 646 654 PF00244 0.573
LIG_14-3-3_CanoR_1 723 729 PF00244 0.641
LIG_14-3-3_CanoR_1 803 807 PF00244 0.473
LIG_14-3-3_CanoR_1 816 820 PF00244 0.333
LIG_14-3-3_CanoR_1 935 939 PF00244 0.664
LIG_14-3-3_CanoR_1 952 956 PF00244 0.466
LIG_Actin_WH2_2 141 158 PF00022 0.587
LIG_BRCT_BRCA1_1 649 653 PF00533 0.689
LIG_BRCT_BRCA1_1 793 797 PF00533 0.545
LIG_BRCT_BRCA1_1 87 91 PF00533 0.522
LIG_Clathr_ClatBox_1 4 8 PF01394 0.644
LIG_CSL_BTD_1 700 703 PF09270 0.471
LIG_deltaCOP1_diTrp_1 671 680 PF00928 0.605
LIG_DLG_GKlike_1 594 602 PF00625 0.748
LIG_EH_1 340 344 PF12763 0.530
LIG_eIF4E_1 462 468 PF01652 0.378
LIG_FHA_1 130 136 PF00498 0.580
LIG_FHA_1 315 321 PF00498 0.478
LIG_FHA_1 381 387 PF00498 0.515
LIG_FHA_1 51 57 PF00498 0.626
LIG_FHA_1 638 644 PF00498 0.464
LIG_FHA_1 68 74 PF00498 0.437
LIG_FHA_1 725 731 PF00498 0.710
LIG_FHA_1 901 907 PF00498 0.335
LIG_FHA_1 935 941 PF00498 0.672
LIG_FHA_2 677 683 PF00498 0.572
LIG_FHA_2 911 917 PF00498 0.335
LIG_FHA_2 934 940 PF00498 0.692
LIG_GBD_Chelix_1 102 110 PF00786 0.472
LIG_Integrin_RGD_1 501 503 PF01839 0.386
LIG_Integrin_RGD_1 510 512 PF01839 0.279
LIG_LIR_Apic_2 745 751 PF02991 0.513
LIG_LIR_Gen_1 313 323 PF02991 0.491
LIG_LIR_Gen_1 340 349 PF02991 0.514
LIG_LIR_Gen_1 387 392 PF02991 0.542
LIG_LIR_Gen_1 460 469 PF02991 0.447
LIG_LIR_Gen_1 578 587 PF02991 0.451
LIG_LIR_Gen_1 651 662 PF02991 0.631
LIG_LIR_Gen_1 671 681 PF02991 0.269
LIG_LIR_Gen_1 939 950 PF02991 0.738
LIG_LIR_Nem_3 22 27 PF02991 0.513
LIG_LIR_Nem_3 223 228 PF02991 0.534
LIG_LIR_Nem_3 293 297 PF02991 0.506
LIG_LIR_Nem_3 313 319 PF02991 0.491
LIG_LIR_Nem_3 340 346 PF02991 0.514
LIG_LIR_Nem_3 372 376 PF02991 0.533
LIG_LIR_Nem_3 387 391 PF02991 0.542
LIG_LIR_Nem_3 460 465 PF02991 0.490
LIG_LIR_Nem_3 578 583 PF02991 0.434
LIG_LIR_Nem_3 651 657 PF02991 0.643
LIG_LIR_Nem_3 671 677 PF02991 0.286
LIG_LIR_Nem_3 88 94 PF02991 0.524
LIG_LIR_Nem_3 939 945 PF02991 0.750
LIG_LIR_Nem_3 954 958 PF02991 0.586
LIG_LYPXL_yS_3 225 228 PF13949 0.586
LIG_MYND_1 609 613 PF01753 0.593
LIG_Pex14_2 24 28 PF04695 0.493
LIG_Pex14_2 653 657 PF04695 0.623
LIG_Rb_LxCxE_1 293 315 PF01857 0.586
LIG_REV1ctd_RIR_1 804 814 PF16727 0.530
LIG_SH2_CRK 316 320 PF00017 0.491
LIG_SH2_CRK 368 372 PF00017 0.586
LIG_SH2_CRK 462 466 PF00017 0.378
LIG_SH2_GRB2like 440 443 PF00017 0.573
LIG_SH2_PTP2 779 782 PF00017 0.610
LIG_SH2_SRC 440 443 PF00017 0.573
LIG_SH2_SRC 760 763 PF00017 0.273
LIG_SH2_STAP1 17 21 PF00017 0.563
LIG_SH2_STAP1 316 320 PF00017 0.482
LIG_SH2_STAP1 440 444 PF00017 0.421
LIG_SH2_STAP1 462 466 PF00017 0.378
LIG_SH2_STAP1 724 728 PF00017 0.722
LIG_SH2_STAT5 246 249 PF00017 0.562
LIG_SH2_STAT5 316 319 PF00017 0.480
LIG_SH2_STAT5 368 371 PF00017 0.474
LIG_SH2_STAT5 376 379 PF00017 0.476
LIG_SH2_STAT5 567 570 PF00017 0.385
LIG_SH2_STAT5 654 657 PF00017 0.502
LIG_SH2_STAT5 742 745 PF00017 0.630
LIG_SH2_STAT5 748 751 PF00017 0.513
LIG_SH2_STAT5 779 782 PF00017 0.610
LIG_SH3_3 139 145 PF00018 0.503
LIG_SH3_3 147 153 PF00018 0.420
LIG_SH3_3 54 60 PF00018 0.591
LIG_SH3_3 869 875 PF00018 0.459
LIG_SH3_4 614 621 PF00018 0.621
LIG_SUMO_SIM_anti_2 34 40 PF11976 0.588
LIG_SUMO_SIM_anti_2 463 469 PF11976 0.579
LIG_SUMO_SIM_anti_2 849 855 PF11976 0.487
LIG_SUMO_SIM_par_1 273 278 PF11976 0.586
LIG_SUMO_SIM_par_1 74 79 PF11976 0.379
LIG_TRAF2_1 252 255 PF00917 0.530
LIG_TYR_ITIM 564 569 PF00017 0.453
LIG_UBA3_1 397 402 PF00899 0.482
LIG_UBA3_1 632 638 PF00899 0.527
LIG_WRC_WIRS_1 505 510 PF05994 0.377
LIG_WRC_WIRS_1 677 682 PF05994 0.550
MOD_CDK_SPxxK_3 685 692 PF00069 0.572
MOD_CK1_1 267 273 PF00069 0.567
MOD_CK1_1 593 599 PF00069 0.527
MOD_CK1_1 607 613 PF00069 0.609
MOD_CK1_1 63 69 PF00069 0.390
MOD_CK1_1 637 643 PF00069 0.509
MOD_CK1_1 648 654 PF00069 0.523
MOD_CK1_1 825 831 PF00069 0.465
MOD_CK1_1 948 954 PF00069 0.694
MOD_CK2_1 249 255 PF00069 0.586
MOD_CK2_1 357 363 PF00069 0.534
MOD_CK2_1 585 591 PF00069 0.634
MOD_CK2_1 676 682 PF00069 0.477
MOD_CMANNOS 732 735 PF00535 0.550
MOD_Cter_Amidation 845 848 PF01082 0.513
MOD_GlcNHglycan 116 119 PF01048 0.569
MOD_GlcNHglycan 137 140 PF01048 0.509
MOD_GlcNHglycan 309 312 PF01048 0.343
MOD_GlcNHglycan 333 336 PF01048 0.296
MOD_GlcNHglycan 430 433 PF01048 0.686
MOD_GlcNHglycan 45 48 PF01048 0.520
MOD_GlcNHglycan 709 712 PF01048 0.664
MOD_GlcNHglycan 715 718 PF01048 0.752
MOD_GlcNHglycan 754 757 PF01048 0.384
MOD_GlcNHglycan 798 801 PF01048 0.470
MOD_GlcNHglycan 810 813 PF01048 0.421
MOD_GlcNHglycan 87 90 PF01048 0.456
MOD_GSK3_1 387 394 PF00069 0.531
MOD_GSK3_1 590 597 PF00069 0.622
MOD_GSK3_1 614 621 PF00069 0.777
MOD_GSK3_1 63 70 PF00069 0.487
MOD_GSK3_1 648 655 PF00069 0.622
MOD_GSK3_1 676 683 PF00069 0.490
MOD_LATS_1 612 618 PF00433 0.595
MOD_N-GLC_1 307 312 PF02516 0.362
MOD_NEK2_1 104 109 PF00069 0.535
MOD_NEK2_1 114 119 PF00069 0.555
MOD_NEK2_1 135 140 PF00069 0.553
MOD_NEK2_1 179 184 PF00069 0.402
MOD_NEK2_1 19 24 PF00069 0.539
MOD_NEK2_1 304 309 PF00069 0.586
MOD_NEK2_1 331 336 PF00069 0.471
MOD_NEK2_1 357 362 PF00069 0.514
MOD_NEK2_1 391 396 PF00069 0.489
MOD_NEK2_1 474 479 PF00069 0.576
MOD_NEK2_1 504 509 PF00069 0.582
MOD_NEK2_1 583 588 PF00069 0.445
MOD_NEK2_1 598 603 PF00069 0.631
MOD_NEK2_1 634 639 PF00069 0.474
MOD_NEK2_1 653 658 PF00069 0.495
MOD_NEK2_1 680 685 PF00069 0.507
MOD_NEK2_1 752 757 PF00069 0.384
MOD_NEK2_1 796 801 PF00069 0.453
MOD_NEK2_2 802 807 PF00069 0.503
MOD_PIKK_1 267 273 PF00454 0.509
MOD_PIKK_1 570 576 PF00454 0.567
MOD_PIKK_1 598 604 PF00454 0.746
MOD_PK_1 74 80 PF00069 0.489
MOD_PKA_2 179 185 PF00069 0.469
MOD_PKA_2 19 25 PF00069 0.557
MOD_PKA_2 409 415 PF00069 0.595
MOD_PKA_2 428 434 PF00069 0.666
MOD_PKA_2 593 599 PF00069 0.582
MOD_PKA_2 645 651 PF00069 0.589
MOD_PKA_2 802 808 PF00069 0.469
MOD_PKA_2 815 821 PF00069 0.344
MOD_PKA_2 934 940 PF00069 0.672
MOD_PKA_2 951 957 PF00069 0.453
MOD_Plk_1 299 305 PF00069 0.509
MOD_Plk_1 312 318 PF00069 0.534
MOD_Plk_1 386 392 PF00069 0.496
MOD_Plk_1 67 73 PF00069 0.492
MOD_Plk_1 822 828 PF00069 0.506
MOD_Plk_1 894 900 PF00069 0.395
MOD_Plk_2-3 129 135 PF00069 0.585
MOD_Plk_2-3 249 255 PF00069 0.586
MOD_Plk_2-3 264 270 PF00069 0.409
MOD_Plk_4 230 236 PF00069 0.410
MOD_Plk_4 387 393 PF00069 0.482
MOD_Plk_4 474 480 PF00069 0.505
MOD_Plk_4 676 682 PF00069 0.538
MOD_Plk_4 802 808 PF00069 0.554
MOD_ProDKin_1 324 330 PF00069 0.508
MOD_ProDKin_1 333 339 PF00069 0.461
MOD_ProDKin_1 371 377 PF00069 0.498
MOD_ProDKin_1 61 67 PF00069 0.542
MOD_ProDKin_1 685 691 PF00069 0.572
MOD_SUMO_for_1 756 759 PF00179 0.372
TRG_DiLeu_BaEn_1 254 259 PF01217 0.377
TRG_DiLeu_BaEn_1 387 392 PF01217 0.482
TRG_DiLeu_BaLyEn_6 628 633 PF01217 0.551
TRG_DiLeu_LyEn_5 223 228 PF01217 0.562
TRG_ENDOCYTIC_2 225 228 PF00928 0.583
TRG_ENDOCYTIC_2 316 319 PF00928 0.491
TRG_ENDOCYTIC_2 368 371 PF00928 0.521
TRG_ENDOCYTIC_2 376 379 PF00928 0.501
TRG_ENDOCYTIC_2 462 465 PF00928 0.355
TRG_ENDOCYTIC_2 566 569 PF00928 0.454
TRG_ENDOCYTIC_2 654 657 PF00928 0.624
TRG_ENDOCYTIC_2 779 782 PF00928 0.605
TRG_ER_diArg_1 179 181 PF00400 0.561
TRG_ER_diArg_1 384 386 PF00400 0.569
TRG_ER_diArg_1 398 400 PF00400 0.396
TRG_ER_diArg_1 49 52 PF00400 0.573
TRG_ER_diArg_1 718 721 PF00400 0.717
TRG_ER_diArg_1 738 740 PF00400 0.607
TRG_ER_diArg_1 808 810 PF00400 0.503
TRG_ER_diArg_1 815 817 PF00400 0.438
TRG_NES_CRM1_1 241 255 PF08389 0.534
TRG_NES_CRM1_1 68 81 PF08389 0.528
TRG_NLS_Bipartite_1 399 414 PF00514 0.586
TRG_NLS_MonoExtN_4 409 414 PF00514 0.586
TRG_Pf-PMV_PEXEL_1 200 205 PF00026 0.362
TRG_Pf-PMV_PEXEL_1 355 359 PF00026 0.177
TRG_Pf-PMV_PEXEL_1 399 403 PF00026 0.282
TRG_Pf-PMV_PEXEL_1 585 589 PF00026 0.524
TRG_Pf-PMV_PEXEL_1 918 922 PF00026 0.607

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IHR1 Leptomonas seymouri 57% 99%
A0A1X0NWY2 Trypanosomatidae 40% 97%
A0A3Q8I7U7 Leishmania donovani 93% 100%
A0A3R7RKP1 Trypanosoma rangeli 41% 97%
A4H9V3 Leishmania braziliensis 82% 100%
A4HUR7 Leishmania infantum 93% 100%
D0A7P6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 40% 100%
Q4QH75 Leishmania major 91% 100%
V5BRH2 Trypanosoma cruzi 42% 98%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS